靶向补体成分C3基因的寡核苷酸及其用途
By using oligonucleotides that target the complement component C3 gene with double-stranded RNA, the problems of time-consuming and costly existing treatment methods have been solved, achieving effective inhibition of complement component C3 and providing a safe and long-lasting treatment option.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- ANLONG BIOPHARMACEUTICAL CO LTD
- Filing Date
- 2025-02-09
- Publication Date
- 2026-07-17
AI Technical Summary
Existing treatments for complement component C3-related diseases are time-consuming, invasive, and costly, and there is a lack of effective alternatives and combination therapies.
Using double-stranded RNA (dsRNA) as oligonucleotides, the complement component C3 gene was targeted through RNA interference (RNAi) to guide sequence-specific degradation of mRNA, and oligonucleotides or their pharmaceutically acceptable salts were developed to inhibit the expression of complement component C3.
It effectively inhibits complement component C3, reduces the C3 content in the body, and provides a safe and long-lasting treatment option suitable for a variety of complement component C3-related diseases.
Smart Images

Figure CN120202299B_ABST