Portable digestive tract tumor puncture and efficient sampling linkage device

Abstract

The invention discloses a convenient digestive tract tumor puncture and efficient sampling linkage device in the field of oncology diagnosis and treatment equipment, which comprises a handle, a sampling assembly is detachably connected to the handle, a puncture assembly is arranged at the tail end, away from the handle, of the sampling assembly, a supporting assembly is fixedly connected to the periphery of the sampling assembly, and a controller is arranged in the handle. The supporting assembly is in signal connection with the controller. The device is novel and effective, the sampling assembly achieves synchronous sampling at different depths by nesting a needle tube and a sampling tube, the puncture assembly achieves stable deformation of a puncture needle head by means of a puncture piece, a conical lantern ring and the like, the tedious steps of replacing the puncture needle are reduced, and the supporting assembly supports surrounding tissue through expansion of an expansion rod, a pressure sensor and the like; space and view are provided for puncture sampling, and the effects of convenient operation and rapid sampling are achieved.

Description

Technical Field

[0001] This invention belongs to the field of oncology diagnostic and treatment equipment, specifically a convenient device for the combined puncture and efficient sampling of gastrointestinal tumors. Background Technology

[0002] In the field of oncology diagnosis and treatment, accurate diagnosis of gastrointestinal tumors plays a decisive role in the formulation of subsequent treatment plans. As a key means of obtaining tumor tissue for pathological analysis, the performance of the equipment used for puncture and sampling is of paramount importance.

[0003] Traditional gastrointestinal tumor biopsy and sampling devices often require medical staff to first penetrate the patient's digestive tract wall with a puncture needle to reach the tumor site. They also need to use auxiliary equipment such as syringes and negative pressure aspirators to aspirate tumor tissue fluid or obtain tissue samples, which undoubtedly increases the complexity of the procedure. This not only severely tests the operational skills and patience of medical staff but also significantly prolongs the entire sampling process, increasing the patient's pain and discomfort during the procedure. As shown in the patent document with publication number CN113842176A, although automated needle insertion control is achieved, multiple punctures are still required to collect samples from different sites.

[0004] Furthermore, from the perspective of sampling convenience, some existing devices often overlook the complex structure and limited space within the digestive tract, as well as the diverse locations and shapes of tumors. Many devices lack effective tissue expansion capabilities, making it difficult to create favorable conditions for sampling in confined spaces. In areas such as the esophagus and duodenum, the space around tumors is already narrow, and traditional devices cannot expand the tissues in these areas, making it difficult for the puncture needle and sampling instruments to accurately reach the target tumor region, and even more difficult to obtain a sufficient quantity and representative tumor specimen. This not only leads to sampling difficulties and increases the failure rate of the procedure, but may also affect the accuracy of subsequent pathological analysis due to insufficient or unrepresentative sample size, thus misleading the patient's diagnosis and treatment.

[0005] Therefore, it is necessary to propose a convenient digestive tract tumor puncture and high-efficiency sampling linkage device that can extract samples at different depths in a single puncture step, actively expand the sampling space, facilitate tumor puncture sampling, and enhance sampling efficiency and representativeness. Summary of the Invention

[0006] To address the aforementioned issues, the present invention aims to provide a convenient and efficient integrated device for gastrointestinal tumor puncture and sampling. The sampling component achieves simultaneous sampling at different depths through nested needles and sampling tubes. The puncture component stabilizes the deformation of the puncture needle using puncture parts and conical collars, reducing the cumbersome steps of changing puncture needles. The support component expands and supports the surrounding tissue using expansion rods and pressure sensors, providing space and field of vision for puncture and sampling, thus achieving convenient operation and rapid sampling.

[0007] To achieve the above objectives, the technical solution of the present invention is as follows: a convenient digestive tract tumor puncture and high-efficiency sampling linkage device, including a handle, a sampling component detachably connected to the handle, a puncture component provided at the end of the sampling component away from the handle, a support component fixedly connected to the outer periphery of the sampling component, a controller provided inside the handle, and the support component and the controller being signal connected.

[0008] A sampling component for simultaneously sampling samples at different depths using nested sampling needles;

[0009] The puncture assembly is used to perform punctures into the digestive tract and target lesions via a sheath-type puncture needle;

[0010] Support components are used to expand and support the digestive tract tissue surrounding the lesion using hydraulic technology.

[0011] The basic principle of the solution is as follows: the handle serves as the core of operation and control, and the sampling component, which can be detachably connected, enables the simultaneous acquisition of samples at different depths. Its nested sampling needle structure can adapt to the sampling needs of different layers of the tumor. The puncture component at the end of the sampling component uses a jacket-type puncture needle to complete the puncture operation of the digestive tract and lesion, and forms a linkage with the sampling component. The support component uses hydraulic technology to expand and support the digestive tract tissue around the lesion, providing a stable space for puncture and sampling. The controller receives the signal from the support component and realizes overall coordinated control, so that the puncture, sampling and support links are linked in an orderly manner.

[0012] The basic approach offers the following benefits: 1. By using nested sampling needles to obtain samples at different depths in a single procedure, it avoids the cumbersome process of multiple punctures required by traditional devices, significantly shortening sampling time and reducing patient discomfort. 2. It can simultaneously obtain tissue fluid and tissue samples from both the surface and deep layers of the tumor, ensuring the comprehensiveness and accuracy of pathological analysis and providing a reliable basis for doctors to develop precise treatment plans.

[0013] 2. The integrated design simplifies the operation process. Medical staff can control the entire device's puncture, sampling, and support processes via a handle, reducing operational difficulty, reliance on medical staff's operational skills, and improving diagnostic and treatment efficiency. It reduces the number of puncture and sampling steps and time, lowering the risk of tumor cell spread and infection during surgery, which is beneficial for patient postoperative recovery and prognosis.

