Gas target device for isotope production

Abstract

This invention discloses a gas target device for isotope production. The gas target device includes: a base having a channel; a water-cooled jacket mounted on the base, the water-cooled jacket having a water-cooled cavity for circulating a water-cooling medium; and a target body mounted on the base and including a target body located within the water-cooled cavity and having a target cavity. The target cavity, the channel, and the accelerator beam outlet are arranged sequentially along a predetermined direction. According to the gas target device for isotope production according to embodiments of this invention, by providing a water-cooled jacket for cooling the target body, damage to the target body caused by excessively high target gas temperature is avoided. Furthermore, the target gas can receive beam irradiation with a higher flow rate, thereby increasing isotope yield.

Description

Technical Field

[0001] This invention relates to the field of gas target technology, and more specifically, to a gas target apparatus for isotope production. Background Technology

[0002] Of the more than one hundred elements discovered so far, approximately three hundred are stable isotopes, while over fifteen hundred are radioactive isotopes. Isotope technology is widely used in agriculture, industry, medicine, geology, and archaeology. In nuclear medicine, radioactive isotope tracing is frequently used to scan organs such as the thyroid, liver, kidneys, brain, heart, and pancreas for the diagnosis and treatment of diseases such as tumors, offering advantages of simplicity and safety. 99m Tc, 18 F, 131 Radiopharmaceuticals, represented by radionuclides such as I, have been widely used in clinical diagnosis and treatment. PET and SPECT imaging are both applications of radioisotopes.

[0003] Radioactive isotopes are mainly prepared through reactor irradiation, accelerator preparation, natural isotope separation, high-level radioactive waste extraction, and generator preparation. Cyclotrons, due to their technical characteristics such as accelerating a wide variety of particles, a broad energy range, and high average beam intensity, are one of the main devices for preparing medical radioactive isotopes and are currently commonly used... 18 Preparation of F-FDG drugs.

[0004] Accelerators produce radioactive isotopes by accelerating a particle beam to bombard target material, causing nuclear reactions. The device that holds the target material and receives the beam irradiation is called the target system. Depending on the physical state of the target material, target systems can be classified as solid targets, liquid targets, and gaseous targets.

[0005] Among them, the gas target is an indispensable component of the accelerator for producing medical isotopes. It can be used to produce gaseous isotopes, such as those used in the production of... 11 C 15 O and 123 I isotopes. However, gas targets in related technologies suffer from insufficient heat dissipation, making it difficult to increase beam intensity and creating bottlenecks in production capacity. Summary of the Invention

[0006] The present invention aims to at least solve one of the technical problems existing in the prior art. Therefore, one object of the present invention is to provide a gas target device for isotope production, wherein the gas target device improves heat dissipation capacity, which is beneficial to increasing isotope yield.

[0007] A gas target device for isotope production according to an embodiment of the present invention includes: a base having a channel; a water-cooled jacket mounted on the base and having a water-cooled cavity for circulating a water-cooling medium; and a target body mounted on the base and including a target body located within the water-cooled cavity and having a target cavity, wherein the target cavity, the channel, and the accelerator beam outlet are arranged sequentially along a predetermined direction.

[0008] According to an embodiment of the present invention, a gas target device for isotope production is provided with a water-cooled jacket to cool the target, thereby preventing the target gas from being damaged due to excessively high temperature. As a result, the target gas can be irradiated by a beam with a higher flow rate, thus increasing the isotope yield.

[0009] In addition, the gas target device for isotope production according to the above embodiments of the present invention may also have the following additional technical features:

[0010] According to some embodiments of the present invention, the outer surface of the target body is provided with grooves and / or protrusions.

[0011] According to some embodiments of the present invention, a target sealing membrane is provided between the channel and the target cavity, and the target sealing membrane seals the opening of the target cavity; a vacuum membrane is provided in the channel, and the vacuum membrane is located on the side of the target sealing membrane away from the target cavity; the channel includes a cooling cavity located between the target sealing membrane and the vacuum membrane, and the cooling cavity is filled with a gaseous cooling medium.

[0012] According to some embodiments of the present invention, the thickness of the target sealing film is 10 μm to 60 μm; and / or, the thickness of the vacuum film is 10 μm to 60 μm.

[0013] According to some embodiments of the present invention, the target is made of aluminum alloy, titanium, nickel alloy, tantalum or silver; and / or, the target sealing film is made of aluminum, titanium, Haver or niobium; and / or, the vacuum film is made of aluminum, titanium, Haver or niobium.

