A stem cell introduction device

CN121243536BActive Publication Date: 2026-08-18THE FIFTH MEDICAL CENT OF CHINESE PLA GENERAL HOSPITAL
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Patent Information

Application Number
CN202511706659.3
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2025-11-20
Publication Date
2026-08-18
Estimated Expiration
2045-11-20

AI Technical Summary

Technical Problem

[0003]由于间充质干细胞静脉输注时的颗粒比较大,容易沉淀,为确保间充质干细胞在静脉输注过程中保持悬浮状态,需要在输注期间轻柔地摇晃药液,很不方便

Benefits of technology

该干细胞导入装置,通过设置的输导机构、导滑对接机构、拆装式驱动机构、膨胀式扰流机构和固定防脱机构,能够在使用时利用拆装式驱动机构驱动膨胀式扰流机构进行一定频率的周期性缓慢膨胀收缩实现对药液的扰流,从而确保间充质干细胞在静脉输注过程中保持悬浮状态。

✦ Generated by Eureka AI based on patent content.

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Abstract

The application relates to the technical field of stem cell introduction, and discloses a stem cell introduction device, which comprises a delivery mechanism, the top end of the delivery mechanism is provided with a guide sliding butt joint mechanism, the bottom end of the guide sliding butt joint mechanism is provided with a detachable driving mechanism, the top end of the guide sliding butt joint mechanism is provided with an inflation type turbulence mechanism, the surface of the guide sliding butt joint mechanism is provided with a fixed anti-falling mechanism, the delivery mechanism comprises a transfusion tube, the guide sliding butt joint mechanism comprises a mounting head and a lower threaded ring, and the mounting head is fixedly mounted at the top end of the transfusion tube. The stem cell introduction device is provided with the delivery mechanism, the guide sliding butt joint mechanism, the detachable driving mechanism, the inflation type turbulence mechanism and the fixed anti-falling mechanism, can drive the inflation type turbulence mechanism to periodically and slowly expand and contract at a certain frequency to realize turbulence of the liquid medicine when in use, and can ensure that mesenchymal stem cells remain in a suspended state during intravenous infusion.
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Description

Technical Field

[0001] This invention relates to the field of stem cell delivery technology, specifically a stem cell delivery device. Background Technology

[0002] Mesenchymal stem cell infusion is a regenerative medicine therapy. Its core involves separating and expanding mesenchymal stem cells derived from tissues such as bone marrow, adipose tissue, or umbilical cord in vitro, and then reinfusing them into the patient's body via intravenous injection. These stem cells are distributed throughout the body via blood circulation and promote the repair and functional recovery of damaged tissues through their unique immunomodulatory, anti-inflammatory properties and ability to secrete various beneficial cytokines. This allows them to be used to treat a variety of diseases, including neurological diseases, autoimmune diseases, and cardiovascular diseases.

[0003] Because mesenchymal stem cells are relatively large particles when administered intravenously, they are prone to sedimentation. To ensure that the mesenchymal stem cells remain suspended during intravenous infusion, the medication solution needs to be gently shaken during the infusion process, which is very inconvenient. Summary of the Invention

[0004] To address the shortcomings of existing technologies, this invention provides a stem cell delivery device that solves the problems mentioned in the background.

