A microsphere preparation system

Abstract

The application discloses a microsphere preparation system, which comprises a raw material supply module, a microsphere preparation module, a patrol monitoring module and a screening and distributing module; the output end of the raw material supply module is connected with the input end of the microsphere preparation module; the patrol monitoring module is movably arranged on one side of the microsphere preparation module and is used for monitoring the microsphere solution prepared by the microsphere preparation module; the screening and distributing module comprises a finished product collecting bin, a waste product collecting bin and a driving traction part; the finished product collecting bin and the waste product collecting bin are both arranged below a hose connected with the output end of the microsphere preparation module; the driving traction part is connected with the hose and is used for selectively directing the discharge opening of the hose to the finished product collecting bin or the waste product collecting bin; the microsphere preparation module, the patrol monitoring module and the driving traction part are all connected with the same control terminal signal. Through the above arrangement, stable raw material supply, rapid, accurate and automatic screening and switching of the finished product and the waste product in the microsphere preparation process are realized, and the production quality and the production rate are improved.

Description

Technical Field

[0001] This invention relates to the fields of food, pharmaceutical and cosmetic production, and in particular to a microsphere preparation system. Background Technology

[0002] In the food, pharmaceutical, and cosmetic manufacturing industries, microspheres are widely used for active ingredient encapsulation, sustained-release carriers, and texture improvement due to their unique particle size distribution, surface properties, and encapsulation capabilities. The quality of their preparation directly affects the efficacy and safety of the final product. Therefore, particle size uniformity, purity, and production efficiency during microsphere preparation have become core indicators of industry focus.

[0003] In existing technologies, the separation of finished and waste products after microsphere preparation largely relies on manual operation. Operators must visually inspect or perform post-processing sampling to determine the quality of the microspheres, then manually switch collection containers to direct qualified finished products into a finished product collection device and unqualified waste products into a waste collection device. This method is not only inefficient but also suffers from significant delays and subjectivity.

[0004] Specifically, due to the slow response speed of manual judgment and switching, during the continuous production of microspheres, there is a tendency for switching to be delayed, resulting in unqualified waste products being mixed into the finished products, affecting product quality.

[0005] Furthermore, the accuracy of manual operation is greatly affected by factors such as the operator's experience and condition, which may lead to misjudgment or misoperation, treating finished products as waste, resulting in waste of raw materials and increased production costs, or collecting waste products as finished products, reducing the qualification rate of the final product.

[0006] Furthermore, when the microsphere preparation system has multiple preparation units to improve production efficiency, the traditional manual screening and switching method is difficult to achieve synchronous and precise control of multiple units. The collection of finished products and waste products in each unit is prone to confusion, which further restricts the stability of production efficiency and product quality.

[0007] Therefore, a microsphere preparation system is needed to solve the above problems. Summary of the Invention

[0008] The purpose of this invention is to provide a microsphere preparation system that enables rapid, precise, and automated screening and switching between finished and waste products during the microsphere preparation process, thereby improving production quality and production rate.

[0009] To solve the above-mentioned technical problems, the present invention provides a microsphere preparation system, comprising: a raw material feeding module, a microsphere preparation module, an inspection and monitoring module, and a screening and dispensing module; The output end of the raw material feeding module is connected to the input end of the microsphere preparation module. The raw material feeding module is used to buffer the raw material liquid required for microsphere preparation and to deliver the buffered raw material liquid at constant pressure after diversion. The microsphere preparation module is used to receive the raw material liquid and prepare a microsphere solution. The inspection and monitoring module is movably mounted on one side of the microsphere preparation module and is used to monitor the microsphere solution prepared by the microsphere preparation module. The screening and sorting module includes a finished product collection bin, a waste product collection bin, and a drive traction component; Both the finished product collection bin and the waste product collection bin are located below the hose connected to the output end of the microsphere preparation module; The connection between the drive traction component and the hose is used to control the outlet of the hose to selectively point to the finished product collection bin or the waste collection bin; The raw material feeding module, the microsphere preparation module, the inspection and monitoring module, and the drive traction component are all connected to the same control terminal. The control terminal is used to coordinate the execution of each process step and achieve fully automated control based on sensor signals and preset process parameters.

