An automatic elution nasopharyngeal swab

Abstract

The application provides an automatic elution nasopharyngeal swab and belongs to the technical field of medical devices. The automatic elution nasopharyngeal swab comprises a swab rod and an elution device. One end of the swab rod is provided with a sampling head. The elution device comprises a shell. An elution cavity is arranged in the shell. An elution liquid is arranged in the elution cavity. An elution mechanism is arranged in the middle of the elution cavity. Two ends of the shell are both provided with an opening hole communicating with the elution cavity. A sealing mechanism is arranged on one side of the opening hole. A collection mechanism is arranged on one end of the shell. A liquid taking mechanism is arranged on the side wall of the other end of the shell. The swab rod can pass through the whole shell of the elution device through the opening hole and enter the nasopharynx of a sampled person to collect samples. In the process of pulling out the swab rod, the elution mechanism extrudes the sampling head to fully mix and elute the samples and the elution liquid, directly completing sampling and elution. The operation process is simple, and the risk of sample pollution is effectively avoided.

Description

Technical Field

[0001] This invention relates to the field of medical device technology, and more specifically, to an automatic nasopharyngeal swab. Background Technology

[0002] In the field of medical diagnostics, rapid antigen testing for respiratory viruses plays a crucial role. From a diagnostic perspective, it provides key evidence for disease diagnosis, helping doctors quickly develop precise treatment plans. In patient management, it facilitates timely patient classification and targeted care, improving treatment outcomes. For guiding clinical medication, it enables doctors to rationally select drugs based on test results, avoiding indiscriminate use. In controlling transmission routes, rapid testing can promptly identify sources of infection, allowing for effective isolation and other control measures to cut off transmission chains. From a public health perspective, it can monitor and provide early warning of the epidemic trends of respiratory infectious diseases, providing data support for the formulation of prevention and control strategies.

[0003] With continuous technological iteration and ongoing improvements in reagent kits, rapid antigen testing has made significant progress in terms of ease of operation. Today, this test does not require a dedicated laboratory environment or professional testing personnel. It can be performed by doctors or nurses in outpatient clinics of medical institutions, or patients can conduct the test at home. This transformation has greatly improved the efficiency of medical resource utilization, especially during periods of high incidence of respiratory infectious diseases, effectively alleviating the problem of insufficient testing capacity in laboratory departments and providing strong support for the efficient operation of the medical system.

[0004] However, viral sample elution, as an indispensable key step in antigen detection, still faces many problems that urgently need to be solved. Most existing nasopharyngeal swab sampling and sample processing procedures rely on manual operation. After the swab is collected, it must be placed into a sampling tube containing preservation solution immediately and the swab must be rotated several times to ensure that it is fully mixed with the processing solution. Then, the swab head must be squeezed through the outer wall of the sampling tube to ensure that the viral antigens in the sample can be fully released into the preservation solution. However, this traditional method has a series of drawbacks.

[0005] Existing virus sampling and sample elution processes involve multiple steps and are complex, which undoubtedly places high demands on the skill level of operators. Slight improper operation may affect the accuracy of test results. After nasopharyngeal swab sampling, the sample needs to be placed for a waiting period, and the process of manually opening the sample elution solution can easily introduce external contaminants, increasing the risk of sample contamination. The requirements for the operating environment and the standardized operation of personnel are extremely stringent. In the virus sample elution stage, due to differences in operating techniques or inappropriate selection of elution solution, the virus often cannot be completely released from the sample, thus affecting the sensitivity and reliability of the test results.

