Biomarker for MDS-EB2 diagnosis, detection product and application thereof

CN120847415APending Publication Date: 2025-10-28SHANGHAI UNIV OF T C M
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Patent Information

Application Number
CN202510783950.4
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-06-12
Publication Date
2025-10-28

AI Technical Summary

Technical Problem

Currently, there is a lack of specific bone marrow biomarkers for myelodysplastic syndromes (MDS), especially high-risk MDS-EB2, and existing detection methods do not involve IL-3.

Method used

Interleukin-3 (IL-3) was used as a biomarker for MDS-EB2. The level of IL-3 in bone marrow blood was detected to assist in diagnosis and assessment of drug efficacy, prognosis and treatment effect.

Benefits of technology

As a biomarker for MDS-EB2, IL-3 can significantly improve the relevance of diagnosis and simplify the detection process, providing more accurate diagnostic references and can be used to screen effective therapeutic drugs.

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Abstract

The invention relates to the field of biotechnology and medicine, and particularly provides IL-3 as a biomarker for diagnosing high-risk myelodysplastic syndrome (MDS EB2 typing). The research finds that the level of IL-3 in bone marrow blood of a patient with the myelodysplastic syndrome (MDS-EB2) is obviously higher than that of a healthy person, so that the IL-3 is used as a biomarker related to diagnosis, treatment and prognosis effects of the MDS-EB2 and is used for diagnosis or auxiliary diagnosis of the myelodysplastic syndrome; the detection reagent can be used for diagnosis and detection of MDS. Detection of the biomarker can provide reference for diagnosis of the high-risk myelodysplastic syndrome MDS-EB2, and the biomarker has a good application prospect.
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