Preparation method and application of a kind of nanosheet adhesive of fast-adhesion hydrogel
The nanosheet adhesive prepared by combining inorganic salts, organic ligands and solvents solves the problem of traditional adhesives being unable to adhere to hydrogels, achieving rapid and stable hydrogel adhesion, and is suitable for various environments.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- ZHENGZHOU UNIV
- Filing Date
- 2025-03-11
- Publication Date
- 2026-07-21
AI Technical Summary
Traditional adhesives are difficult to adhere to hydrogels effectively, especially during the swelling process of hydrogels, and often require conditions such as chemical reaction, heating, pH change or electric field, resulting in poor applicability.
A combination of inorganic salts, organic ligands, and solvents was used to prepare nanosheet adhesives through ultrasonic dispersion and stirring. The solvent was used to remove moisture from the surface of the hydrogel, reduce the local dielectric constant, and enhance electrostatic interactions, enabling rapid adhesion through nanosheet stacking.
It achieves rapid and stable adhesion of hydrogels at room temperature, is resistant to water and high and low temperatures, has strong adhesion in a variety of solvents, and is simple to prepare and saves energy.
Smart Images
Figure CN120137590B_ABST
Abstract
Description
Technical Field
[0001] This invention belongs to the field of adhesive preparation technology, specifically relating to a method for preparing and applying a nanosheet adhesive for rapid adhesion of hydrogels. Background Technology
[0002] Wet adhesion plays a crucial role in biomedicine and biotechnology, as well as more traditional coating and materials technologies. However, the development of adhesives specifically for adhering hydrogels is extremely limited. Traditional adhesives are typically polymers, but bonding hydrogels together using polymers is very difficult, requiring chemical reactions, heating, pH changes, ultraviolet radiation, or electric fields. Furthermore, hydrogels exhibit swelling properties, and common adhesives often fail to maintain good adhesion during the swelling process, leading to adhesive failure. Different types of hydrogels vary significantly in chemical composition and physical properties, making it difficult for general adhesives to achieve effective adhesion to most hydrogels. Summary of the Invention
[0003] One object of the present invention is to solve at least the above-mentioned problems and / or defects, and to provide at least the advantages described below.
[0004] To achieve these objectives and other advantages of the present invention, a method for preparing a nanosheet adhesive for rapid adhesion of hydrogels is provided, comprising the following steps: dissolving an inorganic salt in a solvent, then ultrasonically dispersing it uniformly, subsequently adding a modifier and an organic ligand, and stirring uniformly at room temperature to obtain the nanosheet adhesive.
[0005] Preferably, the inorganic salt is one or more of calcium nitrate tetrahydrate, calcium nitrite, aluminum nitrate nonahydrate, and magnesium nitrate hexahydrate.
[0006] Preferably, the regulator is N,N-diisopropylethylamine.
[0007] Preferably, the organic ligand is one or more of terephthalic acid, 2-aminoterephthalic acid, and 2-hydroxyterephthalic acid.
[0008] Preferably, the solvent is anhydrous ethanol.
[0009] Preferably, the molar ratio of the inorganic salt, regulator, and organic ligand is 1:1 to 10:0.5 to 2; and the molar concentration of the inorganic salt in the solvent is 0.015 to 1.5 mol / L.
[0010] Preferably, the ultrasonic dispersion frequency is 20-40 kHz, the ultrasonic dispersion time is 30-45 min, and the stirring reaction time is 2-8 h.
[0011] Preferably, when preparing the nanosheet adhesive, after adding inorganic salt to the solvent, an alcohol-soluble protein additive can also be added to the solvent. The specific method is as follows: first, dissolve the alcohol-soluble protein additive in 80% ethanol to obtain an alcohol-soluble protein additive solution, and then add it to the system; wherein, the amount of alcohol-soluble protein additive is 0.1 to 0.5 wt% of the solvent, and the mass ratio of alcohol-soluble protein additive to ethanol is 2 to 3: 80 to 100.
