一种多模态磁共振支架再狭窄预测方法与系统

By standardizing and registering multimodal magnetic resonance imaging (MRI) data with initial clinical data, an alignment index structure is generated, static and dynamic features are extracted, individual feature vectors are constructed, and predictions are made using a pre-trained model. This solves the lag problem in ISR management and enables individualized risk prediction and report generation for intracranial arterial stent restenosis.

CN121528573BActive Publication Date: 2026-07-17THE NAVAL MEDICAL UNIV OF PLA

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
THE NAVAL MEDICAL UNIV OF PLA
Filing Date
2025-11-19
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

Existing technologies have significant limitations in the management of restenosis (ISR) after stent implantation for intracranial atherosclerotic stenosis. They cannot effectively monitor the early pathological process of ISNA, lack personalized prediction tools, and existing multimodal magnetic resonance stent restenosis prediction schemes suffer from problems such as unstable registration across time points and inconsistent feature sets, making it difficult to achieve continuous risk prediction and report generation.

Method used

By acquiring multimodal magnetic resonance imaging and structured clinical preliminary data, standardization and artifact suppression, registration and alignment are performed to generate an alignment index structure. Candidate region localization and segmentation are performed to generate static and dynamic feature sets, which are then encoded to construct individual feature vectors. Pre-trained models are used for prediction, risk probability and evidence tracing packages are generated, and visualization reports are generated, achieving consistent alignment and continuous processing across time points.

Benefits of technology

It enables end-to-end individualized prediction of restenosis risk after intracranial artery stenting, ensuring consistent alignment of static and dynamic characteristics across multiple time points, generating personalized risk prediction reports, and supporting clinical decision-making.

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Abstract

本发明涉及医学健康信息学与临床决策支持领域,尤其涉及一种多模态磁共振支架再狭窄预测方法与系统。该方法包括:获取多模态磁共振影像与结构化临床数据,进行预处理生成对齐索引结构;对影像进行分割与特征提取,得到静态与动态特征集合;对特征与临床指标进行归一化与组合编码生成个体特征向量,利用预训练模型进行推理,并构建可回溯至原始数据的证据溯源映射,生成风险概率与证据溯源包;最后进行多层可视化渲染、结构化报告排版及参数自适应调整,生成包含图像对比、趋势曲线等的可视化报告。本发明整合多模态数据与临床信息,通过可解释的预测模型与自动化报告生成,提升了支架再狭窄预测的准确性与临床决策支持效率。
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