A preparation device and process for pituitary posterior lobe injection

CN120421099BActive Publication Date: 2026-09-15CHINA RESOURCES SHUANGHE PHARMACEUTICAL (NANJING) CO LTD
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Patent Information

Application Number
CN202510552348.X
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2025-04-29
Publication Date
2026-09-15
Estimated Expiration
2045-04-29

AI Technical Summary

Technical Problem

[0004]上述垂体后叶注射液的制备粉碎装置,在启动电机,通过转动轴带动粉碎杆进行粉碎作业时,因长时间的摩擦,使转动轴和粉碎辊可能会因摩擦力发热,从而发热后的粉碎杆在进行粉碎作业时,容易导致垂体后叶中的生物活性成分降解,影响其生物活性,且会导致垂体后叶粘黏在粉碎设备上,难以掉落,从而会影响粉碎效率

Benefits of technology

(1)本发明通过设置冷却装置,当启动泵体时,能够使泵体将冷却箱中的冷却水进行吸出,通过连管、连接块排到上方的冷却板中,通过连接管使冷却水排到下方的冷却板中,且通过循环管的配合,使冷却水在冷却板中进行循环,从而通过冷却板能够对粉碎辊进行降温作业,解决了粉碎辊在长时间旋转,因摩擦可能会导致粉碎辊温度过高,导致物料损坏和粘黏在粉碎辊外壁的问题;且当转动杆进行旋转时,能够带动挤压块进行转动,通过斜面块和连接弹簧配合,能够带动冷却板在粉碎辊中进行来回移动,从而能够使冷却板中的冷却液进行晃动,使距离粉碎辊近的温度升高的冷却液和温度低的冷却液进行混合,使冷却液在冷却板中的温度保持一致,解决了冷却液在冷却板中的温度不一致,从而导致对粉碎辊的冷却效率下降的问题。

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Abstract

The application discloses a preparation device and process of pituitary posterior lobe injection, relates to the technical field of pituitary posterior lobe injection preparation, and the preparation device of the pituitary posterior lobe injection comprises a shell, a feeding cover is fixed to the top of the shell, a motor is fixed to the side wall of the shell, a rotating rod is fixed to the output end of the motor, and the rotating rod penetrates the side wall of the shell. The preparation device and process of the pituitary posterior lobe injection can suck out cooling water in the cooling box when the pump body is started, discharge the cooling water into the upper cooling plate through the connecting pipe and the connecting block, discharge the cooling water into the lower cooling plate through the connecting pipe, and make the cooling water circulate in the cooling plate through the cooperation of the circulating pipe, so that the cooling plate can be used for cooling the crushing roller, and the problems that the crushing roller is rotated for a long time, the temperature of the crushing roller is too high due to friction, and the material is damaged and adhered to the outer wall of the crushing roller are solved.
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Description

Technical Field

[0001] This invention relates to the field of preparation technology of posterior pituitary injection, specifically to an apparatus and process for preparing posterior pituitary injection. Background Technology

[0002] Posterior pituitary extract contains oxytocin and antidiuretic hormone. Antidiuretic hormone constricts blood vessels, raising blood pressure; it is also known as vasopressin. It is mainly used to treat diabetes insipidus and pulmonary hemorrhage. Oxytocin, also known as oxytocin, is a pituitary neurohormone secreted by giant cells in the supraoptic and paraventricular nuclei of the hypothalamus. Its molecular formula is C43H66N12O12S2, composed of nine amino acid residues, with two cysteine ​​residues forming a disulfide bond at positions 1 and 6. Its relative molecular mass is 1007.2, and its isoelectric point is 7.7. It is stable in acidic solvents and exists in the bloodstream as a free peptide. It is readily soluble in water, soluble in acetone, dilute acetic acid, and butanol, and slightly soluble in acetonitrile. Clinically, posterior pituitary extract is mainly used for inducing labor, postpartum hemostasis, and treating uterine atony during labor. In addition, posterior pituitary extract has a wide range of physiological functions, especially its effects on the central nervous system. As a pharmaceutical product, posterior pituitary extract is mainly extracted from the pituitary gland of animals.