[0010] Furthermore, the raw material supply module includes an oil phase conveying pipeline and an aqueous phase conveying pipeline; The oil phase delivery pipeline and the aqueous phase delivery pipeline are respectively connected to the two input ends of the microsphere preparation module, and delivery pumps are provided on the oil phase delivery pipeline and the aqueous phase delivery pipeline.

[0011] Furthermore, the microsphere preparation module includes an oil phase pressure control tank, an aqueous phase flow rate control tank, and a piezoelectric valve microsphere preparation unit; One end of the oil phase pressure control tank is connected to the oil phase delivery pipeline, and the other end is connected to the piezoelectric valve microsphere preparation unit; One end of the aqueous phase flow rate control tank is connected to the aqueous phase delivery pipeline, and the other end is connected to the piezoelectric valve microsphere preparation unit; The piezoelectric valve microsphere preparation unit is used to receive the raw material liquid and prepare a microsphere solution; The output end of the piezoelectric valve microsphere preparation unit is connected to the flexible tube.

[0012] Furthermore, the piezoelectric valve microsphere preparation unit has an oil phase flow rate controller and a temperature controller, which are used to control the flow rate of the oil phase liquid and the temperature during the preparation of the microsphere solution, respectively.

[0013] Furthermore, an observation chamber is provided between the piezoelectric valve microsphere preparation unit and the hose; The observation chamber has a transparent window, and the transparent window faces the inspection and monitoring module.

[0014] Furthermore, the piezoelectric valve microsphere preparation unit is provided in multiple sets, and is arranged in rows at equal intervals along the moving direction of the inspection and monitoring module.

[0015] Furthermore, the inspection and monitoring module includes a linear guide rail and a visual monitoring module; The linear guide rail is disposed on one side of the microsphere preparation module, and the visual monitoring module is slidably mounted on the linear guide rail via a drive mechanism; The visual monitoring module is used to acquire the contour parameters, particle size parameters, and surface depression parameters of the microspheres. The control terminal determines whether the microspheres are abnormal based on the microsphere parameters provided by the visual monitoring module and the preset standard parameters.

[0016] Furthermore, both the finished product collection bin and the waste product collection bin have an inclined inner cavity bottom wall.

[0017] Furthermore, the finished product collection bin is connected to a microsphere cylinder via a pipeline.

[0018] Furthermore, the driving traction component is configured as an electric telescopic rod; The finished product collection bin and the waste product collection bin are arranged parallel to each other along the extension and retraction direction of the electric telescopic rod.

[0019] Compared with the prior art, the present invention has at least the following beneficial effects: By setting up a raw material feeding module, a microsphere preparation module, an inspection and monitoring module, and a screening and dispensing module, and connecting the drive traction components in the microsphere preparation module, inspection and monitoring module, and screening and dispensing module to the same control terminal signal, when the inspection and monitoring module monitors the microsphere solution prepared by the microsphere preparation module, the control terminal can control the drive traction component to drive the hose according to the monitoring results. This enables the hose outlet to selectively point between the finished product collection bin and the waste product collection bin, thereby automating the screening and switching between finished and waste materials, reducing manual intervention, improving the timeliness and accuracy of screening and switching, ensuring product quality, and improving overall preparation efficiency. Attached Figure Description

[0020] Figure 1 This is a schematic diagram of the microsphere preparation system in one embodiment of the present invention; Figure 2 This is a partial structural diagram of the piezoelectric valve microsphere preparation unit in a microsphere preparation system according to an embodiment of the present invention; Figure 3 This is a schematic diagram of the driving and traction component of the microsphere preparation system in one embodiment of the present invention; Figure 4This is a schematic diagram of the inspection and monitoring module of the microsphere preparation system in one embodiment of the present invention; Figure 5 This is a schematic diagram of the finished product collection chamber of a microsphere preparation system in one embodiment of the present invention.