[0014] 3. The hydraulic expansion function of the support component creates favorable conditions for puncture and sampling, especially suitable for tumor sampling in confined spaces such as the esophagus and duodenum, improving the sampling success rate. Equipped with a pressure sensor and controller, it can monitor the pressure of the support component in real time. When the pressure exceeds the threshold, the alarm module will promptly issue an alarm to remind medical staff to adjust the operation, ensuring the safety of the puncture and sampling process and preventing tissue tearing damage due to excessive pressure.

[0015] Furthermore, the sampling assembly includes a sampling sleeve, the bottom end of which is detachably connected to the handle. A sampling cap is threaded onto the bottom end of the sampling sleeve. A sampling chamber is opened inside the sampling sleeve, and several sampling tubes are provided in the sampling chamber. Both ends of the sampling tubes are equipped with silicone valves. The bottom end of each sampling tube is connected to a negative pressure tube, and the top end of each sampling tube is connected to a corrugated tube. A sampling needle is slidably connected inside the sampling sleeve. The sampling needle consists of several nested needles, with the number of needle layers corresponding to the number of sampling tubes. A sampling disc is fixedly connected to the bottom end of the sampling needle, and the top end of the corrugated tube is connected to the corresponding needle. The length of the needle at the top of the sampling needle gradually decreases as it approaches the sampling sleeve.

[0016] The advantages of the basic design are: 1. The sampling needle consists of several nested needle layers, with the number of needle layers corresponding to the number of sampling tubes. This design allows for the simultaneous acquisition of samples at different depths in a single puncture operation, significantly reducing the cumbersome steps of multiple punctures and needle replacements required by traditional devices.

[0017] 2. The length of the sampling needle gradually decreases as it approaches the sampling cannula. This design ensures that needles of different lengths can simultaneously acquire samples from different depths, avoiding the problem of unrepresentative samples caused by changes in sampling position in traditional devices. By simultaneously collecting samples from multiple depths, the comprehensiveness and accuracy of pathological analysis are significantly improved, helping to more accurately determine the pathological characteristics of tumors.

[0018] 3. The bottom end of the sampling cannula is detachably connected to the handle via threads, and a sampling cap is also threaded onto the bottom end of the sampling cannula. This detachable design facilitates the replacement of the sampling components by medical personnel, ensuring the hygiene and reusability of the device and preventing cross-infection.

[0019] 4. The silicone valves at both ends of the sampling tube ensure unidirectional sample flow during collection, preventing backflow or leakage and guaranteeing sample quality and integrity. This sealing design also helps prevent potential infection risks, ensuring the safety of the sampling process.

[0020] Furthermore, the sampling assembly also includes a sealing disc, which is fixedly connected to symmetrically arranged push plates. The sidewall of the sampling chamber is symmetrically provided with push grooves, and push blocks are slidably fitted in each push groove. The push plates are fixedly connected to the push blocks respectively. The outer sidewall of the push blocks is provided with push threads, and push rings are threadedly fitted in the push threads. The push rings are slidably fitted with the bottom sidewall of the sampling sleeve.

[0021] The beneficial effects of the basic design are: 1. Through the coordinated action of components such as the advancement plate, advancement block, advancement groove, advancement thread, and advancement ring, medical personnel can precisely adjust the advancement depth of the sampling needle. This design avoids the tissue damage and inaccurate sampling problems caused by uncontrollable puncture needle depth in traditional devices. The advancement plate is fixedly connected to the sealing disc, and the advancement block slides within the advancement groove. This structural design makes the sampling needle more stable during advancement, reduces the risk of needle deviation, and improves the accuracy and success rate of sampling.

[0022] 2. The advancing ring slides against the bottom side wall of the sampling cannula, allowing medical staff to easily control the advancement and retraction of the sampling needle by rotating the advancing ring. This simple and intuitive operation reduces the difficulty of operation for medical staff and improves the ease of use of the device.

[0023] 3. By precisely controlling the depth of the sampling needle insertion, the risk of the needle penetrating beyond the tumor area and into surrounding normal tissue is reduced. This design effectively reduces physical damage to normal tissue, decreases the probability of postoperative complications such as pain and bleeding, and also reduces the risk of tumor cell spread.

[0024] Furthermore, the puncture assembly includes several puncture components arranged in a ring at the top of the sampling needle tube. The puncture components are spliced ​​together to form a puncture needle. Each puncture component has several interlocking holes radially opened inside. Interlocking rods are slidably fitted in the interlocking holes of adjacent puncture components. A conical collar is slidably fitted at the top of the sampling tube. The outer wall of the conical collar has a closed thread. The closed thread is threaded to the bottom wall of the puncture component. A limit spring is fixedly connected to the inner wall of the bottom of each puncture component. The other end of each limit spring is fixedly connected to the outer wall of the corresponding sampling tube. A rotating rod is symmetrically fixedly connected to the bottom wall of the conical collar. A rotating groove is axially symmetrically opened inside the sampling tube. The rotating rod extends downward along the rotating groove. A rotating ring is rotatably fitted to the bottom side wall of the sampling tube. The rotating ring and the bottom end of the rotating rod are fixedly connected.

[0025] The beneficial effects of the basic design are: 1. The puncture assembly is formed by splicing together several annularly distributed puncture components at the tip of the sampling needle. This design provides stable structural support during puncture, reduces needle tip wobbling and deviation, and improves the accuracy and stability of puncture.

[0026] 2. Each puncture component has several radially interlocking holes, with interlocking rods slidingly engaged within the interlocking holes of adjacent puncture components. This design allows for relative movement between the puncture components within a certain range, thereby adjusting the shape of the puncture needle. During puncture, the opening or closing state of the puncture needle can be adjusted as needed to adapt to puncture and sampling functions, improving the flexibility and adaptability of the device. A conical collar slides at the top of the sampling cannula, with a closing thread on its outer wall. This closing thread engages with the bottom wall of the puncture component. By rotating the conical collar, the opening or closing of the puncture components can be easily controlled, enabling rapid adjustment of the puncture needle shape.

[0027] 3. Limiting springs are fixedly connected to the inner wall of the bottom of each puncture device, and the other end of each limiting spring is fixedly connected to the outer wall of the corresponding sampling cannula. The limiting springs not only limit the range of movement of the puncture device to prevent excessive opening or closing, but also provide a certain amount of elastic support during puncture, reducing needle wobbling and improving puncture stability.

