一种基于文丘里效应的盲孔微腔室无空隙液体填充方法
By employing a contraction-type microchannel structure design and centrifugal force drive in a blind-hole microchamber, the Venturi effect is utilized to transform the gas-liquid two-phase flow into annular flow, solving the problem of bubble residue, improving the stability and efficiency of liquid filling, simplifying the operation process, and reducing costs.
CN120550873BActive Publication Date: 2026-07-17DALIAN UNIV OF TECH
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- DALIAN UNIV OF TECH
- Filing Date
- 2025-05-29
- Publication Date
- 2026-07-17
AI Technical Summary
Technical Problem
Residual air bubbles are a common problem during the liquid filling process of blind-hole microcavities. Existing methods are complex or costly, and affect the stability and success rate of liquid filling.
Method used
By adopting a contraction microchannel structure design based on the Venturi effect, the gas-liquid two-phase flow mode is controlled by optimizing the microchannel geometry. Centrifugal force is used to drive the liquid flow, transforming the gas-liquid two-phase flow into annular flow to discharge the gas, thus achieving void-free liquid filling.
Benefits of technology
It significantly improves the success rate and efficiency of liquid filling, simplifies the operation process, reduces costs, and improves the performance and reliability of microfluidic chips.
✦ Generated by Eureka AI based on patent content.
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Figure CN120550873B_ABST
Abstract
一种基于文丘里效应的盲孔微腔室的无空隙液体填充方法，属于微流控芯片技术领域。首先，设计微流控芯片的微通道结构，微通道结构由支通道、盲孔微腔室组成，等间隔设置在主通道的一侧，支通道为收缩式微通道，支通道尾端设有盲孔微腔室。其次，向微流控芯片储液池中注入液体，通过离心力驱动液体沿主通道流动，通过支通道进入各个盲孔微腔室，支通道的收缩结构使流体流速增加，促使气液两相流从包含大量气泡的泰勒流转变为气液分层的环形流。最后，完成液体填充后，盲孔微腔室内无气泡残留。本发明通过优化微通道几何形状调控气液两相流的流动模式，实现盲孔微腔室的无空隙液体填充；本发明无需复杂表面处理或外部施加力，显著提高了液体填充的成功率和效率。
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