Perfusate for ophthalmologic operation as well as preparation method and application of perfusate
CN120860050AInactive Publication Date: 2025-10-31SICHUAN ACADEMY OF MEDICAL SCI SICHUAN PROVINCIAL PEOPLES HOSPITAL
Patent Information
- Application Number
- CN202511383443.8
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-09-26
- Publication Date
- 2025-10-31
- Estimated Expiration
- Not applicable · inactive patent
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Figure CN120860050A_ABST
Abstract
The invention relates to the technical field of medicines, in particular to a perfusate for ophthalmologic operations and a preparation method and application thereof, and the perfusate for ophthalmologic operations is obtained by dissolving adenosine disodium triphosphate in a balanced salt solution. The perfusate for the ophthalmologic operation contains 0.01-10.00 mg / mL of disodium adenosine triphosphate, and on the basis that the osmotic pressure and the pH value of an original balanced salt solution are reserved, energy can be directly supplied to cells through the disodium adenosine triphosphate. In an anterior chamber perfusate, adenosine disodium triphosphate can directly supply energy to corneal endothelial cells, and the energy is used for Na < + > and K < + >-ATP enzymes to keep cornea in a dehydrated state during and after an operation, so that corneal edema is prevented; in a vitreous cavity perfusate, adenosine disodium triphosphate can directly supply energy to retinal nerve epithelium and pigment epithelium cells, light damage is reduced, and postoperative vision is improved.
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Citation Information
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