[0003] Patent publication number CN117046554B discloses a posterior pituitary abscess pulverizing mechanism for preparing posterior pituitary abscess injection, relating to the pharmaceutical field. The mechanism includes a housing containing a pulverizing mechanism comprising a first motor and two rotating shafts. The housing has an inlet at the top and an outlet at the bottom. The rotating shafts are movably connected inside the housing, and pulverizing rods are mounted on the two shafts. These pulverizing rods crosswise pulverize the posterior pituitary abscess. The first motor is connected to one side of the housing and drives the rotating shafts to rotate. The posterior pituitary abscess pulverizing and drying integrated device also includes a constant temperature drying mechanism. This invention uses the pulverizing mechanism within the housing to cross-extract and pulverize the posterior pituitary abscess. The remaining material on the pulverizing rods is cleaned on the other side of the rotating shafts, effectively removing pulverized material adhering to the rods. Cleaning and pulverizing are performed simultaneously on one side, resulting in high efficiency.

[0004] In the aforementioned pulverizing device for preparing posterior pituitary injection, when the motor is started and the pulverizing rod is driven by the rotating shaft for pulverizing, the rotating shaft and pulverizing roller may heat up due to friction during prolonged operation. As a result, the heated pulverizing rod may degrade the bioactive components in the posterior pituitary during pulverizing, affecting its bioactivity. Furthermore, it may cause the posterior pituitary to stick to the pulverizing equipment and be difficult to remove, thus affecting the pulverizing efficiency. Summary of the Invention

[0005] To address the shortcomings of existing technologies, this invention provides an apparatus and process for preparing posterior pituitary injection, thus solving the problems mentioned in the background section.

[0006] To achieve the above objectives, the present invention provides the following technical solution: a device for preparing posterior pituitary injection, comprising a housing, a feed hood fixed to the top of the housing, a motor fixed to the side wall of the housing, a rotating rod fixed to the output end of the motor, the rotating rod penetrating the side wall of the housing and rotatably connected at the penetration point, a crushing roller fixed to the outer wall of the rotating rod, which, when the motor is started, causes the rotating rod to rotate, thereby driving the crushing roller to rotate, and the material can be crushed by the rotation of the crushing roller, the crushing roller penetrating the right side of the housing and rotatably connected at the penetration point, a cooling device for cooling the crushing roller is provided inside the crushing roller, an auxiliary device for preventing material from sticking to the outer wall of the crushing roller is provided inside the housing, and a pretreatment device for cutting the material is provided at the top of the crushing roller; The cooling device includes a cooling box, a cooling plate, a connecting pipe, a connecting block, a pump body, a connecting pipe, a circulation pipe, a guide rod, a connecting plate, an inclined block, a connecting spring, and a pressing block. The cooling box is fixed to the right side of the housing. The guide rod passes through the right side of the housing and is slidably connected at the point of penetration. The connecting plate is fixed to the end of the guide rod. One side of the connecting spring is fixed to the right side of the housing, and the other side of the connecting spring is fixed to the side wall of the connecting plate.

[0007] According to the above technical solution, the cooling plate is attached to the inner wall of the crushing roller. Two sets of cooling plates are arranged in the crushing roller, and the two sets of cooling plates are symmetrically arranged with the center line in the vertical direction of the crushing roller as the axis of symmetry. The two sets of cooling plates are connected by a connecting pipe. The connecting block is fixed to the side wall of the cooling plate, and the side of the connecting block away from the cooling plate is fixed to the side wall of the connecting plate. The pump body is fixed to the outer wall of the cooling tank. One end of the connecting pipe is fixed to the side wall of the pump body, and the other end of the connecting pipe is fixed to the outer wall of the upper connecting block. One end of the circulation pipe is fixed to the outer wall of the cooling tank, and the other end of the circulation pipe is fixed to the outer wall of the lower connecting block. By starting the pump body, the pump body can draw out the coolant in the cooling tank, so that the cooling water is discharged into the cooling plate through the connecting pipe. The cooling plate can cool the outer wall of the crushing roller.

[0008] According to the above technical solution, the extrusion block is fixed at the end of the rotating rod, and the inclined block is fixed on the side of the connecting plate near the housing. When the rotating rod rotates, it can drive the extrusion block to rotate. When the extrusion block rotates to contact the inclined surface of the inclined block, it can cause the extrusion block to press the inclined block to move, thereby driving the connecting plate to move, and causing the connecting block to drive the cooling plate to move.