[0028] Furthermore, the support assembly includes several expansion rods, and the outer wall of the sampling sleeve has several annularly distributed rod grooves. The expansion rods are respectively hinged to the top wall of the corresponding rod grooves. An expansion membrane is fixedly sleeved on the outer wall of the sampling sleeve. The expansion membrane is fixedly connected to the side walls of the expansion rods. Several pressure sensors are laid along the outer edge of the expansion membrane. A support rod is hinged to the middle of each expansion rod. A piston groove corresponding to the support rod is opened inside the sampling sleeve. A support piston is slidably fitted in each piston groove. The outer wall of each support piston is fixedly connected to the support rod. An annular groove is opened inside the sampling sleeve. The annular groove and the piston groove are connected. The pressure sensors are all connected to the controller signal.

[0029] The beneficial effects of the basic approach are: 1. The support assembly, through the cooperation of several dilating rods and a dilating membrane, can actively dilate the digestive tract tissue surrounding the lesion during puncture. The dilating rods are hinged to the top wall of the rod groove, and the dilating membrane is fixedly sleeved on the outer wall of the sampling cannula and fixedly connected to the side wall of the dilating rods. When dilation is needed, the dilating rods expand outward, causing the dilating membrane to expand, thereby increasing the digestive tract space and creating favorable operating conditions for puncture and sampling, especially suitable for tumor sampling in confined spaces such as the esophagus and duodenum. By dilating the digestive tract tissue surrounding the lesion, a clearer field of vision and more ample operating space are provided for the puncture needle and sampling needle, making the puncture and sampling process smoother. This not only improves the sampling success rate but also reduces sampling failures or insufficient samples due to insufficient space, thus improving the overall diagnostic and treatment efficiency.

[0030] 2. Several pressure sensors laid along the outer edge of the expansion membrane can monitor pressure changes in real time during the expansion process and transmit the data to the controller. The acquisition module in the controller receives the pressure data, and the communication module can read the positioning alarm data from the external monitoring equipment. The alarm module issues an alarm in a timely manner when the pressure data exceeds the threshold. This real-time monitoring and feedback mechanism ensures the safety of the expansion process and prevents tissue tearing damage caused by excessive pressure.

[0031] 3. The support component and sampling component are fixedly connected on their outer periphery, with the sampling cannula serving as the connecting link, ensuring the integrated design of the entire device. Medical staff can operate the puncture, sampling, and support functions uniformly through the controller inside the handle, simplifying the operation process and improving the ease of use of the device.

[0032] Furthermore, the support assembly also includes a hydraulic ring, which slides in conjunction with the bottom sidewall of the sampling sleeve. The sampling sleeve has symmetrically opened arc-shaped grooves pre-filled with liquid inside, and arc-shaped pistons slide in each of the arc-shaped grooves. The bottom outer sidewall of each arc-shaped piston has piston threads, which all engage with the inner thread of the hydraulic ring. The top of each piston groove is connected to a hydraulic pipe, which extends upward along the sampling sleeve, and the top of each hydraulic pipe is connected to the annular groove.

[0033] The beneficial effects of the basic design are: 1. The support assembly achieves precise hydraulic expansion control through the sliding fit between the hydraulic ring and the bottom sidewall of the sampling cannula, as well as the symmetrically pre-filled liquid arc grooves inside the sampling cannula. This design makes the expansion process more stable and controllable, allowing medical staff to adjust the expansion force according to actual needs, ensuring the safety and effectiveness of the expansion process.

[0034] 2. Through the cooperation of the hydraulic ring and the arc-shaped piston, the expansion force can be evenly distributed on the digestive tract tissues surrounding the lesion, reducing the risk of excessive local pressure. This uniform distribution of expansion force reduces the possibility of tissue tearing and damage, protects the patient's tissue structure, and lowers the risk of postoperative complications.

[0035] 3. Pressure changes in the hydraulic system can be monitored in real time by pressure sensors, and the data is transmitted to the controller. The alarm module within the controller promptly issues an alarm when the pressure exceeds the safety threshold, alerting medical personnel to adjust the operation and ensuring the safety of the expansion process. This real-time monitoring and feedback mechanism further enhances operational safety.

[0036] Furthermore, the handle is equipped with a negative pressure air pump and a battery. The output end of the negative pressure air pump is connected to a fixed tube, which extends upward through the sampling cover and is connected to the negative pressure tube. The negative pressure air pump and the battery are both connected to the controller signal.

[0037] The benefits of the basic design are: 1. The handle integrates a negative pressure air pump and a battery, making the entire device more compact and portable. Medical personnel can easily carry and operate the device without needing to connect to external equipment, improving the device's flexibility and applicability, especially suitable for emergency situations or mobile medical scenarios requiring rapid response.

[0038] 2. The built-in design of the negative pressure air pump and battery reduces interference from external connection pipes and power cords, lowering the risk of malfunctions due to loose or damaged external connections. This not only improves the durability of the device but also simplifies the operation process, reducing the number of components that medical staff need to manage during operation, thus improving convenience and safety.

[0039] Furthermore, both the bottom wall of the sampling cap and the top wall of the handle are fixedly connected with sealing rings that fit around the outer periphery of the fixed tube.

[0040] The beneficial effects of the basic design are: 1. Sealing rings are fixedly connected to the bottom wall of the sampling cap and the top wall of the handle. These sealing rings are fitted around the outer circumference of the fixed tube, effectively preventing leakage of negative pressure gas or liquid from the connection point during sampling. This sealing design ensures the efficient operation of the negative pressure system, avoids negative pressure loss due to poor sealing, and improves the efficiency and reliability of sampling.

[0041] 2. The sealing ring also prevents external contaminants from entering the sampling system, ensuring the quality and integrity of the collected samples. This is crucial for subsequent pathological analysis, as sample contamination can lead to erroneous diagnostic results.

