Portable stable type urine protein qualitative detection kit

Abstract

The application provides a portable stable urine protein qualitative detection kit, relates to the technical field of urine protein qualitative detection, and comprises a kit body; a uniform tank is fixedly installed at the inner front end position of the kit body, a conveying pipe is penetrated into the inner middle position of the uniform tank, a ring-shaped array of through holes is formed in the position surface of the conveying pipe in the uniform tank, and a limiting sleeve is fixedly connected to the top position of the conveying pipe. The kit is internally provided with the uniform tank, a motor drives the bevel gear and the ring gear, drives the vertical plate at the bottom of the ring gear to rotate in the uniform tank, can sufficiently stir and uniformly the liquid sample, can make the protein in the sample more uniformly distributed, makes the detection result more accurately reflect the actual content of the protein in the urine, and improves the reliability of detection. The kit lacks an effective sample uniform processing mechanism, if the urine sample is not sufficiently uniform before detection, the protein concentration of the detection position is inconsistent, and the detection result is deviated.

Description

Technical Field

[0001] This invention relates to the field of qualitative detection technology for urine protein, and particularly to a portable, stable qualitative detection kit for urine protein. Background Technology

[0002] Qualitative testing of urine protein is an important means of clinical diagnosis of kidney disease, diabetes and other conditions. The accuracy of the test results and the convenience of the testing process are of great significance to medical diagnosis. Currently, portable testing methods use urine protein qualitative test kits for detection.

[0003] Application number CN202221091422.0 discloses a rapid detection kit for qualitative analysis of urine protein. It features a simple design, reasonable structure, fast detection speed, high sensitivity and specificity, ease of use, and low manufacturing cost, making it suitable for large-scale application. It is especially suitable for the rapid qualitative detection of prostatic small effusive protein (PSEP) in urine to screen for chronic prostatitis.

[0004] Based on the above patent search and understanding of the application of existing urine protein qualitative detection kits: 1. Traditional reagent kits lack a reliable sealing structure during sample injection, which can easily lead to impurities entering and contaminating the sample, affecting the accuracy of the test.

[0005] 2. The kit lacks an effective sample homogenization mechanism. If the urine sample is not sufficiently homogenized before testing, the protein concentration at the testing site will be inconsistent, resulting in biased test results that cannot accurately reflect the true situation of protein in the urine.

[0006] Therefore, in view of this, we have studied and improved the existing structure and its shortcomings to provide a portable and stable qualitative test kit for urine protein, in order to achieve a more practical purpose. Summary of the Invention

[0007] To address the aforementioned technical problems, this invention provides a portable and stable urine protein qualitative detection kit. This kit solves the problems of existing traditional kits lacking a reliable sealing structure during sample injection, which easily leads to impurities entering and contaminating the sample, affecting detection accuracy; and the lack of an effective sample homogenization mechanism, which results in inconsistent protein concentrations at the detection site if the urine sample is not sufficiently homogenized before testing, leading to deviations in the test results.

[0008] This invention provides a portable and stable qualitative urine protein detection kit, specifically comprising: a kit body; a homogenizing tank fixedly installed at the front end of the kit body, a delivery tube passing through the middle of the homogenizing tank, the delivery tube having an annular array of through holes on its surface inside the homogenizing tank, a limiting sleeve fixedly connected to the top of the delivery tube, a conical groove provided at the upper part of the inner side of the limiting sleeve, and a hollow limiting frame fixedly connected to the middle of the top of the limiting sleeve, a Y-shaped frame A fixedly installed at the lower part of the inner side of the limiting sleeve, an umbrella-shaped plug A slidably connected to the upper part of the inner side of the Y-shaped frame A, and an inclined surface of the umbrella-shaped plug A having... A sealing ring is provided, and the umbrella-shaped inclined surface of the umbrella-shaped plug A is fitted with the conical groove of the limiting sleeve. A spring A is sleeved on the lower middle position of the umbrella-shaped plug A. The top position of the spring A is fitted with the lower umbrella-shaped position of the umbrella-shaped plug A. The bottom position of the spring A is fitted with the top position of the Y-shaped frame A. A transverse groove is provided at the middle position of the top of the umbrella-shaped plug A. A transmission frame is symmetrically slidably connected to the left and right sides of the top of the limiting frame. A spring C is sleeved on the outer end of the sliding position of each transmission frame and the limiting frame. Two reset pieces are rotatably connected to the left and right sides of the top of the limiting frame. A support foot is provided on each side of the transmission frame, and the support foot of each transmission frame is inserted into a reset piece.