[0005] This invention provides the following technical solution: a stem cell delivery device, comprising: a delivery mechanism, a guide sliding docking mechanism at the top end of the delivery mechanism, a detachable drive mechanism at the bottom end of the guide sliding docking mechanism, an expansion-type turbulence-inducing mechanism at the top end of the guide sliding docking mechanism, and a fixing and anti-detachment mechanism on the surface of the guide sliding docking mechanism; the delivery mechanism includes an infusion tube; the guide sliding docking mechanism includes an installation head and a lower threaded ring; the installation head is fixedly installed at the top end of the infusion tube; the lower threaded ring is fixedly connected to the inner wall of the bottom end of the installation head; the detachable drive mechanism includes a screw head docking shell, a turbulence-inducing drive motor, and a threaded rod; the screw head docking... The shell is threaded inside the lower threaded ring. The turbulence drive motor is fixedly installed inside the shell where the screw head connects to the shell. The threaded rod is fixedly installed at the output end of the turbulence drive motor via a coupling. The expansion turbulence mechanism includes a plug-breaking guide head, a threaded cylinder, and a rubber expansion bladder. The plug-breaking guide head is located at the top of the mounting head. The threaded cylinder is fixedly inserted into the bottom of the plug-breaking guide head, and the inner wall of the threaded cylinder is threadedly connected to the surface of the threaded rod. The rubber expansion bladder is fixedly connected between the plug-breaking guide head and the mounting head, and nitrogen gas is filled between the plug-breaking guide head, the mounting head, and the rubber expansion bladder. The fixing and anti-detachment mechanism includes an extension ear, which is integrally set on the surface of the mounting head.

[0006] Preferably, the infusion mechanism further includes a constant pressure air inlet tube, an air filter, a drip chamber, a flow regulator, an extension hose, and a puncture needle. The constant pressure air inlet tube is fixedly installed on the surface of the mounting head, the air filter is fixedly installed at the free end of the constant pressure air inlet tube, the drip chamber is fixedly installed inside the infusion tube, the flow regulator is movably installed on the surface of the infusion tube, the extension hose is fixedly installed at the bottom end of the infusion tube, and the puncture needle is fixedly installed at the bottom end of the extension hose.

[0007] Preferably, the infusion mechanism further includes a support sleeve, a buffer sleeve, a strap, a male hook and loop fastener, and a female hook and loop fastener. The support sleeve is fixedly sleeved on the surface of the infusion tube, the buffer sleeve is fixedly sleeved on the surface of the support sleeve, the strap is integrally disposed on the surface of the buffer sleeve, and the male hook and loop fastener and the female hook and loop fastener are both fixedly installed on the surface of the strap.

[0008] Preferably, the guide sliding docking mechanism further includes an infusion channel, an air inlet channel, a stop ring, and a locking ring. The infusion channel and the air inlet channel are both opened through the surface of the mounting head, and the mounting head is fixedly connected to the infusion tube through the infusion channel, and the mounting head is fixedly connected to the constant pressure air inlet tube through the air inlet channel. The top of the infusion channel is lower than the top of the air inlet channel, and the stop ring and the locking ring are both integrally set on the surface of the mounting head.

[0009] Preferably, the guide sliding docking mechanism further includes support springs and flexible grooves. There are multiple support springs, and all of the multiple support springs are integrally set at the top of the mounting head. The roots of the multiple support springs have an outward elastic tendency. The rubber expansion and contraction bladder is located between the multiple support springs, and the flexible groove is embedded in the bottom end of the support spring.

[0010] Preferably, the guide sliding docking mechanism further includes a guide cylinder, a sliding seal ring, and a guide strip. The guide cylinder is fixedly inserted into the interior of the mounting head, the sliding seal ring is fixedly connected to the interior of the guide cylinder, and the guide strip is integrally disposed on the inner wall of the guide cylinder. The surface of the sliding seal ring is slidably connected to the surface of the threaded cylinder.

[0011] Preferably, the detachable drive mechanism further includes a battery, a control module, and an anti-slip sleeve. The battery and the control module are both fixedly installed inside the screw head mating shell, and both the battery and the control module are electrically connected to the turbulence drive motor. The anti-slip sleeve is fixedly fitted onto the surface of the screw head mating shell.

[0012] Preferably, the expansion-type turbulence mechanism further includes a plug-breaking cone and a card ring groove. The plug-breaking cone is integrally disposed at the top of the plug-breaking guide, and the card ring groove is embedded in the surface of the plug-breaking guide. The plug-breaking guide is engaged with multiple support springs through the card ring groove.

[0013] Preferably, the expansion-type turbulence mechanism further includes a limiting slide head and a guide groove. The limiting slide head is integrally disposed at one end of the threaded cylinder, and the surface of the limiting slide head is slidably connected to the inner wall of the guide cylinder. The guide groove is embedded in the surface of the limiting slide head, and the inner wall of the guide groove is slidably connected to the surface of the guide strip.

