基于深度学习的快速磁共振CEST定量方法及成像设备

By using deep learning to predict the reference z-spectrum and optimize frequency offset selection, the problems of long imaging time and slow calculation speed in CEST imaging technology are solved, achieving rapid and accurate CEST quantification, which has good clinical application value.

CN121385757BActive Publication Date: 2026-07-17ZHEJIANG UNIV

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
ZHEJIANG UNIV
Filing Date
2025-10-31
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

Existing CEST imaging technology suffers from long imaging time and slow calculation speed during quantitative signal acquisition and post-processing. In particular, the computational intensity and long processing time of the NEMR method limit its clinical application.

Method used

We employ a fast magnetic resonance CEST quantitative method based on deep learning. By predicting the reference z-spectrum through a deep neural network group and combining it with a BM equation decoder, we optimize the frequency shift selection, reduce the number of necessary frequency shifts, and improve computational speed and imaging efficiency.

Benefits of technology

It achieves rapid and accurate CEST quantification, significantly improves calculation speed and imaging time, has good clinical application value, and reduces imaging time and post-processing calculation time.

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Abstract

本发明公开了一种基于深度学习的快速磁共振CEST定量方法及成像设备,属于磁共振技术领域。本发明方法包括:采集待成像对象的磁共振CEST数据;使用一个预先训练好的深度神经网络组,其由编码器和BM方程解码器构成,其输入数据的频率偏移是经过选择的;利用深度神经网络组计算参考z谱;计算得到CEST定量信号;获取CEST定量信号图。本发明通过预先进行频率选择,筛选出了多个关键饱和频率偏移组合,并利用物理信息网络模式进行训练,从而在保证定量图像质量的前提下,提高了CEST定量速度,减少了定量所需的数据数量,减少成像所需时间。
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