[0042] Furthermore, the outer wall of the handle is covered with a friction layer, and the outer walls of the push ring, rotating ring and hydraulic ring are all textured with anti-slip patterns.

[0043] The beneficial effects of the basic design are: the friction layer on the outer wall of the handle and the anti-slip texture on the outer walls of the propulsion ring, rotating ring, and hydraulic ring significantly improve the grip stability for medical personnel during operation. This design reduces operational errors caused by hand slippage, especially in steps requiring fine adjustments, such as controlling the rotation of the propulsion ring, rotating ring, and hydraulic ring, ensuring the accuracy and stability of the operation.

[0044] Furthermore, the controller is equipped with a data acquisition module, a communication module, and an alarm module;

[0045] The data acquisition module is used to receive pressure data detected by the pressure sensor;

[0046] The communication module is used to read the location alarm data from the external monitoring device;

[0047] The alarm module is used to issue an alarm when the pressure data exceeds the threshold or based on location alarm data.

[0048] The beneficial effects of the basic solution are: 1. The acquisition module can receive pressure data detected by the pressure sensor in real time, ensuring that medical staff can understand the force exerted on the tissue by the expansion component at any time during operation. This real-time monitoring function helps medical staff adjust the expansion force according to the actual situation, avoiding affecting the sampling effect or causing tissue damage due to excessive or insufficient pressure.

[0049] 2. The communication module works in conjunction with external monitoring equipment to read location alarm data. This allows medical staff to accurately determine the position of the puncture needle, ensuring the accuracy of the puncture process, especially in the complex environment of the digestive tract, and preventing the puncture needle from deviating from the target tumor area.

[0050] 3. The alarm module promptly issues an alert when pressure data exceeds a preset threshold or when a positioning anomaly alarm is received. This alarm mechanism reminds medical staff to take immediate measures to prevent complications caused by excessive pressure leading to tissue tearing or needle misalignment, significantly improving operational safety. Attached Figure Description

[0051] Figure 1 This is an isometric view of the convenient digestive tract tumor puncture and efficient sampling linkage device in an embodiment of the present invention.

[0052] Figure 2 This is a top view of the convenient digestive tract tumor puncture and efficient sampling linkage device in an embodiment of the present invention.

[0053] Figure 3 This is a side cross-sectional view of the convenient digestive tract tumor puncture and high-efficiency sampling linkage device in an embodiment of the present invention.

[0054] Figure 4 for Figure 3 Enlarged view of section A.

[0055] Figure 5 for Figure 3 Enlarged view of section B.

[0056] Figure 6 A schematic diagram of the system setup within the controller.

[0057] The reference numerals in the accompanying drawings of the instruction manual include: 1. Handle; 2. Controller; 3. Propulsion ring; 4. Hydraulic ring; 5. Rotating ring; 6. Sampling sleeve; 7. Expansion membrane; 8. Puncture element; 9. Closing thread; 10. Negative pressure air pump; 11. Battery; 12. Fixing tube; 13. Sampling needle tube; 14. Rod groove; 15. Expansion rod; 17. Support rod; 18. Rotating rod; 19. Conical collar; 20. Limiting spring; 21. Interlocking rod; 22. Piston groove; 23. Annular groove; 24. Pressure sensor; 25. Sampling cover; 26. Negative pressure tube; 27. Silicone valve; 28. Sampling tube; 29. ​​Bellows; 30. Sealing disc; 31. Propulsion plate; 32. Propulsion block. Detailed Implementation

[0058] The following detailed description illustrates the specific implementation method:

[0059] Example 1

[0060] The basics are as follows: Figures 1 to 5 As shown: A convenient digestive tract tumor puncture and efficient sampling linkage device includes a handle 1, a sampling component detachably connected to the handle 1, a puncture component welded to the end of the sampling component away from the handle 1, a support component welded to the outer periphery of the sampling component, a controller 2 installed inside the handle 1, and the support component and the controller 2 being signal connected.

[0061] The sampling assembly is used to simultaneously sample samples at different depths using nested sampling needles. The sampling assembly includes a sampling sleeve 6, the bottom of which is detachably connected to a handle 1 via a thread. A sampling cap 25 is threaded onto the bottom of the sampling sleeve 6. A sampling chamber is opened inside the sampling sleeve 6, and several sampling tubes 28 are installed inside the sampling chamber. Silicone valves 27 are laid at both ends of the sampling tubes 28. A negative pressure tube 26 is connected to the bottom of each sampling tube 28, and a corrugated tube 29 is connected to the top of each sampling tube 28. A sampling needle tube 13 is slidably connected inside the sampling sleeve 6. The sampling needle tube 13 consists of several nested needle tubes, with the number of needle tube layers corresponding to the number of sampling tubes 28. A sampling disc is attached to the bottom of the sampling needle tube 13, and the top of the corrugated tube 29 is connected to the corresponding needle tube. The length of the needle tube at the top of the sampling needle tube 13 gradually decreases as it approaches the sampling sleeve 6.

[0062] The sampling assembly also includes a sealing disc 30, to which symmetrically arranged push plates 31 are bonded. The sidewall of the sampling chamber has symmetrical push grooves, and push blocks 32 are slidably fitted in each push groove. The push plates 31 are bonded to the push blocks 32 respectively. The outer sidewall of the push blocks 32 has push threads, and push rings 3 are threadedly fitted in the push threads. The push rings 3 are slidably fitted with the bottom sidewall of the sampling sleeve 6.

[0063] The puncture assembly is used to puncture the digestive tract and target lesions using a sheath-type puncture needle. The puncture assembly includes several puncture components 8 arranged in a ring at the top of the sampling needle tube 13. The puncture components 8 are spliced ​​together close to each other to form a puncture needle. Each puncture component 8 has several interlocking holes radially opened inside. Interlocking rods 21 are slidably fitted in the interlocking holes of adjacent puncture components 8. A conical collar 19 is slidably fitted at the top of the sampling tube 6. The outer wall of the conical collar 19 has a closing thread 9. The closing thread 9 is threadedly fitted to the bottom wall of the puncture component 8. Limiting springs 20 are glued to the inner wall of the bottom of each puncture component 8. The other end of each limiting spring 20 is glued to the outer wall of the corresponding sampling tube 6. A rotating rod 18 is symmetrically fixedly connected to the bottom wall of the conical collar 19. A rotating groove is symmetrically opened axially inside the sampling tube 6. The rotating rod 18 extends downward along the rotating groove. A rotating ring 5 is rotatably fitted to the bottom side wall of the sampling tube 6. The rotating ring 5 is glued to the bottom end of the rotating rod 18.