[0014] Preferably, the fixing and anti-detachment mechanism further includes a rotating frame and a rubber ring. There are two rotating frames, and both rotating frames are rotatably connected to the surface of the extension ear. The rubber ring is fixedly connected between the two rotating frames.

[0015] Compared with the prior art, the present invention has the following beneficial effects: This stem cell delivery device, through its delivery mechanism, guide and docking mechanism, detachable drive mechanism, expansion turbulence mechanism, and fixation and anti-detachment mechanism, enables the expansion turbulence mechanism to perform periodic, slow expansion and contraction at a certain frequency during use, thereby turbulenting the drug solution and ensuring that mesenchymal stem cells remain suspended during intravenous infusion.

[0016] This stem cell delivery device, through its infusion tube, constant pressure air inlet tube, air filter, drip chamber, flow regulator, extension tubing, puncture needle, support cannula, buffer sleeve, strap, male and female Velcro straps, can achieve basic infusion function through the infusion tube, while also using the support cannula and straps to fix the lower end of the infusion tube to the limb, preventing the puncture needle from being easily torn out when the infusion tube is dragged, thus improving safety.

[0017] This stem cell delivery device, through its installation head, threaded lower ring, infusion channel, air inlet channel, stop ring, locking ring, support spring, flexible groove, guide cylinder, sliding seal ring, and guide strip, provides connection and support for each mechanism during use. It also utilizes the support spring to protect and isolate the rubber expansion and contraction bladder during puncture, preventing jamming when puncture reaches the bladder. Furthermore, the support spring unfolds after the rubber expansion and contraction bladder enters the infusion bottle, thus avoiding obstruction of its expansion and contraction. When the installation head is withdrawn, the support spring retracts smoothly, thus providing protection and retracting to its original position upon withdrawal.

[0018] This stem cell delivery device, through its screw-head docking shell, turbulence drive motor, threaded rod, battery, control module, and anti-slip sleeve, can control the turbulence drive motor to provide forward and reverse rotation power source through the control module. This ensures that the rotation of the threaded rod drives the expansion and contraction of the rubber expansion and contraction bladder. At the same time, the screw-head docking shell facilitates the disassembly and assembly of the detachable drive mechanism, making it convenient for recycling when necessary.

[0019] This stem cell delivery device, with its designed components including a stopper-breaking guide, threaded cylinder, rubber expansion and contraction bladder, stopper-breaking cone, card ring groove, limiting slide head, and guide groove, allows the stopper to be punctured during use. The expansion and contraction of the rubber expansion and contraction bladder creates turbulence, ensuring that excessive shear force is not generated during turbulence. Simultaneously, the downward pressure of the stopper-breaking guide causes the rubber expansion and contraction bladder to expand, ensuring complementary space between the expansion and contraction of the rubber expansion and contraction bladder and the stopper-breaking cone. This avoids large pressure differential changes within the infusion bottle, thereby maximizing the integrity of the mesenchymal stem cells. Furthermore, the nitrogen filling inside the rubber expansion and contraction bladder ensures that no toxic gas leakage occurs in the event of device failure, guaranteeing safety.

[0020] This stem cell delivery device, with its extension ear, rotating frame, and rubber ring, ensures that the device is stably fixed to the surface of the infusion bottle during infusion, preventing it from easily falling off. Attached Figure Description

[0021] Figure 1 This is a schematic diagram of the structure of the present invention; Figure 2 This is a schematic diagram of the guide sliding docking mechanism of the present invention during insertion; Figure 3 This is a cross-sectional view of the supporting spring sheet when it is deployed according to the present invention; Figure 4 This is a schematic diagram of the connection structure between the guide sliding docking mechanism and the fixed anti-detachment mechanism of the present invention; Figure 5 This is a cross-sectional view of the location of the guide sliding docking mechanism of the present invention; Figure 6 This is a schematic diagram of the structure at the mounting head position of the present invention; Figure 7 This is a schematic diagram of the exploded structure at the location of the guide tube of the present invention; Figure 8 This is a cross-sectional view of the guide sliding docking mechanism of the present invention; Figure 9 This is a schematic diagram of the structure at the location of the support sleeve of the present invention.

