Vascular occlusion device effective to avoid the pterygopalatine artery in a mcao model

Abstract

The application discloses a blood vessel blocking device capable of effectively avoiding pterygopalatine arteries in an MCAO model, which comprises a clamping piece, a telescopic piece and a blocking block, one end of the telescopic piece is fixedly arranged on the clamping piece, and the other end of the telescopic piece is fixedly arranged with the blocking block. The purpose is to provide a blood vessel blocking device capable of effectively avoiding pterygopalatine arteries in an MCAO model, which can block the pterygopalatine arteries in the establishment of the MCAO model, so that the line plug head avoids entering the pterygopalatine arteries when moving to the intersection of the internal carotid artery and the pterygopalatine arteries, thereby effectively avoiding the pterygopalatine arteries and moving along the internal carotid artery only, and thus the MCAO model can be successfully established.

Description

Technical Field

[0001] This invention relates to the field of medical devices, and in particular to a vascular occlusion device that can effectively avoid pterygopalatine artery occlusion in MCAO model establishment. Background Technology

[0002] like Figure 1 As shown, in the prior art, when establishing a mouse / large MCAO model using the suture occlusion method, the suture 05 enters the internal carotid artery 03 from the external carotid artery 02 (the common carotid artery 01 divides into the external carotid artery 02 and the internal carotid artery 03 towards the head), and then moves towards the anterior cerebral artery and the middle cerebral artery. When the suture head 06 moves to the intersection of the internal carotid artery 03 and the pterygopalatine artery 04, the suture head 06 can easily enter the pterygopalatine artery 04, causing the model to fail to be established. This is because only when the suture head 06 enters the internal carotid artery 03 after passing through the above-mentioned intersection and continues to move along the internal carotid artery 03 can it reach the intersection of the anterior cerebral artery and the middle cerebral artery, thereby blocking the anterior cerebral artery and the middle cerebral artery, so that the model can be successfully established. Summary of the Invention

[0003] The technical problem to be solved by the present invention is to provide a vascular occlusion device that effectively avoids the pterygopalatine artery in MCAO model. It can block the pterygopalatine artery during the establishment of MCAO model, so that when the suture head moves to the intersection of the internal carotid artery and the pterygopalatine artery, it avoids entering the pterygopalatine artery, thereby effectively avoiding the pterygopalatine artery and moving only along the internal carotid artery, thus enabling the successful establishment of MCAO model.

[0004] The vascular obstruction device that effectively avoids the pterygopalatine artery in the MCAO model of the present invention includes a clamping member, a telescopic member, and an obstruction block. One end of the telescopic member is fixedly mounted on the clamping member, and the other end of the telescopic member is fixedly mounted on the obstruction block.

[0005] The present invention provides a device for effectively avoiding vascular occlusion of the pterygopalatine artery in the MCAO model, wherein the clamping element is a hemostatic clamp, the hemostatic clamp includes a handle, one end of the handle is fixedly connected to a first arm and a second arm, the first arm and the second arm are arranged opposite to each other and spaced apart, the end of the first arm away from the handle is fixedly connected to a third arm, the end of the second arm away from the handle is fixedly connected to a fourth arm, the end of the third arm away from the first arm extends toward the second arm, the end of the fourth arm away from the second arm extends toward the first arm, the third arm and the fourth arm are arranged crosswise, the end of the third arm away from the first arm is fixedly connected to a fifth arm, the end of the fourth arm away from the second arm is fixedly connected to a sixth arm, and the fifth arm and the sixth arm abut against each other.

[0006] The MCAO model of the present invention has a device for effectively avoiding vascular obstruction of the pterygopalatine artery, wherein the fifth arm is provided with a first clamping tooth on the side that abuts against the sixth arm, and the sixth arm is provided with a second clamping tooth on the side that abuts against the fifth arm, and the first clamping tooth and the second clamping tooth mesh with each other.

[0007] The present invention provides a device for effectively avoiding vascular obstruction of the pterygopalatine artery in the MCAO model, wherein a support plate is fixedly provided at one end of the telescopic member and the clamping member, and a collar is fixedly provided on the support plate, and the collar is fitted onto the handle of the hemostatic clamp.

