A repairing composition containing a microcapsule of camellia japonica extract and application thereof

Abstract

The present application belongs to the technical field of cosmetics, and particularly relates to a repairing composition containing Camellia chrysantha extract microcapsules and application thereof. The present application provides a repairing composition containing Camellia chrysantha extract microcapsules, which comprises Camellia chrysantha extract microcapsules, hydrolyzed royal jelly protein, chamomile extract, European chestnut leaf extract and magnolia kobus extract, and synergistic effects of the five components can meet the purpose of barrier repair from multiple aspects such as physical barrier, immune barrier and microbial barrier, and the stability, safety and comprehensive efficacy of the composition are improved. The Camellia chrysantha extract microcapsules of the present application are wrapped with inulin as a wall material, which can enhance the thermal stability, effectively promote skin water absorption and moisture retention, relieve skin dryness and tightness and other problems, inhibit harmful bacteria and promote the growth of beneficial bacteria. The composition provided by the present application also has the advantages of simple preparation method, suitability for industrial production and the like, and can be applied to the preparation of repairing cosmetics, and has good market application value.

Description

Technical Field

[0001] This invention belongs to the field of cosmetic technology, specifically relating to a repair composition containing microcapsules of Camellia chrysantha extract and its application. Background Technology

[0002] The skin, located on the outermost layer of the human body, protects against external stimuli such as mechanical, physical, chemical, and bacterial microorganisms. The skin barrier is a structural barrier formed by the epidermal morphology cells of the stratum corneum and the lipids between the stratum corneum cells. It prevents excessive water loss from the body and prevents harmful substances such as chemicals or microorganisms from entering. Many mechanisms affect the skin barrier; abnormalities at different levels, including epidermal keratin differentiation, expression of intermediate keratin filament-related proteins, intercellular lipids in the stratum corneum, and the hydrolipidic film of the skin, can all affect skin barrier function.

[0003] With increasing environmental pollution, rising life pressures, and factors such as improper use of cosmetics and excessive cosmetic procedures, the skin barrier is damaged. Once the barrier is damaged, the skin's ability to retain moisture and its defense functions decline, often manifesting as dryness and sensitivity. This can easily trigger or worsen conditions such as atopic dermatitis, eczema, psoriasis, ichthyosis, irritant dermatitis, and steroid-induced dermatitis. Simultaneously, an imbalance in sebum secretion leads to oily skin, causing seborrheic disorders such as acne, rosacea, and seborrheic dermatitis. When the skin barrier is severely damaged, its own balancing and repair mechanisms are often insufficient for self-repair.

[0004] Existing barrier repair products often have limited efficacy, primarily focusing on hydration and moisturizing without providing genuine repair. Others use plant extracts as active ingredients, but their specific effects are unclear, resulting in poor repair outcomes. Repairing the skin barrier is currently a challenging and crucial research area; therefore, developing a repair composition to meet the needs of the current cosmetics market is essential. Summary of the Invention

[0005] In view of the above-mentioned defects or improvement needs of the prior art, the present invention provides a repair composition containing camellia extract microcapsules and its application, as well as an aftershave product prepared using the soothing repair composition, so as to solve the problems of poor effect and single function of existing repair products.

[0006] The objective of this invention can be achieved through the following technical solutions:

[0007] In a first aspect, the present invention provides a repair composition containing Camellia chrysantha extract microcapsules, the composition comprising, by weight, the following components: 0.1-0.3 parts Camellia chrysantha extract microcapsules, 0.1-0.3 parts hydrolyzed royal jelly protein, 0.08-0.15 parts chamomile extract, 1.5-2.5 parts European chestnut leaf extract, and 1.5-2.5 parts Magnolia sieboldii extract.

[0008] Golden camellia extract is rich in active ingredients such as polyphenols, flavonoids, and saponins, exhibiting excellent antioxidant, anti-inflammatory, and photodamage repair effects. It can also promote the production of skin barrier proteins, thus repairing the skin barrier. However, the active ingredients, such as tea polyphenols, are easily degraded by heat, preventing them from fully exerting their effects. Existing technologies use polymers as carriers to encapsulate them to improve stability, but this raises concerns about safety and complex processes. Inulin is a plant oligosaccharide that can bind with free water, increasing the water content of the stratum corneum. Furthermore, it has inhibitory effects on bacteria such as Escherichia coli, Bacillus subtilis, and Staphylococcus aureus, effectively maintaining the skin's microecological balance. The golden camellia extract microcapsules of this invention use inulin as the wall material to encapsulate the golden camellia flower extract, enhancing thermal stability, effectively promoting skin hydration, and alleviating dryness and tightness.