[0006] To address the shortcomings of existing technologies, many have explored new approaches. For example, the invention patent with authorization announcement number CN114305515B proposes a pharyngeal swab sampling device and system. Through the design of the pharyngeal swab storage tube and the subsequent automatic clamping function, it provides some ideas for the intelligent and automated pharyngeal swab sampling process. However, the pharyngeal swab sampling and post-sampling elution processes in this patent have not been effectively optimized and simplified, and the risk of sample contamination remains difficult to avoid during operation, making the overall solution incomplete. The invention patent with authorization announcement number CN111673743B designs a pharyngeal swab collection robot, enabling manual operation via a control terminal to drive the robotic arm to complete pharyngeal specimen collection. However, the robot's research, development, manufacturing, and maintenance costs are high, limiting its application to institutional settings and hindering its widespread adoption by the public, resulting in significant shortcomings in terms of convenience. The utility model patent with authorization announcement number CN221932006U provides a pharyngeal swab collector. It mainly improves the sampling efficiency by improving the shape design of the sampling device and increasing the sampling area covered by the deformable part. It also reduces the discomfort caused to the sampled object to a certain extent. However, this patent does not solve the core problems of contamination and infection in the nasopharyngeal swab sampling and sample processing process, as well as the cumbersome washing operation. Summary of the Invention

[0007] The technical problem to be solved by the present invention is to provide an automated nasopharyngeal swab to solve the problem that the existing nasopharyngeal swab sampling and sample processing procedures mostly rely on manual operation, the operation steps are cumbersome, the requirements for the operation environment and the standardized operation of personnel are extremely strict, and the samples are easily contaminated.

[0008] To solve the above problems, the present invention adopts the following technical solution:

[0009] An automatic nasopharyngeal swab includes a swab rod and an elution device. A sampling head is provided at one end of the swab rod. The elution device includes a housing with an elution chamber inside. The elution chamber contains an eluent. An elution mechanism is provided in the middle of the elution chamber. Openings communicating with the elution chamber are provided at both ends of the housing. A sealing mechanism is provided on one side of each opening. A collection mechanism is provided at one end of the housing, and a liquid collection mechanism is provided on the side wall of the other end of the housing.

[0010] An observation window is provided on the side wall of the housing near the liquid extraction mechanism, and a transparent elastic compression plate is installed on the inner side of the observation window.

[0011] The elution mechanism includes an installation ring sleeve, which is fixedly installed inside the elution chamber. A base plate is disposed inside the installation ring sleeve, and the base plate is arranged in a ring shape. An elastic extrusion plate is fixedly connected to the inner side of the base plate.

[0012] The liquid collection mechanism includes a draining hopper, which is disposed on the side wall of the housing and communicates with the elution chamber. A sealing plug is installed at the bottom of the draining hopper, and an anti-loss rope is fixedly connected to the outside of the sealing plug. The end of the anti-loss rope away from the sealing plug is fixedly connected to the housing.

[0013] The sealing plug has a sealing head at its top, and a guide cone is provided at the top of the sealing head. The sealing head is in the shape of an inverted cone, and the guide cone is in the shape of a cone.

[0014] The sealing mechanism includes a sealing plate disposed on the side of the opening away from the collecting mechanism, and a filling plug adapted to the opening is provided on the sealing plate; the sealing mechanism also includes a hinge seat disposed next to the sealing plate, the hinge seat being fixedly connected to the housing, a support rod being mounted on the hinge seat, a rotating shaft being sleeved on the support rod, the rotating shaft being rotatably connected to the support rod, and the rotating shaft being fixedly connected to the sealing plate.

[0015] The hinge seat has an inner mounting groove, a torsion spring is installed in the mounting groove, the torsion spring is sleeved on the outside of the support rod, one end of the torsion spring is fixed in the mounting groove, and the other end is fixedly connected to the rotating shaft.

[0016] The collection mechanism includes a collection shell, which is fixedly connected to the housing. Guide rails are provided on both sides of the collection shell, and a push plate is slidably connected inside the guide rails. A pressing plate is provided on the outer side of the push plate, and an arc-shaped cutting blade is provided on the inner side of the push plate. The arc-shaped cutting blade is located inside the collection shell. A telescopic spring is also provided on the inner side of the push plate. One end of the telescopic spring is connected to the push plate, and the other end is connected to the inner wall of the collection shell.

[0017] The collecting shell has a perforation at one end, and a sealing plate is provided on the outside of the perforation. A magnetic ring is provided on the inside of the sealing plate and the outside of the collecting shell. The sealing plate can be attracted to the outside of the perforation by the magnetic ring.