[0008] The MCAO model of the present invention provides a vascular occlusion device that effectively avoids the pterygopalatine artery. The occlusion block has an occlusion surface at the end away from the telescopic member, and the occlusion block also has a receiving groove. One end of the receiving groove starts at the occlusion surface, and the other end of the receiving groove ends at the end of the occlusion block near the telescopic member.

[0009] The MCAO model of the present invention provides a vascular occlusion device that effectively avoids the pterygopalatine artery, wherein the occlusion surface is an arc-shaped surface, the receiving groove is an arc-shaped groove, and the receiving groove is a groove of equal depth or the depth of the receiving groove gradually increases along the direction from the occlusion surface to the end of the occlusion block near the telescopic member.

[0010] The present invention discloses a vascular occlusion device in the MCAO model that effectively avoids the pterygopalatine artery. The occlusion block is a cuboid block with a first end and a second end along its length. The first end is fixedly connected to a telescopic member. The connection between the second end face of the occlusion block and one side of the first and second ends is chamfered to form an arc-shaped surface that serves as the occlusion surface. A receiving groove is provided on the one side, and the other end of the receiving groove terminates at the first end of the occlusion block. The depth of the receiving groove is equal or gradually increases along the direction from the occlusion surface to the first end.

[0011] The present invention provides a device for effectively avoiding vascular obstruction of the pterygopalatine artery in the MCAO model, wherein one end of the telescopic member is fixedly connected to one end of the first sleeve, the other end of the first sleeve is fixedly connected to one side of the support plate, and a collar is fixedly provided on the other side of the support plate.

[0012] The present invention provides a vascular obstruction device in the MCAO model that effectively avoids the pterygopalatine artery. The telescopic member is fixedly connected to one end of a second sleeve at one end of the blockage block, and the other end of the second sleeve is fixedly connected to the first end of the blockage block. The wall of the second sleeve is axially broken to form an opening, and the opening is arranged in the direction of the receiving groove.

[0013] The MCAO model of the present invention includes a device that effectively avoids vascular occlusion of the pterygopalatine artery, wherein the telescopic component is a telescopic plastic corrugated tube or a telescopic metal corrugated tube.

[0014] The vascular occlusion device in this invention that effectively avoids the pterygopalatine artery in the MCAO model differs from existing technologies in that, during use, the clamping member is fixed to the common carotid artery of the mouse / mice, with the telescopic member in a compressed state. Pulling the telescopic member lengthens it, causing the occlusion block to move towards the intersection of the pterygopalatine artery and the internal carotid artery, ultimately abutting against the end of the pterygopalatine artery connecting to the internal carotid artery. Further stretching of the telescopic member then compresses the pterygopalatine artery, effectively closing it from the outside. At this point, the suture head, when moving to the intersection of the pterygopalatine artery and the internal carotid artery, will not enter the pterygopalatine artery but will easily enter the internal carotid artery, thus facilitating model establishment. Therefore, this invention can effectively occlude the pterygopalatine artery during MCAO model establishment, preventing the suture head from entering the pterygopalatine artery when moving to the intersection of the internal carotid artery and the pterygopalatine artery, thus effectively avoiding the pterygopalatine artery and moving only along the internal carotid artery, thereby successfully establishing the MCAO model.

[0015] The invention will now be further described with reference to the accompanying drawings. Attached Figure Description

[0016] Figure 1 This is a schematic diagram illustrating the accidental insertion of the head of a thrombus into the pterygopalatine artery during the establishment of existing large / small mouse MCAO models.

[0017] Figure 2 This is a front view of the vascular obstruction device that effectively avoids the pterygopalatine artery in the MCAO model of the present invention;

[0018] Figure 3 This is a front view of the MCAO model of the present invention after the hemostatic clip is hidden from the vascular occlusion device that effectively avoids the pterygopalatine artery.

[0019] Figure 4 for Figure 3 The left view;

[0020] Figure 5 This is a perspective view of the blocking block in this invention;

[0021] Figure 6 This is another perspective view of the blocking block in this invention;

[0022] Figure 7 This is a perspective view of the blocking block and the second sleeve in this invention;

[0023] Figure 8 This is a front view of the hemostatic clip of the present invention;

[0024] Figure 9 This is a top view of the hemostatic clip in the present invention (the hemostatic clip is in a closed state);

[0025] Figure 10 This is a top view of the hemostatic clip in the present invention (the hemostatic clip is in the open state);

[0026] Figure 11 This is a diagram showing the usage status of the vascular occlusion device that effectively avoids the pterygopalatine artery in the MCAO model of the present invention (the occlusion block does not block the pterygopalatine artery);

[0027] Figure 12 This is a diagram showing the usage status of the vascular occlusion device that effectively avoids the pterygopalatine artery in the MCAO model of the present invention (the occlusion block occludes the pterygopalatine artery).

