A planar microfluidic reagent disc and processing device

Abstract

This invention relates to the technical field of microfluidic reagent trays and their processing, and particularly to a flat microfluidic reagent tray and processing device, comprising a central tray body and two sets of side plates, the two sets of side plates being respectively installed on the upper and lower parts of the central tray body, with an inlet provided on the upper side plate; it also includes a check valve assembly, a diluent chamber, a quantitative volume chamber, a mixing chamber, a blood storage chamber, a separation chamber, a first orifice, and a second orifice. The diluent chamber is located in the middle of the central tray body, and the quantitative volume chamber and the mixing chamber are both located on the central tray body, with the quantitative volume chamber surrounding the diluent chamber and the mixing chamber surrounding the quantitative volume chamber. The diluent chamber, quantitative volume chamber, and mixing chamber are connected to each other through microfluidic channels; this facilitates the separate storage of liquids in multiple sets of second orifices, avoiding cross-contamination, and achieving an integrated effect of automatic raw material delivery and automatic processing of the reagent tray, thus improving processing efficiency.

Description

Technical Field

[0001] This invention relates to the technical field of microfluidic reagent trays and their processing, and in particular to a flat microfluidic reagent tray and its processing device. Background Technology

[0002] As a key component of microfluidic systems, microfluidic reagent trays play a crucial role in holding reagents, providing reaction sites, and guiding fluid flow. In biomedical testing, microfluidic reagent trays can integrate multiple detection reagents and reaction units, enabling the simultaneous detection of multiple biomarkers, significantly improving throughput and efficiency.

[0003] Currently, in existing microfluidic reagent trays, such as the patent with authorization announcement number CN108786944B, this invention belongs to the field of microfluidic chip technology and discloses a control valve, which is set on the microfluidic channel (2) of the microfluidic chip. The microfluidic chip includes a chip body (1), and the control valve includes a valve cavity (3) and a reversible water absorption mechanism (4), which is set in the valve cavity (3). A centrifugal microfluidic chip is also disclosed, which includes a chip body (1), an inlet (7), a reaction chamber (8), a microfluidic channel (2), and a control valve set between the inlet (7) and the reaction chamber (8).

[0004] In the use of existing microfluidic chips, it has been found that the chips are usually set up with a single row of wells, and the wells are directly connected to each other. The plasma mixed with the reagent in the wells is prone to backflow when affected by the exhaust, which leads to contamination between wells. Ultimately, the measurement results are inaccurate due to reagent contamination. Summary of the Invention

[0005] To solve the above-mentioned technical problems, the present invention provides a flat microfluidic reagent tray and processing device that, due to the function of the anti-reverse component, prevents the mixture of reagent and reagent in the second well from flowing back out, thereby facilitating the separate storage of liquids in multiple sets of second wells and avoiding cross-contamination. This achieves an integrated effect of automatic raw material conveying and automatic processing of the reagent tray, improving processing efficiency.

[0006] This invention discloses a flat microfluidic reagent tray, comprising a central tray body and two sets of side plates, the two sets of side plates being respectively installed on the upper and lower parts of the central tray body, with the upper side plate having an inlet; it also includes a check valve assembly, a diluent chamber, a quantitative volume chamber, a mixing chamber, a blood storage chamber, a separation chamber, first orifices, and second orifices. The diluent chamber is located in the center of the central tray body. The quantitative volume chamber and the mixing chamber are both located on the central tray body, with the quantitative volume chamber surrounding the diluent chamber and the mixing chamber surrounding the quantitative volume chamber. The diluent chamber, quantitative volume chamber, and mixing chamber are connected to each other via microfluidic channels. The blood storage chamber and the separation chamber are both located on the central tray body, and the blood storage chamber and the separation chamber are connected via microfluidic channels. Multiple sets of first orifices and multiple sets of second orifices are circumferentially arranged on the central tray body. The multiple sets of first orifices are connected to the mixing chamber via microfluidic channels, and the multiple sets of second orifices are connected to the check valve assembly via microfluidic channels. The device is connected to multiple sets of first wells. Diluent is added to the interior of the central disc through the inlet, and collected blood is added to the blood storage chamber through the inlet. Then, the central disc and side plates are placed in a centrifuge. With centrifugation, the red blood cells in the blood in the blood storage chamber are centrifuged and separated and flow into the separation chamber for storage. The diluent in the central disc first flows into the quantitative volume chamber, and then flows into the mixing chamber. The plasma remaining in the blood storage chamber after centrifugation flows into the mixing chamber and mixes with the diluent. Subsequently, the mixed liquid flows into multiple sets of first wells. The mixed liquid in multiple sets of first wells enters multiple sets of second wells through the check valve component and mixes with the reagent. Due to the function of the check valve component, the mixed liquid with the reagent in the second wells will not flow back out, thus facilitating the separate storage of the liquid in multiple sets of second wells and avoiding cross-contamination.

