A liquid chromatography sample introduction device

Abstract

The application relates to the technical field of liquid chromatographs, in particular to a sample feeding device of a liquid chromatograph, which comprises a base, supporting legs are fixedly installed at the top of the four corners of the base, a top base is fixedly installed at the top of the supporting legs, and a sample storage mechanism is fixedly installed at the top of the top base. The application can be used to twist the adjusting handle, drive the guide block to rotate, make the adjusting plate move outward, further push the adjusting frame and the connecting shaft to move outward, make the limiting block shrink, make the limiting frame separate, and then the syringe can be taken out. Meanwhile, the elastic clamping frame can stably clamp the piston rod, the syringe can be conveniently disassembled, when the syringe is installed, the new syringe is inserted into the limiting frame, the adjusting handle is loosened, the limiting spring is reset, the limiting block is pushed to move inward, the syringe is clamped and positioned, the top of the piston rod is clamped through the elastic clamping frame, and the installation is completed. The design simplifies the operation process, improves the convenience, can quickly replace the syringe, and further simplifies the device operation.

Description

Technical Field

[0001] This application relates to the field of liquid chromatography technology, and in particular to a liquid chromatography injection device. Background Technology

[0002] The main injection device in liquid chromatography (LC) is the injector, whose function is to accurately deliver the sample solution into the chromatographic column. Currently, manual injectors require manual operation, using a syringe to draw a certain amount of sample solution and inject it into the LC's injection system. While this method is simple to operate, LC injection typically involves sample selection, sample extraction, and sample injection. A LC injector, by using multiple rotating sample holders for autonomous selection and employing electrically driven sliding rails for precise sample extraction, and finally using an electric pusher to advance the sample into the chromatograph for detection, can automate the injection process and improve the efficiency of the chromatograph.

[0003] A search revealed Chinese Patent Publication No. CN208568697U, which discloses an automatic sample injection device for a high-performance liquid chromatograph (HPLC). The device includes a base, a fixed base, and a volumetric aspiration mechanism. The fixed base is mounted on the base, and the volumetric aspiration mechanism is connected to the fixed base via a sampling support frame. A sample stage is positioned on the base corresponding to the volumetric aspiration mechanism. The volumetric aspiration mechanism includes a mounting plate, a sliding guide rail, a drive screw, and an injection assembly. The sliding guide rail and the drive screw are both vertically mounted on the sampling support frame. The mounting plate is slidably mounted within the sliding guide rail. The injection assembly is located on one side of the mounting plate, and the drive screw is located on the other side of the mounting plate and fixedly connected to it. The drive screw drives the mounting plate to move up and down within the sliding guide rail. The sample stage is rotatably connected to the base and has multiple slots for placing sample vials. These slots are arranged in a ring and are positioned opposite the injection assembly.

[0004] Regarding the aforementioned related technologies, the inventors have discovered the following drawbacks:

[0005] While the aforementioned device offers automated and selective sample introduction capabilities, it still has certain shortcomings in its practical application. Firstly, the syringe is fixed to the device, requiring cleaning or replacement after each sample introduction. However, the device cannot perform this cleaning and replacement, highlighting its limitations. Secondly, the single-syringe configuration makes it prone to contamination during multi-sample testing, potentially affecting detection accuracy. Therefore, improvements to the existing equipment are necessary. Summary of the Invention

[0006] To improve the overall ease of operation of this device, this application provides a liquid chromatography injection device.

[0007] This application provides a liquid chromatography injection device, which adopts the following technical solution: it includes a base, with support legs fixedly installed at the four corners of the top of the base, a top seat fixedly installed on the top of the support legs, a sample storage mechanism fixedly installed on the top of the top seat, a support frame fixedly installed on the rear side of the top of the top seat, a telescopic cylinder fixedly installed at the front end of the support frame, a first motor fixedly installed through the support frame at the bottom output end of the telescopic cylinder, a fixing block fixedly installed at the bottom output end of the first motor, sampling mechanisms fixedly installed at equal intervals on the outer side of the fixing block, and an injection tube fixedly installed in the middle of the rear side of the top seat;

[0008] The sampling mechanism includes side rails, which are fixedly installed at equal intervals on the outside of the fixed block. A displacement component is movably installed inside the side rails, and a clamping component is fixedly installed at the lower outer end of the side rails. A syringe is installed at the lower end of the side rails through the clamping component.

[0009] Optionally, the displacement assembly includes a second motor, which is fixedly mounted on the top of the side rail. A lead screw is fixedly mounted through the bottom output end of the second motor and is rotatably connected to the inside of the side rail. A sliding block is threadedly connected to the outer surface of the lead screw. An elastic clamping bracket is fixedly mounted on the outer side of the sliding block. A clamping bracket is fixedly mounted on the outer end of the elastic clamping bracket. The upper end of the piston rod of the syringe is clamped inside the clamping bracket.

