一种体内塑化剂去除用的复合益生菌制剂制备方法
By using a compound probiotic preparation that cross-links L-aspartic acid with carboxylated β-cyclodextrin and coordinates with iron ions from green tea extract, the problems of low survival rate and unstable release of probiotics in the gastrointestinal environment are solved, achieving the effect of highly efficient removal of hydrophobic plasticizers.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- KEMENG BIOTECHNOLOGY (HANGZHOU) CO LTD
- Filing Date
- 2025-11-05
- Publication Date
- 2026-07-17
AI Technical Summary
Current probiotic preparations have low survival rates and unstable release in the gastrointestinal environment, making it difficult to effectively bind and remove hydrophobic plasticizers. Furthermore, they exhibit poor batch-to-batch consistency, affecting their stability and efficacy in vivo.
The preparation method of compound probiotic formulation is adopted, which forms a stable embedded structure by cross-linking L-aspartic acid with carboxylated β-cyclodextrin, and combines calcium ion cross-linking and green tea extract-iron ion coordination to form a multi-layer coating, thereby improving the stability and selective binding ability of probiotics in the gastrointestinal tract.
It improves the survival rate and activity stability of probiotics in the gastrointestinal tract, enables the controlled release of probiotics and efficient removal of hydrophobic plasticizers, and ensures the stability and release control capability of the formulation.
Smart Images
Figure SMS_9