限位可扩张主动脉瓣管道及其制备
By attaching a collagen fiber coating to the aortic valve conduit and optimizing the suture method, the problem of requiring open-heart valve replacement due to the failure of bioprosthetic valves in existing technologies has been solved. This provides the conditions for interventional valve replacement and achieves stable, hemorrhage-proof, biocompatible, rapid endothelialization, and excellent mechanical properties.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- BEIJING BALANCE MEDICAL
- Filing Date
- 2024-12-06
- Publication Date
- 2026-07-17
AI Technical Summary
Existing aortic valve conduits require a second open-heart surgery to replace the valve after bioprosthetic valve failure. The coating is prone to peeling off, the anti-bleeding effect is poor, the biocompatibility is poor, the endothelialization rate is slow, the mechanical properties are insufficient, and the surgical operability and compliance are insufficient.
The aortic valve preliminary conduit is made with a collagen fiber coating. A stable collagen fiber coating is formed through two chemical cross-linking processes. The suture method is optimized and the conduit parameters are controlled to adapt to high pulsatile pressure, providing conditions for interventional valve replacement.
It achieves valve replacement without open-chest surgery, has a stable coating, excellent anti-bleeding effect, good biocompatibility, fast endothelialization, excellent mechanical properties, adaptability to high pulsatile pressure, and reduces patient injury.
Smart Images
Figure CN120241323B_ABST