A duplex portable enzymatic analyzer and a method of using the same

Abstract

The present application belongs to the technical field of medical apparatus and instruments, and particularly relates to a double portable enzymatic analyzer and a use method thereof. The analyzer is wrapped by a packaging shell to cover an internal functional system, and the functional system covers a general control unit, a mounting bottom plate and two detection units. The detection unit contains vertical guidance, floating lifting, test paper placement and driving mechanism, etc., and each component is designed ingeniously. The use method starts from self-checking and preheating, and goes through sample preparation, detection, cleaning and resetting, etc. Compared with the prior art, the present application has obvious advantages, can detect glutamic-oxalacetic transaminase and glutamic-pyruvic transaminase at the same time, improves the detection efficiency and reduces the operation error; is small in size and convenient to carry, and is suitable for various scenes; is reasonable in structural design, stable in operation and small in instrument volume; is simple to operate, has a self-checking and preheating function, an intuitive interface, and a humanized test paper placement mechanism, and greatly improves the use convenience.

Description

Technical Field

[0001] This invention belongs to the field of medical device technology, and in particular relates to a dual-portable enzyme analyzer and its usage method. Background Technology

[0002] Enzyme detection plays a crucial role in modern medical diagnostics and numerous biochemical research fields. Among these, the determination of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels are key indicators for assessing liver function, myocardial function, and other health conditions. While existing enzyme analyzers on the market meet basic testing needs to some extent, they still have many limitations.

[0003] In terms of detection channels, single-channel enzymology instruments have limited functionality. Because they only have a single detection pathway, they cannot simultaneously detect alanine aminotransferase (ALT) and aspartate aminotransferase (AST). This means that in actual testing, to obtain data for both enzymes, the instrument must be used twice for independent testing, which not only consumes a lot of time but also increases sample volume, introduces more operational errors, and reduces testing efficiency.

[0004] In contrast, multi-channel enzymology instruments, while capable of simultaneously detecting alanine aminotransferase (ALT) and aspartate aminotransferase (AST), seemingly solve some of the problems of single-channel instruments. However, a deeper examination of their operation reveals significant drawbacks. The operation steps are complex and cumbersome, involving multiple intricate system control steps and sample pretreatment procedures, requiring operators with high levels of professional skills and extensive experience. This undoubtedly raises the barrier to entry, hindering widespread adoption in medical and research institutions at different levels, and also making it easy for human error to lead to inaccurate test results during the complex operation process. Furthermore, from a physical construction perspective, existing enzymology analyzers are generally quite bulky, often existing as small desktop instruments. For example, patent application number 2012103045804 discloses a biochemical analysis instrument and testing method, including a main control unit and at least two independent testing units. The main control unit is interconnected with the main power control switch, the data output / input control system, and the testing units, and each testing unit includes at least a sample delivery device and a light source. The design of existing technologies limits their placement to specific locations such as laboratory benches. When faced with scenarios requiring portable testing, such as field medical rescue, bedside rapid diagnosis, and mobile medical stations at the grassroots level, they cannot meet the actual needs and greatly restrict the flexibility and timeliness of enzyme testing.

[0005] In conclusion, given the shortcomings of existing enzyme analyzers in terms of portability, diversity of detection functions, and ease of operation, there is an urgent need to develop a completely new enzyme analyzer. Summary of the Invention

[0006] This invention aims to fill this market gap by proposing an enzyme analyzer that can simultaneously detect aspartate aminotransferase (AST) and alanine aminotransferase (ALT), and is small in size and easy to carry. This opens up new paths for the development of enzyme detection technology, enabling it to better serve diverse medical and scientific research practices.

[0007] The above objectives are achieved through the following technical solutions: A portable dual-unit enzyme analyzer is characterized by comprising an encapsulated shell and its internal functional system. A light-shielding cover is installed along the edge of the functional system. The functional system includes a central control unit, a mounting base, and two detection units. Each detection unit includes a vertical guide unit, a floating lifting mechanism, a test strip placement mechanism, and a drive mechanism. The bottom of the vertical guide unit is fixedly connected to the mounting base, and a paper-pressing detection top plate is provided at its top. The central control unit is installed above the paper-pressing detection top plates of the two detection units. The floating lifting mechanism is located between the mounting base and the paper-pressing detection top plate and is slidably connected to the vertical guide unit. The drive mechanism is located on the mounting base and is drively connected to the floating lifting mechanism and electrically connected to the central control system, used to control the rising and falling of the floating lifting mechanism. The test strip placement mechanism is installed on top of the floating lifting mechanism and rises and falls together with the floating lifting mechanism, used to place the test strips.