[0010] Optionally, the clamping assembly includes a fixing frame, which is fixedly installed at the lower end of the side rail. Limiting springs are fixedly installed at both ends of the fixing frame. Limiting blocks are fixedly installed at the ends of the limiting springs. Limiting frames are fixedly installed on the outer side of the limiting blocks. The syringe is inserted between the inner sides of the limiting frames.

[0011] Optionally, a connecting shaft is fixedly installed at the outer end of the limiting block, and an adjusting bracket is fixedly installed at the outer end of the connecting shaft through the fixing frame.

[0012] Optionally, an adjustment plate is fixedly installed at the outer end of the adjustment frame, and a guide block is rotatably connected to the bottom of the side rail.

[0013] Optionally, an adjustment handle is fixedly installed at the bottom of the guide block, the guide block has an elliptical shape when viewed from below, and the outer side of the guide block and the inner side of the adjustment plate are fitted together.

[0014] Optionally, the sample storage mechanism includes a third motor, which is fixedly installed at the bottom front end of the top base. The output end of the third motor passes through the top base and is fixedly installed with a turntable. Limiting components are fixedly installed at equal intervals on the top of the turntable, and a sample dish is installed on the top of the turntable through the limiting components.

[0015] Optionally, the limiting component includes a fixing frame, which is fixedly installed on the outside of the turntable in a ring arrangement with equal spacing. Both ends of the inner side of the fixing frame are fixedly installed with telescopic springs. The inner end of the telescopic spring is fixedly installed with a movable block. The movable block is slidably connected to the inside of the fixing frame. The inner end of the movable block is fixedly installed with a clamping seat. The sample dish is inserted into the middle of the fixing frame and located between the inner sides of the clamping seats.

[0016] Optionally, the top of the turntable is provided with equally spaced receiving grooves, and the bottom of the sample dish is inserted into the receiving groove.

[0017] Optionally, the inner side of the clamping seat has a V-shaped top view, and the bottom of the turntable is rotatably connected with balls arranged in a ring at equal intervals, with the bottom of the balls and the top of the top seat in close contact.

[0018] In summary, this application includes the following beneficial technical effects:

[0019] 1. By setting up a sample storage mechanism, this device achieves flexible adaptation to sample dishes of different sizes. Utilizing the elasticity of a telescopic spring, the movable block slides inside the fixed frame, effectively clamping and fixing the sample dish. At the same time, the turntable is driven by a third motor to rotate, which can flexibly adjust the position of the sample dish to meet the sample injection requirements. During the sample injection process, the first motor can drive the fixed block to rotate, adjust the position of the syringe, avoid cross-contamination, and improve detection accuracy. In addition, the elastic clamping design of the telescopic spring facilitates quick and easy replacement of sample dishes, improving the ease of use of the device. Overall, this design not only improves the adaptability and ease of sample injection of the device, but also optimizes the operation process and improves work efficiency.

[0020] 2. By setting up a sampling mechanism, this device achieves automatic sample injection. When the sample dish is moved to the bottom of the syringe, the telescopic cylinder pushes the syringe downward, and the needle is inserted into the sample dish. Subsequently, the second motor drives the lead screw to rotate, causing the sliding block to slide in the side rail, pulling the piston rod upward to extract the sample. Then, the first motor drives the fixed block to rotate, and the syringe moves to the injection tube. Finally, the second motor drives the lead screw in the opposite direction, pushing the sliding block downward, and the piston rod presses down, pushing the sample into the injection tube. The entire process requires no manual intervention, improving the efficiency and accuracy of sample injection, realizing the automated operation of the device, and simplifying the experimental procedure.

[0021] 3. By incorporating a clamping assembly, this device enables rapid disassembly and replacement of the syringe. Twisting the adjusting handle pushes the guide block to rotate, causing the adjusting plate to move outward. This, in turn, pushes the adjusting frame and connecting shaft outward, causing the limiting block to retract and the limiting frame to separate, allowing the syringe to be withdrawn. Simultaneously, the elastic clamping frame stably engages the piston rod, facilitating disassembly. During installation, the new syringe is inserted into the limiting frame, the adjusting handle is released, the limiting spring returns to its original position, pushing the limiting block inward to clamp and position the syringe. The elastic clamping frame then engages the top of the piston rod, completing the installation. This design simplifies the operation process, improves ease of use, and enables rapid syringe replacement, further simplifying the operation of the device. Attached Figure Description

[0022] Figure 1 This is a schematic diagram of the overall structure in an embodiment of this application;

[0023] Figure 2 This is a top view of the structure in an embodiment of this application;

[0024] Figure 3 This is a schematic diagram of the structure viewed from below in an embodiment of this application;

[0025] Figure 4 This is a rear-view structural schematic diagram of an embodiment of this application;

[0026] Figure 5 This is a schematic diagram of the overall structure of the sample storage mechanism in the embodiments of this application;

[0027] Figure 6 This is a schematic diagram of the sample storage mechanism in an embodiment of this application, viewed from below.