[0009] According to the above technical solution, the auxiliary device includes an arc-shaped block, a trapezoidal block, a striking block, a transmission spring, a transmission disc, a connecting rod, a return spring, a disc, and a striking block. The arc-shaped block is fixed to the outer wall of the rotating rod, the striking block is slidably mounted on the inner side of the cooling plate, the trapezoidal block is fixed to the side of the striking block near the rotating rod, one side of the transmission spring is fixed to the outer wall of the trapezoidal block, and the other side of the transmission spring is fixed to the outer wall of the cooling plate. When the crushing roller rotates, the arc-shaped block can squeeze the inclined surface of the trapezoidal block, thereby causing the trapezoidal block to move upward. When the trapezoidal block moves upward, it can drive the striking block to move upward, causing the striking block to strike the inner wall of the crushing roller.

[0010] According to the above technical solution, the transmission disc is attached to the inner wall of the crushing roller, the connecting rod passes through the left side of the crushing roller and is slidably connected at the penetration point, and the right end of the connecting rod is fixed to the outer wall of the transmission disc. The side of the disc near the transmission disc is fixedly connected to the end point of the connecting rod. When the cooling plate moves away from the motor, the cooling plate can prevent the transmission disc from being squeezed. Because the return spring is in a compressed state, the return spring can drive the transmission disc to move, and the connecting rod can drive the disc to move, thereby causing the striking block to move back and forth on the crushing roller.

[0011] According to the above technical solution, one side of the reset spring is fixed to the outer wall of the transmission disk, the other side of the reset spring is fixed to the inner wall of the crushing roller, and the striking block is fixed to the side wall of the disk.

[0012] According to the above technical solution, the pretreatment device includes an L-shaped block, a long plate, a cutting blade, a rack, a gear, a rotating rod, and a flipping rod; the L-shaped block is fixed to the top of the connecting plate, the long plate is fixed to the end of the L-shaped block, the cutting blade is fixed to the side wall of the long plate, and the cutting blade penetrates through the feed hood, with a sliding connection at the penetration point; the rack is fixed to the side wall of the long plate, and when the connecting plate moves, it can drive the L-shaped block to move, so that the long plate drives the cutting blade to move back and forth in the feed hood.

[0013] According to the above technical solution, the rotating rod penetrates the outer wall of the feed hood and is rotatably connected at the penetration point. The gear is fixed to the outer wall of the rotating rod, and the gear meshes with the bottom of the rack. The flipping rod is fixed to the outer wall of the rotating rod. When the long plate moves back and forth, it can drive the rack to move back and forth on the gear, thereby causing the rack to drive the gear to rotate, causing the gear to drive the rotating rod to rotate, thereby causing the rotating rod to drive the flipping rod to rotate.

[0014] A process for preparing a posterior pituitary injection, based on the aforementioned apparatus for preparing a posterior pituitary injection, includes the following steps: S1. In preparing the posterior pituitary injection solution, the posterior pituitary lobes are first washed. After cleaning, the solution is then... The motor is started, which drives the rotating rod and crushing roller to rotate. The cleaned rear blades of the pendulum are added into the feed hood through the feed hood for crushing. S2. During the rotation of the crushing roller, open the sealing cover at the top of the cooling box, add cooling water to the cooling box, and start the pump to draw out the cooling water from the cooling box and discharge it into the cooling plate, which can cool down the heat generated by the friction of the crushing roller rotation. S3. When the rotating rod rotates, it can cause the extrusion block to extrude the inclined block. Through the cooperation of the connecting plate and the connecting spring, the cooling plate can reciprocate within the crushing roller.

[0015] This invention provides an apparatus and process for preparing a posterior pituitary injection solution. It has the following beneficial effects: (1) By setting up a cooling device, when the pump body is started, the pump body can draw out the cooling water in the cooling tank and discharge it to the upper cooling plate through the connecting pipe and connecting block. The cooling water is discharged to the lower cooling plate through the connecting pipe. With the cooperation of the circulation pipe, the cooling water circulates in the cooling plate. Thus, the cooling plate can cool the crushing roller. This solves the problem that the crushing roller may become too hot due to friction during long-term rotation, which may cause material damage and sticking to the outer wall of the crushing roller. When the rotating rod rotates, it can drive the extrusion block to rotate. With the cooperation of the inclined block and the connecting spring, the cooling plate can move back and forth in the crushing roller. This allows the coolant in the cooling plate to shake, so that the coolant with higher temperature near the crushing roller and the coolant with lower temperature can mix. This keeps the temperature of the coolant in the cooling plate consistent and solves the problem that the cooling efficiency of the crushing roller is reduced due to the inconsistent temperature of the coolant in the cooling plate.