[0009] Furthermore, a counterweight is fixedly installed at the bottom rear of the reagent kit, and the bottom of the counterweight is fixedly connected to the top rear of the base plate. The base plate is located directly below the reagent kit, and a partition is provided in the middle of the inside of the reagent kit.

[0010] Furthermore, a battery compartment is provided inside the front end of the reagent kit, a motor is provided at the upper part of the battery compartment, and a placement slot is provided at the rear top of the reagent kit, where a test reagent is placed, and the test reagent is located behind the partition.

[0011] Furthermore, an annular frame is fixedly installed at the upper part of the interior of the uniform tank, and an annular gear is rotatably connected to the interior of the annular frame. The conveying pipe passes through the middle of the annular frame and the annular gear, and six vertical plates are provided at the bottom of the annular gear.

[0012] Furthermore, a bevel gear is rotatably connected to the front end of the inner side of the ring frame. The bevel gear meshes with the front end of the top of the ring gear, and the front end of the bevel gear is fixedly connected to the motor shaft.

[0013] Furthermore, an output sleeve is provided at the bottom of the conveying pipe, a conical groove is provided at the lower part of the inside of the output sleeve, a Y-shaped frame B is fixedly installed at the upper part of the inside of the output sleeve, an umbrella-shaped plug B is slidably connected at the lower part of the inside of the Y-shaped frame B, and a sealing ring is provided on the inclined surface of the umbrella-shaped part of the umbrella-shaped plug B.

[0014] Furthermore, the umbrella-shaped inclined surface of the umbrella-shaped plug B is fitted to the conical groove of the output sleeve, a spring B is sleeved on the upper middle position of the umbrella-shaped plug B, the bottom position of the spring B is fitted to the upper umbrella position of the umbrella-shaped plug B, and the top position of the spring B is fitted to the bottom position of the Y-shaped frame B.

[0015] Compared with the prior art, the present invention has the following beneficial effects: 1. The kit contains a homogenizing container. A motor drives a bevel gear and a ring gear, which in turn rotates a vertical plate at the bottom of the ring gear inside the homogenizing container. This ensures that the liquid sample is thoroughly mixed and homogenized, resulting in a more uniform distribution of proteins in the sample. This allows the test results to more accurately reflect the actual protein content in the urine, thus improving the reliability of the test.

[0016] 2. The transmission frame at the top of the limiting frame cooperates with the reset component through spring C. After the sample injection is completed, the force of the reset component can push the needle tube that has not been removed in time upward, avoiding the failure of the seal due to the needle tube being left behind. At the same time, it reduces the number of operation steps and improves the detection efficiency.

[0017] 3. When the test reagent is placed at the bottom front of the reagent kit, its rear end fits against the front end of the counterweight, ensuring that the detection position is accurately aligned with the output sleeve. Moving the test reagent upward will push the umbrella-shaped plug B to open the sampling operation. The operation is simple and intuitive. After sampling, the spring B quickly resets, reducing sample exposure time and lowering the risk of contamination.

[0018] 4. The reagent kit's interior is divided by partitions, with the battery compartment and motor located at the front and the test reagents at the rear. The structure is compact and the functional areas are clearly defined. The overall design balances portability with automated testing capabilities, completing the entire process of sample injection, homogenization, sampling, and colorimetric analysis without the need for additional equipment. It is suitable for various scenarios, including medical settings and home testing. Attached Figure Description

[0019] To more clearly illustrate the technical solutions of the embodiments of the present invention, the accompanying drawings of the embodiments will be briefly described below.

[0020] In the attached diagram: Figure 1 A side view of the portable, stable urine protein qualitative detection kit according to an embodiment of the present invention is shown. Figure 2 A schematic diagram of the left-side half-section structure of the portable, stable urine protein qualitative detection kit according to an embodiment of the present invention is shown. Figure 3 A schematic half-sectional side view of the portable, stable urine protein qualitative detection kit according to an embodiment of the present invention is shown. Figure 4 A schematic diagram of a half-section side view of the reagent kit body according to an embodiment of the present invention is shown; Figure 5 A semi-sectional front view of the uniform tank, output sleeve, and limiting frame according to an embodiment of the present invention is shown; Figure 6 A schematic diagram of the uniform tank, output sleeve, and limiting frame in half section (left view) according to an embodiment of the present invention is shown. Figure 7 A schematic half-section side view of the uniform tank, output sleeve, and limiting frame according to an embodiment of the present invention is shown; Figure 8 An embodiment of the present invention is shown. Figure 7 A magnified schematic diagram of the structure at point A in the middle.