[0014] According to some embodiments of the present invention, the inner diameter of at least a portion of the target cavity gradually increases in the direction away from the channel in the set direction, or the inner diameter of the target cavity is equal everywhere.

[0015] According to some embodiments of the present invention, the water-cooled jacket is provided with a first flange at one end near the base, and the target body is provided with a second flange on the outer peripheral surface at one end near the base. The first flange, the second flange and the base are connected by fasteners. The water-cooled jacket is provided with a water-cooling inlet at one end away from the base, and the first flange is provided with a water-cooling outlet. The second flange is provided with a target gas inlet and a target gas outlet.

[0016] According to some embodiments of the present invention, the gas target device further includes: a cooling circuit communicating with the target cavity to allow target gas to circulate within the cooling circuit and the target cavity; and a shielding shell filled with coolant, wherein the cooling circuit is located within the shielding shell and immersed in the coolant.

[0017] According to some embodiments of the present invention, the shielding shell is provided with a connection port for connecting to a compression cooling device to cool the coolant through the compression cooling device.

[0018] Additional aspects and advantages of the invention will be set forth in part in the description which follows, and in part will be obvious from the description, or may be learned by practice of the invention. Attached Figure Description

[0019] The above and / or additional aspects and advantages of the present invention will become apparent and readily understood from the description of the embodiments taken in conjunction with the following drawings, in which:

[0020] Figure 1 This is a schematic diagram of the structure of a gas target device according to an embodiment of the present invention;

[0021] Figure 2 This is a front view of a gas target device according to an embodiment of the present invention;

[0022] Figure 3 yes Figure 2 A cross-sectional view along the direction indicated by line AA;

[0023] Figure 4 This is a right view of a gas target device according to an embodiment of the present invention;

[0024] Figure 5 yes Figure 4 A cross-sectional view along the direction indicated by line BB;

[0025] Figure 6 This is a partial structural schematic diagram of a gas target device according to an embodiment of the present invention;

[0026] Figure 7 This is a schematic diagram of the cooling circuit and shielding housing according to an embodiment of the present invention.

[0027] Figure label:

[0028] Gas target device 100;

[0029] 10 base; 101 channel; 102 cooling chamber; 103 cooling inlet; 104 cooling outlet; 11 first part; 12 second part;

[0030] Water-cooled jacket 20; water-cooled cavity 201; water-cooled inlet 202; water-cooled outlet 203; first flange 21;

[0031] Target body 30; Target cavity 311; Groove 312; Second flange 32; Target gas inlet 321; Target gas outlet 322;

[0032] Target sealing membrane 41; vacuum membrane 42; fastener 40;

[0033] Cooling circuit 50; shielding housing 51;

[0034] Collimator 60. Detailed Implementation

[0035] Embodiments of the present invention are described in detail below. Examples of these embodiments are shown in the accompanying drawings, wherein the same or similar reference numerals denote the same or similar elements or elements having the same or similar functions throughout. The embodiments described below with reference to the accompanying drawings are exemplary and are only used to explain the present invention, and should not be construed as limiting the present invention.

[0036] In the description of this invention, it should be understood that the terms "center," "longitudinal," "lateral," "length," "width," "thickness," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," "clockwise," "counterclockwise," "axial," "radial," and "circumferential" indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are used only for the convenience of describing this invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this invention.

[0037] In the description of this invention, "first feature" and "second feature" may include one or more of the features, "multiple" means two or more, "above" or "below" the second feature may include the first and second features being in direct contact, or the first and second features being in contact through another feature between them, and "above," "over," and "on top" the second feature may include the first feature being directly above or diagonally above the second feature, or simply indicate that the first feature is at a higher horizontal level than the second feature.

[0038] A gas target apparatus 100 for isotope production according to an embodiment of the present invention is described below with reference to the accompanying drawings.

[0039] Reference Figures 1-6 As shown, the gas target device 100 for isotope production according to an embodiment of the present invention may include: a base 10, a water-cooled jacket 20, and a target 30.

[0040] Specifically, the base 10 has a channel 101. A water-cooled jacket 20 is mounted on the base 10 and has a water-cooled cavity 201 for the flow of water-cooling medium. A target 30 is mounted on the base 10 and includes a target body 31, which is located within the water-cooled cavity 201 and has a target cavity 311. The target cavity 311, the channel 101, and the accelerator beam outlet are arranged sequentially along a set direction.

