Multi-channel biochemical analysis detector and control method

Abstract

The present disclosure relates to a multi-channel biochemical analysis detector and a control method, the multi-channel biochemical analysis detector comprising a fixing unit for fixing a biochemical sensor array signal interface, the fixing unit comprising a socket, a fixing plane, an in-place detection module, a connecting module, a driving module and a control module, the in-place detection module detects that the signal interface is inserted into the socket, generates an in-place signal and transmits the in-place signal to the control module, the control module controls the driving module to move the connecting module in response to the in-place signal until the connecting module is in contact with the signal interface to form an electrical connection and the signal interface is fixed on the fixing plane. Thus, the signal interface of the biochemical sensor array is fixed on the fixing plane in an electrically controlled manner, so that the biochemical sensor array does not displace during the detection process, which is conducive to improving the accuracy and stability of the signal; at the same time, the electrical connection between the connecting module and the signal interface also realizes the input of the signal of the biochemical sensor array into the multi-channel biochemical analysis detector.

Description

Technical Field

[0001] This disclosure relates to the field of biosensor technology, and in particular to a multi-channel biochemical analyzer and its control method. Background Technology

[0002] In recent years, flexible sensors have been widely used in robotic tactile sensing, wearable medical devices and industrial automation due to their advantages such as high flexibility, lightweight and customizable wiring.

[0003] In related technologies, due to the deformable nature of flexible sensors, traditional flexible sensor detection devices struggle to fix the absolute position of the flexible sensor, preventing its application in scenarios requiring precise sensor position information. Furthermore, the circuitry of flexible sensors is easily affected by their deformation characteristics, leading to signal distortion and difficulty in controlling signal accuracy. Summary of the Invention

[0004] To address the aforementioned technical problems, this disclosure provides a multi-channel biochemical analyzer and its control method.

[0005] On one hand, this disclosure provides a multi-channel biochemical analyzer, which is used to detect a biochemical sensor array. The biochemical sensor array includes multiple biochemical sensors arranged in an array and a signal interface connected to the biochemical sensors. The multi-channel biochemical analyzer includes a fixing unit, which is used to fix the signal interface of the biochemical sensor array.

[0006] The fixing unit includes: a socket, a fixing plane, an in-situ detection module, a connection module, a drive module, and a control module;

[0007] The in-situ detection module, the drive module, and the connection module are all electrically connected to the control module; the connection module is connected to the drive module.

[0008] The control module is used to control the movement of the drive module in response to the presence signal transmitted by the presence detection module. The drive module drives the connection module to move until the connection module contacts the signal interface and fixes the signal interface on the fixed plane. The presence signal is generated by the presence detection module when it detects that the signal interface is inserted into the socket.

[0009] On the other hand, this disclosure also provides a control method for a multi-channel biochemical analyzer, wherein the multi-channel biochemical analyzer is used to detect a biochemical sensor array, the biochemical sensor array including multiple biochemical sensors arranged in an array and a signal interface connected to the biochemical sensors; the multi-channel biochemical analyzer includes a fixing unit, the fixing unit being used to fix the signal interface of the biochemical sensor array;

[0010] The fixing unit includes: a socket, a fixing plane, an in-situ detection module, a connection module, a drive module, and a control module;

[0011] The in-situ detection module, the drive module, and the connection module are all electrically connected to the control module; the connection module is fixed to the drive module.

[0012] The control method includes:

[0013] The control module responds to the presence signal transmitted by the presence detection module and controls the drive module to move. The drive module drives the connection module to move until the connection module contacts the signal interface and fixes the signal interface on the fixed plane. The presence signal is generated by the presence detection module when it detects that the signal interface is inserted into the socket.

[0014] The technical solution provided in this disclosure has the following advantages compared with the prior art:

[0015] This disclosure provides a multi-channel biochemical analyzer and its control method. The multi-channel biochemical analyzer is used to detect biochemical sensor arrays. It includes a fixing unit for fixing the signal interface of the biochemical sensor array. The fixing unit includes a socket, a fixing plane, an in-situ detection module, a connection module, a drive module, and a control module. When the in-situ detection module detects that the signal interface is inserted into the socket, it generates an in-situ signal and transmits it to the control module. The control module responds to the in-situ signal by controlling the drive module to move the connection module until it contacts the signal interface to form an electrical connection, thus fixing the signal interface to the fixing plane. Based on this, fixing the signal interface of the biochemical sensor array to the fixing plane using electric control prevents displacement of the biochemical sensor array during detection, which is beneficial for improving signal accuracy and stability. Simultaneously, the electrical connection between the connection module and the signal interface also enables the input of the signal from the biochemical sensor array into the multi-channel biochemical analyzer. Attached Figure Description

[0016] The accompanying drawings, which are incorporated in and form a part of this specification, illustrate embodiments consistent with this disclosure and, together with the description, serve to explain the principles of this disclosure.

[0017] To more clearly illustrate the technical solutions in the embodiments of this disclosure or the prior art, the accompanying drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, for those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0018] Figure 1 This is a schematic diagram of the structure of a biochemical sensing array provided in an embodiment of the present disclosure;

[0019] Figure 2 This is a schematic diagram of the structure of a multi-channel biochemical analyzer provided in an embodiment of the present disclosure;

[0020] Figure 3 This is a schematic diagram of another multi-channel biochemical analyzer provided in an embodiment of the present disclosure;

[0021] Figure 4 This is a schematic diagram of the structure of a fixed unit provided in an embodiment of the present disclosure;

[0022] Figure 5 This is a schematic diagram of the structure of another multi-channel biochemical analyzer provided in the embodiments of this disclosure;

[0023] Figure 6 This is a schematic diagram of the structure of a signal processing module provided in an embodiment of the present disclosure;

[0024] Figure 7 This is a schematic diagram of a constant current source circuit provided in an embodiment of the present disclosure;

[0025] Figure 8 A schematic flowchart illustrating a control method for a multi-channel biochemical analyzer provided in this embodiment of the present disclosure;

[0026] Figure 9 A flowchart illustrating another control method for a multi-channel biochemical analyzer provided in this embodiment of the present disclosure;

[0027] Figure 10 This is a flowchart illustrating another control method for a multi-channel biochemical analyzer provided in this embodiment of the present disclosure. Detailed Implementation

[0028] To better understand the above-mentioned objectives, features, and advantages of this disclosure, the solutions disclosed herein will be further described below. It should be noted that, unless otherwise specified, the embodiments and features described herein can be combined with each other.

