Use of valtrin in the preparation of an anti-mycobacterium tuberculosis drug

CN120919098BActive Publication Date: 2026-06-09BEIJING CHEST HOSPITAL CAPITAL MEDICAL UNIV +1
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
BEIJING CHEST HOSPITAL CAPITAL MEDICAL UNIV
Filing Date
2025-10-14
Publication Date
2026-06-09

AI Technical Summary

Technical Problem

Existing anti-tuberculosis drugs have long treatment durations, significant side effects, and poor patient compliance. Multidrug-resistant tuberculosis has a low cure rate, and the development of new and effective drugs is progressing slowly, leading to severe challenges in tuberculosis treatment.

Method used

Valepotriate was used as the active ingredient to prepare an anti-tuberculosis drug. Its killing and antibacterial effects against Mycobacterium tuberculosis were verified through in vitro and in vivo experiments. The drug was then formulated with pharmaceutically acceptable excipients.

Benefits of technology

Valerianin exhibits significant anti-tuberculosis activity, has low cytotoxicity, and can effectively kill Mycobacterium tuberculosis, providing a new direction for the development of anti-tuberculosis drugs.

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Abstract

The application discloses application of valtrin in preparation of anti-mycobacterium tuberculosis drugs and relates to the technical field of bioengineering. 22 H 30 O8.The mycobacterium tuberculosis is mycobacterium tuberculosis H 37 Rv strain.The application discloses, for the first time, that valtrin is a compound of natural origin, has the dual advantages of high efficiency and low toxicity, has obvious anti-mycobacterium tuberculosis effect, provides a new candidate drug scheme with great development potential for solving the treatment predicament of tuberculosis, and has great scientific value and application prospect.
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