[0021] List of reference numerals 1. Reagent kit; 101. Counterweight; 102. Base plate; 103. Divider; 104. Battery box; 105. Motor; 2. Uniform tank; 201. Delivery tube; 202. Ring frame; 203. Ring gear; 204. Limiting sleeve; 205. Y-shaped frame A; 206. Umbrella-shaped plug A; 207. Spring A; 208. Bevel gear; 3. Output sleeve; 301. Y-shaped frame B; 302. Umbrella-shaped plug B; 303. Spring B; 4. Limiting frame; 401. Transmission frame; 402. Spring C; 403. Support leg; 404. Reset component; 5. Test reagent kit. Detailed Implementation

[0022] The technical solutions of the embodiments of this disclosure will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of this disclosure, and not all embodiments. Based on the embodiments of this disclosure, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of this disclosure.

[0023] Unless otherwise defined, all terms (including technical and scientific terms) used in the embodiments of this disclosure shall have the same meaning as commonly understood by one of ordinary skill in the art to which this disclosure pertains. It should also be understood that terms such as those defined in a common dictionary shall be interpreted as having a meaning consistent with their meaning in the context of the relevant art, and not as being interpreted in an idealized or highly formalized sense, unless expressly defined in the embodiments of this disclosure.

[0024] The terms "first," "second," and similar words used in the embodiments of this disclosure do not indicate any order, quantity, or importance, but are merely used to distinguish different components. Similarly, the terms "a," "one," or "the" do not indicate a quantity limitation, but rather indicate the presence of at least one. Likewise, the terms "comprising" or "including" mean that the element or object preceding the word encompasses the elements or objects listed after the word and their equivalents, without excluding other elements or objects. In the following description, spatial and directional terms such as "upper," "lower," "front," "rear," "top," "bottom," "vertical," and "horizontal" may be used to describe embodiments of this disclosure; however, it should be understood that these terms are only for the convenience of describing the embodiments shown in the figures and do not require the actual device to be constructed or operated in a specific orientation. In the following description, the use of terms such as "connected," "joined," "fixed," and "attached" can refer to a direct connection between two elements or structures without other elements or structures, or to an indirect connection between two elements or structures via an intermediate element or structure, unless otherwise expressly stated herein.

[0025] Example: As attached Figure 1 To be continued Figure 8 As shown: This invention provides a portable and stable urine protein qualitative detection kit, comprising: a kit body 1; a homogenizing tank 2 fixedly installed at the front end of the kit body 1, a delivery tube 201 passing through the middle of ... The umbrella-shaped inclined surface of 06 is fitted with the conical groove of the limiting sleeve 204. A spring A207 is sleeved on the lower middle position of the umbrella-shaped plug A206. The top position of the spring A207 is fitted with the lower umbrella-shaped position of the umbrella-shaped plug A206. The bottom position of the spring A207 is fitted with the top position of the Y-shaped frame A205. A transverse groove is provided at the middle position of the top of the umbrella-shaped plug A206. A transmission frame 401 is symmetrically slidably connected to the left and right sides of the top of the limiting frame 4. A spring C402 is sleeved on the outer end of each transmission frame 401 and the sliding position of the limiting frame 4. Two reset pieces 404 are rotatably connected to the left and right sides of the top of the limiting frame 4. A support foot 403 is provided on each side of the transmission frame 401, and each support foot 403 of the transmission frame 401 is inserted into a reset piece 404.

[0026] The reagent kit 1 has a counterweight 101 fixedly installed at the bottom rear position. The bottom of the counterweight 101 is fixedly connected to the top rear position of the base plate 102. The base plate 102 is located directly below the reagent kit 1. A partition 103 is provided in the middle of the inside of the reagent kit 1. A battery box 104 is provided in the front interior of the reagent kit 1. A motor 105 is provided in the upper part of the battery box 104. A placement slot is provided at the top rear position of the reagent kit 1. A test reagent 5 is placed in the placement slot of the reagent kit 1. The test reagent 5 is located behind the partition 103.