[0064] A support assembly is used to expand and support the digestive tract tissue around the lesion using hydraulic technology. The support assembly includes several expansion rods 15. Several annularly distributed rod grooves 14 are opened on the outer wall of the sampling sleeve 6. The expansion rods 15 are respectively hinged to the top wall of the corresponding rod grooves 14. An expansion membrane 7 is adhered to the outer wall of the sampling sleeve 6. The expansion membrane 7 is adhered to the side wall of the expansion rods 15. Several pressure sensors 24 are laid on the outer edge of the expansion membrane 7. A support rod 17 is hinged to the middle of each expansion rod 15. A piston groove 22 corresponding to the support rod 17 is opened in the sampling sleeve 6. A support piston is slidably fitted in each piston groove 22. The outer wall of each support piston is integrally formed with the support rod 17. An annular groove 23 is opened in the sampling sleeve 6. The annular groove 23 is connected to the piston groove 22. The pressure sensors 24 are all signal connected to the controller 2.

[0065] The support assembly also includes a hydraulic ring 4, which slides in conjunction with the bottom sidewall of the sampling sleeve 6. The sampling sleeve 6 has symmetrical arc-shaped grooves pre-filled with liquid inside, and arc-shaped pistons slide in each of the arc-shaped grooves. The bottom outer sidewall of each arc-shaped piston has a piston thread, which is in conjunction with the inner thread of the hydraulic ring 4. The top of each piston groove 22 is connected to a hydraulic pipe, which extends upward along the sampling sleeve 6, and the top of each hydraulic pipe is connected to the annular groove 23.

[0066] The handle 1 houses a negative pressure air pump 10 and a battery 11. The output end of the negative pressure air pump 10 is connected to a fixed tube 12, which extends upward through the sampling cover 25 and is connected to the negative pressure tube 26. Both the negative pressure air pump 10 and the battery 11 are connected to the controller 2. The outer wall of the handle 1 is covered with a friction layer, and the outer walls of the push ring 3, the rotating ring 5, and the hydraulic ring 4 are all textured with anti-slip grooves. The bottom wall of the sampling cover 25 and the top wall of the handle 1 are both bonded with sealing rings that fit around the fixed tube 12.

[0067] The specific implementation process is as follows: In order to ensure the representativeness and integrity of the sample, the existing tumor tissue puncture sampling often requires multiple punctures. After the puncture, the puncture needle needs to be disassembled and connected to a negative pressure pump to aspirate the tissue fluid. This greatly increases the cumbersomeness of the sampling work, prolongs the patient's suffering time, and because the equipment required for puncture sampling is relatively scattered and bulky, it is difficult to adapt to the use environment in emergency situations and remote areas.

[0068] When using this device for gastrointestinal tumor puncture sampling, first firmly grip the device using the friction layer on the outer wall of the handle 1. Tightly connect the bottom end of the sampling sleeve 6 of the sampling assembly to the handle 1 via threads. The sampling cap 25 is located at the bottom end of the sampling sleeve 6. At this time, the fixing tube 12 aligns with the hole on the sampling cap 25 and connects to the negative pressure tube 26 at the bottom end of the sampling tube 28. The sealing rings on the bottom wall of the sampling cap 25 and the top wall of the handle 1 ensure a tight seal at the connection, preventing negative pressure leakage. The battery 11 powers the negative pressure air pump 10 and controller 2 inside the handle 1, completing the assembly preparation of the device. Figure 1 and Figure 2 As shown.

[0069] Once the device's tip punctures into the patient's digestive tract and approaches the target lesion, the hydraulic ring 4 of the support assembly is rotated. Its anti-slip textured outer wall facilitates force application. The threads on the inner wall of the hydraulic ring 4 engage with the piston threads at the bottom of the arc-shaped piston, causing the arc-shaped piston to slide upwards within the arc-shaped groove inside the sampling cannula 6. The pre-stored liquid in the arc-shaped groove is forced into the annular groove 23 via a hydraulic tube, and then distributed from the annular groove 23 to each piston groove 22, pushing the support piston within the piston groove 22 outwards. The support piston drives the hinged support rod 17, causing the expansion rod 15 to rotate and unfold around the hinge point on the top wall of the rod groove 14, expanding the expansion membrane 7 like an umbrella. This provides support and expansion to the digestive tract tissue surrounding the lesion, increasing the surrounding space while the umbrella-shaped structure does not impede the movement of the tip. The pressure sensor 24 along the outer edge of the expansion membrane 7 transmits tissue pressure data to the controller 2 in real time, ensuring the expansion force is within a safe range and avoiding excessive expansion that could damage the tissue, thus creating a stable and clear space for subsequent operations.

[0070] Next, the puncture procedure is performed. The rotating ring 5 of the puncture assembly is rotated, which, via the rotating rod 18, drives the conical collar 19 to slide along the top of the sampling cannula 6. The closed thread 9 on the outer wall of the conical collar 19 engages with the threaded bottom wall of the puncture component 8, causing the annularly distributed puncture components 8 to approach each other and splice together to form a complete puncture needle. The interlocking rods 21 in the interlocking holes of adjacent puncture components 8 ensure a stable splice, and the limiting springs 20 are stretched to provide a reverse restraint force, ensuring the stability of the puncture needle's shape. Guided by the puncture needle, the device accurately penetrates the digestive tract wall to reach the tumor lesion. After the puncture is completed, the rotating ring 5 is rotated in the reverse direction, and the limiting springs 20 pull the puncture components 8 back to their original position, preventing the puncture needle from remaining and causing continuous damage to the tissue. Figure 3 and Figure 4 As shown.