[0016] (2) By setting an auxiliary device, when the connecting plate is far away from the motor, the cooling plate can prevent the transmission plate from pressing the transmission plate. With the cooperation of the reset spring, the disc can drive the striking block away from the motor, so that the striking block can move back and forth on the crushing roller, knocking the material between the crushing teeth on the crushing roller off, preventing too much material from sticking between the crushing teeth and affecting the crushing effect. When the crushing roller is rotating, the arc-shaped block can press the trapezoidal block. With the cooperation of the transmission spring, the striking block can knock back and forth on the inner wall of the crushing roller, thereby knocking the material stuck on the crushing roller loose, making it convenient for the striking block to knock the material off the crushing roller in the future.

[0017] (3) By setting up a pre-treatment device, when the connecting plate moves back and forth, the connecting plate can drive the L-shaped block to move back and forth, and the long plate can drive the cutting blade to move back and forth in the feed hood. Thus, the cutting blade can cut the material that is too large into small pieces when added to the feed hood, which solves the problem that the material is too large and it is inconvenient for the crushing roller to crush it later. When the long plate moves, the rack can move on the gear, which can drive the rotating rod to rotate, and the turning rod can rotate between the cutting blades. The turning rod can squeeze and turn the material between the cutting blades, which solves the problem that the material is blocked between the two sets of cutting blades after being cut in the cutting blades and is difficult to fall off. Attached Figure Description

[0018] Figure 1 This is a schematic diagram of the overall structure of the present invention; Figure 2 This is a schematic diagram of the internal structure of the housing of the present invention; Figure 3 This is a schematic cross-sectional view of the housing structure of the present invention; Figure 4 This is a partial structural diagram of the present invention; Figure 5 For the present invention Figure 3 Enlarged schematic diagram of structure A; Figure 6 This is a schematic diagram of the crushing roller structure of the present invention; Figure 7 This is a schematic cross-sectional view of the crushing roller structure of the present invention; Figure 8 This is a partial structural diagram of the present invention; Figure 9 This is a schematic diagram of the auxiliary device structure of the present invention; Figure 10 This is a schematic diagram of the pretreatment device of the present invention.

[0019] In the diagram: 1. Shell; 2. Feed hood; 3. Motor; 4. Rotating rod; 5. Crushing roller; 61. Cooling box; 62. Cooling plate; 63. Guide rod; 64. Connecting plate; 65. Connecting spring; 66. Connecting block; 67. Inclined block; 68. Pump body; 69. Connecting pipe; 610. Circulation pipe; 611. Extrusion block; 612. Connecting pipe; 71. Arc-shaped block; 72. Striking block; 73. Trapezoidal block; 74. Transmission spring; 75. Transmission disc; 76. Connecting rod; 77. Disc; 78. Return spring; 79. Striking block; 81. L-shaped block; 82. Long plate; 83. Cutting blade; 84. Rack; 85. Rotating rod; 86. Gear; 87. Flipping rod. Detailed Implementation

[0020] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0021] Please see Figure 1 one Figure 10 One embodiment of the present invention is: a preparation device for posterior pituitary injection, including a housing 1, a feed hood 2 fixed to the top of the housing 1, a motor 3 fixed to the side wall of the housing 1, a rotating rod 4 fixed to the output end of the motor 3, the rotating rod 4 passing through the side wall of the housing 1 and rotatably connected at the point of penetration, a crushing roller 5 fixed to the outer wall of the rotating rod 4, the crushing roller 5 passing through the right side of the housing 1 and rotatably connected at the point of penetration, two sets of motor 3 and rotating rod 4 are provided, and the two sets of motor 3 and rotating rod 4 are symmetrically arranged about the center line in the vertical direction of the housing 1 as the axis of symmetry, and two sets of crushing roller 5 are also provided, and the two sets of crushing roller 5 are respectively fixed to the outer wall of the two sets of rotating rod 4, and the crushing teeth on the crushing roller 5 are arranged in a cross pattern, and a cooling device for cooling the crushing roller 5 is provided inside the crushing roller 5; The cooling device includes a cooling box 61, a cooling plate 62, a connecting pipe 612, a connecting block 66, a pump body 68, a connecting pipe 69, a circulation pipe 610, a guide rod 63, a connecting plate 64, an inclined block 67, a connecting spring 65, and a pressing block 611. The cooling box 61 is fixed to the right side of the housing 1. The guide rod 63 passes through the right side of the housing 1 and is slidably connected at the point of penetration. The connecting plate 64 is fixed to the end of the guide rod 63. One side of the connecting spring 65 is fixed to the right side of the housing 1, and the other side of the connecting spring 65 is fixed to the side wall of the connecting plate 64. The cooling plate 62 is attached to the inner wall of the crushing roller 5. Two sets of cooling plates 62 are provided in the crushing roller 5, and the two sets of cooling plates 62 are symmetrically arranged about the center line of the crushing roller 5 in the vertical direction. The two sets of cooling plates 62 are connected by the connecting pipe 612. The connecting block 66 is fixed. On the side wall of the cooling plate 62, the connecting block 66 is connected to the cooling plate 62. The side of the connecting block 66 away from the cooling plate 62 is fixed to the side wall of the connecting plate 64. The pump body 68 is fixed to the outer wall of the cooling box 61 and is connected to the cooling box 61. One end of the connecting pipe 69 is fixed to the side wall of the pump body 68, and the other end of the connecting pipe 69 is fixed to the outer wall of the upper connecting block 66 and is connected to the upper connecting block 66. One end of the circulation pipe 610 is fixed to the outer wall of the cooling box 61, and the other end of the circulation pipe 610 is fixed to the outer wall of the lower connecting block 66 and is connected to the cooling box 61 and the connecting block 66. The circulation pipe 610 and the connecting pipe 69 are both plastic hoses. The extrusion block 611 is fixed to the end of the rotating rod 4. The inclined block 67 is fixed to the side of the connecting plate 64 near the housing 1.

