一种刻蚀工艺光刻转盘设计的转盘式扫描共聚焦系统

The rotary scanning confocal system, designed using an etching process photolithography rotary disk, solves the problems of high phototoxicity, slow scanning speed, and low acquisition efficiency of traditional confocal microscopes, enabling live cell imaging and efficient image acquisition, and improving system resolution.

CN120491296BActive Publication Date: 2026-07-17BEIJING NAXI OPTOELECTRONICS TECH CO LTD

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
BEIJING NAXI OPTOELECTRONICS TECH CO LTD
Filing Date
2025-05-15
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

Traditional confocal microscopes suffer from high phototoxicity, slow scanning speed, low acquisition efficiency, and are unable to perform live cell imaging.

Method used

The rotary scanning confocal system, designed using an etching process photolithography rotary disk, includes a laser source assembly, a microlens array homogenizing assembly, an excitation filter switching assembly, a dichroic mirror switching assembly, a field aperture assembly, a high-speed rotary pinhole assembly, a fluorescence channel beam splitting assembly, a relay system assembly, and a ten-position filter rotary wheel assembly. In particular, the etching process of the high-speed rotary pinhole assembly enables multi-laser wavelength compatibility, rapid switching, and efficient acquisition.

Benefits of technology

Significantly reduces sample phototoxicity, improves image acquisition efficiency, enables live cell imaging, enhances system resolution, and removes out-of-focus background.

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Abstract

本申请公开了一种刻蚀工艺光刻转盘设计的转盘式扫描共聚焦系统,通过对激光光源组件、微透镜阵列匀光组件、激发滤色片切换组件、二向色镜切换组件、视场光阑组件、高速转盘pinhole组件、荧光通道分光组件、中继系统组件、十位滤色片转轮组件的创新设计,特别是对高速转盘pinhole组件的刻蚀工艺的,解决了传统共聚焦显微镜光毒性高,采集效率低、无法进行活细胞成像的问题,克服了现有技术的缺陷。
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