[0022] In the picture: 101. Infusion tubing; 102. Constant pressure air inlet tubing; 103. Air filter; 104. Drip funnel; 105. Flow regulator; 106. Extension tubing; 107. Puncture needle; 108. Support sleeve; 109. Buffer sleeve; 110. Bandage; 111. Male Velcro strap; 112. Female Velcro strap; 201. Mounting head; 202. Lower threaded ring; 203. Infusion channel; 204. Air inlet channel; 205. Stop ring; 206. Locking ring; 207. Support spring; 208. 209. Flexible groove; 210. Guide cylinder; 211. Sliding seal ring; 302. Guide strip; 303. Screw head mating shell; 304. Turbulence drive motor; 305. Threaded rod; 306. Battery; 307. Control module; 408. Anti-slip sleeve; 409. Plug-breaking guide head; 400. Threaded cylinder; 401. Rubber expansion and contraction bladder; 402. Plug-breaking cone head; 403. Card ring groove; 404. Limiting slide head; 405. Guide groove; 506. Extension ear; 507. Rotating frame; 508. Rubber ring. Detailed Implementation

[0023] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0024] Please see Figure 1-9A stem cell delivery device includes: a delivery mechanism, a sliding docking mechanism at the top of the delivery mechanism, a detachable drive mechanism at the bottom of the sliding docking mechanism, an expansion-type turbulence-inducing mechanism at the top of the sliding docking mechanism, and a fixing and anti-detachment mechanism on the surface of the sliding docking mechanism. The delivery mechanism includes an infusion tube 101. The sliding docking mechanism includes an installation head 201 and a lower threaded ring 202. The installation head 201 is fixedly installed at the top of the infusion tube 101, and the lower threaded ring 202 is fixedly connected to the inner wall of the bottom of the installation head 201. The detachable drive mechanism includes a screw head docking shell 301, a turbulence-inducing drive motor 302, and a threaded rod 303. The screw head docking shell 301 is threadedly connected to the inside of the lower threaded ring 202. The turbulence-inducing drive motor 302 is fixedly installed inside the screw head docking shell 301. The threaded rod 303 is fixedly installed at the output end of the turbulence-inducing drive motor 302 via a coupling. The expansion-type turbulence-inducing mechanism includes... The device comprises a rupture guide 401, a threaded cylinder 402, and a rubber expansion and contraction bladder 403. The rupture guide 401 is located at the top of the mounting head 201. The threaded cylinder 402 is fixedly inserted into the bottom of the rupture guide 401, and the inner wall of the threaded cylinder 402 is threadedly connected to the surface of the threaded rod 303. The rubber expansion and contraction bladder 403 is fixedly connected between the rupture guide 401 and the mounting head 201, and nitrogen gas is filled between the rupture guide 401, the mounting head 201, and the rubber expansion and contraction bladder 403. The fixation and anti-dislodgement mechanism includes an extension ear 501, which is integrally set on the surface of the mounting head 201. Through the set delivery mechanism, guide sliding docking mechanism, disassembly and assembly drive mechanism, expansion turbulence mechanism, and fixation and anti-dislodgement mechanism, the expansion turbulence mechanism can be driven by the disassembly and assembly drive mechanism to perform periodic slow expansion and contraction at a certain frequency to turbulentize the drug solution, thereby ensuring that the mesenchymal stem cells remain suspended during intravenous infusion.

[0025] The infusion mechanism also includes a constant pressure air inlet pipe 102, an air filter 103, a drip chamber 104, a flow regulator 105, an extension hose 106, and a puncture needle 107. The constant pressure air inlet pipe 102 is fixedly installed on the surface of the mounting head 201, the air filter 103 is fixedly installed on the free end of the constant pressure air inlet pipe 102, the drip chamber 104 is fixedly installed inside the infusion tube 101, the flow regulator 105 is movably installed on the surface of the infusion tube 101, the extension hose 106 is fixedly installed at the bottom end of the infusion tube 101, and the puncture needle 107 is fixedly installed at the bottom end of the extension hose 106.