[0028] Figure reference numerals:

[0029] 01. Common carotid artery; 02. External carotid artery; 03. Internal carotid artery; 04. Pterygopalatine artery; 05. Thread embolism; 06. Thread embolism head; 07. Occlusion block; 08. Occlusion surface; 09. Second sleeve; 10. Telescopic component; 11. First sleeve; 12. Support plate; 13. Cuff; 14. Hemostatic clip; 15. Receiving groove; 16. Opening; 17. Ring hole; 18. Handle; 19. Second connecting arm; 20. Fourth connecting arm; 21. Third connecting arm; 22. Fifth connecting arm; 23. First connecting arm; 24. Sixth connecting arm; 25. First clamping tooth; 26. Second clamping tooth. Detailed Implementation

[0030] like Figure 2 As shown, and in combination Figure 3-12 As shown, the vascular occlusion device that effectively avoids the pterygopalatine artery 04 in the MCAO model of the present invention includes a clamping member, a telescopic member 10 and an occlusion block 07. One end of the telescopic member 10 is fixedly mounted on the clamping member, and the other end of the telescopic member 10 is fixedly mounted with the occlusion block 07.

[0031] like Figure 8-10As shown, the MCAO model of the present invention effectively avoids vascular occlusion of the pterygopalatine artery 04. The clamping element is a hemostatic clip 14, which includes a handle 18. One end of the handle 18 (left end in the figure) is fixedly connected to a first connecting arm 23 and a second connecting arm 19. The first connecting arm 23 and the second connecting arm 19 are arranged opposite to each other and spaced apart. The end of the first connecting arm 23 away from the handle 18 (left end in the figure) is fixedly connected to a third connecting arm 21. The end of the second connecting arm 19 away from the handle 18 (left end in the figure) is fixedly connected to a third connecting arm 21. A fourth connecting arm 20 is fixedly connected to the third connecting arm 21. The end of the third connecting arm 21 away from the first connecting arm 23 extends toward the second connecting arm 19. The end of the fourth connecting arm 20 away from the second connecting arm 19 extends toward the first connecting arm 23. The third connecting arm 21 and the fourth connecting arm 20 are arranged crosswise. The end of the third connecting arm 21 away from the first connecting arm 23 is fixedly connected to a fifth connecting arm 22. The end of the fourth connecting arm 20 away from the second connecting arm 19 is fixedly connected to a sixth connecting arm 24. The fifth connecting arm 22 and the sixth connecting arm 24 abut against each other.

[0032] The gap between the first connecting arm 23 and the second connecting arm 19 increases as they are further away from the handle 18, that is, as... Figure 9 , 10 As shown, the gap between the first connecting arm 23 and the second connecting arm 19 gradually increases from right to left, thus forming a V-shaped structure together with the first connecting arm 23, the handle 18, and the second connecting arm 19. The third connecting arm 21 and the fourth connecting arm 20 are arranged in a cross pattern, as shown... Figure 9 , 10 As shown, the third connecting arm 21 and the fourth connecting arm 20 are arranged in an X-shape.

[0033] according to Figure 9 , 10 In terms of vertical and horizontal orientation, the right ends of the first connecting arm 23 and the second connecting arm 19 are both fixedly connected to the left end of the handle 18, and the first connecting arm 23 is located above the second connecting arm 19. The right end of the third connecting arm 21 is fixedly connected to the left end of the first connecting arm 23, and the left end of the third connecting arm 21 extends downward to the left. The right end of the fourth connecting arm 20 is fixedly connected to the left end of the second connecting arm 19, and the left end of the fourth connecting arm 20 extends upward to the left. Since the left end of the third connecting arm 21 extends downward to the left, while the left end of the fourth connecting arm 20 extends upward to the left, the two are arranged in a cross pattern. Finally, the left end of the third connecting arm 21 (i.e., the end away from the first connecting arm 23) is located below the left end of the fourth connecting arm 20 (i.e., the end away from the second connecting arm 19). After that, the left end of the third connecting arm 21 is fixedly connected to the fifth connecting arm 22, and the left end of the fourth connecting arm 20 is fixedly connected to the sixth connecting arm 24. The fifth connecting arm 22 and the sixth connecting arm 24 are both arranged in the left-right direction. Since the left end of the third link 21, which connects to the fifth link 22, is located below the left end of the fourth link 20, which connects to the sixth link 24, the fifth link 22 is located below the sixth link 24 and the two abut against each other.