[0018] Compared with the prior art, the technical solution provided by this invention has at least the following beneficial effects:

[0019] In the above scheme, by setting an opening, the swab rod can pass through the entire shell of the elution device and enter the nasopharynx of the sampled person to collect samples. During the process of pulling out the swab rod, the elution mechanism will squeeze the sampling head to fully mix and elute the sample with the elution solution, directly completing the sampling and elution process. The operation process is simple and effectively avoids the risk of sample contamination. Attached Figure Description

[0020] The accompanying drawings, which are incorporated herein and form part of the specification, illustrate embodiments of the invention and, together with the specification, further serve to explain the principles of the invention and enable those skilled in the art to practice and use the invention.

[0021] Figure 1 This is a three-dimensional structural diagram of the present invention;

[0022] Figure 2 This is a top view of the structure of the present invention;

[0023] Figure 3 This is a bottom-view structural diagram of the present invention;

[0024] Figure 4 This is a schematic diagram of the internal structure of the housing of the present invention;

[0025] Figure 5 This is a schematic diagram of the internal structure of the collection mechanism of the present invention;

[0026] Figure 6 This is a schematic diagram of the sealing mechanism of the present invention in a disassembled state;

[0027] Figure 7 This is a schematic diagram of the push plate and telescopic spring structure of the present invention;

[0028] Figure 8 for Figure 4 Schematic diagram of the structure at point A;

[0029] Figure 9 This is a schematic diagram of the sealing plug structure of the present invention.

[0030] [Figure Labels]

[0031] 1. Swab stick;

[0032] 2. Washing and extracting device; 21. Shell; 22. Opening;

[0033] 23. Collection mechanism; 231. Collection shell; 232. Guide rail; 233. Sealing plate; 234. Push plate; 235. Arc-shaped shearing blade; 236. Telescopic spring; 237. Perforation; 238. Pressing plate;

[0034] 24. Washing chamber;

[0035] 25. Liquid dispensing mechanism; 251. Liquid discharge hopper; 252. Sealing plug; 253. Anti-loss rope; 254. Sealing plug; 255. Guide cone block;

[0036] 26. Sealing mechanism; 261. Hinge seat; 262. Mounting groove; 263. Torsion spring; 264. Rotating shaft; 265. Sealing plate; 266. Filler plug;

[0037] 27. Washing and elution mechanism; 271. Mounting ring; 272. Substrate; 273. Elastic extrusion plate;

[0038] 28. Anti-slip raised ring; 29. ​​Observation window;

[0039] 3. Sampling head;

[0040] 4. Transparent elastic extruded plate.

[0041] As shown in the figure, specific structures and devices are marked in the figure to clearly illustrate the structure of the embodiments of the present invention. However, this is only for illustrative purposes and is not intended to limit the present invention to this specific structure, device and environment. Those skilled in the art can adjust or modify these devices and environments according to specific needs. Detailed Implementation

[0042] The present invention will now be described in detail with reference to the accompanying drawings and specific embodiments. It should also be noted that, to make the embodiments more comprehensive, the following embodiments are the best and preferred embodiments, and those skilled in the art can use other alternative methods to implement some well-known technologies; moreover, the accompanying drawings are only for more specific description of the embodiments and are not intended to specifically limit the present invention.

[0043] It should be noted that the use of terms such as "an embodiment," "an embodiment," "an exemplary embodiment," and "some embodiments" in the specification indicates that the described embodiment may include a specific feature, structure, or characteristic, but not every embodiment necessarily includes that specific feature, structure, or characteristic. Furthermore, when a specific feature, structure, or characteristic is described in connection with an embodiment, implementing such a feature, structure, or characteristic in conjunction with other embodiments (whether explicitly described or not) should be within the knowledge of those skilled in the art.

[0044] Generally, terms can be understood at least partly from their use in context. For example, depending at least partly on the context, the term "one or more" as used herein can be used to describe any feature, structure, or characteristic in a singular sense, or a combination of features, structures, or characteristics in a plural sense. Additionally, the term "based on" can be understood not necessarily to convey an exclusive set of factors, but rather, alternatively, depending at least partly on the context, to allow for the presence of other factors that are not necessarily explicitly described.