[0026] The infusion mechanism also includes a support sleeve 108, a buffer sleeve 109, a strap 110, a male hook and loop fastener 111, and a female hook and loop fastener 112. The support sleeve 108 is fixedly fitted onto the surface of the infusion tube 101, the buffer sleeve 109 is fixedly fitted onto the surface of the support sleeve 108, the strap 110 is integrally set on the surface of the buffer sleeve 109, and both the male hook and loop fastener 111 and the female hook and loop fastener 112 are fixedly installed on the surface of the strap 110. The infusion tube 101 and the constant pressure air inlet tube 102 are used to transmit the infusion. The air filter 103, drip chamber 104, flow regulator 105, extension tubing 106, puncture needle 107, support sleeve 108, buffer sleeve 109, strap 110, male Velcro 111, and female Velcro 112 enable basic intravenous infusion through the infusion tube 101. Furthermore, the support sleeve 108 and strap 110 secure the lower end of the infusion tube 101 to the limb, preventing the puncture needle 107 from easily tearing and dislodging when the infusion tube 101 is dragged, thus improving safety.

[0027] The guide sliding docking mechanism also includes an infusion channel 203, an air inlet channel 204, a stop ring 205, and a locking ring 206. The infusion channel 203 and the air inlet channel 204 are both opened through the surface of the mounting head 201. The mounting head 201 is fixedly connected to the infusion tube 101 through the infusion channel 203 and to the constant pressure air inlet tube 102 through the air inlet channel 204. The top of the infusion channel 203 is lower than the top of the air inlet channel 204. The stop ring 205 and the locking ring 206 are both integrally set on the surface of the mounting head 201.

[0028] The guide sliding docking mechanism also includes a support spring 207 and a flexible groove 208. There are multiple support springs 207, and all of the multiple support springs 207 are integrally set at the top of the mounting head 201. The roots of the multiple support springs 207 all have an outward elastic tendency. The rubber expansion and contraction bladder 403 is located between the multiple support springs 207. The flexible groove 208 is embedded in the bottom end of the support spring 207.

[0029] The guide sliding docking mechanism also includes a guide cylinder 209, a sliding seal ring 210, and a guide strip 211. The guide cylinder 209 is fixedly inserted into the interior of the mounting head 201, the sliding seal ring 210 is fixedly connected to the interior of the guide cylinder 209, and the guide strip 211 is integrally set on the inner wall of the guide cylinder 209. The surface of the sliding seal ring 210 is slidably connected to the surface of the threaded cylinder 402. The mechanism is connected via the mounting head 201, the lower threaded ring 202, the infusion channel 203, the air inlet channel 204, the stop ring 205, the locking ring 206, the support spring 207, the flexible groove 208, and the guide... The positioning sleeve 209, sliding seal ring 210, and guide strip 211 provide connection and support for various mechanisms during use. They also utilize the support spring 207 to protect and isolate the rubber expansion and contraction bladder 403 during puncture, preventing jamming when puncturing the rubber expansion and contraction bladder 403. Furthermore, the support spring 207 unfolds after the rubber expansion and contraction bladder 403 enters the infusion bottle, thus avoiding obstruction to the expansion and contraction of the rubber expansion and contraction bladder 403. When the installation head 201 is withdrawn, the support spring 207 can be smoothly contracted, thus providing protection and retracting to its original position upon withdrawal.

[0030] The detachable drive mechanism also includes a battery 304, a control module 305, and an anti-slip sleeve 306. The battery 304 and the control module 305 are both fixedly installed inside the screw head docking shell 301, and the battery 304 and the control module 305 are both electrically connected to the turbulence drive motor 302. The anti-slip sleeve 306 is fixedly sleeved on the surface of the screw head docking shell 301.