[0008] Preferably, the vertical guide unit includes four parallel guide shafts arranged in a rectangular orientation, with the top and bottom of the guide shafts being vertically fixedly connected to the paper pressing detection top plate and the mounting base plate, respectively.

[0009] Preferably, the floating lifting mechanism includes a movable base, four floating springs, and two elastic auxiliary devices; the movable base is slidably connected to four guide shafts via four linear bearings; the two elastic auxiliary devices are located on both sides of the floating lifting mechanism, with the bottom of the elastic auxiliary devices fixedly connected to the movable base and the top hanging on the edge of the test paper placement mechanism; the four floating springs are correspondingly sleeved on the four guide shafts, and the bottom and top of the floating springs act on the movable base and the test paper placement mechanism, respectively.

[0010] Preferably, the drive mechanism includes a lead screw assembly, a first pulley, a second pulley, a synchronous belt, and a drive motor; the drive motor is located at the rear of the detection unit and is mounted on the mounting base plate via a motor mount; the lead screw assembly is mounted on the mounting base plate and passes vertically through the movable base, and is threadedly connected to the movable base; the first pulley is coaxially and fixedly connected to the shaft of the drive motor, the second pulley is mounted on the lead screw assembly, and the first pulley and the second pulley are connected by a synchronous belt drive.

[0011] Preferably, the lead screw assembly includes a lead screw body and a portal frame bracket; the portal frame bracket is fixedly connected to the mounting base plate, and the elastic auxiliary device is vertically slidably connected to the side of the portal frame bracket; the top of the lead screw body is rotatably connected to the portal frame bracket via a first bearing component, and the bottom of the lead screw body is rotatably connected to the mounting base plate via a second bearing component.

[0012] Preferably, the test strip placement mechanism includes a test strip base and a mounting plate; the mounting plate is slidably connected to four guide shafts and acts on the top of the floating lifting mechanism; a sliding groove is provided on the mounting plate, and the test strip base is slidably connected to the mounting plate in a drawer-like manner through the sliding groove, and a test strip slot is provided on the test strip base.

[0013] Preferably, heating films are embedded in the groove of the mounting plate and the top plate of the paper pressing detection, and the heating films are electrically connected to the main control unit.

[0014] Preferably, the front end of the test strip base is provided with an "eight"-shaped handle, and the "eight"-shaped handle is provided with anti-slip texture; the test strip slot of the test strip base is provided with a test strip positioning protrusion.

[0015] Based on the above-mentioned dual-portable enzyme analyzer, this technical solution proposes a method for using the dual-portable enzyme analyzer, including the following steps: S1, the user turns on the enzyme analyzer by pressing the power button on the outer casing. The functional system in the enzyme analyzer begins self-testing and warming up. After successful warm-up, the user enters the visual interaction interface. S2, users add the sample to the test strip for AST or ALT according to their testing needs; S3, open the compartment door of the packaging shell, place the test strip with the sample into the test strip placement mechanism of the corresponding detection unit, and then close the compartment door of the packaging shell; S4, the test strip is placed in the test strip placement mechanism and waits for incubation time under constant temperature conditions; S5. After incubation is complete, the drive mechanism is activated by the central control unit to input power to the floating lifting mechanism, causing the test strip placement mechanism to rise to contact the paper pressing and detection top plate; the paper pressing and detection top plate cooperates with the test strip placement mechanism to flatten the test strip. S6. After the sample and reactant on the test strip are in uniform contact, the control unit starts the measurement until the measurement is completed. S7, the central control unit starts the drive mechanism to input power to the floating lifting mechanism, so that the test paper placement mechanism descends to the initial position; S8. After the visual interaction interface indicates that the detection is complete, view the detection results on the visual interaction interface. S9, open the enclosure door, remove the test paper, reset the functional system, and finally close the enclosure door.

[0016] Preferably, placing the test strip containing the sample into the test strip placement mechanism of the corresponding detection unit includes the following steps: S31, hold the "eight" shaped handle at the front end of the test strip base with your fingers and pull the test strip base out of the mounting plate along the slide groove; S32, Align the positioning hole on the test strip with the positioning protrusion in the test strip slot to accurately place the test strip in the test strip slot of the test strip base; S33, once again grasp the "eight" shaped handle at the front end of the test strip base with your fingers, and push the test strip base containing the test strip along the slide to the mounting plate.

[0017] Compared with existing technologies, the advantages of this technical solution are: 1) Detection Function Advantages: Compared to existing single-channel enzyme instruments that cannot simultaneously detect alanine aminotransferase (ALT) and aspartate aminotransferase (AST), this technical solution's dual-channel portable enzyme analyzer is equipped with two detection units, enabling simultaneous detection of both ALT and AST. This significantly improves detection efficiency, avoiding the time wastage, increased sample volume, and operational errors associated with multiple tests. Compared to the operational complexity of existing multi-channel enzyme instruments, the analyzer in this technical solution has a relatively simple operation procedure, reducing the skill requirements for operators and minimizing deviations in test results due to improper operation.