[0029] Numerous specific details are set forth in the following description in order to provide a full understanding of this disclosure, but this disclosure may also be implemented in other ways different from those described herein; obviously, the embodiments in the specification are only some, and not all, of the embodiments of this disclosure.

[0030] The multi-channel biochemical analyzer and control method provided in this disclosure are described below with reference to the accompanying drawings.

[0031] In some embodiments, such as Figure 1 As shown, the biochemical sensor array 1 includes multiple biochemical sensors 11 arranged in an array and a signal interface 12 connected to the biochemical sensors.

[0032] Among them, the biochemical sensor array 1 is a flexible sensor, which includes multiple biochemical sensors 11, and can simultaneously and specifically bind to multiple groups of biomolecules to be tested, so as to achieve batch detection and improve detection efficiency.

[0033] The multi-channel biochemical analyzer provided in this embodiment is used to measure the signal of the biochemical sensor array 1. The signal interface 12 of the biochemical sensor array 1 is inserted into the socket of the multi-channel biochemical analyzer, establishing an electrical connection between the multi-channel biochemical analyzer and the signal interface 12. The signal of the biochemical sensor array 1 is measured, and the target detection index is finally output. For example, the target detection index includes at least the resistance value.

[0034] like Figure 2-3 As shown, the multi-channel biochemical analyzer 2 includes a fixed unit housing structure, which houses other components of the multi-channel biochemical analyzer 2, such as a fixed unit, a control unit, a signal acquisition unit, a signal path selection unit, a signal processing unit, a communication unit, a display management unit, a power management unit, a storage unit, and an interaction unit.

[0035] The multi-channel biochemical analyzer 2 includes a fixing unit for fixing the signal interface 12 of the biochemical sensor array 1. For example... Figure 3 or Figure 4 As shown, the fixing unit includes a socket 21, a fixing plane, an in-situ detection module 22, a connection module 23, a drive module 24, and a control module 25; the in-situ detection module 22, the drive module 24, and the connection module 23 are all electrically connected to the control module 25.

[0036] The socket 21 is disposed on the housing mechanism and extends through the housing mechanism in the thickness direction. The socket 21 is used to allow the signal interface 12 of the biochemical sensor array 1 to be inserted.

[0037] The presence detection module 22 is used to detect that the signal interface 12 has been inserted into the socket 21, generate a presence signal, and transmit the presence signal to the control module 25. Exemplarily, the presence detection module 22 includes a photoelectric presence sensor.

[0038] The fixed plane is used to place the signal interface 12 of the biochemical sensor array 1.

[0039] The connection module 23 serves both as a clamping mechanism for fixing the signal interface 12 and as a signal input terminal for the multi-channel biochemical analyzer 2, connecting the signal from the biochemical sensor array 1 to the multi-channel biochemical analyzer 2. The connection module 23 is connected to the drive module 24 and moves under the power of the drive module 24, contacting the signal interface 12 to form an electrical connection, thus enabling the input of the signal from the biochemical sensor array 1 to the multi-channel biochemical analyzer 2. Simultaneously, it presses the signal interface 12 firmly onto the fixed plane, fixing the signal interface 12 and preventing displacement of the biochemical sensor array 1 during subsequent detection, which helps improve the accuracy and stability of the signal.

[0040] The control module 25 includes a microcontroller unit (MCU) storing a control program. In response to the presence signal transmitted by the presence detection module 22, the control module 25 determines that the signal interface 12 has been inserted into the socket 21 (or is located on the fixed plane), and controls the drive module 24 to move. The drive module 24 moves the connection module 23 until the connection module 23 contacts the signal interface 12 to form an electrical connection, thus fixing the signal interface 12 to the fixed plane. This configuration enables the signal interface 12 of the biochemical sensor array 1 to be fixed using an electrically controlled method.

[0041] For example, such as Figure 2 As shown, the outer shell of the multi-channel biochemical analyzer 2 is a hexahedron, with a display screen 31 and buttons on the upper cover plate 41; the socket 21 is located on the side frame, which is connected to the upper cover plate 41 and the bottom shell 42. Figure 3 for Figure 2 The multi-channel biochemical analyzer 2 shown has its cover plate 41 removed, exposing the fixing unit located inside the outer shell mechanism. The fixing unit includes a socket 21, an in-situ detection module 22, a connection module 23, a drive module, a fixing plane (not shown in the figure), and a control module (not shown in the figure). The fixing platform is parallel to the plane where the upper cover plate 41 is located.

[0042] In some embodiments, the fixed plane is fixedly connected to the housing mechanism.

[0043] In some embodiments, the fixing platform and the housing mechanism are integrated into one structure, thus omitting the installation step of the fixing platform.

[0044] The multi-channel biochemical analyzer 2 provided in this embodiment includes a fixing unit for fixing the signal interface of the biochemical sensor array. The fixing unit includes a socket 21, a fixing plane, an in-situ detection module 22, a connection module 23, a drive module 24, and a control module 25. When the in-situ detection module 22 detects that the signal interface 12 is inserted into the socket 21, it generates an in-situ signal and transmits the in-situ signal to the control module 25. In response to the in-situ signal, the control module 25 controls the drive module 24 to move the connection module 23 until the connection module 23 contacts the signal interface 12 to form an electrical connection, and fixes the signal interface 12 on the fixing plane. Based on this, by using the connection module 23 to fix the signal interface 12 of the biochemical sensor array on the fixing plane, the biochemical sensor array 1 will not be displaced during the detection process, which is beneficial to improving the accuracy and stability of the signal; at the same time, the connection module 23 is electrically connected to the signal interface 12, which also realizes the input of the signal of the biochemical sensor array 1 into the multi-channel biochemical analyzer 2.

[0045] In some embodiments, the drive module includes a drive device and a transmission component, with the connection module located on the side of the transmission component closer to the signal interface; the drive device operates to move the transmission component, which in turn moves the connection module toward the signal interface until the connection module contacts the signal interface and fixes the signal interface on a fixed plane.

[0046] The transmission component is connected to the drive device and the connection module. The control module controls the drive device to output driving force. The transmission component moves under the action of the driving force, thereby driving the connection module to move closer to the signal interface until the connection module contacts the signal interface to form an electrical connection and fixes the signal interface on a fixed plane to prevent the signal interface from being displaced.

[0047] In some embodiments, such as Figure 3 As shown, the driving device includes a servo motor 241, and the transmission components include a gear 242 and a rack 243. The servo motor 241 and the gear 242 are coaxial, and the gear 242 meshes with the rack 243. The connecting module 23 is located on the side of the rack 243 near the signal interface (or fixed plane). The servo motor 241 rotates along its own axis by a preset angle, driving the gear 242 to rotate. The gear 242 drives the rack 243 to move along a first direction until the connecting module 23 contacts the signal interface and the signal interface is fixed on the fixed plane. The first direction is perpendicular to the axis of the servo motor 241.

