一种生物分子检测芯片及双偏振差分的生物分子检测方法
By coupling gold nanoparticles and a ridge-shaped waveguide microring resonator, and utilizing the wavelength shift difference method of the resonant peaks of TE and TM polarization modes, high-sensitivity and high-precision biomolecule detection was achieved, solving the sensitivity and accuracy problems of single-molecule detection in existing technologies.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- SHENZHEN TECH UNIV
- Filing Date
- 2025-03-28
- Publication Date
- 2026-07-17
AI Technical Summary
Existing biomolecular detection technologies struggle to achieve high sensitivity and precision in single-molecule detection, especially in the presence of environmental noise and interference, making it difficult to distinguish between biological signals and environmental change signals.
By coupling gold nanotriangular sheets with a micro-ring resonator based on a ridge-shaped optical waveguide structure, high sensitivity and high precision detection of biomolecules are achieved by comparing the wavelength shift of the resonant peaks in TE polarization mode and TM polarization mode.
Highly sensitive and reliable single-molecule detection has been achieved in the visible to near-infrared band, which can effectively distinguish biological signals from environmental change signals and reduce the impact of environmental noise.
Smart Images
Figure CN120255075B_ABST