[0021] Reference numerals: 1. Raw material feeding module; 11. Oil phase conveying pipeline; 12. Aqueous phase conveying pipeline; 13. Conveying pump; 2. Microsphere preparation module; 21. Oil phase pressure control tank; 22. Aqueous phase flow rate control tank; 23. Piezoelectric valve microsphere preparation unit; 231. Oil phase flow rate controller; 232. Temperature controller; 3. Inspection and monitoring module; 31. Linear guide rail; 32. Visual monitoring module; 4. Screening and sorting module; 41. Finished product collection bin; 42. Waste collection bin; 43. Drive traction component; 5. Hoses; 6. Observation bin; 61. Transparent window; 7. Microsphere barrel. Detailed Implementation

[0022] The microsphere preparation system of the present invention will now be described in more detail with reference to the schematic diagrams, which illustrate preferred embodiments of the invention. It should be understood that those skilled in the art can modify the invention described herein while still achieving its advantageous effects. Therefore, the following description should be understood as being of general knowledge to those skilled in the art and is not intended to limit the invention.

[0023] Furthermore, based on the teachings of this specification, those skilled in the art can form new technical solutions through cross-combination of different implementation methods without creating technical contradictions. Such variations should all be considered to fall within the protection scope of this patent.

[0024] The invention is described more specifically by way of example in the following paragraphs with reference to the accompanying drawings. The advantages and features of the invention will become clearer from the following description. It should be noted that the drawings are in a very simplified form and use non-precise proportions, and are only used to facilitate and clarify the illustration of the embodiments of the invention.

[0025] like Figures 1 to 5 As shown in the figure, an embodiment of the present invention proposes a microsphere preparation system, including a raw material feeding module 1, a microsphere preparation module 2, an inspection and monitoring module 3, and a screening and sorting module 4.

[0026] The output end of the raw material supply module 1 is connected to the input end of the microsphere preparation module 2. The raw material supply module is used to buffer the raw material liquid required for microsphere preparation and to deliver the buffered raw material liquid at constant pressure after diversion. The microsphere preparation module 2 is used to receive the raw material liquid and prepare microsphere solution.

[0027] The inspection and monitoring module 3 is movably disposed on one side of the microsphere preparation module 2 and is used to monitor the microsphere solution prepared by the microsphere preparation module 2, that is, to monitor whether the prepared microsphere solution is abnormal.

[0028] The screening and sorting module 4 includes a finished product collection bin 41, a waste product collection bin 42, and a drive traction component 43.

[0029] The finished product collection chamber 41 and the waste product collection chamber 42 are both located below the hose 5 connected to the output end of the microsphere preparation module 2, and are used to collect qualified microsphere solutions and unqualified microsphere solutions respectively.

[0030] The connection between the drive traction component 43 and the hose 5 is used to control the outlet of the hose 5 to selectively point to the finished product collection bin 41 or the waste collection bin 42. By controlling the pointing position of the hose 5 through the drive traction component 43, the function of classified collection can be achieved.

[0031] It should be noted that the microsphere preparation module 2, the inspection and monitoring module 3, and the drive traction component 43 are connected to the same control terminal signal. That is, the control terminal can control the drive traction component 43 to operate based on the information obtained by the inspection and monitoring module 3, thereby completing the collection of qualified and unqualified microsphere solutions.

[0032] Preferably, the driving traction component 43 is configured as an electric telescopic rod, and the finished product collection bin 41 and the waste product collection bin 42 are arranged parallel to each other along the extension and retraction direction of the electric telescopic rod, so as to facilitate the control of the discharge end of the hose 5 to switch between the finished product collection bin 41 and the waste product collection bin 42.