[0012] Preferably, the preparation method of the alcohol-soluble protein additive is as follows: dissolve zein in acetone solution, stir evenly, add lignin, continue stirring until viscous, and then heat to evaporate the solvent to obtain the alcohol-soluble protein additive; wherein, the mass ratio of zein, lignin and acetone solution is 1:0.2-0.4:1.5-2, the concentration of acetone solution is 70-80%, stirring is performed for 1-2 minutes, the heating temperature is 55-65℃, and heating is performed for 2-4 hours.
[0013] This invention also provides an application of nanosheet adhesive, which is used to quickly adhere hydrogels. In use, the nanosheet adhesive is first sprayed onto the surface of one hydrogel, and another hydrogel adheres to it. With gentle pressing, adhesion can be completed within 10 seconds.
[0014] The present invention offers at least the following advantages: The nanosheet adhesive of the present invention removes water from the surface of the hydrogel by first using solvents and modifiers in the adhesive, and then nanosheets are deposited on the hydrogel surface, thereby reducing the local dielectric constant and enhancing electrostatic interactions to achieve rapid adhesion. The nanosheets fix the solvent and modifier between the hydrogel and the nanosheets, thus maintaining adhesion even as the hydrogel swells. Furthermore, due to the presence of pores on the surface of the nanosheet adhesive, the hydrogel network can penetrate the nanosheet adhesive, allowing it to adhere tightly to the hydrogel surface. Simultaneously, the nanosheet adhesive prepared by the present invention is a white gel-like liquid, easy to store, and exhibits long-term stability. The preparation method is simple, requiring no heating, pressurization, or irradiation with a specific wavelength light source; it can be prepared by stirring at room temperature, thus saving energy. The nanosheet adhesive for rapid adhesion of hydrogels of the present invention is water-resistant and exhibits strong adhesion at low and high temperatures and in various solvents, maintaining high adhesion strength even after multiple cycles.
[0015] Other advantages, objectives and features of the present invention will become apparent in part from the following description, and in part from those skilled in the art through study and practice of the invention. Attached Figure Description
[0016] Figure 1 The infrared spectrum of the nanosheet adhesive prepared in Example 1 of this invention;
[0017] Figure 2The image shows the XRD pattern of the nanosheet adhesive prepared in Example 1 of this invention.
[0018] Figure 3 This is a SEM cross-sectional image of the nanosheet adhesive prepared in Example 1 of the present invention adhering to the surface of a hydrogel.
[0019] Figure 4 The image shown is the AFM image of the nanosheet adhesive prepared in Example 1 of this invention.
[0020] Figure 5 The water vapor adsorption-desorption curve of the nanosheet adhesive prepared in Example 1 of this invention;
[0021] Figure 6 Photographs of the nanosheet adhesive adhering to the hydrogel prepared in Example 1 of the present invention (left is treated with methyl orange staining);
[0022] Figure 7 This is a photograph of the nanosheet adhesive prepared in Example 1 of the present invention immersed in water while adhering to a hydrogel. Detailed implementation method:
[0023] The present invention will now be described in further detail with reference to the accompanying drawings, so that those skilled in the art can implement it based on the description.
[0024] It should be understood that terms such as “having,” “comprising,” and “including” as used herein do not exclude the presence or addition of one or more other elements or combinations thereof.
[0025] Example 1
[0026] A method for preparing a nanosheet adhesive for rapid adhesion of hydrogels includes the following steps:
[0027] 0.015 mol calcium nitrate tetrahydrate was dissolved in 1 L of anhydrous ethanol and ultrasonically dispersed at 25 kHz for 30 min. After uniform dispersion, 0.015 mol N,N-diisopropylethylamine and 0.015 mol terephthalic acid were added, and the mixture was stirred at room temperature for 8 h to obtain nanosheet adhesive.