[0045] It is understood that the meanings of “on”, “above”, and “above” in this invention should be interpreted in the broadest manner, such that “on” means not only “directly on” something, but also includes the meaning of being “on” something with an intervening feature or layer, and that “above” or “above” means not only “on” something, but also includes the meaning of being “on” something without an intervening feature or layer.

[0046] Furthermore, spatially related terms such as “below,” “under,” “lower,” “above,” and “upper” are used herein for convenience to describe the relationship of one element or feature to one or more other elements or features, as illustrated in the accompanying drawings. Spatially related terms are intended to cover different orientations in the use or operation of the device other than those depicted in the accompanying drawings. The device may be oriented in other ways, and the spatially related descriptive terms used herein can be interpreted similarly.

[0047] like Figures 1 to 9 As shown, this embodiment of the invention provides an automatic nasopharyngeal swab, including a swab rod 1 and an elution device 2. One end of the swab rod 1 is provided with a sampling head 3. The elution device 2 includes a housing 21, and the inside of the housing 21 is provided with an elution chamber 24 containing an elution solution. An elution mechanism 27 is provided in the middle of the elution chamber 24. Both ends of the housing 21 are provided with openings 22 that communicate with the elution chamber 24. A sealing mechanism 26 is provided on one side of the opening 22. A collection mechanism 23 is provided at one end of the housing 21, and a liquid collection mechanism 25 is provided on the side wall of the other end of the housing 21.

[0048] like Figures 1 to 5 As shown, the outer surface of the housing 21 is evenly distributed with anti-slip protrusions 28. An observation window 29 is provided on the side wall of the housing 21 near the liquid collection mechanism 25. There are two observation windows 29, symmetrically arranged. A transparent elastic squeezing plate 4, made of transparent silicone rubber, is installed inside the observation window 29. The anti-slip protrusions 28 effectively increase the friction when the operator holds the device, preventing it from slipping and falling during operation, ensuring operational stability. The observation windows 29 allow the operator to directly observe the conditions inside the elution chamber 24, such as the remaining amount of eluent and the mixing state of the sample and eluent. The transparent elastic squeezing plate 4 not only has good transparency for easy observation but also elasticity. When it is necessary to squeeze out the eluent, squeezing the transparent elastic squeezing plate 4 applies pressure to the eluent in the elution chamber 24, causing the eluent to be discharged from the liquid collection mechanism 25.

[0049] The elution mechanism 27 includes a mounting ring 271, which is fixedly installed inside the elution chamber 24. A base plate 272 is disposed inside the mounting ring 271, and the base plates 272 are arranged in a ring at equal intervals. An elastic extrusion plate 273 is fixedly connected to the inner side of the base plate 272. When the swab rod 1, carrying the sampling head 3, is inserted into the elution chamber 24, it extrudes the elastic extrusion plate 273, causing it to deform. During the extraction of the sampling head 3, the elastic extrusion plate 273 rebounds, and the operator can rotate the swab rod 1. At this time, the elastic extrusion plate 273 acts like an elastic bristle structure, fully extruding the sampling head 3, causing the human mucus tissue collected on the sampling head 3 to mix evenly with the elution solution, achieving sufficient contact and mixing of the sample and the processing solution, thereby ensuring the high efficiency and uniformity of sample elution.

[0050] like Figure 1 , Figure 8 and Figure 9 As shown, the liquid collection mechanism 25 includes a drain hopper 251, which is disposed on the side wall of the housing 21 and communicates with the elution chamber 24. A sealing plug 252 is installed at the bottom of the drain hopper 251, and an anti-loss rope 253 is fixedly connected to the outside of the sealing plug 252. The end of the anti-loss rope 253 away from the sealing plug 252 is fixedly connected to the housing 21. A sealing plug 254 is provided at the top of the sealing plug 252, and a guide cone 255 is provided at the top of the sealing plug 254. The sealing plug 254 is inverted cone shape, and the guide cone 255 is cone shape. Both the sealing plug 254 and the guide cone 255 are made of elastic sealing silicone material.