[0018] 2) Portability Advantage: Compared to most enzyme analyzers currently on the market, which are bulky and can only be used in specific locations, this technical solution's dual-unit portable enzyme analyzer is ingeniously designed, compact in size, and equipped with a sealed shell for easy carrying. It can easily meet the needs of various scenarios, including field medical rescue, bedside rapid diagnosis, and mobile medical stations at the grassroots level, greatly improving the flexibility and timeliness of enzyme testing.

[0019] 3) Structural Design Advantages: In terms of structure, this technical solution employs a series of unique designs. For example, the four guide shafts of the vertical guide unit are arranged in a rectangular orientation, providing stable support for the entire detection unit; the floating lifting mechanism, through the cooperation of a movable base, floating springs, and elastic auxiliary devices, enables the test strip placement mechanism to move smoothly up and down; the drive mechanism uses a screw assembly, pulleys, and synchronous belt transmission method, resulting in a compact and reasonable structure and efficient power transmission. These designs not only ensure the stable operation of the analyzer but also reduce the size of the instrument to a certain extent.

[0020] 4) Ease of Use: The dual-unit portable enzyme analyzer of this invention is simple and easy to operate. Users only need to follow the steps of powering on, preparing samples, placing test strips, waiting for incubation, performing the test, viewing the results, and cleaning / resetting. It has self-test and preheating functions after powering on to ensure the instrument is in good working order; the visual interface is intuitive and clear, facilitating user operation and result viewing; the test strip placement mechanism is reasonably designed, with an "8"-shaped handle and anti-slip texture for easy placement of test strips, and a test strip positioning protrusion to ensure accurate placement. These features demonstrate the advantages of this invention in terms of ease of use. Attached Figure Description

[0021] Figure 1 This is a schematic diagram of the internal structure of a dual-portable enzyme analyzer. Figure 2 This is a schematic diagram of a partial internal structure of a dual-channel portable enzyme analyzer. Figure 3 This is a schematic diagram of the internal partial frontal structure of a dual-channel portable enzyme analyzer.

[0022] In the picture: 1. Encapsulation housing; 2. Light shield; 3. Paper pressure detection top plate; 4. Mounting base plate; 5. Vertical guide unit; 5.1. Guide shaft; 6. Floating lifting mechanism; 6.1. Movable base; 6.2. Linear bearing; 6.3. Floating spring; 6.4. Elastic auxiliary device; 7. Drive mechanism; 7.1. Lead screw assembly; 7.11. Lead screw body; 7.12. Portal bracket; 7.13. First bearing component; 7.14. Second bearing component; 7.2. First pulley; 7 7.3 Second pulley; 7.4 Synchronous belt; 7.5 Drive motor; 7.6 Motor mount; 8 Test strip placement mechanism; 8.1 Mounting plate; 8.2 Slide groove; 8.3 Test strip base; 8.4 Test strip slot; 8.5 Figure-eight shaped handle; 8.6 Anti-slip texture; 8.7 Paper positioning protrusion; 9 Heating film; 10 Test strip; 11 Main control unit; 11.1 Main board PCBA; 11.2 PD detection board; 11.3 Adapter board PCBA. Detailed Implementation

[0023] To make the objectives, technical solutions, and advantages of the embodiments of the present invention clearer, the technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. It should not be construed that the present invention is limited to the following examples. Without departing from the concept of the present invention, all modifications and improvements of the present invention in this field should be included within the protection scope of the claims of the present invention.

[0024] Unless otherwise defined, the technical or scientific terms used in this disclosure shall have the ordinary meaning as understood by one of ordinary skill in the art to which this disclosure pertains. Words such as “or” and “comprising” as used in this disclosure mean that an element or object preceding that word encompasses the elements or objects listed following that word and their equivalents, but do not exclude other elements or objects.

[0025] Example 1 This embodiment discloses a dual-portable enzyme analyzer, which is a preferred embodiment of the present invention. It features a sophisticated structural design and practical functionality. Figure 1 As shown, the analyzer includes a housing 1 and its internal functional systems. A light shield 2 is installed along the edge of the functional systems. The light shield 2 effectively prevents external light from interfering with the detection process, ensuring the accuracy of the detection results. The housing 1 not only protects the internal functional systems from external physical damage and dust corrosion, but its reasonable shape also makes it easy for users to carry, providing a safe and convenient external environment for the entire analyzer. The internal functional systems are the core of the analyzer, including a central control unit 11, a mounting base 4, and two detection units.