[0028] Application of a nanosheet adhesive for rapid adhesion of hydrogels: The prepared nanosheet adhesive is sprayed onto a polyacrylamide hydrogel, and another hydrogel sheet is placed on top of the adhesive. Two gentle presses are applied to expel air, and the two hydrogel sheets adhere in 10 seconds.
[0029] Figure 1 The infrared spectrum of the nanosheet adhesive prepared in this embodiment; from Figure 1 It can be seen that,
[0030] The infrared peak of the adhesive in Example 1 is at 511 cm⁻¹. -1626cm -1 867cm -1 The characteristic peak of Ca-O is at 1386 cm⁻¹. -1 1558cm -1 This is a characteristic peak of terephthalic acid.
[0031] Figure 2 The image shows the XRD pattern of the nanosheet adhesive prepared in this embodiment; from Figure 2 It can be seen that there are diffraction peaks at 2θ = 13° and 25°, corresponding to the 101 and 202 crystal planes, indicating the successful synthesis of the nanosheet adhesive for rapid adhesion of hydrogel in Example 1.
[0032] Figure 3 This is a SEM cross-sectional image of the nanosheet adhesive prepared in this embodiment adhering to the surface of the hydrogel. Figure 3 It can be seen that the nanosheet adhesive that rapidly adheres to the hydrogel has a sheet-like morphology and is more likely to accumulate on the surface of the hydrogel.
[0033] Figure 4 The image shows the AFM pattern of the nanosheet adhesive prepared in this embodiment. The thickness of the nanosheet is approximately 100 nm. Figure 5 The water vapor adsorption-desorption curves of the nanosheet adhesive prepared in this embodiment are shown below. Figure 5 It can be seen that the nanosheet adhesive that rapidly adheres to the hydrogel can adsorb water vapor, and some water remains unadsorbed during the desorption process.
[0034] Example 2
[0035] The difference between this embodiment and Example 1 is that the organic ligand used is 0.015 mol of 2-hydroxyterephthalic acid, while all other aspects are the same as in Example 1.
[0036] Example 3
[0037] The difference between this embodiment and Example 1 is that the organic ligand used is 0.015 mol of 2-aminoterephthalic acid, while all other aspects are the same as in Example 1.
[0038] Example 4
[0039] The difference between this embodiment and Example 1 is that 0.015 mol of calcium nitrite is used as the inorganic salt, while everything else is the same as in Example 1.
[0040] Example 5
[0041] The difference between this embodiment and Example 1 is that 0.015 mol of aluminum nitrate nonahydrate was used as the inorganic salt, while all other aspects are the same as in Example 1.
[0042] Example 6
[0043] The difference between this embodiment and Example 1 is that 0.015 mol of magnesium nitrate hexahydrate was used as the inorganic salt, while all other aspects are the same as in Example 1.
[0044] Example 7
[0045] A method for preparing a nanosheet adhesive for rapid adhesion of hydrogels includes the following steps:
[0046] Dissolve 100g of zein in 150g of 80wt% acetone solution, stir well, add 20g of lignin, continue stirring for 20min until it becomes viscous, and then heat at 58℃ for 2.5h to evaporate the solvent to obtain zein additive.
[0047] 0.015 mol calcium nitrate tetrahydrate was dissolved in 1 L of anhydrous ethanol, and then 1.58 g of alcohol-soluble protein additive was dissolved in 100 mL of 80% ethanol to obtain an alcohol-soluble protein additive solution. This solution was then added to the calcium nitrate solution and ultrasonically dispersed at 25 kHz for 30 min. After uniform dispersion, 0.015 mol N,N-diisopropylethylamine and 0.015 mol terephthalic acid were added, and the mixture was stirred at room temperature for 8 h to obtain the nanosheet adhesive.
[0048] Application of a nanosheet adhesive for rapid adhesion of hydrogels: The prepared nanosheet adhesive is sprayed onto a polyacrylamide hydrogel, and another hydrogel sheet is placed on top of the adhesive. Two gentle presses are applied to expel air, and the two hydrogel sheets adhere in 10 seconds.
