tRF-Val-TAC-022在肺癌淋巴结转移诊断中的应用

By detecting the expression level of the biomarker tRF-Val-TAC-022, the challenge of early diagnosis of lymph node metastasis in lung cancer has been solved, enabling rapid and accurate diagnosis and improving the selectivity of treatment options.

CN120591405BActive Publication Date: 2026-07-17JIANGSU CANCER HOSPITAL
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
JIANGSU CANCER HOSPITAL
Filing Date
2025-06-25
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

Current technology lacks specific methods for early diagnosis of lymph node metastasis in lung cancer, resulting in some patients developing lymph node metastasis when the tumor is still small, making it impossible to adjust the surgical approach in advance and affecting the treatment outcome.

Method used

Using the biomarker tRF-Val-TAC-022, we detected its expression level in the serum of lung cancer patients. Its significantly high expression in patients with positive lymph node metastasis was used as a biomarker for early diagnosis of lung cancer lymph node metastasis, providing a rapid and accurate diagnostic method.

Benefits of technology

It enables early and rapid diagnosis of lymph node metastasis in lung cancer, improving diagnostic accuracy and sensitivity, and helping clinicians select appropriate treatment options.

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Abstract

本发明涉及分子生物学技术领域,公开了生物标志物tRF‑Val‑TAC‑022在制备肺癌淋巴结转移诊断产品中的应用。该生物标志物tRF‑Val‑TAC‑022在发生肺癌淋巴结转移患者血清中的表达水平显著高于没有淋巴结转移的肺癌患者,可以作为肺癌淋巴结转移诊断的生物标志物,灵敏度高,特异度高,利用该分子可以简单、快捷地进行肺癌淋巴结转移的早期诊断。
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