[0031] The expansion-type turbulence mechanism also includes a plug-breaking cone 404 and a card ring groove 405. The plug-breaking cone 404 is integrally set at the top of the plug-breaking guide 401, and the card ring groove 405 is embedded in the surface of the plug-breaking guide 401. The plug-breaking guide 401 is engaged with multiple support springs 207 through the card ring groove 405. Through the provided screw head docking shell 301, turbulence drive motor 302, threaded rod 303, battery 304, control module 305 and anti-slip sleeve 306, the control module 305 can control the turbulence drive motor 302 to provide forward and reverse rotation power source, ensuring that the rotation of the threaded rod 303 drives the expansion and contraction of the rubber expansion and contraction bladder 403. At the same time, the screw head docking shell 301 facilitates the disassembly and assembly of the detachable drive mechanism, making it convenient for the detachable drive mechanism to be recycled when necessary.

[0032] The expansion-type turbulence mechanism also includes a limiting slide head 406 and a guide groove 407. The limiting slide head 406 is integrally disposed at one end of the threaded cylinder 402, and the surface of the limiting slide head 406 is slidably connected to the inner wall of the guide cylinder 209. The guide groove 407 is embedded in the surface of the limiting slide head 406, and the inner wall of the guide groove 407 is slidably connected to the surface of the guide strip 211. Through the provided plug-breaking guide head 401, threaded cylinder 402, rubber expansion and contraction bladder 403, plug-breaking cone head 404, card ring groove 405, limiting slide head 406, and guide groove 407, the expansion-type turbulence mechanism can utilize the breaking... The stopper cone 404 auxiliary device punctures the bottle stopper, and the expansion and contraction of the rubber expansion and contraction bladder 403 achieves turbulence, ensuring that no large shear force is generated during turbulence. At the same time, the downward pressure of the stopper-breaking guide 401 causes the rubber expansion and contraction bladder 403 to expand, ensuring that the expansion and contraction of the rubber expansion and contraction bladder 403 and the stopper-breaking cone 404 complement each other in terms of space margin, avoiding large pressure difference changes inside the infusion bottle, thereby maximizing the integrity of mesenchymal stem cells. In addition, the nitrogen filling inside the rubber expansion and contraction bladder 403 ensures that no toxic gas leakage will occur in the event of device failure, ensuring safety.

[0033] The fixing and anti-detachment mechanism also includes a rotating frame 502 and a rubber ring 503. There are two rotating frames 502, and both rotating frames 502 are rotatably connected to the surface of the extension ear 501. The rubber ring 503 is fixedly connected between the two rotating frames 502. Through the extension ear 501, rotating frame 502 and rubber ring 503, the device can be stably fixed to the surface of the infusion bottle during infusion, preventing the device from easily falling off.