[0049] Example 8
[0050] A method for preparing a nanosheet adhesive for rapid adhesion of hydrogels includes the following steps:
[0051] Dissolve 100g of zein in 150g of 80wt% acetone solution, stir well, add 20g of lignin, continue stirring for 20min until it becomes viscous, and then heat at 58℃ for 2.5h to evaporate the solvent to obtain zein additive.
[0052] 0.015 mol of calcium nitrate tetrahydrate was dissolved in 1 L of anhydrous ethanol. Then, 2.36 g of alcohol-soluble protein additive was dissolved in 100 mL of 80% ethanol to obtain an alcohol-soluble protein additive solution. This solution was then added to the calcium nitrate solution and ultrasonically dispersed at 25 kHz for 30 min. After uniform dispersion, 0.015 mol of N,N-diisopropylethylamine and 0.015 mol of terephthalic acid were added, and the mixture was stirred at room temperature for 8 h to obtain a nanosheet adhesive.
[0053] Example 9
[0054] A method for preparing a nanosheet adhesive for rapid adhesion of hydrogels includes the following steps:
[0055] Dissolve 100g of zein in 150g of 80wt% acetone solution, stir well, add 20g of lignin, continue stirring for 20min until it becomes viscous, and then heat at 58℃ for 2.5h to evaporate the solvent to obtain zein additive.
[0056] 0.015 mol of calcium nitrate tetrahydrate was dissolved in 1 L of anhydrous ethanol. Then, 3.16 g of alcohol-soluble protein additive was dissolved in 100 mL of 80% ethanol to obtain an alcohol-soluble protein additive solution. This solution was then added to the calcium nitrate solution and ultrasonically dispersed at 25 kHz for 30 min. After uniform dispersion, 0.015 mol of N,N-diisopropylethylamine and 0.015 mol of terephthalic acid were added, and the mixture was stirred at room temperature for 8 h to obtain the nanosheet adhesive.
[0057] Comparative Example 1 (Comparative Examples 1-6 are different inorganic salts)
[0058] A method for preparing a nanosheet adhesive for rapid adhesion of hydrogels includes the following steps:
[0059] 0.015 mol of calcium bromide in water was dissolved in 1 L of anhydrous ethanol and ultrasonically dispersed at 25 kHz for 30 min. After uniform dispersion, 0.015 mol of N,N-diisopropylethylamine and 0.015 mol of terephthalic acid were added, and the mixture was stirred at room temperature for 8 h to obtain nanosheet adhesive.
[0060] Comparative Example 2
[0061] A method for preparing a nanosheet adhesive for rapid adhesion of hydrogels includes the following steps:
[0062] 0.015 mol of calcium acetate monohydrate was dissolved in 1 L of anhydrous ethanol and ultrasonically dispersed at 25 kHz for 30 min. After uniform dispersion, 0.015 mol of N,N-diisopropylethylamine and 0.015 mol of terephthalic acid were added, and the mixture was stirred at room temperature for 8 h to obtain nanosheet adhesive.
[0063] Comparative Example 3
[0064] A method for preparing a nanosheet adhesive for rapid adhesion of hydrogels includes the following steps:
[0065] 0.015 mol magnesium chloride hexahydrate was dissolved in 1 L of anhydrous ethanol and ultrasonically dispersed at 25 kHz for 30 min. After uniform dispersion, 0.015 mol N,N-diisopropylethylamine and 0.015 mol terephthalic acid were added, and the mixture was stirred at room temperature for 8 h to obtain nanosheet adhesive.
[0066] Comparative Example 4
[0067] A method for preparing a nanosheet adhesive for rapid adhesion of hydrogels includes the following steps:
[0068] 0.015 mol magnesium bromide hexahydrate was dissolved in 1 L of anhydrous ethanol and ultrasonically dispersed at 25 kHz for 30 min. After uniform dispersion, 0.015 mol N,N-diisopropylethylamine and 0.015 mol terephthalic acid were added, and the mixture was stirred at room temperature for 8 h to obtain nanosheet adhesive.
