一种琥珀酸-烟酰胺共晶及其制备方法和应用
By preparing succinic acid-niacinamide cocrystals, the problems of niacinamide stability and short retention time of succinic acid were solved, achieving long-lasting whitening and oil-controlling effects on the skin surface, which is suitable for personal care products, cosmetics and skin care products.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- PROYA COSMETICS CO LTD
- Filing Date
- 2026-01-09
- Publication Date
- 2026-07-17
AI Technical Summary
In existing technologies, niacinamide has poor stability, succinic acid has a short retention time on the skin surface and is difficult to exert a long-lasting soothing or oil-controlling effect, and there are no reports on technical solutions for succinic acid and niacinamide to form specific crystal form supramolecular cocrystals.
Succinic acid-nicotinamide cocrystal was prepared using supramolecular cocrystal technology. A specific molar ratio and solvent system were used, combined with gradient cooling crystallization and vacuum drying, to form a stable triclinic cocrystal structure, which enhances the stability of nicotinamide and the skin residue effect of succinic acid.
The prepared succinic acid-niacinamide cocrystal improves the stability of niacinamide and its residual effect on the skin surface, significantly improving its whitening and oil-controlling effects, and is suitable for personal care products, cosmetics and skin care products.
Smart Images
Figure CN121471135B_ABST