[0028] Figure 7 This is a schematic diagram of the sampling mechanism in the embodiments of this application;

[0029] Figure 8 This is an embodiment of the present application. Figure 7 A magnified structural diagram at point A;

[0030] Figure 9 This is a bottom view of the sampling mechanism in an embodiment of this application.

[0031] Reference numerals: 1. Base; 2. Support leg; 3. Top seat; 4. Support frame; 5. Telescopic cylinder; 6. Sample storage mechanism; 61. Third motor; 62. Turntable; 63. Limiting component; 631. Fixing frame; 632. Telescopic spring; 633. Movable block; 634. Clamping seat; 635. Receiving groove; 636. Ball bearing; 64. Sample dish; 7. First motor; 8. Fixing block; 9. Sampling mechanism; 91. Side rail ; 92. Displacement assembly; 921. Second motor; 922. Lead screw; 923. Sliding block; 924. Elastic clamping bracket; 925. Clamping bracket; 93. Clamping assembly; 931. Fixing frame; 932. Limiting spring; 933. Limiting block; 934. Limiting frame; 935. Coupling shaft; 936. Adjusting frame; 937. Adjusting plate; 938. Guide block; 939. Adjusting handle; 94. Syringe; 10. Sample inlet tube. Detailed Implementation

[0032] The following is in conjunction with the appendix Figure 1-9 This application will be described in further detail.

[0033] This application discloses a liquid chromatography injection device. For example... Figure 1 As shown, the system includes a base 1, with support legs 2 fixedly installed at the four corners of the top of the base 1, a top seat 3 fixedly installed on the top of the support legs 2, a sample storage mechanism 6 fixedly installed on the top of the top seat 3, a support frame 4 fixedly installed on the rear side of the top of the top seat 3, a telescopic cylinder 5 fixedly installed at the front end of the support frame 4, a first motor 7 fixedly installed through the bottom output end of the telescopic cylinder 5, a fixing block 8 fixedly installed at the bottom output end of the first motor 7, sampling mechanisms 9 fixedly installed at equal intervals on the outer side of the fixing block 8, and a sample inlet tube 10 fixedly installed in the middle of the rear side of the top seat 3.

[0034] The sampling mechanism 9 includes side rails 91, which are fixedly installed at equal intervals on the outside of the fixing block 8. A displacement component 92 is movably installed inside the side rails 91. A clamping component 93 is fixedly installed at the lower outer end of the side rails 91, and a syringe 94 is installed at the lower end of the side rails 91 via the clamping component 93. A telescopic cylinder 5 is installed at the front end of the support frame 4 for precisely controlling the lifting and lowering of the syringe 94. The bottom of the telescopic cylinder 5 is connected to a first motor 7. The first motor 7 drives the sampling mechanisms 9, which are arranged at equal intervals on the outside, to move via the fixing block 8. These sampling mechanisms 9 are the core part of the sampling device, responsible for sample extraction and injection. In addition, an injection tube 10 is also provided in the middle of the rear side of the top seat 3 for... The design of the sampling mechanism 9 is particularly crucial for delivering the extracted sample into the liquid chromatography system. It includes a side rail 91, a displacement component 92, and a clamping component 93. The side rail 91 is fixedly installed on the outside of the fixed block 8, and the displacement component 92 moves inside the side rail 91 to precisely control the displacement of the syringe 94 between the sample dish 64 and the injection tube 10. The clamping component 93 is responsible for stably clamping the syringe 94, ensuring stability and accuracy during the sampling process. This injection device can realize automatic sample extraction and injection, improving the efficiency and accuracy of the experiment. At the same time, the design of the sampling mechanism 9 makes the replacement of the syringe 94 simple and quick, further improving the ease of use and flexibility of the device.