[0009] Hydrolyzed royal jelly protein can promote collagen production, prevent wrinkles and loss of elasticity in the skin, and also promote the production of ceramides.

[0010] Chamomile extract contains bisabolol and apigenin, which can directly inhibit the NF-κB pathway, reducing the release of inflammatory factors such as IL-6 and TNF-α; it can also activate the EGF receptor signaling pathway, promoting keratinocyte migration and differentiation. Its core effects are the anti-inflammatory and soothing effects of bisabolol and the epidermal regeneration-promoting and wound-healing effects of apigenin.

[0011] Astragaloside and quercetin-3-O-glucuronide in chestnut leaf extract can inhibit the activity of lipase produced by Staphylococcus aureus, reducing the favorable environment for Staphylococcus aureus invasion and thus inhibiting the excessive proliferation of Staphylococcus aureus.

[0012] Magnolia officinalis extract contains rich moisturizing ingredients that can increase the skin's moisture content, enhance its water retention capacity, and keep the skin hydrated.

[0013] Preferably, the composition comprises the following components by weight: 0.2 parts of Camellia chrysantha extract microcapsules, 0.2 parts of hydrolyzed royal jelly protein, 0.1 parts of chamomile extract, 2 parts of chestnut leaf extract, and 2 parts of Magnolia officinalis extract.

[0014] Preferably, the preparation method of the Camellia chrysantha extract microcapsules includes the following steps:

[0015] S1. Preparation of Camellia chrysanthemi extract;

[0016] S2. Preparation of Camellia chrysantha extract microcapsules.

[0017] More preferably, step S1 specifically includes: taking fresh Camellia chrysantha, drying it to constant weight at 50-60℃, pulverizing it, and passing it through a 30-40 mesh sieve to obtain Camellia chrysantha powder; taking the Camellia chrysantha powder, adding it to an ethanol solution with a volume concentration of 50-60% at a material-to-liquid ratio of 1g:(30-40)mL, mixing it evenly, and extracting it with ultrasound assistance at room temperature and 250-300W for 60-80min, filtering it, taking the filtrate, and rotary evaporating it at 40-60℃ until there is no alcohol odor to obtain Camellia chrysantha extract.

[0018] More preferably, step S2 specifically includes: taking inulin, adding deionized water, and preparing a mixed solution with a mass concentration of 20-30%; mixing the mixed solution with the Camellia chrysantha extract prepared in step S1 at a ratio of 1 mL: (1.5-2.5 mL), pre-freezing at -15℃ to -20℃ for 18-24 h, and then freeze-drying at 5-10 Pa and -50℃ to -65℃ for 66-78 h to obtain the Camellia chrysantha extract microcapsules.

[0019] The second aspect of the present invention is to provide a method for preparing the repair composition described in the first aspect of the present invention, comprising the following steps: taking Camellia chrysantha extract microcapsules, dissolving them in 9-11 times their volume of water, hydrating them at room temperature for 22-26 hours, adding the remaining components, mixing and stirring until homogeneous, to obtain the repair composition.

[0020] The third aspect of this invention aims to provide the application of the repair composition described in the first aspect of this invention or the repair composition prepared by the preparation method described in the second aspect of this invention in the preparation of repair cosmetics, wherein the cosmetics are toners, lotions, creams, masks, serums or sprays, and the amount of the composition added is 2%-8% of the total weight of the cosmetics.

[0021] A third aspect of this invention aims to provide an emulsion comprising the following ingredients by weight percentage: 2-8% of the repair composition described in the first aspect or the repair composition prepared by the method described in the second aspect, 3%-5% glycerin, 0.1%-0.3% carbomer 980, 3-5% caprylic / capric triglyceride, 1.5-2.5% C14-22 alkyl alcohol / C12-20 alkyl glucoside, 1.5-2.5% polydimethylsiloxane, 0.3-0.8% cetearyl alcohol, 0.3-0.8% 1,2-hexanediol, 0.3-0.8% p-hydroxyacetophenone, 1.5-2.5% 1,3-propanediol, 0.1%-0.3% arginine, and the balance being deionized water.