[0041] Here, the cooling medium can be, but is not limited to, deionized water or other fluids. The target gas can be, but is not limited to, used in the production of medical isotopes, such as... 11 C 15 O and 123 I etc.

[0042] After being extracted by the accelerator, the beam can be directed through the beam outlet in a predetermined direction, passing through channel 101 and irradiating the target gas within the target cavity 311. Upon irradiation, energy is deposited in the target gas, causing its temperature to rise. By placing the target body 31 within the water-cooling cavity 201, the target body 31 is immersed in a water-cooling medium, which cools the target body 31, preventing damage to the target body 30 due to excessively high target gas temperature. Furthermore, the water-cooling medium within the water-cooling cavity 201 can contact and exchange heat with the entire outer surface of the target body 31, resulting in better heat dissipation. Therefore, the target gas can receive beam irradiation with a higher flow rate, increasing isotope yield.

[0043] According to an embodiment of the present invention, the gas target device 100 for isotope production is provided with a water-cooled jacket 20 for cooling the target 30, so as to avoid damage to the target 30 due to excessively high target gas temperature, and thus the target gas can be irradiated by a beam with a higher flow rate, thereby increasing the isotope yield.

[0044] According to some embodiments of the present invention, such as Figure 6 As shown, the outer surface of the target body 31 may be provided with at least one of grooves 312 and protrusions. Thus, the outer surface of the target body 31 can be formed as a concave-convex surface, increasing the surface area, thereby increasing the heat exchange area between the target body 31 and the water cooling medium in the water cooling cavity 201, resulting in higher heat exchange efficiency and better effect in preventing the target gas temperature from becoming too high.

[0045] Here, the specific structure of the groove 312 and the protrusion is not particularly limited. For example, the groove 312 and the protrusion can extend in a ring shape along the circumference of the target body 31; or the groove 312 and the protrusion can extend spirally along the circumference of the target body 31; or as... Figure 6 As shown, the groove 312 and the protrusion can extend in a long strip along a set direction, and multiple protrusions are arranged along the circumference of the target body 31, making the processing of the concave and convex structure more convenient.

[0046] In some embodiments of the present invention, such as Figure 3 and Figure 5As shown, a target sealing membrane 41 is provided between the channel 101 and the target cavity 311. The target sealing membrane 41 seals the opening of the target cavity 311 to prevent the target gas in the target cavity 311 from leaking into the channel 101. A vacuum membrane 42 is provided inside the channel 101. The vacuum membrane 42 is located on the side of the target sealing membrane 41 away from the target cavity 311 to achieve an internal vacuum in the accelerator and prevent the target gas from diffusing into the accelerator cavity.

[0047] As the beam passes through the vacuum membrane 42 and the target sealing membrane 41, some energy is deposited on the membranes. If no cooling measures are taken, the membrane temperature will continuously rise during irradiation, even reaching the material's melting point, causing the membrane to rupture and the vacuum inside the accelerator to fail. In the worst-case scenario, both the vacuum membrane 42 and the target sealing membrane 41 will rupture, and the radioactive target gas will diffuse into the accelerator cavity and even into the air after irradiation.

[0048] Therefore, in some embodiments, channel 101 includes a cooling cavity 102 located between target sealing membrane 41 and vacuum membrane 42, the cooling cavity 102 being filled with a gaseous cooling medium.

[0049] The gas cooling medium can simultaneously cool the vacuum membrane 42 and the target sealing membrane 41, preventing the membrane temperature from becoming too high due to energy deposition and greatly reducing the risk of membrane rupture. The gas cooling medium can be, but is not limited to, helium.

[0050] In some embodiments, such as Figure 3 As shown, the base 10 is provided with a cooling inlet 103 and a cooling outlet 104, which are respectively connected to the cooling chamber 102. The gaseous cooling medium can flow into the cooling chamber 102 through the cooling inlet 103 to cool the vacuum membrane 42 and the target sealing membrane 41, and can also flow out of the cooling chamber 102 through the cooling outlet 104 to facilitate cooling outside the gas target device 100, thereby achieving gaseous cooling medium circulation and improving heat dissipation and stability.

[0051] In some embodiments, such as Figure 3 As shown, a collimator 60 is provided in the channel 101, and the collimator 60 is located on the side of the vacuum membrane 42 away from the target cavity 311. The beam drawn out from the beam outlet can first pass through the collimator 60, and the size of the beam spot is limited by the collimator 60 to improve the isotope production effect.

