一种与鸡胸肌重性状相关的分子标记及其应用

By screening the chicken genome through genome-wide association analysis, the SNP locus Chr13:15953853, which is associated with chicken breast muscle weight, was identified. This solved the problem of low efficiency in traditional breeding methods, enabled early genetic assessment and efficient breeding, and promoted the rapid selection and breeding of high-quality chicken breeds.

CN121137182BActive Publication Date: 2026-07-17LINGNAN MODERN AGRI SCI & TECH GUANGDONG LAB +1

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
LINGNAN MODERN AGRI SCI & TECH GUANGDONG LAB
Filing Date
2025-11-05
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

Traditional broiler breeding relies on phenotypic selection methods, which are inefficient and make it difficult to accurately predict genetic potential in early stages of an individual. Existing molecular marker-assisted selection technology has limitations in the study of chicken breast muscle weight traits, and there is a lack of effective molecular marker and genomic selection methods.

Method used

Genome-wide association analysis (GWAS) was used to screen for candidate genes and SNPs that are significantly associated with breast muscle weight in chickens, especially the SNP site Chr13:15953853 on chromosome 13 of the chicken genome. Chickens with the genotype GG or GA showed higher breast muscle weight, while those with the AA genotype showed lower weight. This provides a scientific basis for early genetic assessment and breeding selection.

Benefits of technology

This enables accurate prediction of chicken breast muscle weight traits at an early stage, shortens the generation interval in breeding, accelerates the breeding process of high-quality chicken breeds, and improves breeding and selection efficiency.

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Abstract

本发明公开了一种与鸡胸肌重性状相关的分子标记及其应用,属于家禽育种技术领域。所述分子标记的SNP位点位于鸡基因组13染色体的第15953853位碱基,所述SNP位点存在G / A突变;所述鸡基因组在Ensemble数据库的登录号为GRCg6a_release95。本发明选择505只麻黄鸡作为全基因组关联分析的实验对象,收集胸肌重性状,并对胸肌重性状进行全基因组关联分析,检测到747个与胸肌重显著关联的SNPs。并针对其中的部分SNP位点与胸肌重性状进行验证分析,最终筛选出本发明提供的所述分子标记,为选育与胸肌重性状相关的鸡品种提供了理论支撑。
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