[0022] Preferably, the emulsion comprises the following raw materials in weight percentage: 5% of the repair composition described in the first aspect or the repair composition prepared by the method described in the second aspect, 4% glycerin, 0.15% carbomer 980, 4% caprylic / capric triglyceride, 2% C14-22 alkyl alcohol / C12-20 alkyl glucoside, 2% polydimethylsiloxane, 0.5% cetearyl alcohol, 0.5% 1,2-hexanediol, 0.5% p-hydroxyacetophenone, 2% 1,3-propanediol, 0.15% arginine, and the balance being deionized water.

[0023] A fourth aspect of this invention aims to provide a method for preparing an emulsion comprising the emulsion described in the third aspect, comprising the following steps:

[0024] A1. Mix glycerin, carbomer 980 and deionized water, heat to 80°C, and homogenize at 1200 rpm for 5 minutes. After homogenization, keep warm for later use to obtain the aqueous phase.

[0025] A2. Mix caprylic / capric triglyceride, C14-22 alkyl alcohol / C12-20 alkyl glucoside, polydimethylsiloxane, and cetearyl alcohol. Heat to 80°C and homogenize at 1200 rpm for 5 minutes. After homogenization, keep warm for later use to obtain the oil phase.

[0026] A3. Mix 1,2-hexanediol, p-hydroxyacetophenone, and 1,3-propanediol, and heat to 60°C to melt, to obtain a preservative;

[0027] A4. Heat the aqueous phase to 80°C, add the oil phase at 300 rpm, stir and mix. Then cool down to 60°C, add the preservative at 300 rpm and stir and mix. Then cool down to 45°C, add the repair composition and continue stirring for 5 minutes. Finally, add arginine to adjust the pH, then stop stirring and discharge to obtain the emulsion.

[0028] The beneficial effects of this invention are:

[0029] This invention provides a repair composition containing microcapsules of Camellia chrysantha extract. The composition comprises Camellia chrysantha extract microcapsules, hydrolyzed royal jelly protein, chamomile extract, chestnut leaf extract, and Magnolia officinalis extract. These five ingredients work synergistically to address multiple barriers, including physical, immune, and microbial barriers, enhancing the composition's stability, safety, and overall efficacy. The Camellia chrysantha extract microcapsules of this invention use inulin as the wall material to encapsulate the Camellia chrysantha flower extract, which enhances thermal stability, effectively promotes skin hydration, and alleviates dryness and tightness. Simultaneously, inulin, as a prebiotic, selectively inhibits harmful bacteria (such as Escherichia coli and Staphylococcus aureus) and promotes the growth of beneficial bacteria. Synergistically with chestnut leaf extract, it inhibits the excessive proliferation of harmful bacteria by both suppressing their growth and reducing environments conducive to their growth. This addresses the issue that existing skin repair products often focus on repairing the physical barrier, such as supplementing lipids or moisturizing ingredients, while neglecting the synergistic regulation of the microbial and immune barriers, resulting in incomplete repair. The composition provided by this invention also has the advantages of simple preparation method and suitability for industrial production. It can be applied to the preparation of repair cosmetics and has good market application value. Detailed Implementation

[0030] To further illustrate the technical means and effects of the present invention in achieving its intended purpose, the following detailed description of the specific implementation methods, structures, features and effects of the present invention, in conjunction with embodiments, is provided below.

[0031] Unless otherwise specified, experimental methods in the following examples are generally performed under standard conditions or as recommended by the manufacturer. All materials and reagents used are commercially available unless otherwise specified.

[0032] The golden camellia was purchased from Guangdong Fudonghai Pharmaceutical Co., Ltd., and its product name is golden camellia.

[0033] Hydrolyzed royal jelly protein was purchased from Katakura & Co-op Agri Co., Ltd. in Japan, under the trade name ROYALBIOCYTE;

[0034] Chamomile extract was purchased from Xi'an Hengji Chemical Co., Ltd., and its trade name is Chamomile Extract.

[0035] European chestnut leaf extract was purchased from BASF under the brand name Castaline®.

[0036] Magnolia officinalis extract was purchased from Guangzhou Jinbaolai Biotechnology Co., Ltd., and its trade name is Magnolia officinalis extract.