[0027] An annular frame 202 is fixedly installed in the upper middle part of the uniform tank 2. An annular gear 203 is rotatably connected to the inner part of the annular frame 202. The conveying pipe 201 passes through the middle part of the annular frame 202 and the annular gear 203. Six vertical plates are provided at the bottom of the annular gear 203. A bevel gear 208 is rotatably connected to the front end of the annular frame 202. The bevel gear 208 meshes with the front end of the top of the annular gear 203, and the front end of the bevel gear 208 is fixedly connected to the rotating shaft of the motor 105.

[0028] The bottom of the conveying pipe 201 is provided with an output sleeve 3. The lower part of the inside of the output sleeve 3 is provided with a conical groove. The upper part of the inside of the output sleeve 3 is fixedly installed with a Y-shaped frame B301. The lower part of the inside of the Y-shaped frame B301 is slidably connected with an umbrella-shaped plug B302. A sealing ring is provided on the inclined surface of the umbrella-shaped part of the umbrella-shaped plug B302. The inclined surface of the umbrella-shaped plug B302 fits against the conical groove of the output sleeve 3. A spring B303 is sleeved on the upper middle part of the umbrella-shaped plug B302. The bottom part of the spring B303 fits against the upper part of the umbrella-shaped part of the umbrella-shaped plug B302. The top part of the spring B303 fits against the bottom part of the Y-shaped frame B301.

[0029] When using: Place the reagent kit 1 on a horizontal platform. Use the bottom counterweight 101 and the base plate 102 to ensure that the reagent kit 1 is stable and does not shake. Use a syringe to draw the liquid sample to be tested. Slowly press the syringe vertically into the hollow area in the middle of the limiting frame 4, so that the tip of the syringe is inserted into the middle position of the four reset pieces 404. After the tip of the syringe contacts the transverse groove on the top of the umbrella-shaped plug A206, continue to apply downward pressure. The syringe pushes the umbrella-shaped plug A206 to compress the spring A207 and make it slide downward, so that the umbrella-shaped plug A206 is disengaged from the tapered groove of the limiting sleeve 204. Next, inject the extracted liquid sample into the inside of the delivery tube 201 through the syringe. After the liquid sample inside the syringe is injected, the spring A207 resets and pushes the umbrella-shaped plug A206 upward. Its umbrella-shaped inclined surface once again fits into the conical groove of the limiting sleeve 204 to form a seal. The support leg 403 of the transmission frame 401 resets under the action of the spring C402, driving the reset component 404 to reset synchronously. The reset force of the reset component 404 can pop the syringe that has not been removed in time upward, avoiding the syringe from being left in place for too long, which would cause the umbrella-shaped plug A206 and the conical groove of the limiting sleeve 204 to fail to fit quickly, allowing dust and other impurities to enter the delivery tube 201 and affect subsequent testing.

[0030] To ensure uniformity, the liquid sample entering the delivery tube 201 is fed into the homogenization tank 2 through the annular array through-holes in the delivery tube 201. When the power switch in the battery box 104 is turned on, the motor 105 shaft drives the front bevel gear 208 to rotate. The bevel gear 208 meshes with the annular gear 203, driving the annular gear 203 to make circular motion within the annular frame 202. The six vertical plates at the bottom of the annular gear 203 rotate inside the homogenization tank 2, homogenizing the liquid sample inside the homogenization tank 2 to facilitate subsequent sampling and testing. When it is necessary to test the liquid sample homogenized inside the delivery tube 201 and the homogenizing tank 2, the test reagent 5 is removed from the reagent kit 1 and placed at the bottom front of the reagent kit 1, with the rear end of the test reagent 5 in contact with the front end of the counterweight 101. At this time, the detection position of the test reagent 5 will be directly below the output sleeve 3. The user moves the test reagent 5 upward, and the detection position of the test reagent 5 will contact the bottom of the umbrella-shaped plug B302. As the test reagent 5 continues to move upward, it pushes the umbrella-shaped plug B302 against the Y-shaped frame. As B301 slides upward, spring B303 contracts, and the umbrella-shaped inclined surface of the umbrella-shaped plug B302 disengages from the conical groove of the output sleeve 3. The homogenized liquid sample is transferred to the detection position of the test reagent 5 through the gap between the umbrella-shaped plug B302 and the conical groove of the output sleeve 3 to complete the sampling. After sampling, the test reagent 5 is quickly removed from under the test reagent 1, and spring B303 quickly drives the umbrella-shaped plug B302 to reset, preventing the homogenized liquid sample inside the delivery tube 201 and the homogenizing tank 2 from leaking out. The qualitative result of urine protein is determined based on the colorimetric reaction of the test reagent 5.