[0048] In this embodiment, after the biochemical sensor array is inserted into the socket 21, the presence detection module 22 sends a presence signal to the control module. After the control module determines that the biochemical sensor array is in place through the program, it drives the servo motor 241 to rotate along its own axis by a preset angle, thereby driving the transmission gear 242 to rotate. Since the gear 242 meshes with the rack 243, the rotation of the gear 242 drives the rack 243 to move linearly. The connection module 23 is fixed at the end of the rack 243 near the signal interface (or fixed plane). The movement of the rack 243 causes the connection module 23 to contact the signal interface of the biochemical sensor array, forming an electrical path. At the same time, the signal interface is fixed on the fixed plane to prevent the signal interface from being displaced.

[0049] In some embodiments, such as Figure 4 As shown, the fixed unit 20 also includes a first communication interface 26, which is used to connect the control module and the drive device. The control module transmits the pulse width modulation (PWM) control signal to the drive device through the first communication interface 26, thereby controlling the operation of the drive device.

[0050] For example, the driving device includes a servo motor, and the control module transmits a PWM control signal to the servo motor through the first communication interface 26, thereby controlling the servo motor to rotate a preset angle.

[0051] In some embodiments, such as Figure 4 As shown, the fixed unit 20 also includes an independent power management module 27, which is used to control the voltage, current and power within the fixed unit 20, as well as to control the on and off of the power supply path within the fixed unit 20.

[0052] In some embodiments, such as Figure 5 As shown, the multi-channel biochemical analyzer also includes: a signal channel selection unit, a signal acquisition unit, and a control unit. The control module, signal channel selection unit, and signal acquisition unit of the fixed unit are all electrically connected to the control unit. The connection module is electrically connected to the signal channel selection unit, and the signal channel selection unit is electrically connected to the signal acquisition unit. The control unit is used to fix the signal interface of the biochemical sensor array based on the fixed unit, control the signal channel selection unit to select the signal access channel of the biochemical sensor, and control the signal acquisition unit to acquire the target signal of the signal access channel selected by the signal channel selection unit, and perform data processing on the acquired target signal to obtain the target detection index.

[0053] Among them, such as Figure 1As shown, the signal interface 12 includes a first signal interface 121 and multiple second signal interfaces 122. The first signal interface 121 is electrically connected to the common terminal 12 of the biochemical sensor 11, and the second signal interfaces 122 are electrically connected to the other end of the biochemical sensor 11 in a one-to-one correspondence. One signal access channel includes the first signal interface 121, one second signal interface 122, and a biochemical sensor 11 correspondingly connected between the first signal interface 121 and the second signal interface 122. For example, as... Figure 1 As shown, the biochemical sensor array 1 includes 25 biochemical sensors 11, 1 first signal interface 121 and 25 second signal interfaces 122, and the biochemical sensor array includes 25 signal access channels.

[0054] The connection module is electrically connected to the signal channel selection unit, and inputs the signal from the biochemical sensor array to the signal channel selection unit.

[0055] The signal channel selection unit has a gating function. It selects one of the multiple signal access channels on the biochemical sensor array, connecting it to the signal acquisition unit each time. The signal acquisition unit samples and converts the target signal from the connected channel, and the control unit processes the target signal to obtain the target detection index corresponding to that channel. Then, the signal channel selection unit selects another channel to connect to the signal acquisition unit, and the signal acquisition unit and control unit repeat the above steps. This process continues until the target detection values ​​for all signal access channels on the biochemical sensor array are obtained.

[0056] The control unit is the core component of the multi-channel biochemical analyzer, possessing data processing capabilities. The control unit controls the operating logic and parameter configuration of each component of the multi-channel biochemical analyzer through various communication protocols, enabling the predetermined tasks of the multi-channel biochemical analyzer to be executed logically. The control unit includes a microcontroller. For example, the control unit includes an STM32F407ZET6 microcontroller.

[0057] The signal channel selection unit includes all electronic devices with gating functions known to those skilled in the art, such as single-pole multi-throw switches, switching chips, or selectors, and is not limited thereto. For example, the signal channel selection unit includes a multiplexer chip CD4051.

[0058] The signal acquisition unit includes an analog-to-digital converter (ADC). In some embodiments, the analog-to-digital converter inside the control unit is used as the signal acquisition unit.

[0059] The multi-channel biochemical analyzer provided in this embodiment uses a connection module to fix the signal interface of the biochemical sensor array on a fixed plane, so that the biochemical sensor array will not be displaced during the detection process, which is beneficial to improving the accuracy and stability of the signal; at the same time, the connection module inputs the signal interface into the multi-channel biochemical analyzer, realizing the measurement and reading of signals from multiple biochemical sensors on the biochemical sensor array.

[0060] In some embodiments, such as Figure 5 As shown, the multi-channel biochemical analyzer also includes at least one of a display management unit, a storage unit, a power management unit, an interaction unit, and a communication unit; the display management unit, storage unit, power management unit, interaction unit, and communication unit are all electrically connected to the control unit.

[0061] The display management unit includes a display driving circuit for driving a display screen to display target detection indicators and / or configuration information of a multi-channel biochemical analyzer. For example, the display management unit includes a thin-film transistor driving circuit, and the display screen is a liquid crystal display.

[0062] The storage unit is used to store target signals and / or target detection indicators. This disclosure does not limit the type of storage unit; any electronic device with storage function known to those skilled in the art can be used, such as flash memory. Exemplarily, the storage unit includes a flash memory chip W25Q128.

[0063] The power management unit controls the voltage, current, and power of the multi-channel biochemical analyzer. Specifically, it controls the voltage, current, and power of the input power supply to the entire multi-channel biochemical analyzer. For example, the power management unit includes a TPS7333 voltage regulator chip.

[0064] The interactive unit provides a user interface and, in response to user actions, sets the parameters of the multi-channel biochemical analyzer. For example, such as... Figure 2 As shown, the multi-channel biochemical analyzer includes a display screen 31 and buttons 51. Users can configure the relevant parameters of the multi-channel biochemical analyzer through the buttons and the display screen.

[0065] The communication unit is used to transmit target detection indicators to a remote server, receive control commands sent by the remote server, and forward the control commands to the control unit, which then performs the corresponding calculations. The communication unit includes a wireless communication module and / or a wired communication module. For example, the wireless communication module includes the ESP-01F wireless communication module.