[0022] When the pump body 68 is started, it can draw out the cooling water in the cooling tank 61 and discharge it into the upper cooling plate 62 through the connecting pipe 69 and the connecting block 66. The cooling water is discharged into the lower cooling plate 62 through the connecting pipe 612. With the cooperation of the circulation pipe 610, the cooling water circulates in the cooling plate 62. Thus, the cooling plate 62 can cool down the crushing roller 5, which solves the problem that the crushing roller 5 may become too hot due to friction during long-term rotation, resulting in material damage and sticking to the outer wall of the crushing roller 5. Furthermore, when the rotating rod 4 rotates, it can drive the extrusion block 611 to rotate. Through the cooperation of the inclined block 67 and the connecting spring 65, it can drive the cooling plate 62 to move back and forth in the crushing roller 5, thereby causing the coolant in the cooling plate 62 to slosh. This allows the coolant that is too close to the crushing roller 5 and has a higher temperature to mix with the coolant that has a lower temperature, so that the temperature of the coolant in the cooling plate 62 remains consistent. This solves the problem of inconsistent temperature of the coolant in the cooling plate 62, which leads to a decrease in the cooling efficiency of the crushing roller 5.

[0023] A preparation process for a posterior pituitary injection includes the following steps: S1. When preparing the posterior pituitary injection, the posterior pituitary axilla is first cleaned. After cleaning, the motor 3 is started to drive the rotating rod 4 and the crushing roller 5 to rotate. The cleaned posterior pituitary axilla is added into the feed hood 2 through the feed hood 2 for crushing. S2. During the rotation of the crushing roller 5, open the sealing cover at the top of the cooling box 61, add cooling water to the cooling box 61, and start the pump body 68 to draw out the cooling water in the cooling box 61 and discharge it into the cooling plate 62, which can cool down the heat generated by the rotation friction of the crushing roller 5. S3. When the rotating rod 4 is rotating, the extrusion block 611 can extrude the inclined block 67. Through the cooperation of the connecting plate 64 and the connecting spring 65, the cooling plate 62 can reciprocate within the crushing roller 5.