[0034] The hemostatic clip 14 is made entirely of elastic metal. In its initial state, there is a certain opening force between the first connecting arm 23 and the second connecting arm 19. Thus, the first connecting arm 23, through the third connecting arm 21, tends to move the fifth connecting arm 22 upwards, while the second connecting arm 19, through the fourth connecting arm 20, tends to move the sixth connecting arm 24 downwards. The fifth connecting arm 22 is located below the sixth connecting arm 24, and the two are in contact. The upward movement of the fifth connecting arm 22 tends to move closer to the sixth connecting arm 24, and the downward movement of the sixth connecting arm 24 tends to move closer to the fifth connecting arm 22. In other words, the fifth connecting arm 22 and the sixth connecting arm 24 tend to move towards each other, thus bringing them together tightly. At this point, the hemostatic clip 14 is in a closed state. Figure 9 As shown.

[0035] When the hemostatic clip 14 needs to open, the first connecting arm 23 and the second connecting arm 19 move closer to each other, that is, the first connecting arm 23 moves downward and the second connecting arm 19 moves upward. In this way, the first connecting arm 23, through the third connecting arm 21, drives the fifth connecting arm 22 downward, and the second connecting arm 19, through the fourth connecting arm 20, drives the sixth connecting arm 24 upward. Since the fifth connecting arm 22 is below the sixth connecting arm 24, the fifth connecting arm 22 and the sixth connecting arm 24 move away from each other. At this time, the hemostatic clip 14 is in the open state. Figure 10 As shown.

[0036] like Figure 9 , 10 As shown, the MCAO model of the present invention effectively avoids vascular occlusion of the pterygopalatine artery 04. The fifth connecting arm 22 has a first clamping tooth 25 on its side abutting against the sixth connecting arm 24, and the sixth connecting arm 24 has a second clamping tooth 26 on its side abutting against the fifth connecting arm 22. The first clamping tooth 25 and the second clamping tooth 26 mesh with each other. Figure 8 As shown, the purpose of the first clamping tooth 25 and the second clamping tooth 26 is to enhance the clamping effect of the hemostatic clip 14. In order to facilitate the operation of the hemostatic clip 14, anti-slip texture is provided on the side of the first connecting arm 23 away from the second connecting arm 19, and anti-slip texture is also provided on the side of the second connecting arm 19 away from the first connecting arm 23.

[0037] like Figure 2 , 3As shown in Figure 4, the MCAO model of the present invention effectively avoids the vascular obstruction device of the pterygopalatine artery 04. A support plate 12 is fixedly mounted on one end of the telescopic member 10 that is fixed to the clamping member (lower end in the figure). The support plate 12 is a square, circular, or elliptical plate structure. A collar 13 is fixedly mounted on the support plate 12. The collar 13 is fixedly fitted onto the handle 18 of the hemostatic clamp 14, thereby fixing the telescopic member 10 to the hemostatic clamp 14 (i.e., the clamping member), and further fixing the telescopic member 10 and the obstruction block 07 onto the hemostatic clamp 14. The collar 13 is fixedly fitted onto the handle 18 of the hemostatic clamp 14 through its own annular hole 17, the shape of which matches the shape of the handle 18.

[0038] The specific connection method between the telescopic component 10 and the bearing plate 12 is as follows: one end of the first sleeve 11 (upper end in the figure) is fixedly connected to the clamping component at one end of the telescopic component 10, and the other end of the first sleeve 11 (lower end in the figure) is fixedly connected to one side (upper side in the figure) of the bearing plate 12. A collar 13 is fixedly provided on the other side (lower side in the figure) of the bearing plate 12.

[0039] like Figure 5 , 6 As shown in Figure 7, and in conjunction with Figure 2-4 As shown, the MCAO model of the present invention effectively avoids the pterygopalatine artery 04 vascular occlusion device, wherein the occlusion block 07 has an occlusion surface 08 at the end away from the telescopic member 10 (upper end of the figure), and the occlusion block 07 is also provided with a receiving groove 15, one end of the receiving groove 15 starts at the occlusion surface 08, and the other end of the receiving groove 15 terminates at the end of the occlusion block 07 near the telescopic member 10 (lower end of the figure).