[0066] For example, such as Figure 5As shown, the control unit communicates with the control module of the fixed unit via the UART communication protocol, with the signal channel selection unit via the GPIO communication protocol, with the power management module via the GPIO communication protocol, with the communication unit via the UART communication protocol, with the display management unit via the SPI communication protocol, with the interaction module via the GPIO communication protocol, and with the storage module via the SPI communication protocol. The signal acquisition unit utilizes the internal ADC of the control unit. The control unit controls the working logic and parameter configuration of each unit through various communication protocols, enabling the multi-channel biochemical analyzer to execute its predetermined tasks logically.

[0067] The multi-channel biochemical analyzer provided in this embodiment not only has the ability to process, acquire, and calculate sensor signals, but also has functions such as real-time display, communication, local storage, and human-computer interaction, making the multi-channel biochemical analyzer more feature-rich and more intelligent to use.

[0068] In some embodiments, such as Figure 3 As shown, the connection module 23 includes: a spring pin header 231; the spring pin header 231 includes a first spring pin and a plurality of second spring pins, the first spring pin and the second spring pins are arranged sequentially along the extension direction of the socket 21, the first spring pin corresponds to the first signal interface, and the second spring pin corresponds to the second signal interface one by one.

[0069] The spring pin includes a fixedly connected spring and a conductive probe, with the conductive probe located on the side of the spring closer to the signal interface. Exemplarily, the conductive probe includes a metal probe.

[0070] With this configuration, driven by the drive module, the conductive probe of the spring pin header contacts the signal interface, forming an electrical path. Utilizing the rebound force generated by spring compression, the spring pin header presses the signal interface firmly onto the fixed plane, thus achieving signal interface fixation.

[0071] In some embodiments, such as Figure 3 As shown, the fixing unit also includes a spring pin limit plate 29.

[0072] The spring pin limit plate 29 is used to limit the position of the spring pin 231, prevent the spring pin 231 from moving too far toward the signal interface, and avoid excessive pressure from the spring pin 231 pressing the signal interface, which could damage the signal interface.

[0073] In some embodiments, such as Figure 5As shown, the multi-channel biochemical analyzer also includes a signal processing unit, a connection module, and a signal channel selection unit, all of which are electrically connected to the signal processing unit. The signal processing unit is used to amplify and / or filter the signal transmitted by the connection module and transmit the processed signal to the signal channel selection unit.

[0074] The signal processing unit is electrically connected to the signal interface via a connection module. The signal input from the biochemical sensor array is sent to the signal processing unit, and after amplification and / or filtering by the signal processing unit, the processed signal is transmitted to the signal channel selection unit.

[0075] In some embodiments, the signal of the biochemical sensor includes a voltage signal, and the signal processing unit includes at least one of a differential amplifier circuit, a voltage follower circuit, and a filter circuit; wherein, the differential amplifier circuit is used to amplify the voltage signal by a preset factor; the voltage follower circuit is used to improve the load-carrying capacity of the voltage signal; and the filter circuit is used to filter out noise in the voltage signal and improve signal stability.

[0076] In some embodiments, such as Figure 6 As shown, the differential amplifier circuit includes: a first operational amplifier U7A, a first resistor R16, a second resistor R12, a third resistor R19, and a fourth resistor R28; the first operational amplifier U7A includes a first input terminal, a second input terminal, a first output terminal, a first power supply pin, and a second power supply pin. The first input terminal is electrically connected to a first signal interface. The first resistor R16 is connected in series between the first input terminal and the first signal interface, and the second resistor R12 is connected in series between the first input terminal and the first output terminal; the second input terminal is electrically connected to a second signal interface, the third resistor R19 is connected in series between the second input terminal and the second signal interface, and the fourth resistor R28 is connected in series between the second input terminal and the second power supply pin; the resistance ratio of the second resistor R12 to the first resistor R16 and the resistance ratio of the fourth resistor R28 to the third resistor R19 are both equal to a preset multiple, which is equal to the amplification factor, that is, the amplification factor of the voltage signal is equal to the resistance ratio of the second resistor R12 to the first resistor R16, or the amplification factor of the voltage signal is equal to the resistance ratio of the fourth resistor R28 to the third resistor R19.

[0077] The first input terminal is electrically connected to the first signal interface via a first spring pin, and the second input terminal is electrically connected to the second signal interface via a second spring pin.

[0078] For example, such as Figure 6As shown, the first operational amplifier U7A includes an LM358M / TR operational amplifier. The pin corresponding to digital 1 is the first output terminal, the pin corresponding to digital 2 is the first input terminal, the pin corresponding to digital 3 is the second input terminal, and the pin corresponding to digital 4 is the second power supply pin. The first power supply pin is connected to a 5V high level, and the second power supply pin is connected to a -5V low level. V1_2 is electrically connected to the first signal interface. V1_1 and V1_2 are differential voltage input terminals, where V1_2 is electrically connected to the first signal interface via a first spring pin, and V1_1 is electrically connected to the second signal interface via a second spring pin. The second resistor R12 has a resistance of 499KΩ, the first resistor R16 has a resistance of 2KΩ, and their resistance ratio is approximately 250. The fourth resistor R28 has a resistance of 499KΩ, and the third resistor R19 has a resistance of 2KΩ, and their resistance ratio is also 250. This differential amplifier circuit amplifies the voltage signal from the biochemical sensor by 250 times.

[0079] It should be noted that, Figure 6 This illustration merely demonstrates how a differential amplifier circuit amplifies a voltage signal by 250 times, and does not constitute a limitation on the multi-channel biochemical analyzer provided in this disclosure. In other embodiments, the amplification factor can be flexibly set according to requirements, and is not limited herein.

[0080] In some embodiments, such as Figure 6 As shown, the voltage follower circuit includes a second operational amplifier U7B; the second operational amplifier U7B includes a third input terminal, a fourth input terminal, and a second output terminal, the third input terminal being electrically connected to the first output terminal, and the fourth input terminal being electrically connected to the second output terminal.

[0081] The voltage follower circuit is located after the differential amplifier circuit.

[0082] For example, such as Figure 6 As shown, the second operational amplifier U7B includes an LM358M / TR operational amplifier, with digital 5 as the third input terminal, digital 6 as the fourth input terminal, and digital 7 as the second output terminal.