[0035] Please refer to Figure 9The displacement assembly 92 includes a second motor 921, which is fixedly mounted on the top of the side rail 91. A lead screw 922 is fixedly mounted on the bottom output end of the second motor 921, passing through the side rail 91. The lead screw 922 is rotatably connected to the interior of the side rail 91. A sliding block 923 is threaded onto the outer surface of the lead screw 922. An elastic clamping bracket 924 is fixedly mounted on the outer side of the sliding block 923. A clamping bracket 925 is fixedly mounted on the outer end of the elastic clamping bracket 924. The upper end of the piston rod of the syringe 94 is clamped inside the clamping bracket 925. Motor 921 is fixedly mounted on the top of side rail 91, serving as a drive source to provide power to the entire displacement assembly 92. When the second motor 921 starts, its bottom output end drives the lead screw 922 to rotate. The lead screw 922 is rotatably connected to the inside of side rail 91, ensuring the stability and accuracy of the lead screw 922 during rotation. A sliding block 923 is threadedly connected to the outer surface of the lead screw 922. This design allows the sliding block 923 to slide up and down along the lead screw 922 when it rotates. A flexible clamping bracket 924 is fixedly installed on the side. The flexible clamping bracket 924 has a certain degree of elasticity and recovery, and can deform under force and return to its original state after release. A clamping bracket 925 is fixedly installed on the outer end of the flexible clamping bracket 924. The clamping bracket 925 is used to fix the piston rod of the syringe 94. During the sampling process, when it is necessary to move the syringe 94, the second motor 921 is started, driving the lead screw 922 to rotate, which in turn drives the sliding block 923 to slide on the lead screw 922. The movement of the sliding block 923 will drive the flexible clamping bracket 924 to move. The frame 924 and the holder 925 move together to achieve the displacement of the syringe 94. Due to the design of the elastic mounting frame 924 and the holder 925, the piston rod of the syringe 94 can be stably engaged inside the holder 925, ensuring that it will not fall off or shake during the movement. This design of the displacement component 92 not only achieves the precise movement of the syringe 94, but also ensures the stability and reliability of the sampling process. At the same time, due to the use of motor drive and threaded transmission, the operation of the entire displacement component 92 is simpler and more efficient.

[0036] Please refer to Figure 9The clamping assembly 93 includes a fixed frame 931, which is fixedly installed at the lower end of the side rail 91. Limit springs 932 are fixedly installed at both ends of the fixed frame 931. Limit blocks 933 are fixedly installed at the ends of the limit springs 932, and limit frames 934 are fixedly installed on the outer sides of the limit blocks 933. A syringe 94 is inserted into the inner sides of the limit frames 934. The fixed frame 931, as the basic structure of the clamping assembly 93, is firmly installed at the lower end of the side rail 91, providing stable support for the entire assembly. A limit spring 932 is fixedly installed at both ends inside the fixed frame 931. The limit spring 932 has a certain elasticity and restoring force, and can deform when subjected to external force and return to its original state after the external force is removed. A limit block 933 is fixedly installed at the end of the limit spring 932. The limit block 933 and the limit spring 932 are closely connected to each other, forming an elastic clamping mechanism. When it is necessary to fix the syringe 94, the limit block 933 can move under the action of the limit spring 932. The syringe 94 is clamped on the outside by moving inward. The limit block 933 is fixedly mounted on the outside of the limit frame 934, which serves as a guide and positioner to ensure that the syringe 94 can be accurately inserted into the inner side of the limit frame 934. This design not only ensures the stability of the syringe 94, but also makes the installation and removal of the syringe 94 more convenient and quick. When it is necessary to install the syringe 94 onto the clamping assembly 93, simply insert the syringe 94 into the inner side of the limit frame 934, and then adjust the structure of the clamping assembly 93 so that the limit block 933 clamps the outside of the syringe 94 under the action of the limit spring 932. In this way, the syringe 94 is firmly fixed on the clamping assembly 93, and the sampling operation can begin. The clamping assembly 93 achieves stable clamping and positioning of the syringe 94 through the coordinated action of the fixed frame 931, the limit spring 932, the limit block 933, and the limit frame 934, thereby improving the sampling accuracy and operational reliability of the sampling device.

[0037] Please refer to Figure 9An adjusting plate 937 is fixedly mounted on the outer end of the adjusting frame 936, and a guide block 938 is rotatably connected to the bottom of the side rail 91. The adjusting plate 937 provides the operator with more control points and force application points, making it easier for them to operate when they need to adjust the position or clamping force of the syringe 94. Specifically, when the operator wants to adjust the clamping state or position of the syringe 94, they can apply appropriate force or rotate the adjusting plate 937, thereby achieving precise control of the limiting block 933 and the clamping force through the action of the adjusting frame 936 and the connecting shaft 935. In addition, a guide block 938 is rotatably connected to the bottom of the side rail 91. The guide block 938 is designed to ensure that the adjusting frame 936... The stability and accuracy of the adjusting plate 937 during movement are ensured by the guide block 938. When the adjusting plate 937 is subjected to external force, the guide block 938 guides it to move along a predetermined trajectory, preventing it from deviating from the track or causing unnecessary shaking. This not only helps to improve the structural stability of the entire clamping assembly 93, but also ensures the positional accuracy and operational reliability of the syringe 94 during the sampling process. The design of the adjusting plate 937 and the guide block 938 plays a crucial role in the clamping assembly 93 of the injection device. Together, they form a stable and adjustable clamping system, providing strong support for the stable clamping and precise control of the syringe 94. At the same time, this also reflects the refinement and humanization of the injection device design, aiming to improve the efficiency and accuracy of experimental operations.