[0026] The two detection units are key components for realizing the enzymatic analysis function. The two units have clearly defined functions: one is specifically for detecting aspartate aminotransferase (AST), and the other for detecting alanine aminotransferase (ALT). This design allows the analyzer to simultaneously detect two important transaminases, greatly improving detection efficiency. Each detection unit includes a vertical guide unit 5, a floating lifting mechanism 6, a test strip placement mechanism 8, and a drive mechanism 7.

[0027] The bottom of the vertical guide unit 5 is securely connected to the mounting base plate 4, providing a stable foundation support for the other components of the entire detection unit. The paper-pressing detection top plate 3 set at its top plays a crucial role in the detection process. It works in conjunction with the test paper placement mechanism 8 to press the test paper 10, ensuring that the enzymatic reaction on the test paper 10 is fully carried out, thereby assisting in the detection of the test paper 10.

[0028] The central control unit 11 is installed above the paper pressing detection top plate 3 of the two detection units. On the one hand, it is responsible for collecting data from the test paper 10 on the detection unit, analyzing and presenting it so that users can intuitively obtain the test results; on the other hand, it coordinates and controls various components to ensure that the entire detection process proceeds in an orderly manner.

[0029] The floating lifting mechanism 6 is located between the mounting base plate 4 and the paper pressing and detection top plate 3, and is slidably connected to the vertical guide unit 5. This sliding connection allows the floating lifting mechanism 6 to move stably up and down under the guidance of the vertical guide unit 5. The purpose of its movement is to achieve contact and separation between the test paper placement mechanism 8 and the paper pressing and detection top plate 3, thereby completing the detection operation of the test paper 10 by the central control unit 11.

[0030] The drive mechanism 7 is mounted on the mounting base plate 4. It is connected to the floating lifting mechanism 6 via a transmission connection and is also electrically connected to the central control system. When the central control unit 11 issues a command, the drive mechanism 7 can control the floating lifting mechanism 6 to rise and fall according to the command requirements.

[0031] The test strip placement mechanism 8 is installed on top of the floating lifting mechanism 6, and it rises and falls together with the floating lifting mechanism 6. Its main function is to place the test strip 10. During the detection process, the test strip 10 is placed on this mechanism, and as the floating lifting mechanism 6 moves, it cooperates with the paper pressing detection top plate 3 to complete the enzyme analysis detection of the sample. Specifically: before the detection begins, after the test strip 10 is placed in the test strip placement mechanism 8, the central control unit 11 issues a rising command, and the drive mechanism 7 drives the floating lifting mechanism 6 to rise, so that the test strip 10 on the test strip placement mechanism 8 is close to the paper pressing detection top plate 3; after the enzyme reaction of the test strip 10 is complete, and the central control unit 11 has completed the data acquisition on the test strip 10, the central control unit 11 issues a descending command, and the drive mechanism 7 drives the floating lifting mechanism 6 to descend, so that the test strip placement mechanism 8 separates from the paper pressing detection top plate 3.

[0032] In summary, this dual-unit portable enzyme analyzer achieves efficient and accurate enzyme detection through the close cooperation and synergistic operation of its various components. The two detection units can operate independently, greatly improving the convenience of detection and providing a powerful tool for testing in related fields.

[0033] Example 2 This embodiment discloses a dual-portable enzyme analyzer. As a preferred embodiment of the present invention, based on Embodiment 1, its vertical guide unit 5 includes four parallel guide shafts 5.1 arranged in a rectangular orientation. The top and bottom of the guide shafts 5.1 are vertically and fixedly connected to the paper pressing detection top plate 3 and the mounting base plate 4, respectively. This structure provides a stable foundation support for other components of the entire detection unit.

[0034] Based on this, the floating lifting mechanism 6 includes a movable base 6.1, four floating springs 6.3, and two elastic auxiliary devices 6.4. The movable base 6.1 is slidably connected to four guide shafts 5.1 via four linear bearings 6.2, allowing the movable base 6.1 to move smoothly up and down under the guidance of the guide shafts 5.1. The bottom of the elastic auxiliary device 6.4 is fixedly connected to the movable base 6.1; the top has a hook structure and hangs on the edge of the test paper placement mechanism 8. The elastic auxiliary device 6.4 is a plastic spring, which assists in pulling down the test paper placement mechanism 8 and acts as a buffer, further ensuring the stability of the movement of the test paper placement mechanism 8. The four floating springs 6.3 are correspondingly sleeved on the four guide shafts 5.1, and the bottom and top of the floating springs 6.3 act on the movable base 6.1 and the test paper placement mechanism 8 respectively. The floating springs 6.3 can provide a certain elastic force, which helps the test paper placement mechanism 8 to better contact and separate from the paper pressing detection top plate 3 during the detection process.