[0052] In some specific embodiments, such as Figures 1-5As shown, the base 10 includes a first part 11 and a second part 12. The second part 12 is located on the side of the first part 11 facing away from the target 30. The target 30 and the water-cooled jacket 20 can be connected to the first part 11. The first part 11 has a cooling chamber 102, a cooling inlet 103, and a cooling outlet 104. A target sealing membrane 41 is sandwiched between the first part 11 and the target 30, a vacuum membrane 42 is sandwiched between the first part 11 and the second part 12, and a collimator 60 is disposed within the second part 12. The base 10 with the above structure makes the assembly of components such as the target sealing membrane 41, the vacuum membrane 42, and the collimator 60 more convenient and facilitates sealing.

[0053] The target sealing membrane 41 and the vacuum membrane 42 need to have high strength, high temperature resistance, non-deformation, and minimal deposition beam energy. Therefore, in some embodiments, the thickness of the target sealing membrane 41 is 10 μm to 60 μm, enabling the target sealing membrane 41 to withstand the pressure and temperature rise within the target cavity 311, thus meeting the strength and high temperature resistance requirements of the target sealing membrane 41. In some embodiments, the thickness of the vacuum membrane 42 is 10 μm to 60 μm, enabling the vacuum membrane 42 to withstand the pressure and temperature rise within the cooling cavity 102, thus meeting the strength and high temperature resistance requirements of the vacuum membrane 42.

[0054] In some embodiments, the target sealing membrane 41 is made of aluminum, titanium, Haver, or niobium; the vacuum membrane 42 is made of aluminum, titanium, Haver, or niobium. The target sealing membrane 41 and the vacuum membrane 42 have better strength and high-temperature resistance.

[0055] For example, in some specific embodiments, the vacuum membrane 42 is located between the accelerator vacuum and the cooling chamber 102. The cooling medium in the cooling chamber 102 is helium, and the operating pressure is approximately 140 kPa. Therefore, the vacuum membrane 42 is a 20 μm thick titanium membrane. The target sealing membrane 41 is located between the cooling chamber 102 and the target chamber 311. The initial pressure of the target chamber 311 is 1.2 MPa, and as the beam irradiates the pressure and temperature inside the target chamber 311, it increases but does not exceed 5 MPa. Therefore, the target sealing membrane 41 is a 30 μm thick Haver membrane. Both the vacuum membrane 42 and the target sealing membrane 41 are sealed using O-rings and elastic metal sealing rings.

[0056] In some embodiments, the target 30 is made of aluminum alloy, titanium, nickel alloy, tantalum, or silver. The target 30 has high stress strength and high pressure resistance, and also has good chemical inertness and thermal conductivity.

[0057] Aluminum possesses good strength and corrosion resistance, requiring no cleaning during use. Titanium exhibits good tensile strength and corrosion resistance, and can be cleaned alone with nitric acid or in combination with hydrochloric acid. Nickel alloys, such as stainless steel, can be used as target materials for corrosive gases. Tantalum exhibits excellent corrosion resistance and nuclear stability. Silver possesses the highest thermal and electrical conductivity among metals and does not react with air, water, or many acids under normal conditions.

[0058] According to some embodiments of the present invention, at least a portion of the inner diameter of the target cavity 311 gradually increases in a predetermined direction away from the channel 101, forming this portion of the target cavity 311 into a conical cavity, which can adapt to beam scattering and is beneficial for obtaining higher yield and higher activity. For example, in... Figure 3 and Figure 5 In the example shown, the target cavity 311 includes a spherical cavity and a conical cavity, with the small end of the conical cavity close to the channel 101 and the large end of the conical cavity connected to the spherical cavity.

[0059] According to other embodiments of the present invention, the inner diameter of the target cavity 311 is equal everywhere, so that the target cavity 311 is formed into a straight cylinder (or cylindrical shape), which has a simple structure and is easy to process.

[0060] In some embodiments of the present invention, such as Figure 1 and Figure 5 As shown, the water-cooled jacket 20 has a first flange 21 at one end near the base 10, and the target body 31 has a second flange 32 on its outer circumferential surface at one end near the base 10. The first flange 21, the second flange 32, and the base 10 are connected by fasteners 40. The fasteners 40 allow for the connection and fixation of the water-cooled jacket 20, the target body 31, and the base 10, simplifying the installation structure and reducing the number of openings on the first flange 21 and the second flange 32, thus lowering the risk of seal failure.