[0033] This device comprises a raw material feeding module 1, a microsphere preparation module 2, an inspection and monitoring module 3, and a screening and dispensing module 4. The drive traction component 43 in these modules is connected to the same control terminal. When the inspection and monitoring module 3 monitors the microsphere solution prepared by the microsphere preparation module 2, the control terminal can control the drive traction component 43 to move the flexible tube 5 based on the monitoring results. This allows the outlet of the flexible tube 5 to selectively point between the finished product collection bin 41 and the waste product collection bin 42, thereby automating the screening and switching between finished and waste materials. This reduces manual intervention, improves the timeliness and accuracy of screening and switching, ensures product quality, and enhances overall preparation efficiency.

[0034] In one embodiment, the raw material supply module 1 includes an oil phase conveying pipeline 11 and an aqueous phase conveying pipeline 12.

[0035] Specifically, the oil phase delivery pipeline 11 and the aqueous phase delivery pipeline 12 are respectively connected to the two input ends of the microsphere preparation module 2, and a delivery pump 13 is provided on the oil phase delivery pipeline 11 and the aqueous phase delivery pipeline 12.

[0036] In a further embodiment, the microsphere preparation module 2 includes an oil phase pressure control tank 21, an aqueous phase flow rate control tank 22, and a piezoelectric valve microsphere preparation unit 23.

[0037] One end of the oil phase pressure control tank 21 is connected to the oil phase delivery pipeline 11, and the other end is connected to the piezoelectric valve microsphere preparation unit 23.

[0038] One end of the aqueous phase flow rate control tank 22 is connected to the aqueous phase delivery pipeline 12, and the other end is connected to the piezoelectric valve microsphere preparation unit 23.

[0039] In this embodiment, the microsphere preparation module 2 controls the oil phase pressure and aqueous phase flow rate before microsphere preparation, while the raw material feeding module 1 feeds the raw materials for the microspheres at constant pressure, ensuring good roundness, uniformity, and stability of the finished microspheres during continuous production. This is because constant pressure feeding indirectly ensures a constant raw material flow rate by stabilizing the system pressure. Especially when the material viscosity is high or the resistance of the conveying pipeline changes (such as pipeline blockage or temperature fluctuations), it automatically compensates for pressure fluctuations, avoiding a widening of the particle size distribution of the finished microspheres due to sudden changes in flow rate. For example, in the emulsification-solvent evaporation method, constant pressure conveying of the oil phase raw material can ensure uniform droplet size.

[0040] Furthermore, constant pressure feeding reduces the turbulence effect of materials in the pipeline through smooth pressure output, avoids the damage to the molecular structure of raw materials caused by high shear force due to sudden pressure changes, and the constant pressure environment can maintain the thermodynamic stability of the raw material system, prevent raw material precipitation or phase separation during microsphere preparation, and ensure the integrity of the core structure.

[0041] The piezoelectric valve microsphere preparation unit 23 is used to receive raw material liquid and prepare microsphere solution, that is, to use the high frequency vibration (such as hundreds to thousands of hertz) of the piezoelectric valve to cut the raw material liquid into uniform micro droplets, and the droplets solidify under physical or chemical action to form microsphere solution.

[0042] The output end of the piezoelectric valve microsphere preparation unit 23 is connected to the hose 5 to complete the output of the microsphere solution.

[0043] In this embodiment, the piezoelectric valve microsphere preparation unit 23 includes an oil phase flow rate controller 231 and a temperature controller 232, which are used to control the flow rate of the oil phase liquid and the temperature during microsphere solution preparation, respectively. This allows the monitoring module 3 to adjust the parameters of the oil phase pressure control tank 21, the water phase flow rate control tank 22, the oil phase flow rate controller 231, and the temperature controller 232 via the control terminal when an abnormality is detected in the microspheres, thus achieving a self-checking and repair function.