[0035] In this technical solution: when the elastic auxiliary device 6.4 descends together with the movable base 6.1, the elastic auxiliary device 6.4 engages with the edge of the test strip placement mechanism 8, pulling the test strip placement mechanism 8 down together; when the elastic auxiliary device 6.4 rises together with the movable base 6.1, the elastic auxiliary device 6.4 moves upward to create a tendency to disengage from the test strip placement mechanism 8, and the test strip placement mechanism 8 rises under the support of the floating spring 6.3. Throughout the process, the force exerted by the elastic auxiliary device 6.4 on the test strip placement mechanism 8 is downward, and the force exerted by the floating spring 6.3 on the test strip placement mechanism 8 is upward, making the test strip placement mechanism 8 stable and without shaking. The floating lifting mechanism, through its unique design, reduces the error impact from various components and the test strip, adapts to the state of the test strip, and overall reduces errors and costs while improving detection accuracy.

[0036] Example 3 This embodiment discloses a dual-unit portable enzyme analyzer. As a preferred embodiment of the present invention, based on Embodiment 2, its drive mechanism 7 includes a lead screw assembly 7.1, a first pulley 7.2, a second pulley 7.3, a synchronous belt 7.4, and a drive motor 7.5. The drive motor 7.5 is located at the rear of the detection unit and is mounted on the mounting base 4 via a motor mount 7.6, providing power to the entire drive mechanism 7. The lead screw assembly 7.1 includes a lead screw body 7.11 and a portal frame 7.12. The portal frame 7.12 is fixedly connected to the mounting base 4, and the elastic auxiliary device 6.4 is vertically slidably connected to the side of the portal frame 7.12. The portal frame 7.12 provides certain support for the elastic auxiliary device 6.4, which further optimizes the motion stability of the floating lifting mechanism 6. The top of the lead screw body 7.11 is rotatably connected to the portal frame 7.12 via the first bearing 7.13, and the bottom of the lead screw body 7.11 is rotatably connected to the mounting base 4 via the second bearing 7.14. This design allows the lead screw body 7.11 to rotate smoothly. The lead screw assembly 7.1 is mounted on the mounting base 4 and vertically passes through the movable base 6.1, being threadedly connected to it. When the lead screw assembly 7.1 rotates, it can drive the movable base 6.1 to move up and down along the lead screw direction. The first pulley 7.2 is coaxially fixedly connected to the shaft of the drive motor 7.5, and the second pulley 7.3 is mounted on the lead screw assembly 7.1. The first pulley 7.2 and the second pulley 7.3 are connected by a synchronous belt 7.4. This design makes the layout of the various components of the drive mechanism 7 compact and reasonable, achieving efficient power transmission and motion control within a limited space, further highlighting the compactness of the structural design of this technical solution.

[0037] Example 4 This embodiment discloses a dual-portable enzyme analyzer. As a preferred embodiment of the present invention, based on embodiments 2, 3, or 4, the test strip placement mechanism 8 includes a test strip base 8.3 and a mounting plate 8.1. The mounting plate 8.1 is slidably connected to four guide shafts 5.1 and acts on the top of the floating lifting mechanism 6, thus allowing it to rise and fall together with the floating lifting mechanism 6. A groove 8.2 is provided on the mounting plate 8.1, and the test strip base 8.3 is slidably connected to the mounting plate 8.1 in a drawer-like manner through the groove 8.2. This connection method facilitates the user's replacement and placement of test strips. A test strip slot 8.4 is provided on the test strip base 8.3 for accurately placing the test strip 10.

[0038] Furthermore, heating films 9 are embedded in the groove 8.2 of the mounting plate 8.1 and on the paper pressing detection top plate 3, respectively, and the heating films 9 are electrically connected to the main control unit 11. The main control unit 11 can control the operation of the heating films 9 according to the detection requirements, providing a suitable temperature environment for the test paper 10, ensuring that the enzymatic reaction can be carried out under optimal conditions, and improving the accuracy of the detection.

[0039] Furthermore, the front end of the test strip base 8.3 is equipped with an "8"-shaped handle 8.5. The design of the "8"-shaped handle 8.5 is ergonomic and convenient for users to operate. The handle is also equipped with anti-slip textures 8.6, which effectively increase friction and prevent slippage when removing or inserting the test strip base 8.3. A test strip positioning protrusion 8.7 is provided in the test strip slot 8.4 of the test strip base 8.3, which can accurately fix the position of the test strip 10, ensuring that the test strip will not shift during the test, thereby improving the reliability of the test results.

