一种FeCuZn纳米合金、比色生物传感器与应用

By constructing a colorimetric biosensor using FeCuZn nanoalloys, the problem of high cost of noble metal-based nanozymes has been solved, and high sensitivity and selectivity for the detection of glucose and glutathione have been achieved, showing broad prospects for practical applications.

CN120572016BActive Publication Date: 2026-07-17HAINAN MEDICAL UNIV

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
HAINAN MEDICAL UNIV
Filing Date
2025-06-20
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

In existing technologies, precious metal-based nanozymes are expensive, which limits their practical application, and existing methods for detecting glucose and glutathione are costly and complex to operate.

Method used

FeCuZn nanoalloys were prepared by a solvothermal method using three metal salts as precursors, citric acid as a reducing agent, Mo(CO)6 as an auxiliary reducing agent, polyvinylpyrrolidone as a stabilizer, and N,N-dimethylformamide as a solvent. A colorimetric biosensor was constructed for the detection of glucose and glutathione.

Benefits of technology

It achieves highly sensitive and selective detection of glucose and glutathione, avoids the consumption of precious metals, is low in cost, easy to operate, and suitable for practical applications in the medical and biological fields.

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Abstract

本发明提供一种FeCuZn纳米合金、比色生物传感器与应用,涉及生物传感器领域。本发明FeCuZn纳米合金通过溶剂热法制备,使用三种金属盐作为前驱体,柠檬酸作为还原剂,Mo(CO)6作为辅助还原剂,聚乙烯吡咯烷酮作为稳定剂,N,N‑二甲基甲酰胺作为溶剂;所述金属盐由铁盐、铜盐和锌盐组成。本发明制备FeCuZn纳米合金,属于一种新型的多金属纳米酶,避免了贵金属的消耗,同时具有与天然过氧化氢酶相似的催化特性;所构建的传感器对葡萄糖和谷胱甘肽具有优异的检测性能,并具有成本低廉、操作简便和检测快速的优势,表明其在医学和生物学等实际生产领域的应用前景广阔。
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