[0024] In this embodiment, during operation: when the pendulum rear leaf is added to the feed hood 2, it falls between the two sets of crushing rollers 5. The motor 3 is started, causing the rotating rod 4 to rotate the two sets of crushing rollers 5 inwards, thus enabling crushing. During crushing, the pump 68 can be activated to draw out the cooling water added to the cooling tank 61. The cooling water flows through the upper connecting block 66 into the upper cooling plate 62, and the coolant in the upper cooling plate 62 flows through the connecting pipe 612 into the lower cooling plate 62. The coolant then flows through the lower connecting block 66 into the circulation pipe 610, and is discharged back into the cooling tank 61 through the circulation pipe 610. The cooling water circulates in the cooling plate 62, and the cooling plate 62 adheres to the inner wall of the crushing roller 5, cooling the crushing roller 5. When the rotating rod 4 rotates, it drives the extrusion block 611 to rotate. When the round rod protruding from the right side of block 611 rotates to contact the inclined surface of inclined block 67, the pressing block 611 will press the inclined surface of inclined block 67, causing the inclined block 67 to be squeezed away from the motor 3. This allows the connecting plate 64 to drive the guide rod 63 to move out of the housing 1, stretching the connecting spring 65. When the connecting plate 64 moves, the connecting block 66 can drive the cooling plate 62 away from the motor 3. When the pressing block 611 rotates to a point where it is no longer in contact with the inclined surface of inclined block 67, the connecting spring 65 is in a stretched state, which allows the connecting spring 65 to drive the connecting plate 64 and the connecting block 66 to reset. This allows the connecting block 66 to drive the cooling plate 62 to reset. Through the back-and-forth movement of the cooling plate 62 in the crushing roller 5, the coolant in the cooling plate 62 can be shaken, mixing the coolant in the cooling plate 62, keeping the temperature of the coolant in the cooling plate 62 consistent, and maintaining a consistent cooling effect on the crushing roller 5.

[0025] Please see Figure 1 one Figure 10Based on the above embodiments, in another embodiment of the present invention, an auxiliary device is provided inside the housing 1 to prevent material from sticking to the outer wall of the crushing roller 5, and a pre-treatment device for cutting the material is provided on the top of the crushing roller 5. The auxiliary device includes an arc-shaped block 71, a trapezoidal block 73, a striking block 72, a transmission spring 74, a transmission disc 75, a connecting rod 76, a return spring 78, a disc 77, and a striking block 79; the arc-shaped block 71 is fixed to the outer wall of the rotating rod 4, the striking block 72 is slidably installed on the inner side of the cooling plate 62, and the trapezoidal block 73 is fixed on the side of the striking block 72 near the rotating rod 4. One side of the transmission spring 74 is fixed to the outer wall of the trapezoidal block 73, and the other side of the transmission spring 74 is fixed to the outer wall of the cooling plate 62. The transmission disc 75 is attached to the inner wall of the crushing roller 5. The connecting rod 76 passes through the left side of the crushing roller 5 and is slidably connected at the point of penetration. The right end of the connecting rod 76 is fixed to the outer wall of the transmission disc 75. The side of the disc 77 near the transmission disc 75 is fixedly connected to the end point of the connecting rod 76. One side of the return spring 78 is fixed to the outer wall of the transmission disc 75, and the other side of the return spring 78 is fixed to the inner wall of the crushing roller 5. The striking block 79 is fixed to the side wall of the disc 77.

[0026] When the connecting plate 64 is away from the motor 3, the cooling plate 62 can prevent the transmission plate 75 from being squeezed. With the cooperation of the return spring 78, the disc 77 can drive the striking block 79 away from the motor 3, so that the striking block 79 can move back and forth on the crushing roller 5, knocking the material between the crushing teeth on the crushing roller 5 off, preventing too much material from sticking between the crushing teeth and affecting the crushing effect. Furthermore, while the crushing roller 5 is rotating, the arc-shaped block 71 can squeeze the trapezoidal block 73. With the cooperation of the transmission spring 74, the striking block 72 can strike the inner wall of the crushing roller 5 back and forth, thereby loosening the material stuck on the crushing roller 5, making it easier for the subsequent striking block 79 to strike the material off the outer wall of the crushing roller 5.

[0027] The pretreatment device includes an L-shaped block 81, a long plate 82, a cutting blade 83, a rack 84, a gear 86, a rotating rod 85, and a flipping rod 87. The L-shaped block 81 is fixed to the top of the connecting plate 64, the long plate 82 is fixed to the end of the L-shaped block 81, the cutting blade 83 is fixed to the side wall of the long plate 82 and penetrates the feed hood 2, with a sliding connection at the penetration point, the rack 84 is fixed to the side wall of the long plate 82, the rotating rod 85 penetrates the outer wall of the feed hood 2 and is rotatably connected at the penetration point, the gear 86 is fixed to the outer wall of the rotating rod 85 and meshes with the bottom of the rack 84, and the flipping rod 87 is fixed to the outer wall of the rotating rod 85.

[0028] Four sets of cutting blades 83 are arranged in a linear array on the long plate 82. When the connecting plate 64 moves back and forth, it drives the L-shaped block 81 to move back and forth, which in turn drives the long plate 82 to move the cutting blades 83 back and forth within the feed hood 2. This allows the cutting blades 83 to cut oversized materials added to the feed hood 2, breaking down large pieces of the posterior part of the pituitary gland into smaller pieces, significantly reducing the time required for crushing. Smaller pieces are easier to crush, thus improving overall crushing efficiency.