[0040] Example 5 This embodiment discloses a dual-unit portable enzyme analyzer. As a preferred embodiment of the present invention, based on embodiments 1, 2, 3 or 4, its main control unit 11 serves as the core hub of the dual-unit portable enzyme analyzer. Its composition structure is precise and complex, and it plays a crucial role in the operation of the entire analyzer.

[0041] In terms of its composition, the main control unit 11 mainly includes a motherboard PCBA11.1, two PD detection boards 11.2, and an adapter board PCBA11.3. Among them, the motherboard PCBA11.1 is the core component of the main control unit 11 and is the "central processing unit" of the entire analyzer, responsible for coordinating and processing various types of data and issuing control commands.

[0042] Two PD detection plates 11.2 are respectively installed on the top of the paper-pressing detection top plate 3 of the detection unit, and they are key components for data acquisition. The PD detection plates 11.2 are mainly used to detect changes in optical signals on the test strip 10, which are closely related to the progress and results of the enzymatic reaction. Through accurate detection of these signals, the PD detection plates 11.2 can convert them into electrical signals, providing raw data support for subsequent data analysis.

[0043] The PD detection board 11.2 is mounted on the adapter board PCBA11.3 and is electrically connected to the main board PCBA11.1 through the adapter board PCBA11.3. The adapter board PCBA11.3 acts as a bridge here. On the one hand, it ensures a stable electrical connection between the PD detection board 11.2 and the main board PCBA11.1. On the other hand, it performs preliminary processing and transmission of the signals from the PD detection board 11.2, so that the signals can be received and processed by the main board PCBA11.1 in an appropriate form.

[0044] In terms of its working principle, once the detection process is initiated, an enzymatic reaction occurs on the test strip 10, generating corresponding changes in optical signals. The PD detection board 11.2 captures these signals in real time and converts them into electrical signals. These electrical signals are transmitted to the main board PCBA11.1 via the adapter board PCBA11.3. Upon receiving the signals, the main board PCBA11.1 performs in-depth analysis and processing of the data based on its built-in algorithms and programs. For example, based on factors such as signal intensity and trends, it calculates the levels of aspartate aminotransferase (AST) and alanine aminotransferase (ALT), and presents these analytical results, possibly in a visually intuitive format such as numbers or charts, to the user.

[0045] Meanwhile, the mainboard PCBA11.1 is also responsible for coordinating and controlling the various components of the analyzer. Before testing, it sends a command to the drive mechanism 7 to control the floating lifting mechanism 6 to rise, so that the test strip 10 on the test strip placement mechanism 8 is close to the paper pressing detection top plate 3. During the testing process, it controls the heating film 9 on the mounting plate 8.1 slide groove 8.2 and the paper pressing detection top plate 3 to work according to the testing requirements, so as to provide a suitable temperature environment for the test strip 10. After the testing is completed, it sends a command to the drive mechanism 7 to drive the floating lifting mechanism 6 to descend, so that the test strip placement mechanism 8 is separated from the paper pressing detection top plate 3.

[0046] In summary, through the coordinated operation of the main board PCBA11.1, the PD detection board 11.2, and the adapter board PCBA11.3, the main control unit 11 realizes the acquisition, analysis, and presentation of detection data, as well as the precise control of each component, ensuring that the dual-portable enzyme analyzer can complete enzyme detection tasks efficiently and accurately.

[0047] Example 6 This embodiment discloses a method for using any one of the dual-portable enzyme analyzers in Examples 1 to 5. As a preferred embodiment of the present invention, it includes the following steps: Power-on and Preparation: The user first locates the power button on the outer casing 1 and presses it to power on the enzyme analyzer. At this time, the analyzer's internal systems quickly start up, beginning self-testing and warm-up. During the self-test, the system automatically checks whether each component is operating normally, ensuring the analyzer is in good working condition. Warm-up is to allow the detection environment to reach a suitable temperature, ensuring the accuracy of the test results. After successful warm-up, the analyzer enters the visual interactive interface, which is intuitive and clear, facilitating subsequent operations.

[0048] Sample preparation: Users should specify whether they need to test for aspartate aminotransferase (AST) or alanine aminotransferase (ALT), and then carefully add the collected sample to the corresponding test strip 10. When adding the sample, it is important to control the amount to avoid affecting the test results if too much or too little sample is added.