[0044] In a specific example, when the inspection and monitoring module 3 detects an abnormality in the microsphere solution, the control terminal controls the drive traction component 43 to operate, so that the hose 5 points towards the waste collection bin 42. Then, the microsphere preparation module 2 is controlled to perform a self-check (such as adjusting parameters, including the flow rate of the raw material liquid, the output pressure of the raw material liquid, and the preparation temperature). If the self-check can be repaired, the drive traction component 43 is controlled to point the hose 5 back towards the finished product collection bin 41. If the self-check cannot be repaired, the corresponding microsphere preparation module 2 is controlled to stop operating to avoid waste of raw materials.

[0045] It should be noted that the control terminal stores the correspondence between the microsphere anomaly type and the target values ​​of parameters such as oil phase pressure, oil phase flow rate, water phase flow rate, and temperature. The control terminal is used to control the oil phase pressure control tank 21, oil phase flow rate controller 231, water phase flow rate control tank 22, and temperature controller 232 to adjust each parameter according to the correspondence and the microsphere anomaly signal monitored by the inspection and monitoring module 3.

[0046] Among them, abnormal microsphere conditions mainly include three situations: microspheres with excessively large particle size, microspheres with excessively small particle size, and microspheres with irregular shapes.

[0047] Therefore, the parameter adjustments for the control terminal under the above three abnormal situations are explained here, as follows: When the inspection and monitoring module 3 detects that the microspheres have excessively large particle size, the control terminal controls the oil phase pressure control tank 21 to reduce the oil phase pressure, the oil phase flow rate controller 231 to reduce the oil phase flow rate, the water phase flow rate control tank 22 to increase the water phase flow rate, and the temperature controller 232 to appropriately increase the temperature according to the corresponding relationship.

[0048] When the microsphere particle size is detected to be too small, the control terminal controls the oil phase pressure control tank 21 to increase the oil phase pressure, the oil phase flow rate controller 231 to increase the oil phase flow rate, the water phase flow rate control tank 22 to decrease the water phase flow rate, and the temperature controller 232 to appropriately lower the temperature.

[0049] When irregularities in the shape of the microspheres are detected, the control terminal controls the oil phase pressure control tank 21, the oil phase flow rate controller 231, and the water phase flow rate control tank 22 to adjust the oil phase pressure, oil phase flow rate, and water phase flow rate to a more suitable state, while controlling the temperature controller 232 to stabilize the temperature within a specific suitable range.

[0050] In other words, this device achieves automatic parameter adjustment and completes self-testing and repair functions through the above control.

[0051] In a further embodiment, in order to facilitate the inspection and monitoring module 3 in monitoring the microsphere solution for abnormalities, an observation chamber 6 is also provided to expose the morphology of the microsphere solution after preparation, so that the inspection and monitoring module 3 can identify the corresponding information (such as monitoring microsphere morphology or particle size data).

[0052] Specifically, an observation chamber 6 is provided between the piezoelectric valve microsphere preparation unit 23 and the hose 5.

[0053] The observation chamber 6 has a transparent window 61, and the transparent window 61 faces the inspection and monitoring module 3.

[0054] In a further embodiment, to meet the needs of large-scale microsphere production, multiple sets of the piezoelectric valve microsphere preparation unit 23 are provided and are arranged in rows at equal intervals along the moving direction of the inspection and monitoring module 3, so that the inspection and monitoring module 3 can monitor the microsphere solution prepared by each set of piezoelectric valve microsphere preparation unit 23 during the movement process.

[0055] In this embodiment, the inspection and monitoring module 3 includes a linear guide rail 31 and a visual monitoring module 32.

[0056] The linear guide rail 31 is disposed on one side of the microsphere preparation module 2, and the visual monitoring module 32 is slidably mounted on the linear guide rail 31 via a drive mechanism. The drive mechanism can be configured as a drive device consisting of a lead screw and a motor, or it can be configured as other transmission structures, such as the tracked transmission structure shown in this embodiment, without further limitation.