[0029] Furthermore, when the long plate 82 moves, it causes the rack 84 to move on the gear 86, which in turn causes the gear 86 to drive the rotating rod 85 to rotate. This causes the flipping rod 87 to rotate between the cutting blades 83. The flipping rod 87 can squeeze and flip the material between the cutting blades 83, solving the problem of material getting stuck between the two sets of cutting blades 83 after being cut by the cutting blades 83 and difficult to fall off. In this embodiment, when the cooling plate 62 moves to the right, it stops pressing the transmission disc 75. Because the return spring 78 is compressed, it drives the transmission disc 75 to move to the right. This causes the transmission disc 75 to move the connecting rod 76 into the crushing roller 5, which in turn moves the disc 77 closer to the crushing roller 5. The disc 77 then drives the striking block 79 to move to the right. When the connecting plate 64 moves the connecting block 66 and the cooling plate 62 to the left, because the elastic coefficient of the connecting spring 65 is ten times that of the return spring 78, the cooling plate 62 presses the transmission disc 75 to the left, compressing the return spring 78. This causes the connecting rod 76 and the disc 77 to move to the left, and the striking block 79 to move to the left. The movement causes the striking block 79 to move back and forth within the crushing teeth of the crushing roller 5, knocking off the material adhering to the crushing teeth. Simultaneously, the arc-shaped block 71 rotates. When the arc-shaped block 71 rotates to press against the inclined surface of the trapezoidal block 73, the trapezoidal block 73 is pushed away from the rotating rod 4 by the pressure, compressing the transmission spring 74. This causes the trapezoidal block 73 to drive the striking block 72 to strike the inner wall of the crushing roller 5. When the arc-shaped block 71 rotates to a point where it no longer contacts the inclined surface of the trapezoidal block 73, the transmission spring 74 is compressed, causing the trapezoidal block 73 to drive the striking block 72 towards the rotating rod 4 for reset. Thus, the back-and-forth striking of the striking block 72 loosens the material adhering to the outer wall of the crushing roller 5. When the connecting plate 64 moves to the right, it can drive the L-shaped block 81 to move to the right, causing the L-shaped block 81 to drive the long plate 82 and the cutting blade 83 to move to the right. When the connecting plate 64 moves to the left, it can drive the L-shaped block 81 to drive the long plate 82 to move to the left, causing the cutting blade 83 to move to the left. By moving back and forth within the feed hood 2, the cutting blade 83 can cut relatively large pieces of the rear axle of the diaphragm into smaller pieces. When the long plate 82 moves back and forth, it can drive the rack 84 to move back and forth on the gear 86, causing the rack 84 to drive the gear 86 to rotate. When the gear 86 rotates, it can drive the rotating rod 85 to rotate, causing the rotating rod 85 to drive the flipping rod 87 to rotate between the two sets of cutting blades 83, thereby causing the flipping rod 87 to knock down the material blocked between the two sets of cutting blades 83.