[0007] Preferably, the anti-reverse component includes a tank, a connecting channel, and rubber plugs. Multiple tanks are disposed on the central disc. The front ends of the multiple tanks are connected to multiple first holes and multiple second holes through multiple connecting channels. Multiple rubber plugs are embedded inside the multiple tanks. In the initial state, the front ends of the rubber plugs seal the front opening of the tank, thereby closing the connection between the first hole and the connecting channel. When the central disc rotates centrifugally, the multiple rubber plugs are compressed and shortened by centrifugal force. At this time, the front ends of the rubber plugs open the front opening of the tank, thus facilitating the flow of the mixture in the first hole into the second hole through the connecting channel. After centrifugation, the rubber plugs return to their original shape and seal the front end of the tank again, thereby preventing the liquid in the second hole from flowing back through the connecting channel.

[0008] Preferably, a flat microfluidic reagent tray processing device includes a power unit, a feeding device, a processing table, a laser cutting device, a suction cup, a storage cylinder, and elastic limiting plates. The processing table has multiple sets of positioning holes circumferentially. The laser cutting device is mounted on a mobile device, which is used to adjust the movement of the laser cutting device in different directions. The suction cup is connected to an external suction device and is mounted on the power unit. The power unit moves the suction cup and drives the rotation of the processing table. The storage cylinder is mounted on top of the power unit. Multiple sets of elastic limiting plates are located at the bottom opening of the storage cylinder. The feeding device is located below the processing table and is used to feed and transport the processed reagent trays. The raw materials for the reagent trays to be processed are stacked inside the storage cylinder. The bottom layer of raw materials is supported and limited by the multiple sets of elastic limiting plates. When the power unit moves the suction cup upwards, the suction cup and the bottom layer of raw materials are supported and limited. The raw material is brought into contact with the bottom. An external suction device draws air into the suction cup, causing it to pick up the material. A power unit then moves the suction cup downwards and flips it downwards, allowing it to transport the picked-up material to the corresponding positioning hole on the processing table. When the power unit moves the suction cup upwards to pick up material, it simultaneously rotates the processing table one station. When the power unit moves the suction cup downwards to release material, the processing table stops rotating and is fixed. At this point, the previous raw material to be processed is moved to the bottom of the laser cutting equipment. Through the cooperation of the laser cutting equipment and the moving equipment, the raw material is cut and shaped. This process repeats, achieving an integrated effect of automatic material transport and automatic processing, improving processing efficiency. The mechanical structure enables transmission between equipment movements, offering advantages such as fast response, low cost, strong environmental adaptability, strong anti-interference ability, and low maintenance difficulty.

[0009] Preferably, the power unit includes a transmission device, a base, a bracket, a support platform, a telescopic rod, a first spring, gears, a rack, a lead screw, and a motor. The processing table is rotatably mounted on the base, the bracket is slidably mounted on the base, both ends of the support platform are rotatably mounted on the bracket, the telescopic rod is mounted on the outer wall of the support platform, the suction cup is mounted on the end of the telescopic rod, the first spring is fitted onto the telescopic rod, two sets of gears are respectively mounted on the rotating ends of the support platform, a rack is provided on the base to mesh with the two sets of gears, the lead screw is rotatably mounted on the base, the bracket is screwed onto the lead screw, the motor is mounted on the base, the output end of the motor is connected to the lead screw, and a transmission device is provided at the bottom of the lead screw to drive the rotation of the processing table; the motor drives the lead screw to rotate, causing the lead screw to drive the bracket to move up and down, and the bracket to move up and down, driving the support platform to move up and down; when the two sets of gears mesh with the two sets of racks, the support platform flips, realizing that the suction cup moves up and down while flipping towards picking up or unloading materials, improving work efficiency.