[0069] Comparative Example 5
[0070] A method for preparing a nanosheet adhesive for rapid adhesion of hydrogels includes the following steps:
[0071] 0.015 mol magnesium acetate tetrahydrate was dissolved in 1 L of anhydrous ethanol and ultrasonically dispersed at 25 kHz for 30 min. After uniform dispersion, 0.015 mol N,N-diisopropylethylamine and 0.015 mol terephthalic acid were added, and the mixture was stirred at room temperature for 8 h to obtain nanosheet adhesive.
[0072] Comparative Example 6
[0073] A method for preparing a nanosheet adhesive for rapid adhesion of hydrogels includes the following steps:
[0074] 0.015 mol of calcium chloride dihydrate was dissolved in 1 L of anhydrous ethanol and ultrasonically dispersed at 25 kHz for 30 min. After uniform dispersion, 0.015 mol of N,N-diisopropylethylamine and 0.015 mol of terephthalic acid were added, and the mixture was stirred at room temperature for 8 h to obtain nanosheet adhesive.
[0075] Comparative Example 7 (Comparative Examples 7-8 use different organic ligands)
[0076] A method for preparing a nanosheet adhesive for rapid adhesion of hydrogels includes the following steps:
[0077] 0.015 mol calcium nitrate tetrahydrate was dissolved in 1 L of anhydrous ethanol and ultrasonically dispersed at 25 kHz for 30 min. After uniform dispersion, 0.015 mol N,N-diisopropylethylamine and 0.015 mol 2-fluoroterephthalic acid were added, and the mixture was stirred at room temperature for 8 h to obtain nanosheet adhesive.
[0078] Comparative Example 8
[0079] A method for preparing a nanosheet adhesive for rapid adhesion of hydrogels includes the following steps:
[0080] 0.015 mol calcium nitrate tetrahydrate was dissolved in 1 L of anhydrous ethanol and ultrasonically dispersed at 25 kHz for 30 min. After uniform dispersion, 0.015 mol N,N-diisopropylethylamine and 0.015 mol tetrafluoroterephthalic acid were added, and the mixture was stirred at room temperature for 8 h to obtain nanosheet adhesive.
[0081] Comparative Example 9 (without lignin)
[0082] A method for preparing a nanosheet adhesive for rapid adhesion of hydrogels includes the following steps:
[0083] 0.015 mol calcium nitrate tetrahydrate was dissolved in 1 L of anhydrous ethanol. Then, 1.58 g of zein was dissolved in 100 mL of 80% ethanol and added to the calcium nitrate solution. The mixture was then ultrasonically dispersed at 25 kHz for 30 min. After uniform dispersion, 0.015 mol N,N-diisopropylethylamine and 0.015 mol terephthalic acid were added, and the mixture was stirred at room temperature for 8 h to obtain the nanosheet adhesive.
[0084] Comparative Example 10 (without zein)
[0085] A method for preparing a nanosheet adhesive for rapid adhesion of hydrogels includes the following steps:
[0086] 0.015 mol of calcium nitrate tetrahydrate was dissolved in 1 L of anhydrous ethanol. Then, 1.58 g of lignin was dissolved in 100 mL of 80% ethanol and added to the calcium nitrate solution. The mixture was then ultrasonically dispersed at 25 kHz for 30 min. After uniform dispersion, 0.015 mol of N,N-diisopropylethylamine and 0.015 mol of terephthalic acid were added. The mixture was stirred at room temperature for 8 h to obtain the nanosheet adhesive.
[0087] The nanosheet adhesives prepared in Examples 1-9 and Comparative Examples 1-8 were used to bond polyacrylamide hydrogels. The method was as follows: the prepared nanosheet adhesive was sprayed onto the polyacrylamide hydrogel, and another piece of polyacrylamide hydrogel was placed on top of the adhesive. The two pieces of hydrogel were gently pressed twice to expel air, and the two pieces of hydrogel were adhered in 10 seconds. The adhesion strength of the finally bonded hydrogels was tested, and the test results are shown in Table 1 below.
