一种抗菌烧伤凝胶及其制备方法
By introducing modified hydroxyapatite nanorods into the antibacterial burn gel, the stability problem caused by silver ion precipitation was solved, the antibacterial properties and biocompatibility of the gel were improved, and more efficient burn wound repair was achieved.
CN120585737BActive Publication Date: 2026-07-17ROOSIN MEDICAL CO LTD
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- ROOSIN MEDICAL CO LTD
- Filing Date
- 2025-06-30
- Publication Date
- 2026-07-17
AI Technical Summary
Technical Problem
Existing silver-containing antibacterial burn gels have poor storage stability, and silver ions are prone to precipitation, leading to a decrease in antibacterial properties.
Method used
By introducing and modifying hydroxyapatite nanorods, their unique structure and properties are utilized to form strong coordination bonds that bind with silver ions, constructing a three-dimensional network that prevents silver ion aggregation while enhancing biocompatibility and heat dissipation.
Benefits of technology
It improves the stability and antibacterial properties of the gel, enhances biocompatibility and heat dissipation, and provides a more efficient and safer solution for the antibacterial and repair of burn wounds.
✦ Generated by Eureka AI based on patent content.
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Figure CN120585737B_ABST
Abstract
本发明涉及烧伤凝胶技术领域，尤其涉及一种抗菌烧伤凝胶及其制备方法，制备方法包括如下步骤：将卡波姆分散于水中，静置溶胀，得到初级凝胶基质；对初级凝胶基质进行搅拌后，依次加入乳化硅油、乙醇、乙二胺四乙酸二钠溶液和乳化剂，搅拌，得到混合物A；在所述混合物A中加入银盐与改性羟基磷灰石纳米棒，搅拌，得到混合物B；将混合物B的pH值调节至6.5‑7.5，得到抗菌烧伤凝胶。本发明提引入银盐来赋予烧伤凝胶优异的抗菌性能；引入羟基磷灰石纳米棒，不仅解决了银离子沉淀导致抗菌性能下降的问题，还同步增强了凝胶的生物相容性与散热效果，为烧伤创面的抗菌与修复提供更高效、安全的解决方案。
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Citation Information
Patent Citations
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