[0030] Although embodiments of the invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A device for preparing a posterior pituitary injection, comprising a housing (1), characterized in that: The top of the housing (1) is fixed with a feed hood (2), the side wall of the housing (1) is fixed with a motor (3), the output end of the motor (3) is fixed with a rotating rod (4), the rotating rod (4) passes through the side wall of the housing (1) and is rotatably connected at the point of penetration, the outer wall of the rotating rod (4) is fixed with a crushing roller (5), the crushing roller (5) passes through the right side of the housing (1) and is rotatably connected at the point of penetration, a cooling device for cooling the crushing roller (5) is provided inside the crushing roller (5), an auxiliary device for preventing materials from sticking to the outer wall of the crushing roller (5) is provided inside the housing (1), and a pre-treatment device for cutting materials is provided at the top of the crushing roller (5); The cooling device includes a cooling box (61), a cooling plate (62), a connecting pipe (612), a connecting block (66), a pump body (68), a connecting pipe (69), a circulation pipe (610), a guide rod (63), a connecting plate (64), an inclined block (67), a connecting spring (65), and an extrusion block (611). The cooling box (61) is fixed to the right side of the housing (1). The guide rod (63) passes through the right side of the housing (1) and is slidably connected at the penetration point. The connecting plate (64) is fixed to the end point of the guide rod (63). One side of the connecting spring (65) is fixed to the right side of the housing (1), and the other side of the connecting spring (65) is fixed to the side wall of the connecting plate (64). The cooling plate (62) is attached to the inner wall of the crushing roller (5). Two sets of cooling plates (62) are provided in the crushing roller (5), and the two sets of cooling plates (62) are arranged in a certain way. The vertical centerline of the crushing roller (5) is symmetrically arranged along the axis of symmetry, and the two sets of cooling plates (62) are connected by a connecting pipe (612). The connecting block (66) is fixed to the side wall of the cooling plate (62), and the side of the connecting block (66) away from the cooling plate (62) is fixed to the side wall of the connecting plate (64). The pump body (68) is fixed to the outer wall of the cooling box (61). One end of the connecting pipe (69) is fixed to the side wall of the pump body (68), and the other end of the connecting pipe (69) is fixed to the outer wall of the upper connecting block (66). One end of the circulation pipe (610) is fixed to the outer wall of the cooling box (61), and the other end of the circulation pipe (610) is fixed to the outer wall of the lower connecting block (66). The extrusion block (611) is fixed to the end of the rotating rod (4), and the inclined block (67) is fixed to the side of the connecting plate (64) near the shell (1). The auxiliary device includes an arc-shaped block (71), a trapezoidal block (73), a striking block (72), a transmission spring (74), a transmission disc (75), a connecting rod (76), a return spring (78), a disc (77), and a striking block (79); the arc-shaped block (71) is fixed to the outer wall of the rotating rod (4), the striking block (72) is slidably mounted on the inner side of the cooling plate (62), the trapezoidal block (73) is fixed to the side of the striking block (72) near the rotating rod (4), one side of the transmission spring (74) is fixed to the outer wall of the trapezoidal block (73), and the other side of the transmission spring (74) is fixed to the outer wall of the trapezoidal block (73). On the outer wall of the cooling plate (62), the transmission disk (75) is attached to the inner wall of the crushing roller (5), the connecting rod (76) passes through the left side of the crushing roller (5) and is slidably connected at the passage, and the right end of the connecting rod (76) is fixed to the outer wall of the transmission disk (75), the side of the disc (77) near the transmission disk (75) is fixedly connected to the end point of the connecting rod (76), one side of the return spring (78) is fixed to the outer wall of the transmission disk (75), the other side of the return spring (78) is fixed to the inner wall of the crushing roller (5), and the striking block (79) is fixed to the side wall of the disc (77). The pretreatment device includes an L-shaped block (81), a long plate (82), a cutting blade (83), a rack (84), a gear (86), a rotating rod (85), and a flipping rod (87); the L-shaped block (81) is fixed to the top of the connecting plate (64), the long plate (82) is fixed to the end of the L-shaped block (81), the cutting blade (83) is fixed to the side wall of the long plate (82), and the cutting blade (83) penetrates the feed hood (2) and is slidably connected at the penetration point, and the rack (84) is fixed to the side wall of the long plate (82).

2. The apparatus for preparing posterior pituitary injection solution according to claim 1, characterized in that: The rotating rod (85) penetrates the outer wall of the feed hood (2) and is rotatably connected at the penetration point. The gear (86) is fixed on the outer wall of the rotating rod (85). The gear (86) meshes with the bottom of the rack (84). The flipping rod (87) is fixed on the outer wall of the rotating rod (85).

3. A preparation process for a posterior pituitary injection, based on the apparatus for preparing a posterior pituitary injection according to any one of claims 1-2, characterized in that, Includes the following steps: S1. When preparing the posterior pituitary injection, the posterior pituitary leaf taken is first cleaned. After cleaning, the motor (3) is started to drive the rotating rod (4) and the crushing roller (5) to rotate. The cleaned posterior pituitary leaf is added into the feed hood (2) through the feed hood (2) for crushing. S2. During the rotation of the crushing roller (5), open the sealing cover on the top of the cooling box (61), add cooling water to the cooling box (61), and by starting the pump body (68), the cooling water in the cooling box (61) can be sucked out and discharged into the cooling plate (62), which can cool down the heat generated by the rotation friction of the crushing roller (5). S3. When the rotating rod (4) is rotating, the extrusion block (611) can extrude the inclined block (67). Through the cooperation of the connecting plate (64) and the connecting spring (65), the cooling plate (62) can reciprocate within the crushing roller (5).

Citation Information

Patent Citations

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    CN117046554B

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