[0057] It should be noted that the visual monitoring module 32 is an industrial camera in the prior art. When it moves along the linear guide rail 31 through the drive mechanism, it can take pictures of the microspheres at a preset frequency to obtain parameter information such as the outline, particle size and surface of the microspheres. Then, the data is uploaded to the control terminal, which compares it with the built-in database to determine whether there is any abnormality in the microsphere solution prepared by the piezoelectric valve microsphere preparation unit 23.

[0058] Specifically, an industrial camera moves and captures images of the microspheres prepared in each piezoelectric valve microsphere preparation unit 23. Image recognition technology is used to extract the microspheres' contour parameters (e.g., whether the contour is a standard circle), particle size parameters (e.g., an average particle size of 500 μm), and surface parameters (e.g., whether there are obvious depressions or protrusions on the surface). This data is then uploaded to the control terminal. Finally, the control terminal compares the uploaded microsphere parameters with the standard parameters in the database and determines whether any anomalies have occurred.

[0059] In a specific example, the standard parameter range includes a standard circular profile, a particle size between 400-500 μm, and a smooth surface without obvious defects.

[0060] The anomaly detection method includes the following steps: If the average particle size of the extracted microspheres is found to be 600 μm, which exceeds the standard range of 400-500 μm, it is judged that the microsphere solution has an abnormality of excessive particle size. When the average particle size of the microspheres is found to be 300 μm, which is less than the lower limit of the standard range, it is judged that there is an abnormality of excessively small particle size. When the microspheres are found to have an obvious elliptical or irregular polygonal outline and multiple depressions with a depth of more than 100 μm on the surface, it is determined that there is an abnormality in the shape.

[0061] It should be noted that when the judgment result is that the microspheres are abnormal, the control terminal first controls the drive traction component 32 to orient the hose 5 connected to the corresponding piezoelectric valve microsphere preparation module 23 toward the waste collection bin 42. Then, it controls the oil phase pressure control tank 21, oil phase flow rate controller 231, water phase flow rate control tank 22 and temperature controller 232 to adjust the parameters for self-testing and repair. If the repair is successful, the hose 5 is reoriented toward the finished product collection bin 41. If the repair is unsuccessful, the piezoelectric valve microsphere preparation module 23 is shut down to avoid waste of raw materials.

[0062] In a specific example, to better meet the functions of microsphere image capture and parameter information acquisition, the industrial camera is set to a GV-H1000 series industrial camera. This series of cameras has high resolution and can clearly capture microsphere details, thus meeting the need for accurate extraction of parameters such as microsphere contour, particle size, and surface area.

[0063] In a further embodiment, to facilitate the rapid discharge of qualified and unqualified microsphere solutions into a designated storage device, the finished product collection bin 41 and the waste collection bin 42 are further defined.

[0064] Specifically, both the finished product collection bin 41 and the waste collection bin 42 have an inclined inner cavity bottom wall.

[0065] The finished product collection chamber 41 is connected to a microsphere cylinder 7 via a pipeline, so that the qualified microsphere solution in the microsphere cylinder 7 can be transferred to the filling mechanism in subsequent processes for subsequent filling operations.

[0066] Obviously, those skilled in the art can make various modifications and variations to this invention without departing from its spirit and scope. Therefore, if these modifications and variations fall within the scope of the claims of this invention and their equivalents, this invention also intends to include these modifications and variations.

