视网膜血管标志物概念感知与多模态融合的冠状动脉病变检测方法

By constructing a cross-sectional dataset of coronary artery lesions and a conceptual awareness model of retinal vascular markers, we achieved multimodal fusion of retinal vascular morphology and clinical characteristics, solving the invasiveness problem of existing coronary artery lesion diagnosis, improving the accuracy and interpretability of detection, and providing a non-invasive diagnostic method.

CN121074010BActive Publication Date: 2026-07-17NORTHEAST FORESTRY UNIV

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
NORTHEAST FORESTRY UNIV
Filing Date
2025-09-28
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

Current diagnosis of coronary artery disease mainly relies on highly invasive coronary angiography, and the use of existing retinal vascular markers is insufficient, resulting in inadequate accuracy and interpretability of test results.

Method used

A cross-sectional dataset of coronary artery lesions was constructed, retinal fundus images and clinical information were collected, vascular markers were extracted using a retinal arteriovenous segmentation model, vascular morphological changes were quantified through a biomarker concept perception module, and vascular features and clinical features were fused by a clinical feature representation module and a cross-modal attention aggregation module. The model was trained until convergence for the diagnosis of coronary artery lesions.

Benefits of technology

It improves the accuracy and interpretability of coronary artery disease diagnosis, provides a non-invasive diagnostic method, and reduces the burden on patients.

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Abstract

视网膜血管标志物概念感知与多模态融合的冠状动脉病变检测方法,本发明涉及冠状动脉病变的检测技术中,现有方法难以有效利用视网膜血管标志物并实现多模态特征融合检测的问题。冠状动脉病变是威胁人类健康的主要心血管疾病,早期诊断意义重大。传统检测依赖造影检查,存在创伤性和高成本等局限。视网膜血管反映全身微循环状态,结合临床指标为无创检测提供新途径。本发明提出视网膜血管标志物概念感知与多模态融合的冠状动脉病变检测方法。该方法优势如下:(1)计算血管密度和弯曲度等标志物,量化视网膜血管形态(2)通过跨模态注意力聚合机制融合图像特征与临床特征,提高冠状动脉病变诊断性能。本发明可用于冠状动脉病变辅助检测。
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