[0049] Placing the test strip: Open the compartment door of the packaging shell 1 to reveal the internal detection unit. Open the corresponding test strip placement mechanism 8, which is rationally designed and easy to operate. Carefully place the test strip 10 containing the sample into the test strip placement mechanism 8, ensuring correct placement. Then close the test strip placement mechanism 8, and finally close the compartment door of the packaging shell 1 to prevent external factors from interfering with the detection process. The process of smoothly placing the test strip 10 containing the sample into the test strip placement mechanism 8 includes the following steps: holding the "V"-shaped handle 8.5 at the front end of the test strip base 8.3 with your fingers, and pulling the test strip base 8.3 out of the mounting plate 8.1 along the slide groove 8.2; aligning the positioning hole on the test strip 10 with the test strip positioning protrusion 8.7 in the test strip slot 8.4, so as to accurately place the test strip 10 in the test strip slot 8.4 of the test strip base 8.3; again holding the "V"-shaped handle 8.5 at the front end of the test strip base 8.3 with your fingers, and pushing the test strip base 8.3 containing the test strip 10 onto the mounting plate 8.1 along the slide groove 8.2.

[0050] Incubation Waiting: After the test strip 10 is placed into the test strip placement mechanism 8, it will be incubated under constant temperature conditions. During the incubation process, the reactants in the test strip begin to react with the sample, preparing for subsequent testing. Users only need to wait patiently for the incubation time to end; no other operations are required during this period.

[0051] Detection Process: After incubation, the central control unit 11 plays its core role, activating the drive mechanism 7. The drive mechanism 7 inputs power to the floating lifting mechanism 6, causing the test strip placement mechanism 8 to rise smoothly until it contacts the paper-pressing detection top plate 3. The paper-pressing detection top plate 3 and the test strip placement mechanism 8 work closely together to flatten the test strip 10, ensuring full contact between the test strip 10 and the detection equipment. Once the sample and reactant on the test strip 10 are in uniform contact, the central control unit 11 begins the measurement process. During the measurement, the central control unit 11 collects and analyzes the detection data in real time.

[0052] Test Completed: After measurement, the central control unit 11 restarts the drive mechanism 7, causing the floating lifting mechanism 6 to lower the test strip placement mechanism 8 to its initial position. At this time, the visual interface will indicate that the test is complete, and the user can view the detailed test results on this interface. The test results are presented in an intuitive way, such as numbers and charts, for easy user understanding.

[0053] Cleaning and Reset: After reviewing the test results, open the compartment door of the enclosure 1 and the corresponding test strip placement mechanism 8, and remove the test strip 10. Used test strips should be disposed of properly to avoid environmental contamination. After removing the test strip, reset the functional system to ensure the analyzer returns to its initial state for future use. Finally, close the compartment door of the enclosure 1 to complete the entire testing process.

Claims

1. A dual-portable enzymatic analyzer, characterized in that: It includes a packaged outer shell (1) and its internal functional system. A light shield (2) is installed along the edge of the outer side of the functional system. The functional system includes a central control unit (11), a mounting base plate (4), and two detection units. The detection units include a vertical guide unit (5), a floating lifting mechanism (6), a test paper placement mechanism (8), and a drive mechanism (7). The vertical guide unit (5) includes four parallel guide shafts (5.1) arranged in a rectangular orientation. The bottom of the guide shaft (5.1) is vertically fixed to the mounting base plate (4), and the top of the guide shaft (5.1) is vertically fixed to the paper pressing detection top plate (3). The main control unit (11) is installed above the paper pressing detection top plates (3) of the two detection units. The floating lifting mechanism (6) is located between the mounting base plate (4) and the paper pressing detection top plate (3), and includes a movable base (6.1), four floating springs (6.3) and two elastic auxiliary devices (6.4). The movable base (6.1) is slidably connected to the four guide shafts (5.1) through four linear bearings (6.2); four floating springs (6.3) are fitted on the four guide shafts (5.1) one by one, and the bottom of the floating springs (6.3) acts on the movable base (6.1); The test strip placement mechanism (8) is slidably connected to four guide shafts (5.1), and its bottom acts on the top of the floating spring (6.3), rising and falling together with the floating lifting mechanism (6) to place the test strip (10); the two elastic auxiliary devices (6.4) are respectively located on both sides of the floating lifting mechanism (6), and the bottom of the elastic auxiliary device (6.4) is fixedly connected to the movable base (6.1), and the top is hung on the edge of the test strip placement mechanism (8); The drive mechanism (7) is mounted on the mounting base plate (4) and is connected to the floating lifting mechanism (6) via transmission and to the main control unit (11) via electrical connection, for controlling the floating lifting mechanism (6) to rise and fall.

