基于经颅超声刺激的无创神经调控系统
The non-invasive neuromodulation system based on transcranial ultrasound stimulation solves the problem of insufficient spatial resolution and depth in deep brain region stimulation, achieving precise modulation of the hippocampus and amygdala. Combined with online mode for sleep neuromodulation, it is suitable for a wide range of applications.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- BEIJING NORMAL UNIVERSITY
- Filing Date
- 2025-07-02
- Publication Date
- 2026-07-17
AI Technical Summary
Existing non-invasive neuromodulation techniques have limited spatial resolution and depth when stimulating deep brain regions, and lack causal exploration of cognitive and behavioral changes, especially the research gaps in precise hippocampal stimulation and the role of the amygdala in anxiety decision-making.
A non-invasive neuromodulation system based on transcranial ultrasound stimulation is used. The focal length of the ultrasound transducer is calibrated through acoustic simulation. Combined with data acquisition and skin reconstruction, the target trajectory is determined. The Brainsight navigation system and Babelbrain software are used to calculate the focal position. A gel pad of a specific shape is used to ensure effective propagation of ultrasound waves and achieve precise stimulation.
It achieves high-precision stimulation of deep brain regions such as the hippocampus and amygdala, improves spatial resolution and stimulation depth, can analyze changes in nervous system activity, is suitable for general subjects, and can perform sleep neuromodulation in online mode.
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Figure CN120983832B_ABST