[0038] Please refer to Figure 8A coupling 935 is fixedly installed on the outer end of the limiting block 933. An adjusting bracket 936 is fixedly installed on the outer end of the coupling 935 through the fixing frame 931. The coupling 935, as a key component connecting the limiting block 933 and the adjusting bracket 936, has its outer end passing through the fixing frame 931 and fixedly installed with the adjusting bracket 936. The adjusting bracket 936 allows the operator to adjust the position and clamping force of the limiting block 933 when it is necessary to disassemble or replace the syringe 94. Specifically, when it is necessary to release the syringe 94, the adjusting bracket 936 can be operated to move the coupling 935 outwards, thereby loosening the clamping force on the syringe 94; conversely, when it is necessary to release the syringe 94, the adjusting bracket 936 can be operated to move the limiting block 933 outwards, thereby loosening the clamping force on the syringe 94; conversely, when it is necessary to release the syringe 94, the adjusting bracket 936 can be operated to move the coupling 935 outwards, thereby loosening the clamping force on the syringe 94. When clamping the syringe 94, the limiting block 933 can be moved inward by adjusting the bracket 936 to increase the clamping force on the syringe 94. This design not only makes the installation and removal of the syringe 94 more convenient and quick, but also improves the adaptability and flexibility of the clamping assembly 93, enabling it to adapt to syringes 94 of different specifications and sizes. In addition, through the cooperation of the coupling 935 and the adjusting bracket 936, the clamping force can be precisely adjusted to ensure the stability and accuracy of the syringe 94 during the sampling process. Therefore, the application of the coupling 935 and the adjusting bracket 936 not only optimizes the structural design of the clamping assembly 93, but also improves the ease of use and operational accuracy of the entire injection device.

[0039] Please refer to Figure 7An adjusting handle 939 is fixedly installed at the bottom of the guide block 938. The guide block 938 has an elliptical shape when viewed from below. The outer side of the guide block 938 is fitted and connected to the inner side of the adjusting plate 937. When it is necessary to adjust the clamping state or position of the syringe 94, the operator can rotate the adjusting handle 939 to make the guide block 938 rotate at the bottom of the side rail 91, thereby adjusting the clamping force through a series of linkage mechanisms. In addition, the elliptical shape of the guide block 938 when viewed from below is not only aesthetically pleasing, but more importantly, it helps to increase the stability of the contact surface between the guide block 938 and the side rail 91, making it more stable during rotation and less prone to shaking. At the same time, the elliptical shape can also reduce the frictional resistance of the guide block 938 during rotation to a certain extent, making the operation smoother. Furthermore, the guide block... The outer side of 938 and the inner side of the adjusting plate 937 are tightly fitted together. This design ensures the stability and accuracy of the adjusting plate 937 during movement. When the adjusting plate 937 is subjected to external force, due to its tight fit with the guide block 938, it can ensure that the adjusting plate 937 moves along the shape of the guide block 938, preventing it from deviating from the predetermined trajectory. This connection method not only improves the overall structural stability of the clamping assembly 93, but also makes the position adjustment of the syringe 94 more accurate and reliable. The design of the guide block 938 fully considers the convenience, stability and accuracy of operation. Through design elements such as the adjusting handle 939, the elliptical upward-viewing shape and the tight fit with the adjusting plate 937, precise control of the clamping state of the syringe 94 is achieved, improving the practicality and operating experience of the injection device.

[0040] Please refer to Figure 6The limiting component 63 includes a fixed frame 631, which is fixedly installed on the outer side of the turntable 62 in a ring-shaped arrangement at equal intervals. Telescopic springs 632 are fixedly installed at both ends of the inner side of the fixed frame 631. Movable blocks 633 are fixedly installed at the inner ends of the telescopic springs 632. The movable blocks 633 are slidably connected to the inside of the fixed frame 631. Clamping seats 634 are fixedly installed at the inner ends of the movable blocks 633. Sample dishes 64 are inserted into the middle of the fixed frame 631 and located between the inner sides of the clamping seats 634. The fixed frame 631, as the basic structure of the limiting component 63, is fixedly installed on the outer side of the turntable 62 in a ring-shaped arrangement at equal intervals. This design not only ensures the uniformity of the distribution of the fixing brackets 631, but also allows the turntable 62 to rotate smoothly, reducing wobbling caused by uneven force. Both ends of the inner side of the fixing brackets 631 are fixedly installed with telescopic springs 632. These springs 632 have a certain degree of elasticity and restoring force; when subjected to external force, they can deform and quickly return to their original state after the force disappears. This characteristic allows the limiting component 63 to adaptively adjust according to the size and shape of the sample dish 64, ensuring the stability and reliability of the clamping. A movable block 63 is fixedly installed at the inner end of the telescopic spring 632. 3. The movable block 633 is slidably connected to the inside of the fixed frame 631. This design allows the movable block 633 to slide inside the fixed frame 631, thereby adjusting the position of the clamping seat 634 as needed. When it is necessary to place the sample dish 64, simply insert the sample dish 64 into the middle of the fixed frame 631 and position it between the inner sides of the clamping seat 634. At this time, the telescopic spring 632 will deform under the compression of the sample dish 64, causing the movable block 633 and the clamping seat 634 to move inward, thereby tightly clamping the sample dish 64. The clamping seat 634, as the part that directly contacts the sample dish 64, is also designed to fully utilize... Considering stability and compatibility, the inner shape and size of the clamping base 634 match the sample dish 64, ensuring that the sample dish 64 will not shake or slip during clamping. At the same time, the clamping base 634 is made of a soft material to reduce wear and contamination of the sample dish 64. The limiting component 63, through the synergistic action of the fixing frame 631, the telescopic spring 632, the movable block 633, and the clamping base 634, achieves stable clamping and adaptive adjustment of the sample dish 64. This design not only improves the reliability and safety of sample storage, but also simplifies the sample replacement and operation process, improving the efficiency and convenience of experimental work.