[0031] The above are merely specific embodiments of this disclosure, but the scope of protection of this disclosure is not limited thereto. The scope of protection of this disclosure shall be determined by the scope of the claims.

Claims

1. A portable, stable urine protein qualitative detection kit, characterized in that, include: The reagent kit (1) has a uniform tank (2) fixedly installed at the front end of the reagent kit (1). A delivery tube (201) is connected to the middle of the uniform tank (2). The delivery tube (201) has a ring array of through holes on its surface inside the uniform tank (2). A limiting sleeve (204) is fixedly connected to the top of the delivery tube (201). A conical groove is provided at the upper part of the inside of the limiting sleeve (204). A limiting frame (4) with a hollow design is fixedly connected to the middle of the top of the limiting sleeve (204). A Y-shaped frame A (205) is fixedly installed at the lower part of the inside of the limiting sleeve (204). An umbrella-shaped plug A (206) is slidably connected to the upper part of the inside of the Y-shaped frame A (205). A sealing ring is provided on the inclined surface of the umbrella-shaped part of the umbrella-shaped plug A (206). The inclined surface of the umbrella-shaped part of the umbrella-shaped plug A (206) fits the limiting sleeve. (204) has a conical groove, and a spring A (207) is sleeved on the lower middle position of the umbrella-shaped plug A (206). The top position of the spring A (207) is in contact with the lower umbrella position of the umbrella-shaped plug A (206), and the bottom position of the spring A (207) is in contact with the top position of the Y-shaped frame A (205). A transverse groove is provided at the middle position of the top of the umbrella-shaped plug A (206). A transmission frame (401) is symmetrically slidably connected to the left and right sides of the top of the limiting frame (4). A spring C (402) is sleeved on the outer end of the sliding position of each transmission frame (401) and the limiting frame (4). Two reset pieces (404) are rotatably connected to the left and right sides of the top of the limiting frame (4). A support foot (403) is provided on each side of the transmission frame (401), and the support foot (403) of each transmission frame (401) is inserted into a reset piece (404). An annular frame (202) is fixedly installed in the upper middle position inside the uniform tank (2). An annular gear (203) is rotatably connected inside the annular frame (202). The conveying pipe (201) passes through the middle position between the annular frame (202) and the annular gear (203). Six vertical plates are provided at the bottom position of the annular gear (203). The inner front end of the ring frame (202) is rotatably connected to a bevel gear (208), which meshes with the top front end of the ring gear (203), and the front end of the bevel gear (208) is fixedly connected to the motor (105) shaft.

2. The portable, stable urine protein qualitative detection kit as described in claim 1, characterized in that: A counterweight (101) is fixedly installed at the bottom rear of the reagent kit (1). The bottom of the counterweight (101) is fixedly connected to the top rear of the base plate (102). The base plate (102) is located directly below the reagent kit (1). A partition (103) is provided in the middle of the inside of the reagent kit (1).

3. The portable, stable urine protein qualitative detection kit as described in claim 2, characterized in that: A battery box (104) is provided inside the front end of the reagent kit (1), and a motor (105) is provided above the inside of the battery box (104). A placement slot is provided at the rear top of the reagent kit (1), and a test reagent (5) is placed in the placement slot of the reagent kit (1). The test reagent (5) is located behind the partition (103).

4. The portable, stable urine protein qualitative detection kit as described in claim 1, characterized in that: The bottom of the conveying pipe (201) is provided with an output sleeve (3), and a tapered groove is provided inside the lower part of the output sleeve (3). A Y-shaped frame B (301) is fixedly installed inside the upper part of the output sleeve (3). An umbrella-shaped plug B (302) is slidably connected inside the lower part of the Y-shaped frame B (301). A sealing ring is provided on the inclined surface of the umbrella-shaped part of the umbrella-shaped plug B (302).

5. The portable, stable urine protein qualitative detection kit as described in claim 4, characterized in that: The umbrella-shaped bevel of the umbrella-shaped plug B (302) is in contact with the conical groove of the output sleeve (3). A spring B (303) is sleeved on the upper middle position of the umbrella-shaped plug B (302). The bottom position of the spring B (303) is in contact with the upper umbrella position of the umbrella-shaped plug B (302). The top position of the spring B (303) is in contact with the bottom position of the Y-shaped frame B (301).

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