[0037] Golden Camellia Extract

[0038] Its preparation method includes the following steps:

[0039] Fresh Camellia chrysantha was dried to constant weight at 55℃, pulverized, and passed through a 40-mesh sieve to obtain Camellia chrysantha powder. The Camellia chrysantha powder was added to a 55% ethanol solution at a material-to-liquid ratio of 1g:35mL, mixed evenly, and extracted with ultrasound at room temperature and 300W for 70min. The mixture was filtered, and the filtrate was rotary evaporated at 50℃ until no alcohol odor was detected to obtain Camellia chrysantha extract.

[0040] Golden Camellia Extract Microcapsules

[0041] Its preparation method includes the following steps:

[0042] S1. Take fresh Camellia chrysantha, dry it at 55℃ to constant weight, pulverize it, and pass it through a 40-mesh sieve to obtain Camellia chrysantha powder; take the Camellia chrysantha powder, add 55% ethanol solution at a material-to-liquid ratio of 1g:35mL, mix well, and extract with ultrasonic assistance at room temperature and 300W for 70min. Filter, take the filtrate, and rotary evaporate it at 50℃ until there is no alcohol smell to obtain Camellia chrysantha extract.

[0043] S2. Take inulin, add deionized water, and prepare a mixed solution with a mass concentration of 25%; mix the mixed solution with the golden camellia extract prepared in step S1 at a ratio of 1 mL: 2 mL, pre-freeze at -18℃ for 24 h, and then freeze-dry at 5 Pa and -60℃ for 72 h to obtain the golden camellia extract microcapsules.

[0044] The component composition (parts by weight) of the repair compositions 1-3 in this invention is shown in Table 1 below. The preparation method of the repair compositions includes the following steps: take the Camellia chrysantha extract microcapsules, add 10 times the volume of water to dissolve them, hydrate them at room temperature for 24 hours, add other components in the composition, mix and stir until completely dissolved to obtain each repair composition.

[0045] Table 1. Components and weight parts of repair compositions 1-3

[0046] Composition Golden Camellia Extract Microcapsules (parts by weight) Hydrolyzed royal jelly protein (parts by weight) Chamomile extract (parts by weight) European chestnut leaf extract (parts by weight) Magnolia officinalis extract (parts by weight) 1 0.2 0.2 0.1 2 2 2 0.1 0.1 0.08 1.5 1.5 3 0.3 0.3 0.15 2.5 2.5

[0047] Composition 4

[0048] The difference between Composition 4 and Composition 1 is that Composition 4 does not contain Camellia chrysantha extract microcapsules as active ingredients, and uses hydrolyzed royal jelly protein, chamomile extract, European chestnut leaf extract and Magnolia officinalis extract in a weight ratio of 0.2:0.1:2:2 to make up for the missing amount.

[0049] Composition 5

[0050] The difference between composition 5 and composition 1 is that the active ingredient in composition 5 does not contain hydrolyzed royal jelly protein, and the missing amount is made up by using Camellia chrysantha extract microcapsules, chamomile extract, chestnut leaf extract and Magnolia officinalis extract in a weight ratio of 0.2:0.1:2:2.

[0051] Composition 6

[0052] The difference between composition 6 and composition 1 is that the active ingredient in composition 6 does not contain chamomile extract, and the missing amount is made up by using Camellia chrysantha extract microcapsules, hydrolyzed royal jelly protein, European chestnut leaf extract and Magnolia officinalis extract in a weight ratio of 0.2:0.2:2:2.

[0053] Composition 7

[0054] The difference between composition 7 and composition 1 is that the active ingredient in composition 7 does not contain European chestnut leaf extract, and the missing amount is made up by using Camellia chrysantha extract microcapsules, hydrolyzed royal jelly protein, chamomile extract and Magnolia officinalis extract in a weight ratio of 0.2:0.2:0.1:2.

[0055] Composition 8

[0056] The difference between composition 8 and composition 1 is that the active ingredient in composition 8 does not contain Magnolia officinalis extract, and the missing amount is made up by Camellia chrysantha extract microcapsules, hydrolyzed royal jelly protein, chamomile extract and chestnut leaf extract in a weight ratio of 0.2:0.2:0.1:2.

[0057] Composition 9

[0058] The difference between composition 9 and composition 1 is that the total weight of the composition remains the same, and the weight ratio of Camellia chrysantha extract microcapsules, hydrolyzed royal jelly protein, chamomile extract, chestnut leaf extract and Magnolia officinalis extract is 2:0.2:0.1:0.2:2.