[0071] The sampling process is then initiated. The advancing ring 3 of the sampling assembly is rotated; its anti-slip texture facilitates operation. The advancing ring 3 engages with the advancing block 32 via its threaded engagement, causing the advancing block 32 to slide along the advancing groove. The advancing block 32 pushes the sampling disc via the advancing plate 31, extending the sampling needle 13 within the sampling sleeve 6. The sampling needle 13 consists of multiple nested needles, with the length of the tip needle gradually decreasing as it approaches the sampling sleeve 6, thus corresponding to lesions at different depths of the tumor. Simultaneously, the negative pressure pump 10 is activated. Negative pressure is transmitted to the sampling tube 28 via the fixing tube 12 and negative pressure tube 26. The corrugated tube 29 at the tip of the sampling tube 28 stretches as the sampling needle 13 extends, ensuring continuous negative pressure at the tip of the needle. When the needle contacts tumor tissue at different depths, the tissue sample, under negative pressure, enters the corresponding sampling tube 28 through the needle and corrugated tube 29. The silicone valves 27 at both ends of the sampling tube 28 prevent sample backflow, achieving simultaneous collection of samples at different depths. Figure 5 As shown.

[0072] After sampling is completed, the push ring 3 is rotated in the opposite direction, and the sampling needle 13 retracts into the sampling sleeve 6. Each sampling tube 28 independently stores samples at different depths. The hydraulic ring 4 is rotated in the opposite direction, the arc-shaped piston is reset, the hydraulic oil flows back, the support piston drives the support rod 17 to retract, the expansion rod 15 folds back into the rod groove 14, the expansion membrane 7 contracts, the support on the tissue is released, and the human body is removed. Finally, the sampling assembly is removed from the handle 1, and the sampling cap 25 is removed to take out the sampling tube 28 for pathological analysis.

[0073] Throughout the process, controller 2 receives signals from pressure sensor 24 of the support component, monitors tissue pressure in real time, and issues an alarm through the alarm module when the pressure exceeds the threshold, ensuring operational safety. Each component is connected by threads for quick assembly and disassembly. The anti-slip design of the push ring 3, rotating ring 5, and hydraulic ring 4 enhances ease of operation. The nested sampling needle 13 and the independent sampling tube 28, in conjunction with the negative pressure system, achieve precise layered sampling. The interlocking structure of the puncture component ensures puncture stability. The hydraulically driven expansion and pressure monitoring of the support component balance operating space and tissue safety, ultimately achieving a comprehensive effect of efficient linkage between puncture and sampling, convenient operation, accurate sampling, and high safety and reliability.

[0074] Example 2

[0075] The difference from the above embodiments is that, as shown in the appendix Figure 6 As shown: Controller 2 is equipped with a data acquisition module, a communication module, and an alarm module;

[0076] The data acquisition module is used to receive pressure data detected by pressure sensor 24;

[0077] The communication module is used to read the location alarm data from the external monitoring device;

[0078] The alarm module is used to issue an alarm when the pressure data exceeds the threshold or based on location alarm data.

[0079] The specific implementation process is as follows: During the puncture and sampling process, the controller 2, as the core control unit, participates in the operation throughout. When the expansion membrane 7 of the support component unfolds to support the tissue around the lesion, the pressure sensor 24 on the outer edge of the expansion membrane 7 detects the pressure on the tissue in real time and continuously transmits the data to the acquisition module of the controller 2. The acquisition module receives and performs preliminary processing on this pressure data to monitor the expansion force in real time and avoid damage to the tissue due to excessive expansion.

[0080] Meanwhile, the communication module of controller 2 maintains a connection with the external monitoring device and reads the positioning alarm data transmitted by the device in real time. This data includes the device's location information in the digestive tract and possible abnormal positioning situations, providing accurate location reference for operation.

[0081] During the puncture procedure, if the pressure data detected by the pressure sensor 24 exceeds the preset safety threshold of the controller 2, the acquisition module will feed this information back to the alarm module, which will immediately activate the alarm to remind medical staff to adjust the dilation force. When the communication module reads the positioning alarm data issued by the external monitoring device, such as when the device deviates from the target lesion position or the puncture is too deep, the alarm module will also respond and sound an alarm in a timely manner to ensure that the puncture operation is always carried out within a safe and accurate range.

[0082] During the sampling process, the acquisition module continuously monitors the pressure data to ensure the stability of the support, the communication module synchronously confirms the device position, and the alarm module is always on standby to issue timely warnings in case of abnormal pressure or positioning deviation.

[0083] Through the coordinated operation of the acquisition module, communication module and alarm module within controller 2, real-time monitoring and early warning of abnormalities of tissue pressure and device position during puncture sampling are achieved, effectively improving the safety and accuracy of the operation and ensuring that the entire puncture sampling process is completed efficiently and reliably.

[0084] Specific experimental procedure: Performance verification experiment of the convenient gastrointestinal tumor puncture and high-efficiency sampling linkage device.

[0085] I. Experimental Objective

[0086] The experiment aimed to verify the efficiency of the device in completing puncture and sampling in a narrow cavity in a single procedure; evaluate the ability of the layered sampling technique to capture superficial and deep tumor tissues; and test the safety control performance of the hydraulic support system.

[0087] II. Experimental Materials and Methods

[0088] Experimental equipment and samples

[0089] Testing device: The linkage device described in the patent (including controller 2, negative pressure air pump 10, and hydraulic system);

[0090] Control group equipment: conventional 18G puncture needle + 5ml syringe kit;

[0091] Simulation environment: A custom-made transparent medical silicone digestive tract model (including the tortuous structure of the esophagus and duodenum, with a minimum cavity diameter of 2.5cm);

[0092] Tumor mimicry: Agar-gelatin complex (1.5–3 cm in diameter), surface impregnated with red water-soluble dye (simulating superficial tumors), core embedded with 1 mm diameter black ferrite magnetic beads (simulating deep lesions);

[0093] Monitoring equipment: high-definition endoscopic camera system, digital pressure recorder, stopwatch.

