粪肠球菌SZ07在制备抗卵形鲳鲹神经坏死病毒鱼饲料、药物上的应用

By using Enterococcus faecalis SZ07 to regulate the immune response and gut microbiota of oval pomfret, combined with multi-omics screening and optimized aquaculture management, the problem of resistance to neuronecrosis virus in oval pomfret was solved, the fish's disease resistance and growth performance were improved, and the sustainable development of the aquaculture industry was promoted.

CN120959328BActive Publication Date: 2026-07-17SHENZHEN INST OF GUANGDONG OCEAN UNIV +2

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
SHENZHEN INST OF GUANGDONG OCEAN UNIV
Filing Date
2025-07-02
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

Existing technologies are insufficient to effectively control the nerve necrosis virus in oval pomfret. Traditional vaccines have unstable immunization effects, the application of probiotics lacks in-depth research, feeds lack targeted enhancement of fish immunity, and aquaculture management does not fully consider the balance of the microbial community, resulting in weak antiviral capabilities.

Method used

Enterococcus faecalis SZ07 was used as a probiotic to improve the immune and antioxidant capacity of fish by regulating their immune response. Combined with specific aquaculture conditions, feed and water quality management were optimized to screen probiotics with strong stress resistance and outstanding adhesion ability, and a multi-omics technology screening system was established.

Benefits of technology

It significantly improves the antiviral ability of oval pomfret, enhances growth performance and quality, increases seedling survival rate, and promotes the healthy development of the aquaculture industry.

✦ Generated by Eureka AI based on patent content.

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Abstract

本发明提供一种粪肠球菌SZ07在制备抗卵形鲳鲹神经坏死病毒鱼饲料上的应用,粪肠球菌SZ07的保藏编号为GDMCC No:66159,保藏中心为广东省微生物菌种保藏中心。经相关实验证明,本发明所提供的粪肠球菌SZ07,其能够有效改善卵形鲳鲹的肠道形态,并且更重要的是,能够有效调节卵形鲳鲹鱼体免疫应答,提高卵形鲳鲹免疫能力、抗氧化能力等,因而有效提高了卵形鲳鲹的抗病毒能力,特别是明显提高了卵形鲳鲹的抗神经坏死病毒能力。即本发明的所提供的粪肠球菌SZ07能够有效防控卵形鲳鲹的病毒性神经坏死病,提高卵形鲳鲹苗种的成活率、生长速度和抗病能力,推动卵形鲳鲹养殖产业的健康发展。
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