[0034] Working principle: In use, the control module 305 controls the start of the turbulence drive motor 302, which drives the threaded rod 303 to rotate slowly to ensure that it is screwed into the threaded cylinder 402 and then closed. Then, the screw head is twisted to connect the housing 301 and install it into the lower threaded ring 202. The stopper-breaking guide 401 and the mounting head 201 are inserted into the infusion bottle through the stopper-breaking cone 404. Due to the wrapping of the support spring 207, the rubber expansion bladder 403 can be smoothly inserted until the locking ring 206 passes through the bottle stopper. Then, the rotating frame 502 is rotated to fix the rubber ring 503 in the recess of the infusion bottle mouth. Then, the turbulence drive motor 302 is started by the control module 305. The turbulence drive motor 302 drives the threaded rod 303 to rotate slowly. When the threaded rod 303 rotates, it pushes the threaded cylinder 402, so that the stopper-breaking guide 401 overcomes the elastic tension of the rubber expansion bladder 403 and extends upward, thereby causing the support spring 207 to come out from the inside of the locking ring groove 405. After the support spring 207 comes out, it opens due to its own elasticity, thereby exposing the rubber expansion bladder 403. Then, the medical staff manually and gently shakes the infusion bottle once to remove any sediment. Then, the control module 305 controls the turbulence drive motor 302 to periodically and slowly rotate forward and backward. When the turbulence drive motor 302 rotates, it pushes the threaded cylinder 402 to periodically extend and retract along the guide strip 211, thereby causing the stopper-breaking guide head 401 to periodically rise and fall. When the stopper-breaking guide head 401 descends, it compresses nitrogen gas, causing the rubber expansion and contraction bladder 403 to slowly expand. When the stopper-breaking guide head 401 rises, it creates negative pressure, pulling the rubber expansion and contraction bladder 403 to slowly contract. Thus, the expansion and contraction of the rubber expansion and contraction bladder 403 achieves turbulence and prevents the medication from settling. At the same time, when the stopper cone head 404 contracts, the space inside the medication is filled by the expansion of the rubber expansion and contraction bladder 403. When the stopper cone head 404 extends, the space inside the medication is again filled by the contraction of the rubber expansion and contraction bladder 403, thus ensuring the internal pressure balance of the medication and preventing it from disturbing the infusion tube 101. During fluid replacement, the control module 305 controls the turbulence drive motor 302 to start, causing the rubber expansion and contraction bladder 403 to reach a contracted state. Then, the rotating frame 502 is deployed to remove the rubber ring 503 from the recess. Then, the installation head 201 and the stopper-breaking guide head 401 are slowly pulled out. During the pull-out, the support spring 207 is squeezed and contracted by the bottle stopper, causing its end to enter one side of the card ring groove 405. Then, the threaded rod 303 is activated to cause the threaded cylinder 402 to contract, thereby retracting the support spring 207 into the card ring groove 405. Then, the installation head 201 is pulled out, and the stopper-breaking cone head 404 is inserted into the new infusion bottle and inserted and fixed according to the initial state, thereby realizing fluid replacement. During intravenous infusion, the bandage 110 is placed on the patient's limb receiving the infusion and loosely secured with male Velcro 111 and female Velcro 112. When securing, care should be taken to avoid compressing the limb, so as to prevent the infusion tube 101 from tearing and the puncture needle 107 from coming out when it is pulled.

[0035] Although embodiments of the invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A stem cell delivery device, characterized in that, include: The conveying mechanism has a guide sliding docking mechanism at its top end, a detachable drive mechanism at its bottom end, an expansion-type turbulence mechanism at its top end, and a fixing anti-detachment mechanism on its surface. The delivery mechanism includes an infusion tube (101), and the guide sliding docking mechanism includes an installation head (201) and a lower threaded ring (202). The installation head (201) is fixedly installed at the top of the infusion tube (101), and the lower threaded ring (202) is fixedly connected to the inner wall of the bottom end of the installation head (201). The detachable drive mechanism includes a screw head docking shell (301), a turbulence drive motor (302), and a threaded rod (303). The screw head docking shell (301) is threadedly connected to the inside of the lower threaded ring (202), the turbulence drive motor (302) is fixedly installed inside the screw head docking shell (301), and the threaded rod (303) is fixedly installed at the output end of the turbulence drive motor (302) via a coupling. The expansion-type turbulence mechanism includes a plugging guide (401), a threaded cylinder (402), and a rubber expansion bladder (403). The plugging guide (401) is located at the top of the mounting head (201). The threaded cylinder (402) is fixedly inserted into the bottom of the plugging guide (401), and the inner wall of the threaded cylinder (402) is threadedly connected to the surface of the threaded rod (303). The rubber expansion bladder (403) is fixedly connected between the plugging guide (401) and the mounting head (201), and nitrogen gas is filled between the plugging guide (401), the mounting head (201), and the rubber expansion bladder (403). The fixing and anti-detachment mechanism includes an extension ear (501), which is integrally set on the surface of the mounting head (201). The guide sliding docking mechanism also includes a support spring (207) and a flexible groove (208). There are multiple support springs (207), and all multiple support springs (207) are integrally set at the top of the mounting head (201). The roots of the multiple support springs (207) all have an outward elastic tendency. The rubber expansion and contraction bladder (403) is located between the multiple support springs (207). The flexible groove (208) is embedded in the bottom end of the support spring (207). The expansion-type turbulence mechanism also includes a plug-breaking cone (404) and a card ring groove (405). The plug-breaking cone (404) is integrally disposed at the top of the plug-breaking guide (401). The card ring groove (405) is embedded in the surface of the plug-breaking guide (401), and the plug-breaking guide (401) is engaged with multiple support springs (207) through the card ring groove (405). The expansion-type turbulence mechanism also includes a limiting slide head (406) and a guide groove (407). The limiting slide head (406) is integrally disposed at one end of the threaded cylinder (402), and the surface of the limiting slide head (406) is slidably connected to the inner wall of the guide cylinder (209). The guide groove (407) is embedded in the surface of the limiting slide head (406), and the inner wall of the guide groove (407) is slidably connected to the surface of the guide strip (211).