[0040] The vascular occlusion device in the MCAO model of this invention effectively avoids the pterygopalatine artery 04, wherein the occlusion surface 08 is an arc-shaped surface and the receiving groove 15 is an arc-shaped groove. For example... Figure 6 As shown, the receiving groove 15 is a groove of uniform depth, meaning that the depth of the receiving groove 15 is equal along the direction from the blocking surface 08 to the end of the blocking block 07 near the telescopic member 10; that is, the depth of the receiving groove 15 is equal along the direction from top to bottom. Alternatively, as... Figure 5 As shown, the receiving groove 15 can also be a variable depth groove, that is, the depth of the receiving groove 15 gradually increases along the direction from the blocking surface 08 to the end of the blocking block 07 near the telescopic member 10, that is, the depth of the receiving groove 15 gradually increases along the direction from top to bottom.

[0041] The MCAO model of this invention includes a vascular occlusion device that effectively avoids the pterygopalatine artery 04. The occlusion block 07 is a cuboid block with a first end (lower end in the figure) and a second end (upper end in the figure) along its length. The first end is fixedly connected to the telescopic member 10. The connection between the second end face of the occlusion block 07 and one side of the first and second ends is chamfered to form an arc-shaped surface, serving as the occlusion surface 08. A receiving groove 15 is provided on this side. The other end of the receiving groove 15 terminates at the first end of the occlusion block 07. The depth of the receiving groove 15 is either equal or gradually increases along the direction from the occlusion surface 08 to the first end. The first end of the occlusion block 07 is the end of the occlusion block 07 closest to the telescopic member 10. The depth of the receiving groove 15 is equal along the direction from the occlusion surface 08 to the first end, i.e., the receiving groove 15 is a uniform depth groove; while the depth of the receiving groove 15 gradually increases along the direction from the occlusion surface 08 to the first end, i.e., the receiving groove 15 is a variable depth groove.

[0042] Since the blocking block 07 is a cuboid, it has four sides between the first and second ends. The connection between the second end face and one of the four sides is chamfered to form an arc-shaped surface, which is the blocking surface 08. A receiving groove 15 is provided on the side face chamfered to the second end face. Figure 11 , 12 As shown, the blocking surface 08 is used to compress the pterygopalatine artery 04 from the outside, thereby blocking the pterygopalatine artery 04. To prevent the blocking surface 08 from damaging the pterygopalatine artery 04 when compressing it, the blocking surface 08 is designed as an arc-shaped surface. When the blocking block 07 compresses the pterygopalatine artery 04, the side of the receiving groove 15 of the blocking block 07 faces the internal carotid artery 03. Thus, due to the presence of the receiving groove 15, the receiving groove 15 can accommodate the internal carotid artery 03 below the pterygopalatine artery 04, preventing the blocking block 07 from compressing the internal carotid artery 03 at that location.

[0043] like Figure 7 As shown, and in combination Figure 2-4 As shown, the MCAO model of the present invention effectively avoids the pterygopalatine artery 04 vascular obstruction device, wherein the telescopic member 10 is fixedly connected to one end (the upper end of the figure) of the second sleeve 09 at one end (the lower end of the figure) of the obstruction block 07, and the other end (the upper end of the figure) of the second sleeve 09 is fixedly connected to the first end (the lower end of the figure) of the obstruction block 07. The cylinder wall of the second sleeve 09 is broken along the axial direction (i.e., along the vertical direction of the figure) to form an opening 16, and the opening 16 is arranged in the direction of the receiving groove 15.

[0044] In this embodiment, the second sleeve 09 is a square tube, and the opening 16 is obtained by removing one side wall of the square tube. The opening 16 is arranged facing the receiving groove 15 so that when the blocking block 07 blocks the pterygopalatine artery 04, the second sleeve 09 will not block the pterygopalatine artery 04 in the receiving groove 15.