[0010] Preferably, the transmission device includes a coupling, a rotating shaft, sprockets, and a chain. The bottom end of the lead screw is connected to the top end of the rotating shaft via the coupling. The bottom end of the rotating shaft is rotatably mounted on a base. The first set of sprockets is mounted on the rotating shaft via a first one-way bearing, and the second set of sprockets is mounted on the processing table. The two sets of sprockets are driven by a chain. When the lead screw rotates and drives the support to move upward, the lead screw drives the rotating shaft to rotate counterclockwise. The rotating shaft drives the sprockets to rotate counterclockwise via the first one-way bearing, thereby causing the processing table to rotate counterclockwise to transport the reagent tray. When the lead screw rotates and drives the support to move downward, the lead screw drives the rotating shaft to rotate clockwise. At this time, the rotating shaft cannot drive the sprockets to rotate via the first one-way bearing, thereby keeping the processing table stationary so that the suction cup can place the raw material into the positioning hole.

[0011] Preferably, the assembly also includes a frustum, a connecting arm, a push rod, a first brake pad, and a tension spring. The frustum is mounted on the rotating shaft via a second one-way bearing. The connecting arm is rotatably mounted between the frustum and the push rod. The push rod is slidably mounted on the base, with its end connected to the first brake pad. The tension spring is mounted between the base and the push rod. After the rotating shaft rotates clockwise, it drives the frustum to rotate via the second one-way bearing. After the frustum rotates, it pushes the push rod via the connecting arm, causing the push rod to slide and push the first brake pad to press the machining table, thereby fixing the rotation of the machining table. By setting a coupling, it is convenient for the lead screw to continue rotating clockwise. When the lead screw rotates counterclockwise, the rotating shaft will not drive the frustum to rotate in the opposite direction and reset via the second one-way bearing. At this time, the tension spring provides tension to the push rod to move and reset the first brake pad.

[0012] Preferably, the feeding device includes a cylinder, a support member, a lifting rod, an inclined block, and a pushing block. The cylinder is mounted on a base, the support member is mounted on the moving end of the cylinder, the lifting rod is rotatably mounted on the support member, and a torsion spring is provided at the rotation point between the lifting rod and the support member. A limit member is provided on the support member to limit the rotation of the lifting rod. The inclined block is provided on the outer wall of the lifting rod, and multiple sets of pushing blocks are provided on the processing table, with each set of pushing blocks matching the position of a set of positioning holes. When the processed reagent tray moves above the lifting rod, the cylinder drives the support member to move upward, causing the support member to drive the lifting rod to move upward and push the processed reagent tray upward out of the positioning hole. As the lifting rod continues to move upward, the inclined block contacts the pushing block, causing the lifting rod to rotate and tilt to one side, thereby pushing the reagent tray to one side for feeding.

[0013] Preferably, it also includes a guide post and a second spring. The guide post is slidably mounted on the push rod, and the end of the guide post is connected to the first brake pad. The second spring is mounted on the guide post. By setting the guide post and the second spring, the buffering effect between the push rod and the first brake pad is improved, and the pressing force of the first brake pad on the processing table is increased.

[0014] Preferably, it also includes a second brake pad, which is disposed on the outer wall of the bracket and is interference-fitted with the rotating end of the support platform; when the support platform is flipped up or down into position, the second brake pad is used to press and brake the support platform, thereby improving the orientation stability of the support platform.

[0015] Preferably, it also includes a conveying trough, which is located on the side of the processing table; this improves the convenience of collecting and conveying the processed reagent tray.

[0016] Compared with the prior art, the beneficial effects of the present invention are as follows: due to the function of the anti-reverse component, the mixture of reagent in the second well position will not flow back out, thereby facilitating the separate storage of liquids in multiple sets of second well positions and avoiding cross-contamination. Attached Figure Description