2. The stem cell delivery device according to claim 1, characterized in that, The delivery mechanism also includes a constant pressure air inlet tube (102), an air filter (103), a drip chamber (104), a flow regulator (105), an extension hose (106), and a puncture needle (107). The constant pressure air inlet tube (102) is fixedly installed on the surface of the mounting head (201). The air filter (103) is fixedly installed at the free end of the constant pressure air inlet tube (102). The drip chamber (104) is fixedly installed inside the infusion tube (101). The flow regulator (105) is movably installed on the surface of the infusion tube (101). The extension hose (106) is fixedly installed at the bottom end of the infusion tube (101). The puncture needle (107) is fixedly installed at the bottom end of the extension hose (106).

3. The stem cell delivery device according to claim 2, characterized in that, The delivery mechanism also includes a support sleeve (108), a buffer sleeve (109), a strap (110), a male Velcro strap (111), and a female Velcro strap (112). The support sleeve (108) is fixedly sleeved on the surface of the infusion tube (101), the buffer sleeve (109) is fixedly sleeved on the surface of the support sleeve (108), the strap (110) is integrally disposed on the surface of the buffer sleeve (109), and the male Velcro strap (111) and the female Velcro strap (112) are both fixedly installed on the surface of the strap (110).

4. The stem cell delivery device according to claim 1, characterized in that, The guide sliding docking mechanism also includes an infusion channel (203), an air inlet channel (204), a stop ring (205), and a locking ring (206). The infusion channel (203) and the air inlet channel (204) are both opened through the surface of the mounting head (201). The mounting head (201) is fixedly connected to the infusion tube (101) through the infusion channel (203) and the mounting head (201) is fixedly connected to the constant pressure air inlet tube (102) through the air inlet channel (204). The top of the infusion channel (203) is lower than the top of the air inlet channel (204). The stop ring (205) and the locking ring (206) are both integrally set on the surface of the mounting head (201).

5. The stem cell delivery device according to claim 1, characterized in that, The guide sliding docking mechanism also includes a guide cylinder (209), a sliding seal ring (210), and a guide strip (211). The guide cylinder (209) is fixedly inserted into the interior of the mounting head (201). The sliding seal ring (210) is fixedly connected to the interior of the guide cylinder (209). The guide strip (211) is integrally set on the inner wall of the guide cylinder (209), and the surface of the sliding seal ring (210) is slidably connected to the surface of the threaded cylinder (402).

6. The stem cell delivery device according to claim 1, characterized in that, The detachable drive mechanism also includes a battery (304), a control module (305), and an anti-slip sleeve (306). The battery (304) and the control module (305) are both fixedly installed inside the screw head docking shell (301), and the battery (304) and the control module (305) are both electrically connected to the turbulence drive motor (302). The anti-slip sleeve (306) is fixedly sleeved on the surface of the screw head docking shell (301).

7. The stem cell delivery device according to claim 1, characterized in that, The fixing and anti-detachment mechanism also includes a rotating frame (502) and a rubber ring (503). There are two rotating frames (502), and both rotating frames (502) are rotatably connected to the surface of the extension ear (501). The rubber ring (503) is fixedly connected between the two rotating frames (502).

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