[0041] Please refer to Figure 5The sample storage mechanism 6 includes a third motor 61, which is fixedly installed at the bottom front end of the top seat 3. The output end of the third motor 61 passes through the top seat 3 and is fixedly installed on a turntable 62. Limiting components 63 are fixedly installed at equal intervals on the top of the turntable 62. A sample dish 64 is mounted on the top of the turntable 62 via the limiting components 63. The sample storage mechanism 6 mainly consists of the third motor 61, the turntable 62, and the limiting components 63. The third motor 61 is fixedly installed at the bottom front end of the top seat 3, serving as the power source for the entire storage mechanism. Its output end passes through the top seat 3 and is fixedly installed on the turntable 62. The turntable 62 is a key component for storing the sample dish 64. Limiting components 63 are fixedly installed at equal intervals on the top of the turntable 62. These limiting components 63 serve to fix and position the sample dish 64. Through the limiting components 63, the sample dish 64 can be stably placed on the turntable 62, preventing displacement or tipping during rotation or sampling. The third motor 61 drives the turntable 62 to rotate, causing the sample dish 64 to be sampled to rotate to the sampling position. At this time, the sampling mechanism 9 of the injection device, such as the previously mentioned syringe 94, will move above the sample dish 64 under a precise control system. The telescopic cylinder 5 pushes the syringe 94 downward, so that the needle of the syringe 94 is inserted into the sample dish 64, thereby completing the sampling operation. This design not only improves the accuracy and efficiency of sampling, but also greatly reduces the error and inconvenience of human operation. At the same time, through the cooperation of the turntable 62 and the limiting component 63, multiple sample dishes 64 can be continuously stored and sampled, further improving the continuity and automation of experimental work. The sample storage mechanism 6 is an important component of the liquid chromatography injection device. Through the coordinated work of the third motor 61, the turntable 62 and the limiting component 63, it realizes the stable storage and efficient sampling of samples, providing a reliable sample source for subsequent chromatographic analysis.

[0042] Please refer to Figure 5The top of the turntable 62 has evenly spaced receiving slots 635. The bottom of the sample dish 64 is inserted into the receiving slot 635. The receiving slots 635 are carefully designed according to the size and shape of the sample dish 64 to ensure that the sample dish 64 can be tightly inserted into the receiving slot 635. When the sample dish 64 is placed on the turntable 62, its bottom will naturally insert into the corresponding receiving slot 635, forming a stable support structure. The advantage of this design is that it can not only prevent the sample dish 64 from shifting or tipping over during the rotation of the turntable 62, but also reduce the sample... The friction between the sample dish 64 and the turntable 62 extends its service life. At the same time, the opening of the receiving groove 635 makes the placement of the sample dish 64 more neat and aesthetically pleasing, improving the visibility and operability of the entire sample storage mechanism 6. In addition, since the receiving groove 635 is equally spaced, it also ensures that the position of each sample dish 64 on the turntable 62 is uniformly distributed, avoiding problems such as uneven force or rotational imbalance caused by uneven position. This uniform distribution not only helps to improve the accuracy of the sampling process, but also helps to improve the stability and reliability of the entire sample introduction device.

