基于光激发电驱动活性氧通道的试剂盒及检测方法
The kit, which uses photoexcitation to drive reactive oxygen species channels, utilizes a photochemical-electrochemical cascade reaction between donor and acceptor beads. This solves the problems of large-scale and high-cost detection equipment in existing technologies, and enables the detection of biomarkers with high sensitivity and low cost, especially the accurate quantitative analysis of miRNAs and proteins.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- CHONGQING UNIV
- Filing Date
- 2025-04-24
- Publication Date
- 2026-07-17
AI Technical Summary
Existing technologies for detecting tumor markers in the biomedical field suffer from problems such as insufficient sensitivity, high false positive rates, large equipment size, and high costs, especially for detecting biomarkers with minute changes, such as miRNA and protein in blood.
The kit for photoexcited electro-driven reactive oxygen species channels includes donor beads and acceptor beads. The donor beads generate singlet oxygen through laser irradiation, while the acceptor beads capture and generate an electrochemical signal at the electrode interface. Combined with probes of target biomarkers, it enables immobilized homogeneous electrochemical detection.
It achieves highly sensitive and low-cost biomarker detection, enabling rapid and accurate quantitative analysis in miniaturized devices, reducing false positive rates and improving detection repeatability and anti-interference capabilities.
Smart Images
Figure CN120314385B_ABST