[0094] Experimental Groups

[0095] Experimental group (patented device group): Operation procedure: support expansion → single puncture → simultaneous layered sampling;

[0096] Sample size: 30 independent operations.

[0097] Control group (traditional method group): Procedure: puncture needle insertion → change syringe and aspirate 3 times (depth 0.5cm / 1.0cm / 1.5cm);

[0098] Sample size: 30 independent operations.

[0099] Evaluation indicators

[0100] Operational efficiency: Total time (seconds) from puncture to sampling completion, number of instrument operations;

[0101] Sampling quality: Shallow dye capture rate = (recovered dye mass / initial dye mass) × 100%;

[0102] Deep magnetic bead recovery rate = (number of recovered magnetic beads / initial number of buried beads) × 100%;

[0103] Safety: Tear rate of silicone model; Accuracy of overpressure alarm (preset threshold 20kPa)

[0104] III. Experimental Procedure

[0105] 1. Model preprocessing

[0106] The tumor simulant was fixed to the descending part of the duodenum (the narrowest region) of the silicone model, and its location was confirmed by endoscopy. The pressure recorder was connected to the dilation membrane 7 sensor and the zero point was calibrated.

[0107] 2. Experimental group operation

[0108] Hydraulic support stage: Rotate hydraulic ring 4 clockwise until the pressure reading stabilizes at 15 kPa (75% of the safety threshold), and record the diameter of the cavity after expansion.

[0109] Puncture and sampling stage: Rotate the rotating ring 5 to close the 6 puncture pieces 8 to form a conical needle, which is then inserted into the simulated tumor.

[0110] The rotating propulsion ring 3 pushes the three-layer nested sampling needle 13 to the maximum depth (1.5cm for the long needle and 0.5cm for the short needle).

[0111] Start the negative pressure air pump 10 (-80kPa, 10 seconds) and simultaneously extract three layers of samples.

[0112] Exit procedure: Retract sampling needle 13 in reverse order → Close puncture device 8 → Release hydraulic support → Exit device.

[0113] 3. Control group procedure

[0114] The puncture needle penetrates the simulated tumor surface.

[0115] Remove the puncture needle and replace it with a syringe to aspirate a sample at a depth of 0.5 cm (simulating a shallow layer).

[0116] Repeat the puncture and aspirate samples at depths of 1.0 cm (middle layer) and 1.5 cm (deep layer).

[0117] 4. Data Collection

[0118] The timer records the time elapsed from the first contact with the model to the completion of sampling.

[0119] Dissecting tumor mimicry: Weigh the residual dye and use a magnet to collect the residual magnetic beads.

[0120] Check the inner wall of the silicone model for tears or damage.

[0121] IV. Experimental Results

[0122] As shown in the table below:

[0123] Table 1. Comparison of operational efficiency (mean ± standard deviation)

[0124]

[0125] Table 2. Sampling Integrity Analysis

[0126]

[0127] Table 3. Safety Results

[0128]

[0129] *Note: The device triggered an alarm in each of the five instances where pressure exceeding 20 kPa was artificially created.

[0130] V. Experimental Conclusions

[0131] This patented device reduces the average operation time to 41% of the traditional method (89.3s: 217.5s, P<0.001), and completes the entire procedure with a single puncture, avoiding the risks of operation interruption and contamination caused by multiple instrument changes.

[0132] The nested needle design enabled a deep magnetic bead acquisition rate of 96.4%, which was 52.5% higher than the control group (P < 0.001), addressing the clinical challenge of insufficient sampling of deep lesions using traditional methods. No significant difference was observed in superficial sampling, indicating that the device retains basic sampling capabilities.

[0133] The hydraulic support system applied pressure evenly, and no tearing of the silicone model occurred in the experimental group, while the control group suffered a 13.3% injury rate due to repeated punctures. The pressure over-limit alarm system had a 100% response rate, achieving precise closed-loop control of the expansion force.

[0134] The device was successfully expanded to an operating space of 4.1±0.3cm in the original duodenal model with a diameter of 2.5cm, providing technical support for tumor sampling in complex anatomical locations.

[0135] It should be noted that, in this document, relational terms such as "first" and "second" are used only to distinguish one entity or operation from another, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Furthermore, the terms "comprising," "including," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements includes not only those elements but also other elements not expressly listed, or elements inherent to such process, method, article, or apparatus.

[0136] The above descriptions are merely embodiments of the present invention. Commonly known structures and characteristics are not described in detail here. Those skilled in the art are aware of all common technical knowledge in the field prior to the application date or priority date, are aware of all existing technologies in that field, and have the ability to apply conventional experimental methods prior to that date. Those skilled in the art can, under the guidance of this application, improve and implement this solution in combination with their own capabilities. Some typical known structures or methods should not be obstacles for those skilled in the art to implement this application. It should be noted that those skilled in the art can make several modifications and improvements without departing from the structure of the present invention. These should also be considered within the scope of protection of the present invention, and will not affect the effectiveness of the implementation of the present invention or the practicality of the patent. The scope of protection claimed in this application should be determined by the content of its claims, and the specific embodiments described in the specification can be used to interpret the content of the claims.

Claims

1. A convenient device for combined puncture and efficient sampling of gastrointestinal tumors, comprising a handle (1), characterized in that: A sampling component is detachably connected to the handle (1). A puncture component is provided at the end of the sampling component away from the handle (1). A support component is fixedly connected to the outer periphery of the sampling component. A controller (2) is provided inside the handle (1). The support component is signal connected to the controller (2). A sampling component for simultaneously sampling samples at different depths using nested sampling needles; The puncture assembly is used to perform punctures into the digestive tract and target lesions via a sheath-type puncture needle; Support components are used to expand and support the digestive tract tissue surrounding the lesion using hydraulic technology.