[0059] Composition 10

[0060] The difference between composition 10 and composition 1 is that the total weight of the composition remains unchanged, and the weight ratio of Camellia chrysantha extract microcapsules, hydrolyzed royal jelly protein, chamomile extract, chestnut leaf extract and Magnolia officinalis extract is 0.2:2:0.1:2:0.2.

[0061] The preparation method of repair compositions 7-10 is the same as that of repair compositions 1-3.

[0062] Test Example 1: Thermal stability test of Camellia chrysantha extract microcapsules

[0063] Samples to be tested: The Camellia chrysantha extract and Camellia chrysantha extract microcapsules prepared in this invention were taken in portions and stirred in a water bath at 90°C for 6 hours, and collected. PBS buffer was added to the untreated and heat-treated Camellia chrysantha extracts and Camellia chrysantha extract microcapsules to prepare test solutions with a mass concentration of 10%.

[0064] The specific experimental procedure is as follows:

[0065] (1) Dissolve 0.001972g of DPPH in anhydrous ethanol solution, and make up to 25mL with anhydrous ethanol solution to obtain DPPH test solution;

[0066] (2) After preparing the solutions in tubes A, B and C as follows, all tubes were placed at room temperature and in the dark for 30 minutes. The absorbance was measured at 517 nm and the absorbance value was recorded. Each sample was measured three times. The data were presented as the average value. The test was zeroed using anhydrous ethanol solution.

[0067] Tube A: 2 mL of the solution to be tested + 2 mL of DPPH test solution;

[0068] Tube B: 2 mL DPPH test solution + 2 mL PBS;

[0069] Tube C: 2 mL PBS + 2 mL test solution;

[0070] Calculate the DPPH free radical scavenging rate using the following formula:

[0071] DPPH free radical scavenging rate = 1 - (AC) / B × 100%;

[0072] In the formula: A is the absorbance value of tube A, B is the absorbance value of tube B, and C is the absorbance value of tube C;

[0073] The calculated data are shown in Table 2 below;

[0074] Table 2 DPPH free radical scavenging rate data

[0075]

[0076] As shown in Table 2, the DPPH radical scavenging rates of Camellia chrysantha extract and Camellia chrysantha extract microcapsules were almost equal. However, the DPPH radical scavenging rate of Camellia chrysantha extract decreased significantly after heat treatment. Although the DPPH radical scavenging rate of Camellia chrysantha extract microcapsules also decreased significantly after heat treatment, it was still significantly higher than that of the Camellia chrysantha extract group. This indicates that the Camellia chrysantha extract microcapsules prepared by inulin encapsulation have excellent thermal stability compared to Camellia chrysantha extract.

[0077] Test Example 2: Soothing Efficacy Test

[0078] filaggrin (FLG) is an important molecule in the stratum corneum of human skin that connects keratin fibers. With the assistance of FLG monomers, keratin fibers aggregate regularly, forming a solid physical barrier on the outermost layer of the epidermis, which strengthens the skin.

[0079] The cell line used was human keratinocytes (HaCaT, Beina Biotechnology). The testing conditions were: incubator temperature 37±1℃, humidity 90±5%, carbon dioxide 5±1%. Cells were cultured and treated according to groups, followed by testing. Specifically, the filaggrin (FLG) content was detected using the following method:

[0080] (1) The cell suspension was seeded into a 96-well cell culture plate at a density of 2000 cells / well. 100 μL of DMEM medium (2105341, Gibco) was added to each well and cultured for 24 h.

[0081] (2) Discard the supernatant, add 100 μL of PBS buffer to each well, and expose to UVB irradiation at a dose of 80 mJ / cm². 2 ;

[0082] (3) After irradiation, the supernatant was discarded. 100 μL of DMEM medium was added to the control group and 100 μL of DMEM medium containing 0.1 wt% of the corresponding samples (compositions 1-10) was added to the sample group. Each group was set up with 6 wells for parallel replication and cultured for 24 h.

[0083] (4) Collect cells from each group, discard the supernatant, lyse the cells with RIPA lysis buffer containing protease inhibitor (Shanghai Merck, V900854), centrifuge the lysed sample at 12000g for 5 minutes, and take the supernatant for subsequent experiments.