[0043] Please refer to Figure 5 The inner side of the clamping seat 634 has a V-shaped design when viewed from above. The bottom of the turntable 62 is rotatably connected to ball bearings 636 arranged in a ring at equal intervals. The bottom of the ball bearings 636 is in close contact with the top of the top seat 3. Firstly, the V-shaped design allows the clamping seat 634 to generate an inward clamping force when squeezed by the sample dish 64. This clamping force is evenly distributed on the bottom of the sample dish 64, ensuring that the sample dish 64 does not shake or tilt during rotation or sampling. Secondly, the V-shaped clamping seat 634 can better adapt to sample dishes 64 of different sizes. Because the V-shaped opening has a certain width range, This design can accommodate sample dishes 64 of different diameters at the bottom, increasing the compatibility and flexibility of the clamping seat 634. This allows the sample storage mechanism 6 to be suitable for sample dishes 64 of various sizes. In addition, the bottom of the turntable 62 is rotatably connected with ball bearings 636 arranged in a ring at equal intervals. These ball bearings 636 not only reduce the friction between the turntable 62 and the top seat 3, making the turntable 62 rotate more smoothly, but also play a role in supporting and stabilizing the turntable 62. The bottom of the ball bearings 636 fits snugly against the top of the top seat 3, forming a stable support structure, ensuring the stability and balance of the turntable 62 when rotating at high speed.

[0044] The implementation principle of the liquid chromatography injection device in this embodiment is as follows: By setting up a sample storage mechanism 6, the sample dish 64 can be placed inside the receiving groove 635 on the top of the turntable 62 during use. At this time, the resetting of the extension spring 632 pushes the movable block 633 to slide inside the fixed frame 631. The elastic force of the extension spring 632 acts on the movable block 633 and the teeth of the fixed frame 631, which helps to clamp and fix the sample dish 64. It can be seen that during use, the device can flexibly adapt to sample dishes 64 of different sizes according to needs, which can improve the overall adaptability of the device. At the same time, during use, the third motor 61 can be started to drive the turntable 62 to rotate. The rotation of the turntable 62 drives the cyclic displacement of each culture dish on the top of the turntable 62, which can flexibly adjust the different sample dishes. The sample dish 64 is located at the bottom of the syringe 94. The sample dish 64 can be flexibly adjusted as needed. When it is necessary to inject a sample again after the injection is completed, the first motor 7 is started. The first motor 7 drives the fixed block 8 to rotate. By rotating the fixed block 8, the movement displacement of each syringe 94 on the outside of the fixed block 8 can be adjusted. Different syringes 94 can be selected as needed, which can avoid the situation of sharing a single syringe 94 for injection. This can improve the overall sample injection convenience of the device and also avoid the possibility of cross-contamination of samples, thus maximizing the overall detection accuracy. When it is necessary to replace the sample dish 64, since the telescopic spring 632 abuts against the movable block 633 to drive the clamping seat 634 for elastic clamping, the sample dish 64 can be pulled out. This allows for quick replacement of the sample dish 64 and improves the overall ease of use of the device.

[0045] By setting up the sampling mechanism 9, during sampling, when the sample dish 64 is moved to the bottom of the syringe 94 and the injection needle, the telescopic cylinder 5 is first activated to push the syringe 94 downward, and the needle of the syringe 94 is inserted into the sample dish 64. At this time, the second motor 921 is activated, which drives the lead screw 922 to rotate. The rotation of the lead screw 922 drives the sliding block 923 to slide inside the side rail 91. When the sliding block 923 slides upward, it assists in pulling the piston rod upward, and the syringe 94... Moving the piston rod upwards draws the sample into the syringe 94. At this point, starting the first motor 7 drives the fixed block 8 to rotate. The rotation of the fixed block 8 moves the syringe 94 to the injection tube 10. By starting the second motor 921, the lead screw 922 is driven to rotate in the reverse direction, which pushes the sliding block 923 to move the elastic mounting bracket 924 and the bracket 925 downwards. This pushes the piston rod downwards, and the downward movement of the piston rod pushes the drawn solution into the injection tube 10 outside the syringe 94, enabling the entire device to automatically inject samples.

[0046] By setting up the clamping assembly 93, when it is necessary to remove or install the syringe 94 inside the clamping assembly 93 during use, the adjusting handle 939 can be turned. Rotating the adjusting handle 939 will push the guide block 938 to move. As the guide block 938 rotates, its two ends will abut against the adjusting plate 937 and move outwards. The outward movement of the adjusting plate 937 will push the adjusting frame 936 to push the connecting shaft 935 outwards. The connecting shaft 935 will then pull the limiting block 933 to abut against the limiting spring 932 and retract. The movement of the limiting block 933 will cause the limiting frame 934 to separate, allowing the syringe 94 to be pulled out of the limiting frame 934. Pulling out the syringe 94 will activate the elastic locking frame 924, which is made of spring steel. The top of the piston rod of the syringe 94 can be stably engaged. The piston rod of the syringe 94 can be removed by adjusting the elastic locking bracket 924, allowing the entire syringe 94 to be disassembled. A new syringe 94 can then be taken out and inserted into the inner side of the limiting bracket 934. Loosening the adjusting handle 939 and resetting the limiting spring 932 will push the limiting block 933 inward. The limiting block 933 pushes the limiting bracket 934 inward, assisting in clamping and positioning the syringe 94. After the syringe 94 is clamped, the top of the piston rod can be engaged via the elastic locking mechanism, thus installing the syringe 94. This facilitates quick and easy disassembly and replacement of the syringe 94, improving the overall ease of use of the device and simplifying its operation.