[0017] Figure 1 This is a schematic diagram of the isometric structure of the flat microfluidic reagent disk of the present invention; Figure 2 This is an isometric structural diagram showing the connection between the central disc and the diluent chamber, etc. Figure 3 This is a partial isometric structural diagram showing the connection between the central disc and the side plates, etc. Figure 4 This is a partial isometric structural diagram showing the connection between the second hole and the connecting flow channel, etc. Figure 5 This is an isometric structural diagram showing the connection between the machining table and the base, etc. Figure 6 This is a partial isometric structural diagram of the connection between the storage cylinder and the elastic limiting plate, etc. Figure 7 This is a partial isometric structural diagram of the connection between the bracket and the support platform, etc. Figure 8 This is an isometric structural diagram of the connection between the lead screw and the motor, etc. Figure 9 This is a partial isometric structural diagram of the connection between the sprocket and the chain, etc. Figure 10 This is a partial isometric structural diagram of the connection between the coupling and the shaft, etc. Figure 11 This is a partial isometric structural diagram showing the connection between the support components and the lifting rod, etc. Figure 12 This is a partial isometric structural diagram showing the connection between the lifting rod and the inclined block, etc. Figure 13 This is a partial isometric structural diagram showing the connection between the first brake pad and the guide post, etc.

[0018] The attached diagram shows the following labels: 101, central disc; 102, diluent chamber; 103, quantitative volume chamber; 104, mixing chamber; 105, blood storage chamber; 106, separation chamber; 107, first orifice; 108, second orifice; 109, side plate; 201, tank; 202, connecting channel; 203, rubber stopper; 301, processing table; 302, laser cutting equipment; 303, suction cup; 304, storage cylinder; 305, elastic limiting plate; 401, base; 402, bracket; 403, support platform; 404. Telescopic rod; 405, First spring; 406, Gear; 407, Rack; 408, Lead screw; 409, Motor; 501, Coupling; 502, Shaft; 503, Sprocket; 504, Chain; 601, Frustum; 602, Connecting arm; 603, Push rod; 604, First brake pad; 605, Tension spring; 701, Cylinder; 702, Support; 703, Lifting rod; 704, Inclined block; 705, Push block; 801, Guide column; 802, Second spring; 901, Second brake pad; 1001, Conveying trough. Detailed Implementation

[0019] To facilitate understanding of the present invention, a more complete description will be given below with reference to the accompanying drawings. The present invention can be implemented in many different forms and is not limited to the embodiments described herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete. Example 1

[0020] A flat microfluidic reagent tray of the present invention, such as Figures 1 to 4 As shown, the device includes a central disc 101 and two sets of side plates 109, which are respectively installed on the upper and lower parts of the central disc 101. The upper side plate 109 is provided with an inlet. It also includes a check valve assembly, a diluent chamber 102, a quantitative volume chamber 103, a mixing chamber 104, a blood storage chamber 105, a separation chamber 106, a first port 107, and a second port 108. The diluent chamber 102 is located in the middle of the central disc 101. The quantitative volume chamber 103 and the mixing chamber 104 are both located on the central disc 101. The quantitative volume chamber 103 is located around the diluent chamber 102. The chamber 104 is located around the quantitative volume chamber 103. The diluent chamber 102, the quantitative volume chamber 103, and the mixing chamber 104 are connected by microfluidic channels. The blood storage chamber 105 and the separation chamber 106 are both located on the central disc 101. The blood storage chamber 105 and the separation chamber 106 are connected by microfluidic channels. Multiple sets of first orifices 107 and multiple sets of second orifices 108 are circumferentially located on the central disc 101. The multiple sets of first orifices 107 are connected to the mixing chamber 104 by microfluidic channels, and the multiple sets of second orifices 108 are connected to the multiple sets of first orifices 107 by anti-reverse components. The anti-reverse component includes a groove 201, a connecting channel 202, and a rubber plug 203. Multiple sets of grooves 201 are all arranged on the central disc 101. The front ends of the multiple sets of grooves 201 are connected to multiple sets of first holes 107 and multiple sets of second holes 108 through multiple sets of connecting channels 202. Multiple sets of rubber plugs 203 are respectively embedded inside the multiple sets of grooves 201. In this embodiment, the diluent is added to the central disc 101 through the inlet, and the collected blood is added to the blood storage chamber 105 through the inlet. Then, the central disc 101 and side plate 109 are placed in a centrifuge. During centrifugation, the red blood cells in the blood storage chamber 105 are separated and flow into the separation chamber 106 for storage. The diluent in the central disc 101 first flows into the quantitative volume chamber 103, and then flows into the mixing chamber 104. The remaining plasma in the blood storage chamber 105 after centrifugation flows into the mixing chamber 104 and mixes with the diluent. The mixed liquid then flows into multiple sets of first wells 107. The mixture in the multiple sets of first wells 107 passes through a check valve component into multiple sets of second wells 108 to mix with reagents. Because... The anti-backflow component prevents the mixture in the second orifice 108 from flowing back out, thus facilitating the separate storage of liquids in multiple sets of second orifices 108 and avoiding cross-contamination. Initially, the front end of the rubber stopper 203 seals the front opening of the tank 201, closing the connection between the first orifice 107 and the connecting channel 202. When the central disc 101 rotates centrifugally, the multiple rubber stoppers 203 are compressed and shortened by centrifugal force. At this time, the front end of the rubber stopper 203 opens the front opening of the tank 201, allowing the mixture in the first orifice 107 to flow into the second orifice 108 through the connecting channel 202. After centrifugation, the rubber stopper 203 returns to its original shape and seals the front end of the tank 201 again, thus preventing the liquid in the second orifice 108 from flowing back through the connecting channel 202. Example 2