2. The convenient gastrointestinal tumor puncture and high-efficiency sampling linkage device according to claim 1, characterized in that: The sampling assembly includes a sampling sleeve (6), the bottom end of which is detachably connected to a handle (1). A sampling cap (25) is threaded onto the bottom end of the sampling sleeve (6). A sampling chamber is opened inside the sampling sleeve (6), and several sampling tubes (28) are provided inside the sampling chamber. Both ends of the sampling tubes (28) are provided with silicone valves (27). The bottom end of each sampling tube (28) is connected to a negative pressure tube (26), and the top end of each sampling tube (28) is connected to a negative pressure tube (26). There is a corrugated tube (29), and a sampling needle tube (13) is slidably connected inside the sampling sleeve (6). The sampling needle tube (13) is composed of several nested needle tubes. The number of needle tube layers corresponds to the number of sampling tubes (28). A sampling plate is fixedly connected to the bottom end of the sampling needle tube (13). The top end of the corrugated tube (29) is connected to the corresponding needle tube. The length of the needle tube at the top of the sampling needle tube (13) gradually decreases as it approaches the sampling sleeve (6).

3. The convenient gastrointestinal tumor puncture and high-efficiency sampling linkage device according to claim 1, characterized in that: The sampling assembly also includes a sealing disc (30), which is fixedly connected to symmetrically arranged push plates (31). The sidewall of the sampling chamber is symmetrically provided with push grooves, and push blocks (32) are slidably fitted in each push groove. The push plates (31) are fixedly connected to the push blocks (32) respectively. The outer sidewall of the push blocks (32) is provided with push threads, and push rings (3) are threadedly fitted in the push threads. The push rings (3) are slidably fitted with the bottom sidewall of the sampling sleeve (6).

4. The convenient digestive tract tumor puncture and high-efficiency sampling linkage device according to claim 1, characterized in that: The puncture assembly includes several annularly distributed puncture components (8) at the top of the sampling needle tube (13). The puncture components (8) are spliced ​​together close to each other to form a puncture needle. Each puncture component (8) has several interlocking holes radially opened inside. Interlocking rods (21) are slidably fitted in the interlocking holes of adjacent puncture components (8). A conical collar (19) is slidably fitted at the top of the sampling sleeve (6). The outer wall of the conical collar (19) has a closed thread (9). The closed thread (9) is threadedly fitted to the bottom wall of the puncture component (8). A limiting spring (20) is fixedly connected to the inner wall of the bottom of the puncture piece (8). The other end of the limiting spring (20) is fixedly connected to the outer wall of the corresponding sampling sleeve (6). A rotating rod (18) is symmetrically fixedly connected to the bottom wall of the conical collar (19). A rotating groove is symmetrically opened in the axial direction inside the sampling sleeve (6). The rotating rod (18) extends downward along the rotating groove. A rotating ring (5) is rotatably fitted to the bottom side wall of the sampling sleeve (6). The rotating ring (5) is fixedly connected to the bottom end of the rotating rod (18).

5. The convenient gastrointestinal tumor puncture and high-efficiency sampling linkage device according to claim 1, characterized in that: The support assembly includes several expansion rods (15), and several rod grooves (14) arranged in a ring on the outer wall of the sampling sleeve (6). The expansion rods (15) are respectively hinged to the top wall of the corresponding rod grooves (14). An expansion membrane (7) is fixedly sleeved on the outer wall of the sampling sleeve (6). The expansion membrane (7) is fixedly connected to the side wall of the expansion rods (15). Several pressure sensors (24) are laid on the outer edge of the expansion membrane (7). A support rod (17) is hinged in the middle of each expansion rod (15). A piston groove (22) corresponding to the support rod (17) is opened in the sampling sleeve (6). A support piston is slidably fitted in each piston groove (22). The outer wall of each support piston is fixedly connected to the support rod (17). An annular groove (23) is opened in the sampling sleeve (6). The annular groove (23) is connected to the piston groove (22). The pressure sensors (24) are all signal connected to the controller (2).

6. The convenient gastrointestinal tumor puncture and high-efficiency sampling linkage device according to claim 1, characterized in that: The support assembly also includes a hydraulic ring (4), which slides with the bottom side wall of the sampling sleeve (6). The sampling sleeve (6) has symmetrical arc-shaped grooves pre-filled with liquid inside. Arc-shaped pistons slide in the arc-shaped grooves. The bottom outer side wall of the arc-shaped pistons has piston threads. The piston threads are threaded with the inner wall of the hydraulic ring (4). The top of the piston groove (22) is connected to a hydraulic pipe. The hydraulic pipes extend upward along the sampling sleeve (6). The top of the hydraulic pipes is connected to the annular groove (23).

7. The convenient digestive tract tumor puncture and high-efficiency sampling linkage device according to claim 1, characterized in that: The handle (1) is equipped with a negative pressure air pump (10) and a storage battery (11). The output end of the negative pressure air pump (10) is connected to a fixed tube (12). The fixed tube (12) extends upward through the sampling cover (25) and is connected to the negative pressure tube (26). The negative pressure air pump (10) and the storage battery (11) are both connected to the controller (2) via signal.

8. The convenient digestive tract tumor puncture and high-efficiency sampling linkage device according to claim 2, characterized in that: The bottom wall of the sampling cover (25) and the top wall of the handle (1) are both fixedly connected with sealing rings that fit around the outer periphery of the fixed tube (12).

9. The convenient digestive tract tumor puncture and high-efficiency sampling linkage device according to claim 7, characterized in that: The outer wall of the handle (1) is covered with a friction layer, and the outer walls of the push ring (3), the rotating ring (5) and the hydraulic ring (4) are all covered with anti-slip textures.

10. The convenient gastrointestinal tumor puncture and high-efficiency sampling linkage device according to claim 1, characterized in that: The controller (2) is equipped with a data acquisition module, a communication module and an alarm module; The acquisition module is used to receive pressure data detected by the pressure sensor (24); The communication module is used to read the location alarm data from the external monitoring device; The alarm module is used to issue an alarm when the pressure data exceeds the threshold or based on location alarm data.

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