pH敏感的固相载体在提取、或纯化外泌体中的应用
The application of pH-sensitive solid-phase carriers has solved the problems of complex and time-consuming exosome extraction processes, achieving simple and efficient exosome extraction and purification, which is suitable for clinical applications.
CN120628715BActive Publication Date: 2026-07-17GUANGZHOU NAT LAB
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- GUANGZHOU NAT LAB
- Filing Date
- 2025-04-27
- Publication Date
- 2026-07-17
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Figure HDA0005379282080000011 
Figure HDA0005379282080000012 
Figure HDA0005379282080000021
Abstract
本发明属于生物技术领域,具体涉及pH敏感的固相载体在提取、或纯化外泌体中的应用。本发明首次将pH敏感的固相载体用于外泌体的提取或纯化,与现有的外泌体的提取或纯化方法相比,本发明具有如下优势:1)操作简便;2)时间短;3)高回收率与高纯度;4)生物稳定性;5)广泛适用性;为临床诊断提供了更为可靠的技术支持,具有巨大的临床应用价值和市场推广潜力。
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