Claims

1. A microsphere preparation system, characterized in that, include: Raw material supply module (1), microsphere preparation module (2), inspection and monitoring module (3), and screening and sorting module (4); The output end of the raw material supply module (1) is connected to the input end of the microsphere preparation module (2). The raw material supply module (1) is used to buffer the raw material liquid required for microsphere preparation and to deliver the buffered raw material liquid under constant pressure after diversion. The microsphere preparation module (2) is used to receive the raw material liquid and prepare a microsphere solution. The raw material supply module (1) includes an oil phase conveying pipeline (11) and an aqueous phase conveying pipeline (12); The oil phase delivery pipeline (11) and the water phase delivery pipeline (12) are respectively connected to the two input ends of the microsphere preparation module (2), and a delivery pump (13) is provided on the oil phase delivery pipeline (11) and the water phase delivery pipeline (12). The inspection and monitoring module (3) is movably disposed on one side of the microsphere preparation module (2) and is used to monitor the microsphere solution prepared by the microsphere preparation module (2); The screening and sorting module (4) includes a finished product collection bin (41), a waste collection bin (42), and a drive traction component (43). Both the finished product collection bin (41) and the waste collection bin (42) are located below the hose (5) connected to the output end of the microsphere preparation module (2); The drive traction component (43) is connected to the hose (5) and is used to control the outlet of the hose (5) to selectively point to the finished product collection bin (41) or the waste collection bin (42). The drive traction component (43) is configured as an electric telescopic rod; The finished product collection bin (41) and the waste collection bin (42) are arranged parallel to each other along the extension and retraction direction of the electric telescopic rod; The microsphere preparation module (2) includes an oil phase pressure control tank (21), an aqueous phase flow rate control tank (22), and a piezoelectric valve microsphere preparation unit (23). One end of the oil phase pressure control tank (21) is connected to the oil phase delivery pipeline (11), and the other end is connected to the piezoelectric valve microsphere preparation unit (23); One end of the aqueous phase flow rate control tank (22) is connected to the aqueous phase delivery pipeline (12), and the other end is connected to the piezoelectric valve microsphere preparation unit (23); The piezoelectric valve microsphere preparation unit (23) is used to receive the raw material liquid and prepare a microsphere solution; The output end of the piezoelectric valve microsphere preparation unit (23) is connected to the hose (5). The raw material supply module (1), the microsphere preparation module (2), the inspection and monitoring module (3), and the drive traction component (43) are all connected to the same control terminal signal. The control terminal is used to coordinate the execution of each process step and realize fully automated control based on sensor signals and preset process parameters.

2. The microsphere preparation system as described in claim 1, characterized in that, The piezoelectric valve microsphere preparation unit (23) has an oil phase flow rate controller (231) and a temperature controller (232), which are used to control the flow rate of the oil phase liquid and the temperature during the preparation of the microsphere solution, respectively.

3. The microsphere preparation system as described in claim 1, characterized in that, An observation chamber (6) is provided between the piezoelectric valve microsphere preparation unit (23) and the hose (5). The observation chamber (6) has a transparent window (61) facing the inspection and monitoring module (3).

4. The microsphere preparation system as described in claim 1, characterized in that, The piezoelectric valve microsphere preparation unit (23) is provided in multiple sets, and is arranged in rows at equal intervals along the moving direction of the inspection and monitoring module (3).

5. The microsphere preparation system according to any one of claims 1-4, characterized in that, The inspection and monitoring module (3) includes a linear guide rail (31) and a visual monitoring module (32); The linear guide rail (31) is disposed on one side of the microsphere preparation module (2), and the visual monitoring module (32) is slidably mounted on the linear guide rail (31) through a drive mechanism; The visual monitoring module (32) is used to acquire the contour parameters, particle size parameters and surface depression parameters of the microspheres. The control terminal determines whether the microspheres are abnormal based on the microsphere parameters provided by the visual monitoring module (32) and the preset standard parameters.

6. The microsphere preparation system according to any one of claims 1-4, characterized in that, Both the finished product collection bin (41) and the waste collection bin (42) have an inclined inner cavity bottom wall.

7. The microsphere preparation system according to any one of claims 1-4, characterized in that, The finished product collection bin (41) is connected to a microsphere cylinder (7) via a pipeline.

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