[0047] The above are all preferred embodiments of this application, and are not intended to limit the scope of protection of this application. Therefore, all equivalent changes made in accordance with the structure, shape and principle of this application should be covered within the scope of protection of this application.

Claims

1. A liquid chromatography injection device, comprising a base (1), characterized in that: Support legs (2) are fixedly installed at the four corners of the top of the base (1). A top seat (3) is fixedly installed on the top of the support legs (2). A sample storage mechanism (6) is fixedly installed on the top of the top seat (3). A support frame (4) is fixedly installed on the rear side of the top of the top seat (3). A telescopic cylinder (5) is fixedly installed at the front end of the support frame (4). A first motor (7) is fixedly installed through the support frame (4) at the bottom output end of the telescopic cylinder (5). A fixing block (8) is fixedly installed at the bottom output end of the first motor (7). A sampling mechanism (9) is fixedly installed at equal intervals on the outer side of the fixing block (8). A sample inlet tube (10) is fixedly installed in the middle of the rear side of the top seat (3). The sampling mechanism (9) includes a side rail (91), which is fixedly installed at equal intervals on the outside of the fixed block (8). A displacement component (92) is movably installed inside the side rail (91). A clamping component (93) is fixedly installed at the lower outer end of the side rail (91). A syringe (94) is installed at the lower end of the side rail (91) through the clamping component (93). The clamping assembly (93) includes a fixed frame (931), which is fixedly installed at the lower end of the side rail (91). Limiting springs (932) are fixedly installed at both ends of the fixed frame (931). Limiting blocks (933) are fixedly installed at the ends of the limiting springs (932). Limiting frames (934) are fixedly installed on the outer sides of the limiting blocks (933). The syringe (94) is inserted between the inner sides of the limiting frames (934). A [missing information - likely a device or component] is fixedly installed at the outer end of the limiting blocks (933). A connecting shaft (935) is fixedly installed at its outer end through a fixed frame (931) with an adjusting bracket (936); an adjusting plate (937) is fixedly installed at the outer end of the adjusting bracket (936); a guide block (938) is rotatably connected to the bottom of the side rail (91); an adjusting handle (939) is fixedly installed at the bottom of the guide block (938); the guide block (938) has an elliptical shape when viewed from below; and the outer side of the guide block (938) and the inner side of the adjusting plate (937) are fitted together.

2. The liquid chromatography injection device according to claim 1, characterized in that: The displacement assembly (92) includes a second motor (921), which is fixedly installed on the top of the side rail (91). The bottom output end of the second motor (921) passes through the side rail (91) and is fixedly installed with a lead screw (922). The lead screw (922) is rotatably connected to the inside of the side rail (91). The outer surface of the lead screw (922) is threaded with a sliding block (923). An elastic clamping bracket (924) is fixedly installed on the outer side of the sliding block (923). A clamping bracket (925) is fixedly installed on the outer end of the elastic clamping bracket (924). The upper end of the piston rod of the syringe (94) is clamped inside the clamping bracket (925).

3. The liquid chromatography injection device according to claim 1, characterized in that: The sample storage mechanism (6) includes a third motor (61), which is fixedly installed at the bottom front end of the top seat (3). The output end of the third motor (61) passes through the top seat (3) and is fixedly installed with a turntable (62). Limiting components (63) are fixedly installed at equal intervals on the top of the turntable (62). A sample dish (64) is installed on the top of the turntable (62) through the limiting components (63).

4. The liquid chromatography injection device according to claim 3, characterized in that: The limiting component (63) includes a fixed frame (631), which is fixedly installed on the outside of the turntable (62) in a ring arrangement with equal spacing. Both ends of the inner side of the fixed frame (631) are fixedly installed with telescopic springs (632). The inner end of the telescopic springs (632) is fixedly installed with a movable block (633). The movable block (633) is slidably connected to the inside of the fixed frame (631). The inner end of the movable block (633) is fixedly installed with a clamping seat (634). The sample dish (64) is inserted into the middle of the fixed frame (631) and located between the inner sides of the clamping seat (634).

5. The liquid chromatography injection device according to claim 4, characterized in that: The top of the turntable (62) is provided with equal intervals of receiving grooves (635), and the bottom of the sample dish (64) is inserted into the inside of the receiving groove (635).

6. The liquid chromatography injection device according to claim 5, characterized in that: The inner side of the clamping seat (634) is V-shaped when viewed from above. The bottom of the turntable (62) is rotatably connected with balls (636) arranged in a ring at equal intervals. The bottom of the balls (636) and the top of the top seat (3) are fitted together.

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