Soothing composition containing prunus laurocerasus oil, method for its preparation and use

Abstract

The application belongs to the technical field of daily cosmetics, and discloses a soothing composition containing Prunus armeniaca oil, a method for preparing the soothing composition, and an application of the soothing composition. The soothing composition contains Prunus armeniaca oil, Terminalia chebula Retz fruit extract, Prunus armeniaca oil ceramide NP, and Plantago major L. seed extract. The soothing composition has excellent soothing, anti-inflammatory, and antioxidant effects, can effectively delay product discoloration, has outstanding stability, is suitable for preparing soothing serum and other skin care products, and has a wide application prospect.

Description

Technical Field

[0001] This invention belongs to the technical field of daily cosmetics, specifically relating to a soothing composition containing sea buckthorn fruit oil and delaying discoloration, as well as its preparation method and application. Background Technology

[0002] Sensitive skin problems often stem from a compromised skin barrier function. When the skin is exposed to external stimuli (such as UV rays, pollutants, and chemicals), it easily develops symptoms like erythema, papules, and especially telangiectasia. Simultaneously, it may experience itching, stinging, tightness, or burning sensations, and the skin may be intolerant to ordinary cosmetics. For people with sensitive skin, daily skincare is crucial. Therefore, soothing skincare products need to simultaneously achieve three core goals: barrier repair, anti-inflammatory soothing, and long-lasting stability. However, current technologies still have significant shortcomings.

[0003] Firstly, soothing skincare products are generally divided into three categories: 1. Barrier repair products, such as ceramides, cholesterol, and fatty acids, strengthen the skin barrier function by replenishing the lipids of the stratum corneum. However, when used alone, their anti-inflammatory ability is weak and they cannot quickly relieve existing inflammatory reactions. 2. Anti-inflammatory products, such as chamomile extract, green tea extract, and dipotassium glycyrrhizate, rely on polyphenols, flavonoids, and other ingredients to inhibit the release of inflammatory factors. However, most products only use single plant extracts or simply combine them with barrier repair ingredients without forming an effective synergistic mechanism, resulting in short-lived and incomplete soothing effects. 3. Moisturizing products, such as olive oil, macadamia seed oil, and caprylic / capric triglycerides, provide moisturizing and hydrating effects, but lack specific anti-inflammatory and barrier repair activities and have poor compatibility with other active ingredients, making it difficult to improve the overall soothing efficiency through combination.

[0004] Secondly, plant extracts (such as polyphenols and flavonoids) are chemically active and are easily oxidized and degraded by light, high temperature and oxygen during storage, which causes the product to darken in color. This not only damages the appearance but also causes the active ingredients to become ineffective, reducing the soothing effect.

[0005] In summary, soothing products still face technical bottlenecks such as poor ingredient synergy and easy oxidation and discoloration. There is an urgent need to develop a new composition that can achieve highly effective soothing and anti-inflammatory effects as well as long-term stable anti-discoloration, in order to meet the needs of people with sensitive skin for gentle, long-lasting, and stable skin care products. Summary of the Invention

[0006] In view of the shortcomings of the prior art, the purpose of this invention is to provide a novel composition that can achieve highly efficient soothing and anti-inflammatory effects as well as long-term stable anti-discoloration, and its preparation method and application.

[0007] To achieve the above objectives, the present invention discloses the following technical solutions: In a first aspect, the present invention provides a soothing composition containing sea buckthorn fruit oil and delaying discoloration, wherein the soothing composition contains the following components in parts by weight: 10-30 parts of sea buckthorn fruit oil; Terminalia chebula fruit extract 1-3 parts; Ceramide NP in sea buckthorn fruit oil: 0.006–0.2 parts; Plantago seed extract 0.01–0.05 parts.

[0008] Preferably, the soothing composition contains the following components in parts by weight: 20-25 parts of sea buckthorn fruit oil; Terminalia chebula fruit extract, 2.2–2.3 parts; Ceramide NP in sea buckthorn fruit oil: 0.02–0.15 parts; Plantago seed extract 0.02–0.04 parts.

[0009] More preferably, the preparation method of the Terminalia chebula fruit extract includes the following steps: Step 1: Place the dried Terminalia chebula fruit in a high-speed grinder and grind it. Then pass it through a 60-mesh sieve to obtain Terminalia chebula fruit powder. Step 2: Place the Terminalia chebula fruit powder in a supercritical CO2 extraction vessel for extraction. Set the extraction pressure to 22 MPa, the extraction temperature to 40-50℃, the CO2 extraction flow rate to 22-25 L / min, and the extraction time to 2-3 h. The volume ratio of supercritical CO2 fluid to mixed entrainer is (5-6):1. The mixed entrainer is composed of anhydrous ethanol and Prickly pear fruit oil. After extraction, remove the fluid and anhydrous ethanol under reduced pressure to obtain Terminalia chebula fruit extract.

