一种改善睡眠障碍的益生菌组合物、后生元及其制备方法和应用

By fermenting and processing specific types of probiotics to produce postbiotics, the problem of insufficient sleep disorder regulation in existing technologies has been solved, achieving the effects of improving sleep quality and reducing nighttime awakenings, and restoring normal sleep cycles.

CN121379858BActive Publication Date: 2026-07-17湖南益百益优生物科技有限公司

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
湖南益百益优生物科技有限公司
Filing Date
2025-12-16
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

Existing probiotic compositions and prebiotics have varying effects on improving sleep disorders, making it difficult to effectively regulate sleep cycles and reduce nighttime awakenings. Current technologies have failed to fully utilize gut microbiota to regulate neuroendocrine balance in order to improve sleep.

Method used

The initial complex is fermented using a specific combination of probiotic species (Bifidobacterium longum subsp. BN08, Lactobacillus acidophilus BN10, Bifidobacterium breve BN09, and Lactobacillus reuteri BN01), and then processed into a postbiotic through homogenization, concentration, and spray drying. This process releases bioactive substances, regulates the balance of intestinal flora, and promotes the secretion of cholecystokinin.

Benefits of technology

Improve sleep quality, reduce the number of nighttime awakenings, restore normal sleep cycles, increase sleep latency and duration, and improve sleep disorder symptoms.

✦ Generated by Eureka AI based on patent content.

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Abstract

本发明提供了一种改善睡眠障碍的益生菌组合物、后生元及其制备方法和应用。该益生菌组合物由长双歧杆菌长亚种BN08、嗜酸乳杆菌BN10、短双歧杆菌BN09、罗伊氏粘液乳杆菌BN01组成;该后生元是通过上述益生菌组合物分批次发酵初始复合物,再经过均质、浓缩、喷干等工艺制备而成,所述初始复合物由以下原材料组成:黑豆、花生仁、燕麦、百合、枸杞子、大枣、白砂糖、纯化水。本发明的产品营养丰富、易吸收,人体食用此后生元一段时间后,能够减少夜间觉醒次数,提高睡眠质量,改善睡眠障碍。
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