[0083] In some embodiments, such as Figure 6 As shown, the filter circuit includes a fifth resistor R17 and a first capacitor C18; the input terminal of the fifth resistor R17 is electrically connected to the second output terminal, the output terminal of the fifth resistor R17 is electrically connected to the input terminal of the first capacitor C18, the output terminal of the first capacitor C18 is grounded, and the output terminal of the fifth resistor R17 is also electrically connected to the signal acquisition unit.

[0084] For example, such as Figure 6 As shown, the AD1 terminal is used for electrical connection to the signal acquisition unit.

[0085] In some embodiments, the multichannel biochemical analyzer further includes a constant current source circuit, which is used to generate a differential voltage signal between the first signal interface and the second signal interface.

[0086] The constant current source circuit is electrically connected to the signal interface via a connection module, thereby supplying power to the signal access channel and ensuring a constant current in the signal access channel, forming a differential voltage between the first and second signal interfaces. The two differential voltages corresponding to each signal access channel are input to a differential amplifier circuit, which converts them into single-ended voltage signals. These signals are then acquired by the signal acquisition unit, and the control unit calculates the resistance value of each signal access channel based on Ohm's law.

[0087] For example, combined Figure 1 The biochemical sensor array is equipped with 25 biochemical sensors, which are 25 signal access channels. A 1mA constant current source is used to form a circuit with each of the 25 signal access channels through a connection module (or spring pin header). At this time, the first signal interface and the second signal interface of each signal access channel form a pair of differential voltage signals.

[0088] In some embodiments, such as Figure 7 As shown, the constant current source circuit includes a power supply chip U9, a sixth resistor R13, and a ground terminal GND; wherein, the first terminal of the power supply chip U9 is electrically connected to the input terminal of the sixth resistor R13, the second terminal of the power supply chip U9 and the second spring pin are both electrically connected to the output terminal of the sixth resistor R13, and the first spring pin is electrically connected to the ground terminal GND.

[0089] For example, such as Figure 7 As shown, the power supply chip U9 is an LM234DT chip. The input terminal of the sixth resistor R13 is electrically connected to the adjustment pin (ADJ) of the LM234DT chip, and the output terminal of the sixth resistor R13 is electrically connected to the output pin (V-) of the power supply chip U9. The connection point between the output terminal of the sixth resistor R13 and the output pin (V-) of the power supply chip U9 is electrically connected to the second spring pin, and the first spring pin is electrically connected to the ground terminal, thereby realizing the connection of the constant current source circuit to each signal access channel. Among them, the PORT1_1 port is electrically connected to the second signal interface through the second spring pin, and the COM port is electrically connected to the first signal interface through the first spring pin.

[0090] In some embodiments, such as Figure 7 As shown, the output pin (V-) of the power chip U9 is connected in series with the PORT1_1 port with resistor R14; the ground terminal is connected in series with the COM port with resistor R21 and resistor R20; resistor R15 and second capacitor C14 are connected in series to ground at the PORT1_1 port, and resistor R27 and third capacitor C19 are connected in series to ground at the COM port.

[0091] In some embodiments, the signal channel selection unit includes at least one selector, which is electrically connected to the signal acquisition unit; the selector is used to select any one of the signal access channels to be connected to the signal acquisition unit.

[0092] One of the signal access channels includes a first signal interface, a second signal interface, and a biochemical sensor connected between the first and second signal interfaces. The input terminal of the selector is electrically connected to the spring pin header, that is, the selector is electrically connected to the signal interface of the biochemical sensor array, thus realizing the electrical connection between the signal access channel and the selector.

[0093] The selector has a multi-channel selection function. Each time, the selector selects one signal access channel to connect with the signal acquisition unit. The signal acquisition unit then acquires the target signal of that group of signal channels. One signal access channel is selected and one target signal is sampled at a time until the target signals of all signal access channels on the biochemical sensor array have been acquired, completing one complete sampling cycle.

[0094] In some embodiments, the selector includes N primary selectors and one secondary selector. The primary selectors are electrically connected to the secondary selectors, and the secondary selector is electrically connected to the signal acquisition unit. The primary selector is used to select any one of the corresponding multi-channel signal access channels to be connected to the secondary selector. The secondary selector is used to select one of the N primary selectors to be electrically connected to the signal acquisition unit. The secondary selector includes an M-to-1 selector. Wherein, M and N are positive integers, N is greater than or equal to 2, and M is greater than or equal to N.

[0095] In this embodiment, the signal access channels are pre-divided into N groups. Each group's signal access channel is electrically connected to the corresponding primary connector via spring pin headers. Each primary selector selects one of the multiple signal access channels in the corresponding group to connect with the secondary selector. The secondary selector selects from the N primary selectors, choosing one primary selector to connect with the signal acquisition unit, thus connecting any one of the signal access channels to the signal acquisition unit. The signal acquisition unit then acquires the target signal of that signal access channel, thereby enabling selection / sampling of any one of the signal access channels. Only one channel is selected (sampled) at a time, and the selection (sampling) step is repeated until all signal access channels are selected (sampled).

[0096] For example, the biochemical sensor array includes 25 signal access channels. The path selection unit includes four 8-to-1 primary selectors and one 4-to-1 secondary selector. Signal access channels 1 to 8 enter primary selector 1, signal access channels 9 to 16 enter primary selector 2, signal access channels 17 to 24 enter primary selector 3, and signal access channel 25 enters primary selector 4. The secondary selector selects primary selectors 1 to 4, thereby enabling the selection of any one of the 25 signal access channels. The signal acquisition unit then acquires the target signal of that signal access channel. This selection / sampling is repeated 25 times to complete one complete sampling cycle.

[0097] In some embodiments, the outer shell of the multi-channel biochemical analyzer is made using metamaterial 3D printing technology, which combines the characteristics of high temperature resistance, high pressure resistance, good airtightness and light weight. It can be widely used in harsh environments such as aerospace, deep sea and polar regions, thus broadening the application scenarios of the multi-channel biochemical analyzer.

[0098] Based on the above embodiments, this disclosure also provides a control method for any of the above-mentioned multi-channel biochemical analyzers, which has corresponding beneficial effects. The similarities can be understood with reference to the above text, and will not be repeated hereafter.

[0099] In some embodiments, such as Figure 1 As shown, the biochemical sensor array includes multiple biochemical sensors 11 arranged in an array and a signal interface 12 connected to the biochemical sensors; as Figure 3-4 As shown, the multi-channel biochemical analyzer 2 includes a fixing unit for fixing the signal interface 12 of the biochemical sensor array. The fixing unit includes: a socket 21, a fixing plane, an in-situ detection module 22, a connection module 23, a drive module 24, and a control module 25. The in-situ detection module 22, the drive module 24, and the connection module 23 are all electrically connected to the control module 25. The connection module 23 is fixed to the drive module 24.

