A metal ion-crosslinked alkali-soluble Poria cocos polysaccharide hydrogel bead, its preparation method and application

Abstract

This application belongs to the field of biopolymer materials, and more specifically, relates to a metal ion crosslinked alkali-soluble Poria cocos polysaccharide hydrogel bead, its preparation method, and its application. By adding an alkali-soluble Poria cocos polysaccharide solution dropwise to a metal ion solution, various metal ion crosslinked Poria cocos polysaccharide hydrogel beads can be obtained. The metal ion crosslinked Poria cocos polysaccharide hydrogel beads of this invention exhibit excellent coagulation properties, enabling red blood cells to aggregate on the material surface, avoiding excessive blood dispersion that hinders coagulation. The preparation of the hydrogel beads of this invention does not require the addition of additional crosslinking agents, avoiding the toxicity associated with chemical crosslinking agents, and possesses good biocompatibility and excellent antibacterial properties. This Poria cocos polysaccharide hydrogel bead has promising application prospects as a novel polysaccharide medical material.

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