[0088] Table 1 Adhesion strength of the examples and comparative examples
[0089] Adhesion strength (Pa) 3863 3121 3727 3719 3072 3541 4102 4227 4396 Comparative Example 1 2 3 4 5 6 7 8 9 10 Adhesion strength (Pa) 2492 2936 2122 2753 1716 2885 2538 2417 3995 3861
[0090] As can be seen from Table 1, the inorganic salts used in Examples 1-6 of this invention differ from those used in Comparative Examples 1-6 in that the selected inorganic salt anions are different. The adhesives prepared with nitrates in Examples 1-6 have higher adhesion strength because nitrates have relatively low lattice energy, making it easier for nitrate ions to form hydrogen bonds. Therefore, the adhesives prepared in these examples have higher adhesion strength. Similarly, the organic ligands used in Examples 1-6 of this invention differ from those used in Comparative Examples 7-8. The fluorine-containing ligands in Comparative Examples 7-8 have hydrophobic properties and are unevenly dispersed in the solvent, resulting in lower adhesion strength. The organic ligands used in Examples 1-6 are non-hydrophobic, thus the adhesives prepared in these examples have higher adhesion strength. The adhesive exhibits higher adhesion strength. Furthermore, in Examples 7-9, based on Example 1, an alcohol-soluble protein additive was introduced into the adhesive system. The film-forming properties of zein and the multifunctional structure of lignin can form a dense adhesion layer at the interface, enhancing the interaction with the substrate and further improving the adhesion strength of the adhesive. Meanwhile, as shown in Table 4, the adhesion strength of the nanosheet adhesive underwater is also improved. This is because the hydrophobicity of zein and lignin works together to effectively repel water and reduce the interference of water molecules on the adhesion interface in the underwater environment. Moreover, the lignin molecular structure remains stable underwater and is not easily hydrolyzed, thereby improving the underwater adhesion performance.
[0091] Application Example 1
[0092] The nanosheet adhesive prepared in Example 1 was used to bond polyethylene glycol hydrogel, sodium alginate hydrogel, polyacrylic acid hydrogel and polyvinyl alcohol hydrogel respectively, and the adhesion strength was tested. The results are shown in Table 2 below.
[0093] Table 2 Adhesion strength when bonding different hydrogels
[0094] Adhesion strength (Pa) 3632 3150 3562 3655
[0095] The adhesion strength of the nanosheet adhesive bonded to the polyacrylamide hydrogel in Example 1 was tested by a cyclic adhesion test, and the results are shown in Table 3.
[0096] Table 3. Adhesion strength of the nanosheet adhesive viscous hydrogel in Example 1.
[0097] Adhesion strength (Pa) 3863 3236 3236 3203 3138 3039 2776 2348 2052 1953
[0098] The adhesion strength of the nanosheet adhesives used in Examples 1, 7, and Comparative Examples 9-10, after bonding with polyacrylamide hydrogels, was tested by immersing them in water for different times. The adhesion strength is shown in Table 4.
[0099] Table 4 shows the adhesion strength of the nanosheet adhesives used in Examples 1 and 7-9 after immersion in water for different times.
[0100] Example 1: Adhesion Strength (Pa) 4400 4300 4217 3576 3272 Example 7 Adhesion Strength (Pa) 4652 4541 4414 3639 3399 Comparative Example 9 Adhesion Strength (Pa) 4472 4325 4276 3570 3314 Comparative Example 10 Adhesion Strength (Pa) 4518 4371 4301 3608 3385
[0101] (It should be noted that the adhesion strength of the nanosheet adhesive is further improved in water compared to in air.)
[0102] The adhesion strength of the nanosheet adhesive of Example 1 bonded to the polyacrylamide hydrogel was tested after being immersed in different solvents. The adhesion strength is shown in Table 5.