[0100] The connector 21 is disposed on the housing structure and extends through the housing structure in the thickness direction. The connector 21 allows the signal interface 12 of the biochemical sensor array 1 to be inserted. The presence detection module 22 is used to detect the insertion of the signal interface 12 into the connector 21, generate a presence signal, and transmit the presence signal to the control module 25. Exemplarily, the presence detection module 22 includes a photoelectric presence sensor. A fixed plane is used to place the signal interface 12 of the biochemical sensor array 1. The control module 25 includes a microcontroller unit (MCU) on which the control program is stored.

[0101] The control method for a multi-channel biochemical analyzer includes the following steps:

[0102] S100: The control module responds to the presence signal transmitted by the presence detection module, controls the drive module to move, and the drive module drives the connection module to move until the connection module contacts the signal interface and fixes the signal interface on the fixed plane.

[0103] The presence signal is generated by the presence detection module when it detects that the signal interface has been inserted into the socket.

[0104] In this embodiment, the control module 25, responding to the presence signal transmitted by the presence detection module 22, determines that the signal interface 12 has been inserted into the socket 21 (or is located on the fixed plane), and controls the drive module 24 to move. The drive module 24 drives the connection module 23 to move until the connection module 23 contacts the signal interface 12 to form an electrical connection, and fixes the signal interface 12 to the fixed plane. This configuration achieves the electric control method for fixing the signal interface 12 of the biochemical sensor array 1.

[0105] The connection module 23 serves both as a clamping mechanism for fixing the signal interface 12 and as a signal input terminal for the multi-channel biochemical analyzer 2, connecting the signal from the biochemical sensor array 1 to the multi-channel biochemical analyzer 2. The connection module 23 is connected to the drive module 24 and moves under the power of the drive module 24, contacting the signal interface 12 to form an electrical connection, thus enabling the input of the signal from the biochemical sensor array 1 to the multi-channel biochemical analyzer 2. Simultaneously, it presses the signal interface 12 firmly onto the fixed plane, fixing the signal interface 12 and preventing displacement of the biochemical sensor array 1 during subsequent detection, which helps improve the accuracy and stability of the signal.

[0106] In some embodiments, the drive module includes a drive device and a transmission assembly, with the connection module located on the side of the transmission assembly closer to the signal interface. The control method includes the following steps:

[0107] In response to the presence signal transmitted by the presence detection module, the control module controls the drive device to move, thereby moving the transmission component. The transmission component moves the connection module toward the signal interface until the connection module contacts the signal interface and fixes the signal interface on the fixed plane.

[0108] The transmission component is connected to the drive device and the connection module. The control module controls the drive device to output driving force. The transmission component moves under the action of the driving force, thereby driving the connection module to move closer to the signal interface until the connection module contacts the signal interface to form an electrical connection and fixes the signal interface on a fixed plane to prevent the signal interface from being displaced.

[0109] In some embodiments, such as Figure 3As shown, the drive device includes a servo motor 241, and the transmission assembly includes a gear 242 and a rack 243. The servo motor 241 and the gear 242 are coaxial, and the gear 242 meshes with the rack 243. The connection module 23 is located on the side of the rack 243 closer to the signal interface (or fixed plane). The control method includes the following steps:

[0110] The control module responds to the presence signal transmitted by the presence detection module, controls the servo motor to rotate a preset angle along its own axis, drives the gear to rotate, and the gear drives the rack to move along the first direction until the connection module contacts the signal interface and the signal interface is fixed on the fixed plane.

[0111] The first direction is perpendicular to the axis of the servo motor.

[0112] In this embodiment, after the signal interface of the biochemical sensor array is inserted into the socket 21, the presence detection module 22 sends a presence signal to the control module. After the control module determines that the biochemical sensor array is in place through the program, it drives the servo motor 241 to rotate along its own axis by a preset angle, thereby driving the transmission gear 242 to rotate. Since the gear 242 meshes with the rack 243, the rotation of the gear 242 drives the rack 243 to move linearly. The connection module 23 is fixed at the end of the rack 243 near the signal interface (or the fixed plane). The movement of the rack 243 causes the connection module 23 to contact the signal interface of the biochemical sensor array, forming an electrical path. At the same time, the signal interface is fixed on the fixed plane to prevent the signal interface from being displaced.

[0113] In some embodiments, such as Figure 5 As shown, the multi-channel biochemical analyzer also includes: a signal channel selection unit, a signal acquisition unit, and a control unit. The fixing unit, the signal channel selection unit, and the signal acquisition unit are all electrically connected to the control unit. The connection module is electrically connected to the signal channel selection unit, and the signal channel selection unit is electrically connected to the signal acquisition unit.

[0114] The control method also includes the following steps:

[0115] S210: The control unit fixes the signal interface of the biochemical sensor array based on the fixed unit, and controls the signal channel selection unit to select the signal access channel of the biochemical sensor.

[0116] Among them, such as Figure 1 As shown, the signal interface 12 includes a first signal interface 121 and multiple second signal interfaces 122. The first signal interface 121 is electrically connected to the common terminal 12 of the biochemical sensor 11, and the second signal interfaces 122 are electrically connected to the other end of the biochemical sensor 11 in a one-to-one correspondence. One signal access channel includes the first signal interface 121, one second signal interface 122, and a biochemical sensor 11 correspondingly connected between the first signal interface 121 and the second signal interface 122. For example, as... Figure 1 As shown, the biochemical sensor array 1 includes 25 biochemical sensors 11, 1 first signal interface 121 and 25 second signal interfaces 122, and the biochemical sensor array includes 25 signal access channels.

[0117] The connection module is electrically connected to the signal channel selection unit, and inputs the signal from the biochemical sensor array to the signal channel selection unit.

[0118] S220, the control unit controls the signal acquisition unit to acquire the target signal of the biochemical sensor in the access channel.

[0119] S230, the control unit processes the collected target signals to obtain target detection indicators.

[0120] In this embodiment, the signal channel selection unit has a gating function. The signal channel selection unit selects multiple signal access channels on the biochemical sensor array. Each time, it selects one signal access channel to connect with the signal acquisition unit. The signal acquisition unit samples and converts the target signal of the connected signal access channel, and then the control unit processes the target signal to obtain the target detection index corresponding to that group of signal access channels. Then, the signal channel selection unit selects another signal access channel to connect with the signal acquisition unit, and the signal acquisition unit and control unit repeat the above steps. This process continues until the target detection values ​​corresponding to all signal access channels on the biochemical sensor array are obtained.