[0021] Based on Example 1, the present invention provides a flat microfluidic reagent tray processing device, such as... Figures 5 to 13As shown, the device includes a power unit, a feeding device, a processing table 301, a laser cutting device 302, a suction cup 303, a storage cylinder 304, and elastic limiting plates 305. The processing table 301 has multiple sets of positioning holes in the circumferential direction. The laser cutting device 302 is mounted on a mobile device, which is used to drive the laser cutting device 302 to move and adjust in different directions. The suction cup 303 is connected to an external suction device and is mounted on the power unit. The power unit is used to drive the suction cup 303 to move and to drive the rotation of the processing table 301. The storage cylinder 304 is mounted on the upper part of the power unit. Multiple sets of elastic limiting plates 305 are all set at the bottom opening of the storage cylinder 304. The feeding device is located below the processing table 301 and is used to feed and transport the processed reagent tray. The power unit includes a transmission device, a base 401, a bracket 402, a support platform 403, a telescopic rod 404, a first spring 405, a gear 406, a rack 407, a lead screw 408, and a motor 409. The processing table 301 is rotatably mounted on the base 401. The bracket 402 is slidably mounted on the base 401. Both ends of the support platform 403 are rotatably mounted on the bracket 402. The telescopic rod 404 is mounted on the outer wall of the support platform 403. A suction cup 303 is mounted on the end of the telescopic rod 404. The first spring 405... Spring 405 is installed on telescopic rod 404. Two sets of gears 406 are installed on the rotating ends of the support table 403 on both sides. A rack 407 that meshes with the two sets of gears 406 is provided on the base 401. Lead screw 408 is rotatably installed on the base 401. Bracket 402 is screwed onto lead screw 408. Motor 409 is installed on base 401. The output end of motor 409 is connected to lead screw 408. A transmission device is provided at the bottom of lead screw 408. The transmission device is used to drive the rotation of processing table 301. It also includes a frustum 601, a connecting arm 602, a push rod 603, a first brake pad 604, and a tension spring 605. The frustum 601 is mounted on the rotating shaft 502 via a second one-way bearing. The connecting arm 602 is rotatably mounted between the frustum 601 and the push rod 603. The push rod 603 is slidably mounted on the base 401. The end of the push rod 603 is connected to the first brake pad 604. The tension spring 605 is mounted between the base 401 and the push rod 603. It also includes a guide post 801 and a second spring 802. The guide post 801 is slidably mounted on the push rod 603. The end of the guide post 801 is connected to the first brake pad 604. The second spring 802 is mounted on the guide post 801. It also includes a second brake pad 901, which is disposed on the outer side wall of the bracket 402 and is interference-fitted with the rotating end of the support platform 403; It also includes a conveyor trough 1001, which is located on the side of the processing table 301; In this embodiment, the reagent tray materials to be processed are stacked inside the storage cylinder 304. Multiple sets of elastic limiting plates 305 support and limit the bottom layer of materials. When the power device drives the suction cup 303 upward, the suction cup 303 contacts the bottom of the bottom layer of materials. An external suction device draws air into the suction cup 303, causing it to pick up the materials. Subsequently, the power device drives the suction cup 303 downward and flips it downward, allowing it to transport the picked-up materials downward and place them on the corresponding positioning hole on the processing table 301. When the power device drives the suction cup 303 upward to pick up materials, it simultaneously rotates the processing table 301 one station. When the power device drives the suction cup 303 downward to release materials, the processing table 301 stops rotating and is fixed. At this time, the previous material to be processed is moved and transported below the laser cutting equipment 302. The laser cutting equipment 302, in cooperation with the mobile equipment, achieves the cutting of the materials. Cutting and shaping; motor 409 drives lead screw 408 to rotate, causing lead screw 408 to drive bracket 402 to move up and down. After bracket 402 moves up and down, it drives support platform 403 to move up and down. When two sets of gears 406 mesh with two sets of racks 407, support platform 403 flips, realizing that suction cup 303 moves up and down while flipping to face the material picking or unloading direction; after rotating the rotating shaft 502 clockwise, it drives the frustum 601 to rotate through the second one-way bearing. After the frustum 601 rotates, it drives the connecting arm to rotate. Push rod 603 is pushed by 602, causing it to slide and push the first brake pad 604 to press the processing table 301, thereby fixing the rotation of the processing table 301. By setting the coupling 501, the lead screw 408 can continue to rotate clockwise. When the lead screw 408 rotates counterclockwise, the rotating shaft 502 will not drive the frustum 601 to rotate in the opposite direction and reset through the second one-way bearing. At this time, the tension spring 605 provides tension to the push rod 603 to move the first brake pad 604 to reset. Example 3