[0010] More preferably, the mixed entrainer in step 2 is a mixture of anhydrous ethanol and sea buckthorn oil in a volume ratio of (1.8-2.1):1.

[0011] More preferably, the preparation method of the Terminalia chebula fruit extract includes the following steps: Step 1: Place dried psyllium seeds in a high-speed grinder and grind them. Pass the powder through a 60-mesh sieve to obtain psyllium seed powder. Step 2: Place the psyllium seed powder in a supercritical CO2 extraction vessel for extraction. Set the extraction pressure to 28 MPa, the extraction temperature to 50℃, the CO2 extraction flow rate to 20 L / min, and the extraction time to 3 h. The volume ratio of supercritical CO2 fluid to mixed entrainer is (2-3):1. The mixed entrainer is composed of anhydrous ethanol and prickly pear fruit oil. After extraction, remove the fluid and anhydrous ethanol under reduced pressure to obtain psyllium seed extract.

[0012] More preferably, the mixed entrainer in step 2 is a mixture of anhydrous ethanol and sea buckthorn oil in a volume ratio of (2.5-3):1.

[0013] Secondly, the present invention provides the application of the soothing composition containing sea buckthorn oil and delaying discoloration as described in the first aspect in the preparation of skin care products with soothing, anti-inflammatory and antioxidant effects.

[0014] Preferably, the amount of the soothing composition added to the skin care product is 0.1-1%.

[0015] Thirdly, the present invention provides a soothing serum containing the soothing composition described in the first aspect; The serum also includes cosmetic-acceptable excipients and solvents.

[0016] Fourthly, the present invention provides a method for preparing the aforementioned serum, the method comprising the following steps: The soothing composition, excipients, and solvent are mixed evenly to obtain the serum.

[0017] In this invention: The oil from sea buckthorn fruit is rich in fatty acids such as oleic acid and linoleic acid, which are similar in structure to human sebum, as well as active substances such as vitamin E, phytosterols, polyphenols, and squalene. This allows it to deeply moisturize and nourish, soothe inflammation, and possess antioxidant and anti-aging properties. It is also highly skin-friendly and safe, making it especially suitable for sensitive skin and skin with a damaged barrier. In this invention, the sea buckthorn fruit oil works synergistically with other ingredients, not only enhancing the skin compatibility of the composition but also inhibiting oxidative discoloration, which is the core foundation for ensuring product stability and soothing efficacy.

[0018] Terminalia chebula fruit extract is rich in antioxidants such as tannins and polyphenols, which can scavenge free radicals, inhibit the release of inflammatory factors, and enhance the anti-inflammatory effect of the composition. In this invention, Terminalia chebula fruit extract is prepared by a specific supercritical CO2 extraction process, and the extraction method using sea buckthorn fruit oil as an entrainer makes its active ingredients more compatible with sea buckthorn fruit oil, thereby exerting a soothing effect.

[0019] Ceramide NP from sea buckthorn fruit oil is a key ingredient in skin barrier repair. It can replenish lipids in the stratum corneum, strengthen the barrier function, reduce the impact of external stimuli on the skin, and help enhance the soothing effect. It works synergistically with sea buckthorn fruit oil to optimize the lipid structure of the composition and enhance the skin's absorption of the active ingredients.

[0020] Plantago seed extract contains polysaccharides and flavonoids, exhibiting excellent anti-inflammatory and soothing effects. It can synergistically work with Terminalia chebula fruit extract to inhibit the release of inflammatory factors, enhancing the overall anti-inflammatory efficacy of the composition. The use of supercritical CO2 extraction with Prickly pear fruit oil as an entrainer ensures efficient retention of its active ingredients and excellent compatibility with other raw materials, further improving the soothing efficacy of the composition.

