Auxiliary diagnosis method for infant congenital heart disease and heart failure

CN121617599APending Publication Date: 2026-03-06福建省儿童医院
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Patent Information

Application Number
CN202511796797.5
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-12-02
Publication Date
2026-03-06

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Abstract

The invention relates to the technical field of data processing, in particular to an infant congenital heart disease heart failure auxiliary diagnosis method which comprises the following steps: collecting excrement samples of all participants, and then carrying out excrement metabonomics detection to collect metabolite data; selecting intestinal metabolites which are obviously increased compared with the control group in the heart failure group; according to the heart failure severity index NT-BNP, correlation analysis is carried out on child patients in a heart failure group and obviously increased intestinal metabolites, and the average relative abundance of three obviously and positively correlated metabolites of indol, arachidonic acid and erucic acid is selected as a critical value to form an auxiliary diagnosis model; on the basis of accurate metabonomics detection, an objective and repeatable quantitative index is provided by quantifying the relative abundance of three specific metabolites; the diagnosis process is standardized, reliable data support is provided for clinical decision making, and diagnosis and missed diagnosis are reduced.
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