[0022] Based on Example 1, the present invention provides a flat microfluidic reagent tray processing device, such as... Figures 5 to 13 As shown, the transmission device includes a coupling 501, a rotating shaft 502, a sprocket 503, and a chain 504. The bottom end of the lead screw 408 is connected to the top end of the rotating shaft 502 through the coupling 501. The bottom end of the rotating shaft 502 is rotatably mounted on the base 401. The first set of sprockets 503 is mounted on the rotating shaft 502 through a first one-way bearing. The second set of sprockets 503 is mounted on the processing table 301. The two sets of sprockets 503 are driven by the chain 504. The feeding device includes a cylinder 701, a support 702, a lifting rod 703, an inclined block 704, and a pushing block 705. The cylinder 701 is mounted on the base 401, the support 702 is mounted on the moving end of the cylinder 701, the lifting rod 703 is rotatably mounted on the support 702, and a torsion spring is provided at the rotation point of the lifting rod 703 and the support 702. A limiter is provided on the support 702 to limit the rotation of the lifting rod 703. The inclined block 704 is provided on the outer wall of the lifting rod 703. Multiple sets of pushing blocks 705 are all provided on the processing table 301, and the positions of the multiple sets of pushing blocks 705 are respectively matched with the positions of multiple sets of positioning holes. When the lead screw 408 rotates to drive the bracket 402 to move upward, the lead screw 408 drives the rotating shaft 502 to rotate counterclockwise. The rotating shaft 502 drives the chain through the first one-way bearing. Wheel 503 rotates counterclockwise, causing processing table 301 to rotate counterclockwise to transport the reagent tray. When lead screw 408 rotates and drives bracket 402 to move downward, lead screw 408 drives shaft 502 to rotate clockwise. At this time, shaft 502 cannot drive sprocket 503 to rotate through the first one-way bearing, thus keeping processing table 301 stationary so that suction cup 303 can put raw material into positioning hole. When the processed reagent tray moves above lifting rod 703, cylinder 701 drives support 702 to move upward, causing support 702 to drive lifting rod 703 to move upward and push the processed reagent tray upward out of positioning hole. As lifting rod 703 moves upward, inclined block 704 contacts push block 705, causing lifting rod 703 to rotate and tilt to one side, thus pushing reagent tray to one side for feeding.

[0023] The main functions achieved by this invention are: Due to the function of the anti-reverse component, the mixture of reagent and liquid in the second well 108 will not flow back out, thus facilitating the separate storage of liquids in multiple sets of second wells 108 and avoiding cross-contamination. It achieves the integrated effect of automatic material feeding and automatic processing of reagent trays, improving processing efficiency. By adopting a mechanical structure to realize the transmission between equipment actions, it has the advantages of fast response, low cost, strong environmental adaptability, strong anti-interference ability and low maintenance difficulty.

[0024] The laser cutting device 302, motor 409 and cylinder 701 of the flat microfluidic reagent tray and processing device of the present invention are commercially available. Technical personnel in this industry only need to install and operate them according to the accompanying instruction manual, without requiring any creative work from those skilled in the art.