[0084] (5) Detection of filaggrin (FLG) content: The filaggrin (FLG) content of the supernatant of each group was detected using a human filaggrin (FLG) ELISA kit (catalog number BLL107115E, Baililai Biotechnology). The specific operation was as follows: equal amounts of supernatant were added to the corresponding reaction wells of the kit. After incubation, washing, and color development, the absorbance (OD) value was measured at a specific wavelength using an ELISA reader. The filaggrin (FLG) content of each group was calculated according to the standard curve. The skin barrier repair ability of the composition was represented by the improvement of filaggrin (FLG) content, as shown in the following formula:

[0085] FLG improvement rate = (FLG content) 样品组 / FLG content 对照组 -1) × 100%;

[0086] The results are shown in Table 3:

[0087] Table 3 Data on FLG growth rate

[0088] Group FLG increase rate (%) Composition 1 45.08 Composition 2 42.79 Composition 3 44.13 Composition 4 25.82 Composition 5 30.78 Composition 6 31.25 Composition 7 29.67 Composition 8 27.19 Composition 9 37.46 Composition 10 39.02

[0089] As shown in Table 3, compared with composition 1, the FLG increase rate of compositions 4-10 all decreased significantly, indicating that the five components of Camellia chrysantha extract microcapsules, hydrolyzed royal jelly protein, chamomile extract, European chestnut leaf extract and Magnolia officinalis extract work synergistically to improve the barrier repair effect of the composition.

[0090] Combining the data from compositions 1-3 and 9-10 in Table 3, it can be seen that the FLG increase rate of compositions 9-10 is significantly lower than that of composition 1. This indicates that the ratio of Camellia chrysantha extract microcapsules, hydrolyzed royal jelly protein, chamomile extract, chestnut leaf extract, and Magnolia officinalis extract affects the repair efficacy of the compositions. When the weight parts are in the range of (0.1-0.3):(0.08-0.15):(1.5-2.5):(1.5-2.5), the composition has a better barrier repair effect, and when the weight parts are 0.2:0.2:0.1:2:2, the composition has the best barrier repair effect.

[0091] Application example: Emulsion preparation

[0092] Compositions 1-10 were added to the emulsion at a concentration of 5 wt% to obtain the emulsions of application examples 1-10.

[0093] The method for preparing the emulsions using Examples 1-10 specifically includes the following steps:

[0094] The emulsion described in this application example comprises the following ingredients by weight percentage: 5% repair composition, 4% glycerin, 0.15% carbomer 980, 4% caprylic / capric triglyceride, 2% C14-22 alkyl alcohol / C12-20 alkyl glucoside, 2% polydimethylsiloxane, 0.5% cetearyl alcohol, 0.5% 1,2-hexanediol, 0.5% p-hydroxyacetophenone, 2% 1,3-propanediol, 0.15% arginine, and the balance being deionized water.

[0095] The method for preparing an emulsion includes the following steps:

[0096] A1. Mix glycerin, carbomer 980 and deionized water, heat to 80°C, and homogenize at 1200 rpm for 5 minutes. After homogenization, keep warm for later use to obtain the aqueous phase.

[0097] A2. Mix caprylic / capric triglyceride, C14-22 alkyl alcohol / C12-20 alkyl glucoside, polydimethylsiloxane, and cetearyl alcohol. Heat to 80°C and homogenize at 1200 rpm for 5 minutes. After homogenization, keep warm for later use to obtain the oil phase.

[0098] A3. Mix 1,2-hexanediol, p-hydroxyacetophenone, and 1,3-propanediol, and heat to 60°C to melt, to obtain a preservative;

[0099] A4. Heat the aqueous phase to 80°C, add the oil phase at 300 rpm, stir and mix. Then cool down to 60°C, add the preservative at 300 rpm and stir and mix. Then cool down to 45°C, add the repair composition and continue stirring for 5 minutes. Finally, add arginine to adjust the pH, then stop stirring and discharge to obtain the emulsion.