[0051] When elution is complete and liquid needs to be collected, the operator pulls the anti-loss rope 253, causing the sealing plug 252 to be pulled out from the bottom of the drain hopper 251, opening the drain hopper 251. Then, the transparent elastic pressure plate 4 inside the observation window 29 is squeezed to apply pressure to the eluent in the elution chamber 24, causing the eluent to flow out through the drain hopper 251 for subsequent testing. After liquid collection, the sealing plug 254 is moved toward the drain hopper 251. Due to its conical structure, the guide cone 255 guides the sealing plug 254 as it approaches the drain hopper 251, making it easy and accurate to insert the sealing plug 254 into the drain hopper 251. Since the sealing plug 254 is an inverted cone and both the sealing plug and the guide cone 255 are made of elastic sealing silicone, they fit tightly against the inner wall of the drain hopper 251 after insertion, achieving a good sealing effect and preventing eluent leakage. The anti-loss rope 253 prevents the sealing plug 252 from being lost during operation, making it easy to find and operate it quickly next time.

[0052] like Figure 4 , Figure 6 and Figure 8As shown, the sealing mechanism 26 includes a sealing plate 265, which is disposed on the side of the opening 22 away from the collecting mechanism 23. The sealing plate 265 is provided with a filling plug 266 for blocking the opening 22. The filling plug 266 is adapted to the opening 22 and is specifically hemispherical. The sealing mechanism 26 also includes a hinge seat 261 disposed next to the sealing plate 265. The hinge seat 261 is fixedly connected to the housing 21. A support rod is installed on the hinge seat 261. A rotating shaft 264 is sleeved on the support rod. The rotating shaft 264 is rotatably connected to the support rod and is fixedly connected to the sealing plate 265. An installation groove 262 is opened on the inner side of the hinge seat 261. A torsion spring 263 is disposed in the installation groove 262. The torsion spring 263 is sleeved on the outer side of the support rod. One end of the torsion spring 263 is fixed in the installation groove 262, and the other end is fixedly connected to the rotating shaft 264.

[0053] When the swab rod 1 with the sampling head 3 is inserted into the housing 21, the sampling head 3 will first contact the sealing plate 265 and the filling plug 266 near the end of the collection mechanism 23. The sealing plate 265 is compressed, which drives the rotating shaft 264 connected to it to rotate in the hinge seat 261. At this time, the rotating shaft 264 compresses the torsion spring 263 in the mounting groove 262, causing it to store elastic potential energy. When the sealing plate 265 is pushed open and the filling plug 266 leaves the corresponding opening 22, the sampling head 3 can pass through the opening 22 and enter the elution chamber 24. As the sampling head 3 continues to... The sampling head 3 penetrates the elution chamber 24, pushes aside the sealing plate 265 at the other end, and thus passes through the entire housing 21 to enter the nasopharynx of the sampled person for sample collection. After sampling, the swab rod 1 is pulled out of the housing 21. Since the sealing plate 265 loses the squeezing force of the sampling head 3, the torsion spring 263, which is in a compressed state, will release its elastic potential energy, pushing the rotating shaft 264 to rotate in the opposite direction. This causes the sealing plate 265 to cover the opening 22 again, and the filling plug 266 also re-blocks the opening 22, achieving automatic sealing of the opening 22. During the insertion of the swab rod 1 into the elution chamber 24, since the swab rod 1 is located inside the opening 22 and the eluent has a certain viscosity, the eluent will not overflow from the opening 22. During the process of the swab rod 1 entering and exiting the housing 21, the sealing mechanism 26 can automatically reseal, effectively avoiding the leakage of eluent and collected bacteria, minimizing the risk of virus and bacteria leakage, and effectively preventing external pollutants from entering, ensuring the stability and safety of the internal environment of the device.

