一种检测SNP分子标记的试剂盒在高产奶牛筛选中的应用

By using a kit to detect SNP molecular markers, superior alleles are selected and the frequency of the AG genotype is increased generation by generation. This solves the problem of difficulty in increasing the total milk yield of dairy cows during lactation in traditional methods, realizes efficient molecular marker-assisted breeding, and improves the production performance and economic benefits of dairy cows.

CN121227902BActive Publication Date: 2026-07-17NORTHWEST A & F UNIV
View PDF 2 Cites 0 Cited by

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
NORTHWEST A & F UNIV
Filing Date
2025-11-26
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

Traditional phenotypic selection methods are difficult to increase the total milk yield of dairy cows during lactation in the short term, are greatly affected by environmental factors, and genome-wide association studies have insufficient analytical power when the sample size and density are insufficient, making it difficult to accurately locate the genes that affect the traits.

Method used

To develop a kit for detecting SNP molecular markers, by selecting dominant alleles, increasing the frequency of the AG genotype generation by generation, eliminating the GG genotype, retaining the AG genotype in breeding cattle, and using primer pairs for PCR amplification and sequencing to determine the SNP sites, thus achieving efficient and accurate molecular marker-assisted breeding.

Benefits of technology

It has accelerated the progress of cattle genetic improvement, increased the total milk production of breeding cattle during lactation, improved economic benefits, and bred superior breeding cattle with high milk production traits.

✦ Generated by Eureka AI based on patent content.

Smart Images

  • Figure CN121227902B_ABST
    Figure CN121227902B_ABST
Patent Text Reader

Abstract

本发明涉及分子生物学技术领域,具体公开了一种检测SNP分子标记的试剂盒在高产奶牛筛选中的应用,所述SNP分子标记的核苷酸序列如SEQ ID NO.1所示,所述的SEQ ID NO.1序列中第2694位的N表示G或A,该位点碱基的多态性影响牛泌乳期的产奶量,其中,AG基因型的牛的泌乳期总产奶量高于GG基因型的牛。本发明通过优选该SNP的优势等位基因,能够逐代增加优势等位基因频率,提升种牛泌乳期总产奶量,选育泌乳期高产奶量性状的优良种牛,加快牛遗传改良进展从而有效提高种牛育种的经济效益。
Need to check novelty before this filing date? Find Prior Art