[0100] Test Example 3: Skin Barrier Repair and Moisturizing Effect Test

[0101] Several volunteers aged 18-45 were selected. On the day of the test, no skincare products were applied. After cleansing their faces, the subjects sat quietly for 30 minutes in a constant temperature and humidity room at 21±1℃ and 50±10%. The initial TEWL (Transdermal Water Loss) value and moisture content of the subjects were measured using a Tewameter®™ Hex (Courage+Khazaka) transdermal water loss probe and a Corneometer® CM 825 (Courage+Khazaka) moisture probe. The subjects were randomly divided into 10 groups of 6 people each. They were randomly assigned to use the lotion described in this invention example, applied once daily in the morning at a dosage of 1g. On days 14 and 28, the indicators were tested in the morning, and the improvement in TEWL value and moisture content was analyzed. The average data was taken. The improvement rate was calculated using the following formula:

[0102] ;

[0103] In the formula:

[0104] X 使用前 Data on various indicators tested before subjects used the product;

[0105] X 使用后 Data on various indicators tested before subjects used the product;

[0106] Table 4 Results of the product efficacy test after 14 days of use.

[0107] Group Moisture improvement rate (%) TEWL value improvement rate (%) Application Example 1 30.78 14.02 Application Example 2 27.69 12.96 Application Example 3 29.01 13.40 Application Example 4 12.79 6.17 Application Example 5 16.58 9.21 Application Example 6 14.88 7.64 Application Example 7 15.07 8.79 Application Example 8 13.76 6.82 Application Example 9 25.18 11.82 Application Example 10 24.73 10.67

[0108] Table 5 Results of product efficacy test after 28 days of use.

[0109] Group Moisture improvement rate (%) TEWL value improvement rate (%) Application Example 1 45.82 20.17 Application Example 2 41.96 18.34 Application Example 3 43.24 19.86 Application Example 4 21.39 9.82 Application Example 5 25.76 13.04 Application Example 6 24.08 11.87 Application Example 7 23.97 12.56 Application Example 8 22.95 10.23 Application Example 9 38.99 17.87 Application Example 10 37.14 16.95

[0110] As shown in Table 4-5, compared with Application Example 1, the moisture improvement rate and TEWL value improvement rate of Application Examples 4-10 were significantly reduced, indicating that the five components of Camellia chrysantha extract microcapsules, hydrolyzed royal jelly protein, chamomile extract, European chestnut leaf extract and Magnolia officinalis extract work synergistically to improve the barrier repair effect of the emulsion.

[0111] As shown in Tables 4-5, Application Examples 1-3 and 9-10, compared with Application Example 1, the moisture improvement rate and TEWL value improvement rate of Application Examples 9-10 were significantly reduced. This indicates that the ratio of Camellia chrysantha extract microcapsules, hydrolyzed royal jelly protein, chamomile extract, chestnut leaf extract, and Magnolia officinalis extract affects the barrier repair efficacy of the emulsion. When the weight ratio is in the range of (0.1-0.3):(0.08-0.15):(1.5-2.5):(1.5-2.5), the prepared emulsion has a better barrier repair effect. When the weight ratio is 0.2:0.2:0.1:2:2, the prepared emulsion has the best barrier repair effect.

[0112] Combining the data from Tables 4 and 5 after 14 and 28 days of emulsion use, respectively, it can be seen that the moisture improvement rate and TEWL value improvement rate of the emulsions prepared in Examples 1-10 both increased significantly, indicating that the emulsions have better soothing and repairing effects on the skin as the usage time increases.

[0113] The above description is merely a preferred embodiment of the present invention and is not intended to limit the present invention in any way. Although the present invention has been disclosed above with reference to preferred embodiments, it is not intended to limit the present invention. Any person skilled in the art can make some modifications or alterations to the above-disclosed technical content to create equivalent embodiments without departing from the scope of the present invention. Any simple modifications, equivalent changes and alterations made to the above embodiments based on the technical essence of the present invention without departing from the scope of the present invention shall still fall within the scope of the present invention.

