一种基于深度学习的阿尔兹海默症患者脑熵监测方法及系统

By using deep learning-based methods to perform signal denoising, feature extraction, and pattern recognition on brain signals from Alzheimer's patients, this approach solves the problem of accurately monitoring disease progression in existing technologies. It achieves fully automated analysis from raw signals to precise early warnings, improving the accuracy and personalization of disease progression monitoring.

CN121460128BActive Publication Date: 2026-07-17ANHUI UNIV OF SCI & TECH

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
ANHUI UNIV OF SCI & TECH
Filing Date
2025-11-03
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

Existing Alzheimer's disease monitoring methods are unable to fully capture the dynamic changes in brain activity. In particular, when faced with individual differences and the diversity of disease development, they cannot accurately distinguish the characteristics of different stages of the disease, resulting in inaccurate judgment of disease progression and missing the critical opportunity for early intervention.

Method used

Employing a deep learning-based approach, this method achieves fully automated analysis from raw signals to precise warnings through signal denoising, feature extraction, pattern recognition, and classification-based early warning. This includes collecting brain signal data, denoising, extracting brain entropy index sequences, pattern recognition, classification, and key node evaluation, ultimately outputting personalized progression warning signals.

Benefits of technology

It improves the accuracy and personalization of disease progression monitoring, providing patients with timely early warnings and personalized intervention plans.

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Abstract

本发明属于脑电信号处理技术领域,涉及一种基于深度学习的阿尔兹海默症患者脑熵监测方法及系统,方法包括:采集目标阿尔兹海默症患者的大脑信号数据并进行降噪,基于去噪后的大脑信号序列提取多层次脑熵值,确定脑熵指标序列;根据脑熵指标序列获取时间窗内的局部波动特征,输入卷积神经网络模型判断潜在的异常模式;从异常模式中提取与疾病进展相关的动态变化向量,输入支持向量机分类器获取分类后的疾病阶段标签;根据疾病阶段标签获取相邻阶段间的差异度并进行评估,确定关键节点;获取关键节点对应脑熵特征的上下文数据,通过序列比对算法对上下文数据进行匹配,输出个性化的进展预警信号。本发明能够提升疾病进展监测的准确性与个性化水平。
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