[0121] In some embodiments, the control method further includes the following steps:

[0122] The control unit generates display commands and storage commands;

[0123] The display command is used to control the display management module to drive the display screen and display the target detection indicators and / or the configuration information of the multi-channel biochemical analyzer on the display screen; the storage command is used to control the storage unit to save the target signal and / or the target detection indicators.

[0124] In this embodiment, after completing the detection of all signal access channels on the biochemical sensor array, the control display shows the detection results, and the control storage unit stores the detection results. The detection results include target detection indicators and target signals (e.g., voltage signals). Furthermore, the control display can also show the configuration information of the multi-channel biochemical analyzer.

[0125] In some embodiments, after "generating display instructions and storage instructions", the control method further includes the following steps:

[0126] The control unit sends a release command to the fixing unit;

[0127] The release command is used to control the fixed unit to release the signal interface of the biochemical sensor array. After completing the detection of all signal access channels on the biochemical sensor array, the signal interface is released, the detected biochemical sensor array is removed, and a new biochemical sensor array to be detected is selected.

[0128] For example, such as Figure 10 As shown, the control method includes the following steps:

[0129] S310, Peripheral initialization.

[0130] This step initializes the hardware peripheral drivers.

[0131] S320. Determine whether the biochemical sensor array is in place.

[0132] In this step, based on the presence signal transmitted by the photoelectric presence sensor, it is determined whether the biochemical sensor array is in place. If it is in place, the determination result is "yes", and S303 is executed; if it is not in place, and the determination result is "no", the process returns to re-execute this step.

[0133] S330, signal interface for accelerated biochemical sensor array.

[0134] This step controls the servo motor to rotate at a preset angle, which drives the gear to rotate. Since the gear meshes with the rack, the rotation of the gear drives the rack to move in a straight line. The spring pin is fixed at the end of the rack near the signal interface (or fixed plane). The movement of the rack causes the spring pin to contact the signal interface of the biochemical sensor array to form an electrical connection, while clamping the sensor signal interface.

[0135] S340, Signal Access Channel Selection.

[0136] This step involves selecting a signal access channel, with each channel being selected and electrically connected to the back-end circuit.

[0137] S350, signal amplification and processing.

[0138] The signal processing unit includes a differential amplifier circuit, which amplifies the signal from the selected signal input channel. The signal processing circuit also includes a voltage follower circuit and / or a filter circuit.

[0139] S360, signal sampling.

[0140] This step involves the signal acquisition unit sampling and converting the target signal. For example, the signal acquisition unit includes an analog-to-digital converter (ADC) used to convert the analog signal into a digital signal to obtain a voltage value.

[0141] S370, Sampling data processing and calculation.

[0142] In this step, the control unit calculates the average of the voltage values ​​transmitted by the signal acquisition unit, and then substitutes the average into Ohm's law to obtain the resistance value.

[0143] S380, Detection result display and storage.

[0144] In this step, the test results are displayed on the screen and saved in the storage unit.

[0145] S390, release the signal interface of the biochemical sensor array.

[0146] At this step, the control unit releases the signal interface, completing the detection of one biochemical sensor array. Then, it returns to execute S320, where the user unplugs the detected biochemical sensor array and inserts a new biochemical sensor array for detection.

[0147] It should be noted that, in this document, relational terms such as "first" and "second" are used merely to distinguish one entity or operation from another, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Furthermore, the terms "comprising," "including," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements includes not only those elements but also other elements not expressly listed, or elements inherent to such a process, method, article, or apparatus. Without further limitations, an element defined by the phrase "comprising one..." does not exclude the presence of other identical elements in the process, method, article, or apparatus that includes said element.

[0148] The above description is merely a specific embodiment of this disclosure, enabling those skilled in the art to understand or implement it. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the general principles defined herein may be implemented in other embodiments without departing from the spirit or scope of this disclosure. Therefore, this disclosure is not to be limited to the embodiments described herein, but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.

Claims

1. A multi-channel biochemical analyzer, characterized in that, The multi-channel biochemical analyzer is used to detect a biochemical sensor array, which includes multiple biochemical sensors arranged in an array and a signal interface connected to the biochemical sensors. The multi-channel biochemical analyzer includes: a fixing unit, which is used to fix the signal interface of the biochemical sensor array; The fixing unit includes: a socket, a fixing plane, an in-situ detection module, a connection module, a drive module, and a control module; The in-situ detection module, the drive module, and the connection module are all electrically connected to the control module; the connection module is connected to the drive module. The control module is used to control the movement of the drive module in response to the presence signal transmitted by the presence detection module. The drive module drives the connection module to move until the connection module contacts the signal interface to form an electrical connection and fixes the signal interface on the fixed plane. The presence signal is generated by the presence detection module when it detects that the signal interface is inserted into the socket.

2. The multi-channel biochemical analyzer according to claim 1, characterized in that, The drive module includes: a drive device and a transmission assembly; the connection module is located on the side of the transmission assembly closer to the signal interface; The drive device operates, causing the transmission component to move. The transmission component then moves the connection module toward the signal interface until the connection module contacts the signal interface and fixes the signal interface to the fixed plane.

3. The multi-channel biochemical analyzer according to claim 2, characterized in that, The drive device includes a servo motor, the transmission assembly includes a gear and a rack, the servo motor is coaxial with the gear, the gear meshes with the rack, and the connection module is located on the side of the rack near the signal interface; The servo motor rotates at a preset angle along its own axis, causing the gear to rotate. The gear then drives the rack to move along a first direction until the connecting module contacts the signal interface and the signal interface is fixed on the fixed plane. The first direction is perpendicular to the axis of the servo motor.

4. The multi-channel biochemical analyzer according to claim 1, characterized in that, Also includes: The system includes a signal channel selection unit, a signal acquisition unit, and a control unit. The control module, the signal channel selection unit, and the signal acquisition unit are all electrically connected to the control unit. The connection module is electrically connected to the signal channel selection unit, and the signal channel selection unit is electrically connected to the signal acquisition unit. The control unit is used to fix the signal interface of the biochemical sensor array based on the fixing unit, control the signal channel selection unit to select the signal access channel of the biochemical sensor, and control the signal acquisition unit to acquire the target signal of the signal access channel selected by the signal channel selection unit, and perform data processing on the acquired target signal to obtain the target detection index. The signal interface includes a first signal interface and multiple second signal interfaces. The first signal interface is electrically connected to the common terminal of the biochemical sensor, and the second signal interfaces are electrically connected to the other end of the biochemical sensor in a one-to-one correspondence. One signal access channel includes the first signal interface, a second signal interface, and a biochemical sensor correspondingly connected between the first signal interface and the second signal interface.