[0061] In addition, such as Figure 3 As shown, the water-cooled jacket 20 is provided with a water-cooled inlet 202 at the end away from the base 10, and the first flange 21 is provided with a water-cooled outlet 203, so that the water-cooling medium can flow into the water-cooled cavity 201 from the end of the water-cooled jacket 20 away from the base 10, and then flow towards the end of the water-cooled jacket 20 near the base 10. During this process, the water-cooling medium flows through the surface of the target body 31 and is opposite to the irradiation direction of the beam inside the target body 31, which is beneficial to improving the cooling effect on the target gas.

[0062] In addition, in embodiments where grooves 312 and protrusions extending in a set direction are provided on the outer surface of the target body 31, the extending direction of the grooves 312 and protrusions is closer to the flow direction of the water cooling medium, which is beneficial to reducing flow resistance.

[0063] In addition, in embodiments where the target body 31 includes a spherical cavity, the end face of the target body 31 facing the water-cooling inlet 202 can be formed as a spherical surface, which is beneficial to reduce the water inlet resistance at the water-cooling inlet 202.

[0064] In addition, continue to refer to Figure 3As shown, the second flange 32 is provided with a target gas inlet 321 and a target gas outlet 322, which makes it easier to connect the target cavity 311 to the outside. The second flange 32 also has the functions of installation and fixation and target gas transmission, which helps to simplify the structure.

[0065] According to some embodiments of the present invention, such as Figure 7 As shown, the gas target device 100 further includes a cooling circuit 50 and a shielding housing 51. The cooling circuit 50 is connected to the target cavity 311 to allow the target gas to circulate within the cooling circuit 50 and the target cavity 311. The shielding housing 51 is filled with coolant, and the cooling circuit 50 is located within the shielding housing 51 and immersed in the coolant.

[0066] A gas circuit is formed between the cooling circuit 50 and the target cavity 311. During beam irradiation, the target gas in the target cavity 311 experiences a temperature increase after being irradiated by the beam. Spontaneous gas convection occurs within the gas circuit between the target cavity 311 and the cooling circuit 50, allowing the target gas to circulate and dissipate heat within the cooling circuit 50. This allows the target gas to receive beam irradiation of higher intensity, increasing isotope yield. The shielding shell 51 serves as a container for the coolant, which is beneficial for radiation shielding. The coolant can be, but is not limited to, water, oil, and other media.

[0067] In some embodiments, at least a portion of the cooling circuit 50 may be formed as a spiral structure to increase the contact area with the coolant and improve heat dissipation efficiency.

[0068] In some embodiments, the shielding housing 51 is provided with a connection port for connecting to a compression cooling device (such as a compressor) to cool the coolant. The compression cooling device continuously absorbs and dissipates heat from the coolant, enabling the coolant to continuously cool the target gas in the cooling circuit 50, which is beneficial for further increasing the isotope yield.

[0069] The following detailed description of a gas target apparatus 100 for isotope production according to a specific embodiment of the present invention is given with reference to the accompanying drawings. It is to be understood that the following description is merely illustrative and should not be construed as limiting the invention.

[0070] like Figures 1-7 As shown, a gas target device 100 according to a specific embodiment of the present invention includes a base 10, a water-cooled jacket 20, a target 30, a collimator 60, a vacuum membrane 42, a target sealing membrane 41, a cooling circuit 50, and a shielding shell 51.

[0071] After the beam exits from the accelerator beam outlet, the beam spot size is limited by the collimator 60. The vacuum membrane 42 and the target sealing membrane 41 are used to isolate the internal vacuum of the accelerator and seal the target gas, respectively. Helium gas in the cooling chamber 102 of the base 10 is used to cool the vacuum membrane 42 and the target sealing membrane 41. After the target gas is irradiated, energy will also be deposited, and the temperature will rise. Deionized water in the water-cooled jacket 20 is used to cool the target 30 to prevent the target gas temperature from becoming too high and causing damage to the target 30.

[0072] The initial pressure of the target gas is between 0.8 and 1.2 MPa. As the beam irradiates, both the temperature and pressure of the target gas will rise. Under good heat dissipation conditions, the pressure in thermal steady state generally will not exceed 5 MPa. Aluminum alloy 6061 is used as the material for the target body 30, the vacuum film 42 is a 20 μm thick titanium film, and the target sealing film 41 is a 30 μm thick Haver film.