[0054] like Figures 1 to 5 and Figure 7As shown, the collection mechanism 23 includes a collection shell 231, which is fixedly connected to the shell 21. Guide rails 232 are provided on both sides of the collection shell 231. Push plates 234 are slidably connected inside the guide rails 232. Pressing plates 238 are provided on the outer side of the push plates 234. Arc-shaped cutting blades 235 are provided on the inner side of the push plates 234, located inside the collection shell 231. Two telescopic springs 236 are fixedly connected to the inner side of each push plate 234, symmetrically arranged on both sides of the corresponding arc-shaped cutting blades 235. One end of each telescopic spring 236 is connected to the push plate 234, and the other end is connected to the inner wall of the collection shell 231. During sampling, the telescopic springs 236 are in a naturally extended state, and the arc-shaped cutting blades 235 are away from the sampling head 3 path, thus not affecting the sampling operation. The end of the collecting shell 231 is provided with a perforation 237, and a sealing plate 233 is provided on the outside of the perforation 237. The sealing plate 233 is rotatably connected to the collecting shell 231, and a magnetic ring is provided on the inner side of the sealing plate 233 and the outer side of the collecting shell 231. The sealing plate 233 can be attracted to the outside of the perforation 237 through the magnetic ring.

[0055] After sample elution is complete, if the sampling head 3 needs to be collected, the operator can squeeze the pressing plate 238. The pressing plate 238 drives the push plate 234 to slide inward along the guide rail 232, and the arc-shaped cutting blade 235 also moves accordingly. When the arc-shaped cutting blade 235 moves to the sampling head 3, the swab rod 1 is pulled forcefully to cut off the sampling head 3. The cut sampling head 3 falls into the collection shell 231. After releasing the pressing plate 238, the telescopic spring 236 will push the push plate 234 outward to return to the initial state. After collection is completed, the sealing plate 233 is rotated to seal the perforation 237 to prevent the sampling head 3 from leaking. Subsequently, the sealing plate 233 can be opened to discharge the sampling head 3 from the collection shell 231 for centralized processing.

[0056] The workflow of the technical solution provided by this invention is as follows:

[0057] During use, the operator inserts the swab rod 1 into the perforation 237. The sampling head 3 at the front end of the swab rod 1 applies pressure to the sealing plate 265 and the filling plug 266 near the collection mechanism 23, causing the first sealing plate 265 to be opened smoothly. As the sampling head 3 continues to go deeper, it pushes the sealing plate 265 at the other end, smoothly passing through the elution chamber 24 and the entire housing 21, and is inserted into the nasopharynx of the sampled person to collect samples. During the process of removing the sampling head 3 after sampling, the elastic squeezing plate 273 applies pressure to the sampling head 3. During this process, by rotating the swab rod 1, the human mucus tissue collected on the sampling head 3 can be evenly mixed with the elution fluid inside the elution chamber 24.

[0058] When the sample and eluent are mixed and liquid needs to be collected, pull the anti-loss rope 253 to pull the sealing plug 252 out from the inside of the drain hopper 251. Then squeeze the transparent elastic squeezing plate 4 to squeeze the eluent inside the shell 21 out from the drain hopper 251 to achieve rapid liquid collection. After the liquid collection is completed, under the action of the guide cone block 255, the sealing plug 254 can be easily and accurately inserted into the drain hopper 251.

[0059] When it is necessary to collect and process the sampling head 3, squeeze the pressing plate 238 to drive the push plate 234 and the arc-shaped cutting blade 235 to move inward until the arc-shaped cutting blade 235 is stably attached to the sampling head 3. At this time, forcefully pull the swab rod 1 to cut off the sampling head 3, so that the sampling head 3 is collected inside the collection shell 231.

[0060] In the above-described solution, the automatic nasopharyngeal swab offers high convenience, safety, and sealing performance. By providing an opening, the swab can pass through the entire housing of the elution device and enter the nasopharynx of the sampled individual for sample collection. During the swab removal process, the elution mechanism squeezes the sampling head, ensuring thorough mixing and elution of the sample with the eluent, directly completing the sampling and elution process. The operation is simple and effectively avoids the risk of sample contamination. A collection mechanism collects the sampling head, preventing potential viral or bacterial contamination after direct extraction. The sealing mechanism automatically seals after the swab is removed, preventing leakage of the eluent and bacteria. A liquid collection mechanism enables rapid liquid collection.