Claims

1. A repair composition containing microcapsules of Camellia chrysantha extract, characterized in that, The composition comprises, by weight, the following components: 0.1-0.3 parts of Camellia chrysantha extract microcapsules, 0.1-0.3 parts of hydrolyzed royal jelly protein, 0.08-0.15 parts of chamomile extract, 1.5-2.5 parts of chestnut leaf extract, and 1.5-2.5 parts of Magnolia sieboldii extract; The preparation method of the Camellia chrysanthemi extract microcapsules includes the following steps: S1. Preparation of Camellia chrysantha extract: Take fresh Camellia chrysantha, dry it to constant weight at 50-60℃, pulverize it, and pass it through a 30-40 mesh sieve to obtain Camellia chrysantha powder; take the Camellia chrysantha powder, add it to an ethanol solution with a volume concentration of 50-60% at a material-to-liquid ratio of 1g:(30-40)mL, mix well, and extract with ultrasonic assistance at room temperature and 250-300W for 60-80min. Filter, take the filtrate, and rotary evaporate it at 40-60℃ until there is no alcohol odor to obtain Camellia chrysantha extract; S2. Preparation of Camellia chrysantha extract microcapsules: Take inulin, add deionized water, and prepare a mixed solution with a mass concentration of 20-30%; mix the mixed solution with the Camellia chrysantha extract prepared in step S1 at a ratio of 1 mL: (1.5-2.5) mL, pre-freeze at -15℃ to -20℃ for 18-24 h, and then freeze-dry at 5-10 Pa and -50℃ to -65℃ for 66-78 h to obtain the Camellia chrysantha extract microcapsules.

2. The repair composition as claimed in claim 1, characterized in that, The composition comprises, by weight, the following components: 0.2 parts of Camellia chrysantha extract microcapsules, 0.2 parts of hydrolyzed royal jelly protein, 0.1 parts of chamomile extract, 2 parts of chestnut leaf extract, and 2 parts of Magnolia officinalis extract.

3. The method for preparing the repair composition as described in claim 1 or 2, characterized in that, Includes the following steps: Take the Camellia chrysantha extract microcapsules, add 9-11 times the volume of water to dissolve them, and hydrate them at room temperature for 22-26 hours. Then add the remaining components, mix and stir evenly to obtain the repair composition.

4. The use of the repair composition as described in claim 1 or 2, or the repair composition prepared by the preparation method as described in claim 3, in the preparation of repair cosmetics, characterized in that, The cosmetic is a toner, lotion, cream, mask, serum, or spray, and the amount of the composition added is 2%-8% of the total weight of the cosmetic.

5. An emulsion, characterized in that, The product comprises the following ingredients by weight percentage: 2-8% of the repair composition as described in claim 1 or 2 or the repair composition prepared by the method described in claim 3, 3%-5% glycerin, 0.1%-0.3% carbomer 980, 3-5% caprylic / capric triglyceride, 1.5-2.5% C14-22 alkyl alcohol / C12-20 alkyl glucoside, 1.5-2.5% polydimethylsiloxane, 0.3-0.8% cetearyl alcohol, 0.3-0.8% 1,2-hexanediol, 0.3-0.8% p-hydroxyacetophenone, 1.5-2.5% 1,3-propanediol, 0.1%-0.3% arginine, and the balance being deionized water.

6. The emulsion as described in claim 5, characterized in that, The raw materials include the following weight percentages: 5% of the repair composition as described in claim 1 or 2 or the repair composition prepared by the method described in claim 3, 4% glycerin, 0.15% carbomer 980, 4% caprylic / capric triglyceride, 2% C14-22 alkyl alcohol / C12-20 alkyl glucoside, 2% polydimethylsiloxane, 0.5% cetearyl alcohol, 0.5% 1,2-hexanediol, 0.5% p-hydroxyacetophenone, 2% 1,3-propanediol, 0.15% arginine, and deionized water as the balance.

7. The method for preparing the emulsion as described in claim 5 or 6, characterized in that, Includes the following steps: A1. Mix glycerin, carbomer 980 and deionized water, heat to 80°C, and homogenize at 1200 rpm for 5 minutes. After homogenization, keep warm for later use to obtain the aqueous phase. A2. Mix caprylic / capric triglyceride, C14-22 alkyl alcohol / C12-20 alkyl glucoside, polydimethylsiloxane, and cetearyl alcohol. Heat to 80°C and homogenize at 1200 rpm for 5 minutes. After homogenization, keep warm for later use to obtain the oil phase. A3. Mix 1,2-hexanediol, p-hydroxyacetophenone, and 1,3-propanediol, and heat to 60°C to melt, to obtain a preservative; A4. Heat the aqueous phase to 80°C, add the oil phase at 300 rpm, stir and mix. Then cool down to 60°C, add the preservative at 300 rpm and stir and mix. Then cool down to 45°C, add the repair composition and continue stirring for 5 minutes. Finally, add arginine to adjust the pH, then stop stirring and discharge to obtain the emulsion.

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