[0025] The above description is only a preferred embodiment of the present invention. It should be noted that for those skilled in the art, several improvements and modifications can be made without departing from the technical principles of the present invention, and these improvements and modifications should also be considered within the scope of protection of the present invention.

Claims

1. A device for processing a flat microfluidic reagent tray, characterized in that, The device includes a power unit, a feeding device, a processing table (301), a laser cutting device (302), a suction cup (303), a storage cylinder (304), and elastic limiting plates (305). The processing table (301) has multiple sets of positioning holes in the circumferential direction. The laser cutting device (302) is installed on a mobile device, which is used to drive the laser cutting device (302) to move and adjust in different directions. The suction cup (303) is connected to an external suction device and is installed on the power unit. The power unit is used to drive the suction cup (303) to move and to drive the rotation of the processing table (301). The storage cylinder (304) is installed on the upper part of the power unit. Multiple sets of elastic limiting plates (305) are all set at the bottom opening of the storage cylinder (304). The feeding device is set below the processing table (301) and is used to feed and transport the processed reagent tray. The power unit includes a transmission device, a base (401), a bracket (402), a support platform (403), a telescopic rod (404), a first spring (405), a gear (406), a rack (407), a lead screw (408), and a motor (409). The processing table (301) is rotatably mounted on the base (401), the bracket (402) is slidably mounted on the base (401), both ends of the support platform (403) are rotatably mounted on the bracket (402), the telescopic rod (404) is mounted on the outer wall of the support platform (403), and a suction cup (303) is mounted on the end of the telescopic rod (404). A spring (405) is installed on the telescopic rod (404), two sets of gears (406) are respectively installed on the rotating ends of the support table (403), a rack (407) is provided on the base (401) to mesh with the two sets of gears (406), a lead screw (408) is rotatably installed on the base (401), a bracket (402) is screwed on the lead screw (408), a motor (409) is installed on the base (401), the output end of the motor (409) is connected to the lead screw (408), a transmission device is provided at the bottom of the lead screw (408), and the transmission device is used to drive the rotation of the processing table (301); The transmission device includes a coupling (501), a rotating shaft (502), a sprocket (503), and a chain (504). The bottom end of the lead screw (408) is connected to the top end of the rotating shaft (502) through the coupling (501). The bottom end of the rotating shaft (502) is rotatably mounted on the base (401). The first set of sprockets (503) is mounted on the rotating shaft (502) through the first one-way bearing. The second set of sprockets (503) is mounted on the processing table (301). The two sets of sprockets (503) are driven by the chain (504). It also includes a frustum (601), a connecting arm (602), a push rod (603), a first brake pad (604), and a tension spring (605). The frustum (601) is mounted on the rotating shaft (502) via a second one-way bearing. The connecting arm (602) is rotatably mounted between the frustum (601) and the push rod (603). The push rod (603) is slidably mounted on the base (401). The end of the push rod (603) is connected to the first brake pad (604). The tension spring (605) is mounted between the base (401) and the push rod (603).

2. The device for processing a flat microfluidic reagent tray as described in claim 1, characterized in that, The feeding device includes a cylinder (701), a support (702), a lifting rod (703), an inclined block (704), and a pushing block (705). The cylinder (701) is mounted on the base (401), the support (702) is mounted on the moving end of the cylinder (701), the lifting rod (703) is rotatably mounted on the support (702), and a torsion spring is provided at the rotation point between the lifting rod (703) and the support (702). A limiting component is provided on the support (702) to limit the rotation of the lifting rod (703). The inclined block (704) is located on the outer wall of the lifting rod (703). Multiple sets of pushing blocks (705) are all located on the processing table (301), and the multiple sets of pushing blocks (705) are respectively matched with the positions of multiple sets of positioning holes.

3. The device for processing a flat microfluidic reagent tray as described in claim 1, characterized in that, It also includes a guide post (801) and a second spring (802). The guide post (801) is slidably mounted on the push rod (603). The end of the guide post (801) is connected to the first brake pad (604). The second spring (802) is mounted on the guide post (801).

4. The device for processing a flat microfluidic reagent tray as described in claim 1, characterized in that, It also includes a second brake pad (901), which is disposed on the outer wall of the bracket (402) and is interference-fitted with the rotating end of the support platform (403).

5. The device for processing a flat microfluidic reagent tray as described in claim 1, characterized in that, It also includes a conveyor trough (1001), which is located on the side of the processing table (301).

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