Perfusate for ophthalmologic operation as well as preparation method and application of perfusate

CN120860050AInactive Publication Date: 2025-10-31SICHUAN ACADEMY OF MEDICAL SCI SICHUAN PROVINCIAL PEOPLES HOSPITAL
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Patent Information

Application Number
CN202511383443.8
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-09-26
Publication Date
2025-10-31
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention relates to the technical field of medicines, in particular to a perfusate for ophthalmologic operations and a preparation method and application thereof, and the perfusate for ophthalmologic operations is obtained by dissolving adenosine disodium triphosphate in a balanced salt solution. The perfusate for the ophthalmologic operation contains 0.01-10.00 mg / mL of disodium adenosine triphosphate, and on the basis that the osmotic pressure and the pH value of an original balanced salt solution are reserved, energy can be directly supplied to cells through the disodium adenosine triphosphate. In an anterior chamber perfusate, adenosine disodium triphosphate can directly supply energy to corneal endothelial cells, and the energy is used for Na < + > and K < + >-ATP enzymes to keep cornea in a dehydrated state during and after an operation, so that corneal edema is prevented; in a vitreous cavity perfusate, adenosine disodium triphosphate can directly supply energy to retinal nerve epithelium and pigment epithelium cells, light damage is reduced, and postoperative vision is improved.
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Citation Information

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