[0045] The MCAO model of this invention includes a device that effectively avoids vascular occlusion of the pterygopalatine artery 04, wherein the telescopic member 10 is a telescopic plastic corrugated tube or a telescopic metal corrugated tube. In the initial state, the telescopic member 10 is in a compressed state. After stretching the telescopic member 10, the telescopic member 10 has a certain strength, that is, it can maintain this stretched state. If the telescopic member 10 is compressed again with a larger force, the telescopic member 10 can be compressed back to the initial compressed state.

[0046] like Figure 11 , 12As shown, the vascular occlusion device that effectively avoids the pterygopalatine artery 04 in the MCAO model of this invention differs from the prior art in that, during use, the clamping member is fixed to the common carotid artery 01 of the mouse / greater mouse. Specifically, the hemostatic clamp 14 is held by hand, and the first connecting arm 23 and the second connecting arm 19 are moved closer to each other, thereby putting the hemostatic clamp 14 in an open state. At this time, there is a gap between the fifth connecting arm 22 and the sixth connecting arm 24. Then, the fifth connecting arm 22 and the sixth connecting arm 24 are respectively placed on... On both sides of the common carotid artery 01, that is, when the common carotid artery 01 is located between the fifth link 22 and the sixth link 24, the hemostatic clamp 14 is then released, and the first link 23 and the second link 19 move away from each other, while the fifth link 22 and the sixth link 24 move closer to each other until the fifth link 22 and the sixth link 24 clamp the common carotid artery 01. At this time, the side of the receiving groove 15 of the blocking block 07 is arranged towards the common carotid artery 01 and the internal carotid artery 03, that is, towards the fifth link 22 and the sixth link 24, that is, towards the left side of the figure. At this point, the telescopic member 10 is in a compressed state. Then, pulling the telescopic member 10 lengthens it, causing the blocking block 07 to move towards the intersection of the pterygopalatine artery 04 and the internal carotid artery 03, eventually abutting against the end of the pterygopalatine artery 04 connected to the internal carotid artery 03. That is, the blocking surface 08 of the blocking block 07 abuts against the pterygopalatine artery 04. Then, the telescopic member 10 is further stretched, causing the blocking block 07 to compress and close the pterygopalatine artery 04, effectively shutting it off from the outside. At this time, when the suture head 06 moves to the intersection of the pterygopalatine artery 04 and the internal carotid artery 03, it will not enter the pterygopalatine artery 04, but will easily enter the internal carotid artery 03, thus facilitating model creation. Therefore, this invention can block the pterygopalatine artery 04 during MCAO model creation, preventing the suture head 06 from entering the pterygopalatine artery 04 when it moves to the intersection of the internal carotid artery 03 and the pterygopalatine artery 04, thus effectively avoiding the pterygopalatine artery 04 and moving only along the internal carotid artery 03, thereby successfully creating the MCAO model.

[0047] As described above, when the occlusion block 07 compresses the pterygopalatine artery 04, since the receiving groove 15 is arranged towards the internal carotid artery 03, therefore... Figure 12 As shown, the internal carotid artery 03 below the pterygopalatine artery 04 can be located within the receiving groove 15, preventing the blocking block 07 from compressing the internal carotid artery 03 at that location. The second sleeve 09 below the blocking block 07 has an opening 16, so the second sleeve 09 will also not compress the internal carotid artery 03 within the receiving groove 15.

[0048] It should be noted that during the establishment of the mouse / greater MCAO model, only the common carotid artery 01, external carotid artery 02, and part of the internal carotid artery 03 near the common carotid artery 01 of the mouse / greater MCAO model are exposed. Therefore, the surgeon can directly clamp the hemostatic clip 14 on the common carotid artery 01. However, for the remaining subsequent operations, the surgeon can only perform blind operations based on experience, because the intersection of the internal carotid artery 03 and the pterygopalatine artery 04 of the mouse / greater MCAO model is not exposed.

[0049] After the thrombus head 06 successfully enters the internal carotid artery 03, avoiding the pterygopalatine artery 04, the compression telescopic member 10 is compressed again, and the occlusion block 07 no longer compresses the pterygopalatine artery 04. Then, the hemostatic clamp 14 is opened so that the fifth link 22 and the sixth link 24 no longer clamp the common carotid artery 01. After that, the invention is withdrawn, and the subsequent operations for establishing the large / mouse MCAO model can be carried out.

