一种以橙皮甙为原料制备三叶苷的方法
By using hesperidin as a raw material, hydrolyzing it to remove rhamnose, reacting it with p-hydroxybenzaldehyde, and then reducing it, high-purity trifolin was prepared, solving the problems of high raw material source and cost of trifolin and making it suitable for industrial production.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- SHAANXI JIAHE PHYTOCHEM CO LTD
- Filing Date
- 2025-03-11
- Publication Date
- 2026-07-17
AI Technical Summary
In existing technologies, the limited availability and high cost of raw materials for trifolin result in excessively high preparation costs, which is detrimental to market promotion.
Using hesperidin with a content greater than 90% as raw material, intermediate 1 was obtained by hydrolyzing rhamnose to obtain intermediate 1, which was then reacted with p-hydroxybenzaldehyde under alkaline conditions to obtain intermediate 2. Finally, a reduction reaction was carried out and the product was purified to obtain trifolin.
This paper presents a method for preparing trifolin with abundant raw materials, low cost, and simple operation, which is suitable for industrial production. The intermediate has high purity and high conversion rate, and solves the problems of raw material source and cost.
Smart Images
Figure CN120192355B_ABST