一种含烟酰胺和光甘草定的超分子美白组合物及其制备方法和应用
By encapsulating nicotinamide and glycyrrhizin with cyclodextrin to form a supramolecular complex, the solubility and stability issues in cosmetics are solved, enabling the application of cosmetics with synergistic whitening effects and high transparency.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- BEIJING SHANGJIE YOULAN TECH CO LTD
- Filing Date
- 2025-09-02
- Publication Date
- 2026-07-17
AI Technical Summary
Niacinamide and glycyrrhizin present challenges in cosmetics due to their contradictory solubility, conflicting stability, and different sites of action. Traditional encapsulation techniques struggle to efficiently encapsulate both ingredients simultaneously, leading to delayed whitening effects and the risk of skin irritation.
Cyclodextrin was used as a carrier to encapsulate nicotinamide and glycyrrhizin in its hydrophobic cavity. A stable supramolecular complex was formed through van der Waals forces, hydrogen bonds and π-π stacking interactions between the host and guest components. The preparation process was optimized to improve solubility and stability and achieve differences in release kinetics.
It improves the solubility and stability of niacinamide and glycyrrhizin, reduces skin irritation, achieves synergistic whitening effects, and is suitable for high-transparency cosmetic formulations.
Smart Images
Figure CN120837373B_ABST