[0050] In this embodiment, as Figure 5 , 6 As shown, the length L of the blocking block 07 is 5 mm, the width W is 3 mm, and the height H is 2 mm. The length of the blocking block 07 is arranged vertically. As described above, the two ends of the blocking block 07 along its length are the first end and the second end, respectively. The end face of the first end is the side formed by the lower wide side and the upper high side, and the end face of the second end is the side formed by the upper wide side and the upper high side. The four sides between the first end and the second end are two sides formed by the long side and the wide side, and two sides formed by the long side and the high side. The side on which the receiving groove 15 is provided is one of the two sides formed by the long side and the wide side.

[0051] It should be noted that the terms "center", "upper", "lower", "front", "rear", "left", "right", "middle", etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on the present invention.

[0052] In the description of this invention, it should be noted that, unless otherwise explicitly specified and limited, the terms "connected" and "linked" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium. Those skilled in the art can understand the specific meaning of the above terms in this invention based on the specific circumstances.

[0053] The embodiments described above are merely preferred embodiments of the present invention and are not intended to limit the scope of the present invention. Various modifications and improvements made by those skilled in the art to the technical solutions of the present invention without departing from the spirit of the present invention should fall within the protection scope defined by the claims of the present invention.

Claims

1. A vascular occlusion device for effectively avoiding the pterygopalatine artery in an MCAO model, characterized in that: The vascular occlusion device includes a clamping member, a telescopic member, and an occlusion block. One end of the telescopic member is fixedly mounted on the clamping member, and the other end of the telescopic member is fixedly mounted on the occlusion block. The occlusion block has an occlusion surface at its end away from the telescopic member, and a receiving groove is also provided on the occlusion block. One end of the receiving groove starts at the occlusion surface, and the other end of the receiving groove terminates at the end of the occlusion block near the telescopic member. The clamping member is a hemostatic clamp, which includes a handle. One end of the handle is fixedly connected to a first connecting arm and a second connecting arm. The first and second connecting arms are arranged opposite to each other and spaced apart. A third connecting arm is fixedly connected to the end of the second connecting arm furthest from the handle. A fourth connecting arm is fixedly connected to the end of the second connecting arm furthest from the handle. The end of the third connecting arm furthest from the first connecting arm extends toward the second connecting arm, and the end of the fourth connecting arm furthest from the second connecting arm extends toward the first connecting arm. The third and fourth connecting arms are arranged alternately. A fifth connecting arm is fixedly connected to the end of the third connecting arm furthest from the first connecting arm, and a sixth connecting arm is fixedly connected to the end of the fourth connecting arm furthest from the second connecting arm. The fifth and sixth connecting arms abut against each other. The side of the fifth connecting arm that abuts against the sixth connecting arm has a [feature / detail]. The first clamping tooth; the sixth connecting arm has a second clamping tooth on its side that abuts against the fifth connecting arm, and the first clamping tooth and the second clamping tooth mesh with each other; a bearing plate is fixedly provided at one end of the telescopic member that is fixed to the clamping member, and a collar is fixedly provided on the bearing plate, the collar being fitted onto the handle of the hemostatic clamp; the blocking surface is an arc-shaped surface, the receiving groove is an arc-shaped groove, the receiving groove is a groove of equal depth or the depth of the receiving groove gradually increases along the direction from the blocking surface to the end of the blocking block near the telescopic member; the blocking block is a cuboid block, and the two ends of the blocking block along the length direction are respectively the first end and the second end. The first end is fixedly connected to the telescopic component. The connection between the second end face of the blocking block and one side of the first and second ends is chamfered to form an arc-shaped surface that serves as the blocking surface. A receiving groove is provided on one side, and the other end of the receiving groove terminates at the first end of the blocking block. The depth of the receiving groove is equal or gradually increases along the direction from the blocking surface to the first end. One end of the telescopic component is fixedly connected to one end of the first sleeve, and the other end of the first sleeve is fixedly connected to one side of the bearing plate. A collar is fixedly provided on the other side of the bearing plate. The telescopic component is fixedly connected to one end of the second sleeve at one end of the blocking block, and the other end of the second sleeve is fixedly connected to the first end of the blocking block. The cylinder wall of the second sleeve is broken along the axial direction to form an opening, and the opening is arranged in the direction of the receiving groove.

2. The vascular occlusion device for effectively avoiding the pterygopalatine artery in the MCAO model according to claim 1, characterized in that: The telescopic component is a telescopic plastic corrugated pipe or a telescopic metal corrugated pipe.

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