[0061] This invention encompasses any substitutions, modifications, equivalent methods, and solutions made within the spirit and scope of this invention. To provide the public with a thorough understanding of this invention, specific details are described in detail in the preferred embodiments, while those skilled in the art will fully understand the invention even without these details. Furthermore, to avoid unnecessary misunderstanding of the essence of this invention, well-known methods, processes, procedures, components, and circuits are not described in detail.

[0062] The above description is only a preferred embodiment of the present invention. It should be noted that for those skilled in the art, several improvements and modifications can be made without departing from the principle of the present invention, and these improvements and modifications should also be considered within the scope of protection of the present invention.

Claims

1. An automatically eluting nasopharyngeal swab, comprising a swab rod and an elution device, wherein a sampling head is provided at one end of the swab rod, characterized in that, The elution device includes a housing, an elution chamber inside the housing, an eluent inside the elution chamber, an elution mechanism in the middle of the elution chamber, openings at both ends of the housing that communicate with the elution chamber, a sealing mechanism on one side of each opening, a collection mechanism at one end of the housing, and a liquid collection mechanism on the side wall of the other end of the housing. The liquid collection mechanism includes a liquid discharge hopper, which is disposed on the side wall of the housing and communicates with the elution chamber. A sealing plug is installed at the bottom of the liquid discharge hopper. The sealing mechanism includes a sealing plate disposed on the side of the opening away from the collecting mechanism, and a filling plug adapted to the opening is provided on the sealing plate; the sealing mechanism also includes a hinge seat disposed next to the sealing plate, the hinge seat being fixedly connected to the housing, a support rod being mounted on the hinge seat, a rotating shaft being sleeved on the support rod, the rotating shaft being rotatably connected to the support rod, and the rotating shaft being fixedly connected to the sealing plate; The inner side of the hinge seat is provided with a mounting groove, and a torsion spring is provided in the mounting groove. The torsion spring is sleeved on the outside of the support rod, one end of the torsion spring is fixed in the mounting groove, and the other end is fixedly connected to the rotating shaft. The collecting mechanism includes a collecting shell, which is fixedly connected to the housing. Guide rails are provided on both sides of the collecting shell. A push plate is slidably connected inside the guide rails. A pressing plate is provided on the outer side of the push plate. An arc-shaped shearing blade is provided on the inner side of the push plate. The elution mechanism includes an installation ring sleeve, which is fixedly installed inside the elution chamber. A base plate is provided inside the installation ring sleeve, and the base plate is arranged in a ring. An elastic extrusion plate is fixedly connected to the inner side of the base plate. The elastic extrusion plate is like an elastic bristle structure, which can fully extrude the sampling head and promote the uniform mixing of the human mucus tissue collected on the sampling head with the elution solution. The end of the collecting shell has a perforation, and a sealing plate is provided on the outside of the perforation. The sealing plate is rotatably connected to the collecting shell, and a magnetic ring is provided on the inner side of the sealing plate and the outer side of the collecting shell. The sealing plate can be attracted to the outside of the perforation by the magnetic ring.

2. The automatically eluting nasopharyngeal swab according to claim 1, characterized in that, An observation window is provided on the side wall of the housing near the liquid extraction mechanism, and a transparent elastic compression plate is installed on the inner side of the observation window.

3. The automatically eluting nasopharyngeal swab according to claim 1, characterized in that, An anti-loss rope is fixedly connected to the outside of the sealing plug, and the end of the anti-loss rope away from the sealing plug is fixedly connected to the shell.

4. The automatically eluting nasopharyngeal swab according to claim 3, characterized in that, The sealing plug has a sealing head at its top, and a guide cone is provided at the top of the sealing head. The sealing plug is in the shape of an inverted cone, and the guide cone is in the shape of a cone.

5. The automatically eluting nasopharyngeal swab according to claim 1, characterized in that, The arc-shaped cutting blade is located inside the collection shell. A telescopic spring is also provided on the inner side of the push plate. One end of the telescopic spring is connected to the push plate, and the other end is connected to the inner wall of the collection shell.

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