2. The dual-portable enzyme analyzer as described in claim 1, characterized in that: The drive mechanism (7) includes a lead screw assembly (7.1), a first pulley (7.2), a second pulley (7.3), a synchronous belt (7.4), and a drive motor (7.5); the drive motor (7.5) is located behind the detection unit and is mounted on the mounting base (4) via a motor mount (7.6); the lead screw assembly (7.1) is mounted on the mounting base (4) and vertically passes through the movable base (6.1), and is threadedly connected to the movable base (6.1); the first pulley (7.2) is coaxially fixedly connected to the shaft of the drive motor (7.5), and the second pulley (7.3) is mounted on the lead screw assembly (7.1). On 7.1), the first pulley (7.2) and the second pulley (7.3) are connected by a synchronous belt (7.4).

3. The dual-portable enzyme analyzer as described in claim 2, characterized in that: The lead screw assembly (7.1) includes a lead screw body (7.11) and a portal frame (7.12); the portal frame (7.12) is fixedly connected to the mounting base plate (4), and the elastic auxiliary device (6.4) is vertically slidably connected to the side of the portal frame (7.12); the top of the lead screw body (7.11) is rotatably connected to the portal frame (7.12) through a first bearing (7.13), and the bottom of the lead screw body (7.11) is rotatably connected to the mounting base plate (4) through a second bearing (7.14).

4. The dual-portable enzymatic analyzer as described in claim 1, characterized in that: The test strip placement mechanism (8) includes a test strip base (8.3) and a mounting plate (8.1); the mounting plate (8.1) is slidably connected to four guide shafts (5.1) and acts on the top of the floating lifting mechanism (6); a sliding groove (8.2) is provided on the mounting plate (8.1), the test strip base (8.3) is slidably connected to the mounting plate (8.1) in a drawer-like manner through the sliding groove (8.2), and a test strip slot (8.4) is provided on the test strip base (8.3).

5. The dual-portable enzyme analyzer as described in claim 4, characterized in that: Heating films (9) are embedded in the groove (8.2) of the mounting plate (8.1) and on the paper pressing detection top plate (3), and the heating films (9) are electrically connected to the main control unit (11).

6. The dual-portable enzyme analyzer as described in claim 4, characterized in that: The front end of the test paper base (8.3) is provided with an "eight" shaped handle (8.5), and the "eight" shaped handle (8.5) is provided with anti-slip texture (8.6); the test paper slot (8.4) of the test paper base (8.3) is provided with a test paper positioning protrusion (8.7).

7. A method of using a dual-portable enzyme analyzer, characterized in that, The following steps are performed using a dual-portable enzyme analyzer as described in any one of claims 1-6: S1, the user turns on the enzyme analyzer by pressing the power button on the outer casing (1). The functional system in the enzyme analyzer begins self-testing and preheating. After successful preheating, the user enters the visual interaction interface. S2, according to the testing requirements, the user adds the sample to the test strip (10) for aspartate aminotransferase or alanine aminotransferase; S3, open the compartment door of the packaging shell (1), put the test strip (10) with the sample into the test strip placement mechanism (8) of the corresponding detection unit, and then close the compartment door of the packaging shell (1); S4, the test strip (10) is placed in the test strip placement mechanism (8) and waits for incubation time under constant temperature conditions; S5, after incubation is completed, the drive mechanism (7) is started by the main control unit (11) to input power to the floating lifting mechanism (6), so that the test paper placement mechanism (8) rises to contact the paper pressing detection top plate (3); the paper pressing detection top plate (3) and the test paper placement mechanism (8) cooperate to press the test paper (10) flat; S6, after the sample on the test paper (10) and the reactant are in uniform contact, the control unit (11) starts the measurement until the measurement is completed; S7, the central control unit (11) starts the drive mechanism (7) to input power to the floating lifting mechanism (6), so that the test paper placement mechanism (8) descends to the initial position; S8. After the visual interaction interface indicates that the detection is complete, view the detection results on the visual interaction interface. S9, open the door of the package shell (1), take out the test paper (10), reset the functional system, and finally close the door of the package shell (1).

8. The method of using the dual-portable enzyme analyzer as described in claim 7, characterized in that, In step S3, placing the test strip (10) containing the sample into the test strip placement mechanism (8) of the corresponding detection unit includes the following steps: S31, hold the "8"-shaped handle (8.5) at the front end of the test strip base (8.3) with your fingers and pull the test strip base (8.3) out of the mounting plate (8.1) along the slide (8.2); S32, align the positioning hole on the test strip (10) with the test strip positioning protrusion (8.7) in the test strip slot (8.4) so ​​as to accurately place the test strip (10) in the test strip slot (8.4) of the test strip base (8.3); S33, hold the "eight" shaped handle (8.5) at the front end of the test strip base (8.3) with your fingers again, and push the test strip base (8.3) containing the test strip (10) onto the mounting plate (8.1) along the slide (8.2).

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