[0073] Cooling circuit 50 is connected to target cavity 311, forming a gas circuit with target cavity 311. Shielding shell 51 serves as a coolant container to shield against radiation. The coolant is connected to a compressor for continuous heat absorption and dissipation. During beam irradiation, the target gas in target cavity 311 experiences a temperature increase after beam irradiation, spontaneously forming gas convection within the gas circuit of target cavity 311 and cooling circuit 50, allowing the target gas to circulate and dissipate heat within cooling circuit 50.

[0074] Other configurations and operations of the gas target device 100 according to embodiments of the present invention are known to those skilled in the art and will not be described in detail here.

[0075] In the description of this invention, it should be noted that, unless otherwise explicitly specified and limited, the terms "installation," "connection," and "linking" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection of two components. Those skilled in the art can understand the specific meaning of the above terms in this invention based on the specific circumstances.

[0076] In the description of this specification, the references to terms such as "embodiment," "specific embodiment," and "example" indicate that a specific feature, structure, material, or characteristic described in connection with that embodiment or example is included in at least one embodiment or example of the present invention. In this specification, the illustrative expressions of the above terms do not necessarily refer to the same embodiment or example. Furthermore, the specific features, structures, materials, or characteristics described may be combined in any suitable manner in one or more embodiments or examples.

[0077] Although embodiments of the invention have been shown and described, those skilled in the art will understand that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the invention, the scope of which is defined by the claims and their equivalents.

Claims

1. A gas target device (100) for isotope production, characterized in that, include: A seat (10) having a channel (101); A water-cooled jacket (20) is mounted on the base (10) and has a water-cooled cavity (201) for the flow of water-cooling medium. The target body (30) is mounted on the base (10) and includes a target body (31). The target body (31) is located in the water-cooled cavity (201) and has a target cavity (311). The target cavity (311), the channel (101) and the accelerator beam outlet are arranged sequentially along a set direction. The water-cooled jacket (20) has a first flange (21) at one end near the base (10), and the target body (31) has a second flange (32) on its outer circumferential surface at one end near the base (10). The first flange (21), the second flange (32), and the base (10) are connected by fasteners (40). The water-cooled jacket (20) has a water-cooling inlet (202) at one end away from the base (10), and the first flange (21) has a water-cooling outlet (203). The second flange (32) has a target gas inlet (321) and a target gas outlet (322). The gas target device (100) further includes a cooling circuit (50) and a shielding shell (51). The cooling circuit (50) is connected to the target cavity (311) so that the target gas circulates within the cooling circuit (50) and the target cavity (311). The shielding shell (51) is filled with coolant, and the cooling circuit (50) is located within the shielding shell (51) and immersed in the coolant.

2. The gas target device (100) for isotope production according to claim 1, characterized in that, The outer surface of the target body (31) is provided with grooves (312) and / or protrusions.

3. The gas target device (100) for isotope production according to claim 1, characterized in that, A target sealing membrane (41) is provided between the channel (101) and the target cavity (311), and the target sealing membrane (41) seals the opening of the target cavity (311); a vacuum membrane (42) is provided inside the channel (101), and the vacuum membrane (42) is located on the side of the target sealing membrane (41) away from the target cavity (311); the channel (101) includes a cooling cavity (102) located between the target sealing membrane (41) and the vacuum membrane (42), and the cooling cavity (102) is filled with a gaseous cooling medium.

4. The gas target apparatus (100) for isotope production according to claim 3, characterized in that, The thickness of the target sealing film (41) is 10 μm to 60 μm; and / or, The thickness of the vacuum membrane (42) is 10μm~60μm.

5. The gas target device (100) for isotope production according to claim 3, characterized in that, The target (30) is made of aluminum alloy, titanium, nickel alloy, tantalum, or silver; and / or, The target sealing film (41) is made of aluminum, titanium, Haver, or niobium; and / or, The vacuum membrane (42) is made of aluminum, titanium, Haver or niobium.

6. The gas target apparatus (100) for isotope production according to claim 1, characterized in that, The inner diameter of at least a portion of the target cavity (311) gradually increases in the set direction away from the channel (101), or the inner diameter of the target cavity (311) is equal everywhere.

7. The gas target apparatus (100) for isotope production according to any one of claims 1-6, characterized in that, The shielding shell (51) is provided with a connection port for connecting to a compression cooling device to cool the coolant.

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