5. The multi-channel biochemical analyzer according to claim 4, characterized in that, The connection module includes: a spring pin header; The spring pin header includes a first spring pin and multiple second spring pins. The first spring pin corresponds to the first signal interface, and the second spring pins correspond one-to-one with the second signal interfaces.

6. The multi-channel biochemical analyzer according to claim 4, characterized in that, Also includes: The signal processing unit is electrically connected to the connection module and the signal channel selection unit. The signal processing unit is used to amplify and / or filter the signal transmitted by the connection module and transmit the processed signal to the signal channel selection unit.

7. The multi-channel biochemical analyzer according to claim 6, characterized in that, The signal includes a voltage signal, and the signal processing unit includes at least one of a differential amplifier circuit, a voltage follower circuit, and a filter circuit; The differential amplifier circuit is used to amplify the voltage signal by a preset factor; The voltage follower circuit is used to improve the load-carrying capacity of the voltage signal; The filtering circuit is used to filter out noise from the voltage signal.

8. The multi-channel biochemical analyzer according to claim 7, characterized in that, The differential amplifier circuit includes: a first operational amplifier, a first resistor, a second resistor, a third resistor, and a fourth resistor; the first operational amplifier includes a first input terminal, a second input terminal, a first output terminal, a first power supply pin, and a second power supply pin; the first input terminal is electrically connected to a first signal interface; the first resistor is connected in series between the first input terminal and the first signal interface; the second resistor is connected in series between the first input terminal and the first output terminal; the second input terminal is electrically connected to a second signal interface; the third resistor is connected in series between the second input terminal and the second signal interface; the fourth resistor is connected in series between the second input terminal and the second power supply pin; the resistance ratio of the second resistor to the first resistor and the resistance ratio of the fourth resistor to the third resistor are both equal to the preset multiple; The voltage follower circuit includes a second operational amplifier; the second operational amplifier includes a third input terminal, a fourth input terminal, and a second output terminal, the third input terminal being electrically connected to the first output terminal, and the fourth input terminal being electrically connected to the second output terminal; The filtering circuit includes a fifth resistor and a first capacitor; the input terminal of the fifth resistor is electrically connected to the second output terminal, the output terminal of the fifth resistor is electrically connected to the input terminal of the first capacitor, the output terminal of the first capacitor is grounded, and the output terminal of the fifth resistor is also electrically connected to the signal acquisition unit.

9. The multi-channel biochemical analyzer according to claim 5, characterized in that, Also includes: A constant current source circuit is used to generate a differential voltage signal between the first signal interface and the second signal interface.

10. The multi-channel biochemical analyzer according to claim 9, characterized in that, The constant current source circuit includes a power chip, a sixth resistor, and a ground terminal; The first end of the power chip is electrically connected to the input end of the sixth resistor, the second end of the power chip and the second spring pin are both electrically connected to the output end of the sixth resistor, and the first spring pin is electrically connected to the grounding end.

11. The multi-channel biochemical analyzer according to claim 4, characterized in that, The signal channel selection unit includes at least one selector, which is electrically connected to the signal acquisition unit; the selector is used to select any one of the signal access channels to be connected to the signal acquisition unit.

12. The multi-channel biochemical analyzer according to claim 11, characterized in that, The selector includes N primary selectors and one secondary selector. The primary selectors are electrically connected to the secondary selector, and the secondary selector is electrically connected to the signal acquisition unit. The primary selector is used to select any one of the corresponding multiple signal access channels to be connected to the secondary selector; The secondary selector is used to select one of the N primary selectors to be electrically connected to the signal acquisition unit; the secondary selector includes an M-to-1 selector; Where M and N are positive integers, N is greater than or equal to 2, and M is greater than or equal to N.

13. The multi-channel biochemical analyzer according to claim 4, characterized in that, Also includes: Display management unit, storage unit, power management unit, interaction unit, and communication unit; The display management unit is used to drive the display screen to display the target detection index and / or the configuration information of the multi-channel biochemical analyzer on the display screen; The storage unit is used to store the target signal and / or the target detection index; The power management unit is used to control the voltage, current and power of the multi-channel biochemical analyzer; The interactive unit is used to provide an operation interface to the user and, in response to the user's operation, to set the parameters of the multi-channel biochemical analyzer. The communication unit is used to transmit the target detection indicators to the remote server and to forward the control commands sent by the remote server to the control unit. The display management unit, the storage unit, the power management unit, the interaction unit, and the communication unit are all electrically connected to the control unit.

14. A control method for a multi-channel biochemical analyzer, characterized in that, The multi-channel biochemical analyzer is used to detect a biochemical sensor array, which includes multiple biochemical sensors arranged in an array and a signal interface connected to the biochemical sensors. The multi-channel biochemical analyzer includes a fixing unit, which is used to fix the signal interface of the biochemical sensor array. The fixing unit includes: a socket, a fixing plane, an in-situ detection module, a connection module, a drive module, and a control module; The in-situ detection module, the drive module, and the connection module are all electrically connected to the control module; the connection module is fixed to the drive module. The control method includes: The control module responds to the presence signal transmitted by the presence detection module and controls the drive module to move. The drive module drives the connection module to move until the connection module contacts the signal interface and fixes the signal interface on the fixed plane. The presence signal is generated by the presence detection module when it detects that the signal interface is inserted into the socket.

15. The control method according to claim 14, characterized in that, The multi-channel biochemical analyzer further includes: a signal channel selection unit, a signal acquisition unit, and a control unit. The fixing unit, the signal channel selection unit, and the signal acquisition unit are all electrically connected to the control unit. The connection module is electrically connected to the signal channel selection unit, and the signal channel selection unit is electrically connected to the signal acquisition unit. The control method further includes: The control unit fixes the signal interface of the biochemical sensor array based on the fixing unit, and controls the signal channel selection unit to select the signal access channel of the biochemical sensor; The control unit controls the signal acquisition unit to acquire the target signals of the biochemical sensors in the access channel; The control unit processes the collected target signals to obtain target detection indicators. The signal interface includes a first signal interface and multiple second signal interfaces. The first signal interface is electrically connected to the common terminal of the biochemical sensor, and the second signal interfaces are electrically connected to the other end of the biochemical sensor in a one-to-one correspondence. One signal access channel includes the first signal interface, a second signal interface, and a biochemical sensor correspondingly connected between the first signal interface and the second signal interface.

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