一种ZIF-8 / Hb混合LB薄膜的制备工艺
By preparing ZIF-8/Hb nanoparticles and ultrasonically dispersing them in an isooctane solution of sodium dioctyl succinate sulfonate, combined with π-A curves and a multifunctional LB film stretching machine, the problem of ZIF-8/Hb nanoparticles forming films at the gas-liquid interface was solved, achieving a highly stable and highly sensitive biosensing interface. This enabled the controllable preparation and performance customization of ZIF-8/Hb hybrid LB films.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- JILIN INST OF CHEM TECH
- Filing Date
- 2025-08-28
- Publication Date
- 2026-07-17
AI Technical Summary
ZIF-8/Hb nanoparticles tend to aggregate and settle in aqueous phases, making it difficult to form a uniform monolayer at the gas-liquid interface. LB films constructed using traditional physical mixing methods suffer from pore collapse and Hb leakage. Pure Hb is difficult to form a film independently, and ZIF-8 molecules are loosely arranged and collapse under pressure, making it difficult to support multiple rounds of film stretching operations.
By preparing ZIF-8/Hb nanoparticles and ultrasonically dispersing them in an isooctane solution of sodium dioctyl succinate sulfonate, combined with π-A curves and a multifunctional LB film stretching machine, and setting intelligent film stretching parameters, the preparation of ZIF-8/Hb mixed LB films was achieved, thus solving the bottleneck of nanoparticle film formation and the retention of bioactivity.
The interfacial stability of ZIF-8/Hb nanoparticles was achieved, the bioelectrochemical activity of Hb was preserved, a highly sensitive biosensing interface was provided, and the film performance was customized through intelligent process parameter control.
Smart Images
Figure CN121045601B_ABST