一种增强草地贪夜蛾抗杆状病毒功能的肠道共生菌及其应用

CN121320160BActive Publication Date: 2026-07-17INST OF ZOOLOGY CHINESE ACAD OF SCI

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
INST OF ZOOLOGY CHINESE ACAD OF SCI
Filing Date
2025-10-24
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

The application of existing baculoviruses in the target pest fall armyworm faces resistance issues and also infects non-target beneficial insects. Enhancing the antiviral ability of target pests and avoiding negative impacts on beneficial insects is the key to biological control.

Method used

A specific gut strain, Glutamicibactersoli, was screened out. It was isolated, purified, and identified to enhance the fall armyworm's resistance to baculovirus infection, regulate the gut microbiota structure to reduce the infection susceptibility of beneficial insects, and a sterile model was established by feeding antibiotics and then reintroduced with the strain. Virus lethality and gene expression were monitored.

Benefits of technology

It significantly reduced the mortality rate of insects caused by viral infection, prolonged the median lethal time, inhibited viral gene expression, and enhanced the resistance of fall armyworm to baculovirus, providing experimental evidence and strategies for biocontrol.

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Abstract

本发明公开了一种增强草地贪夜蛾抗杆状病毒功能的肠道共生菌及其应用,涉及微生物技术领域,包括该菌株来源于草地贪夜蛾中肠,经分离纯化并通过16S rDNA基因测序鉴定,序列长度为1397 bp,与已知Glutamicibacter soli的序列同源性为99.93%。所述菌株保藏于中国科学院微生物研究所,保藏编号为CGMCC No.34972。本发明提供了一种增强草地贪夜蛾抗杆状病毒功能的肠道共生菌及其应用,为进一步揭示宿主—病原体—共生菌三者之间的互作机制提供了实验依据,同时也为实现鳞翅目害虫的靶向生物防控及非靶标益虫保护的综合性病毒防控策略提供了技术基础。
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