[0103] Table 5. Adhesion strength of the nanosheet adhesive for the hydrogel in different solvents in Example 1.
[0104] Adhesion strength (Pa) 4400 2634 2349 1148 1632
[0105] The adhesion strength of the nanosheet adhesive used in Example 1, after bonding the polyacrylamide hydrogel, was tested by immersing it in water at different temperatures. The adhesion strength is shown in Table 6.
[0106] Table 6. Adhesion strength of the nanosheet adhesive for the hydrogel in water at different temperatures in Example 1.
[0107] Adhesion strength (Pa) 3995 4348 4400 3952 3065
[0108] The adhesion strength of the nanosheet adhesive of Example 1 to polyacrylamide hydrogels with different swelling ratios is shown in Table 7.
[0109] Table 7. Adhesion strength of nanosheet adhesives to hydrogels with different swelling ratios in Example 1.
[0110] Adhesion strength (Pa) 2945 2709 2435 2164 1935
[0111] Although embodiments of the present invention have been disclosed above, they are not limited to the applications listed in the specification and embodiments. They can be applied to various fields suitable for the present invention. For those skilled in the art, other modifications can be easily made. Therefore, without departing from the general concept defined by the claims and their equivalents, the present invention is not limited to the specific details and illustrations shown and described herein.
Claims
1. A method for preparing a nanosheet adhesive for rapid adhesion of hydrogels, characterized in that, Includes the following steps: Inorganic salts were dissolved in a solvent, alcohol-soluble protein additives were added to the solvent, and then the mixture was ultrasonically dispersed. Subsequently, regulators and organic ligands were added, and the mixture was stirred at room temperature to obtain nanosheet adhesives. The regulator is N,N-diisopropylethylamine; When preparing the nanosheet adhesive, the specific method for adding an alcohol-soluble protein additive to the solvent after adding an inorganic salt is as follows: first, dissolve the alcohol-soluble protein additive in 80% ethanol to obtain an alcohol-soluble protein additive solution, and then add it to the system; wherein, the amount of alcohol-soluble protein additive is 0.1~0.5wt% of the solvent, and the mass ratio of alcohol-soluble protein additive to ethanol is 2~3:80~100; The preparation method of the alcohol-soluble protein additive is as follows: dissolve zein in acetone solution, stir evenly, add lignin, continue stirring until viscous, and then heat to evaporate the solvent to obtain the alcohol-soluble protein additive; wherein, the mass ratio of zein, lignin and acetone solution is 1:0.2~0.4:1.5~2, the concentration of acetone solution is 70~80%, stirring for 1~2 min, heating temperature is 55~65℃, and heating for 2~4 h; The inorganic salt is one or more of calcium nitrate tetrahydrate, calcium nitrite, aluminum nitrate nonahydrate, and magnesium nitrate hexahydrate; The organic ligand is one or more of terephthalic acid, 2-aminoterephthalic acid, and 2-hydroxyterephthalic acid; The molar ratio of the inorganic salt, regulator, and organic ligand is 1:1~10:0.5~2; the molar concentration of the inorganic salt in the solvent is 0.015~1.5 mol / L.
2. The method for preparing the nanosheet adhesive for rapid adhesion of hydrogels as described in claim 1, characterized in that, The solvent is anhydrous ethanol.
3. The method for preparing the nanosheet adhesive for rapid adhesion of hydrogels as described in claim 1, characterized in that, The ultrasonic dispersion frequency is 20~40kHz, the ultrasonic dispersion time is 30~45min, and the stirring reaction time is 2~8h.
4. The application of a nanosheet adhesive prepared by the preparation method according to any one of claims 1-3, characterized in that, When using it to quickly adhere hydrogels, first spray the nanosheet adhesive onto the surface of one hydrogel, and then attach another hydrogel onto it. Press gently, and adhesion can be completed within 10 seconds.