[0021] The beneficial effects of this invention are: 1. The composition provided by the present invention, through the synergistic combination of four core raw materials—Stachys affinis fruit oil, Terminalia chebula fruit extract, Stachys affinis fruit oil ceramide NP, and Plantago asiatica seed extract—has a high inhibitory effect on LPS-induced inflammation. The optimal ratio of inflammatory factors inhibits the inflammation factor by 86.33%, which is close to the positive control and superior to the comparative composition that lacks any core raw material or replaces the raw material. 2. After stability testing, the serum containing the soothing composition provided by the present invention showed no change in appearance, while the comparative samples in which the sea buckthorn oil was replaced with other oils all showed a darkening of color, proving that the sea buckthorn oil in the composition can effectively delay the oxidation and discoloration of skin care products and extend the shelf life of active ingredients. Attached Figure Description

[0022] To better illustrate the purpose, technical solution, and advantages of the present invention, the present invention will be further described below in conjunction with the accompanying drawings.

[0023] Figure 1 Comparison of the appearance of serums 1-3 after being placed at 45±1℃ for 3 months; Figure 2 Comparison photos of the appearance of serums 1-3 after being stored at room temperature for 3 months; Figure 3 Comparison photos of the appearance of serums 1-3 after being placed under light for 3 months. Detailed Implementation

[0024] To better illustrate the objectives, technical solutions, and advantages of this invention, the invention will be further described below with reference to specific embodiments. Those skilled in the art should understand that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.

[0025] Unless otherwise specified, the test methods used in the examples and comparative examples are conventional methods; the materials and reagents used are commercially available unless otherwise specified; and the percentages mentioned in the examples and comparative examples are mass percentages unless otherwise specified.

[0026] I. In this invention Prickly pear fruit oil: also known as flat-kernel wood oil, purchased from Yunnan Yingge Biotechnology Co., Ltd. This product is processed by alkali refining, decolorization, temporary storage and deodorization, which increases the relative content of fatty acids and yields high-quality flat-kernel wood oil. Ceramide NP from sea buckthorn fruit oil: prepared according to the preparation method in Example 3 of Chinese Patent CN116003286A.

[0027] The specific preparation method of Terminalia chebula fruit extract is as follows: Step 1. Place the dried Terminalia chebula fruit in a high-speed grinder and grind it. Pass it through a 60-mesh sieve to obtain Terminalia chebula fruit powder. Step 2. Place the Terminalia chebula fruit powder in a supercritical CO2 extraction vessel for extraction. Set the extraction pressure to 22 MPa, the extraction temperature to 44℃, the CO2 extraction flow rate to 23 L / min, and the extraction time to 3 h. The volume ratio of supercritical CO2 fluid to mixed entrainer is 6:1. The mixed entrainer is composed of anhydrous ethanol and Prickly pear fruit oil mixed at a volume ratio of 2:1. After extraction, remove the fluid and anhydrous ethanol under reduced pressure to obtain Terminalia chebula fruit extract with Prickly pear fruit oil as the carrier solvent.

[0028] The specific preparation method of Plantago asiatica seed extract is as follows: Step 1. Place dried psyllium seeds in a high-speed grinder and grind them, then pass them through a 60-mesh sieve to obtain psyllium seed powder; Step 2. Place the psyllium seed powder in a supercritical CO2 extraction vessel for extraction. Set the extraction pressure to 28 MPa, the extraction temperature to 50℃, the CO2 extraction flow rate to 20 L / min, and the extraction time to 3 h. The volume ratio of supercritical CO2 fluid to mixed entrainer is 2.5:1. The mixed entrainer is composed of anhydrous ethanol and sea buckthorn oil mixed at a volume ratio of 2.8:1. After extraction, remove the fluid and anhydrous ethanol under reduced pressure to obtain psyllium seed extract with sea buckthorn oil as the carrier solvent.

[0029] II. Contains a soothing composition with prickly pear oil to delay discoloration. The specific preparation methods of compositions 1-4 are as follows: By compounding the raw materials according to the mass ratio in Table 1, a soothing composition containing sea buckthorn fruit oil and delaying discoloration was obtained.

[0030] Table 1. Mass ratio of raw materials for compositions 1-4 Prickly pear oil 10 20 25 30 Terminalia chebula fruit extract 1 2.2 2.3 3 Prickly pear fruit oil ceramide NP 0.006 0.02 0.15 0.2 Plantago seed extract 0.01 0.02 0.04 0.05 The specific preparation methods of comparative compositions 1-4 are as follows: Based on the formulation of composition 3, adjustments were made, specifically according to the mass ratio of raw materials in Table 2, to obtain comparative compositions 1-4.

[0031] Table 2 Comparative Compositions 1-4 Raw Material Mass Ratio Prickly pear oil 25 25 25 25 Terminalia chebula fruit extract / 2.3 2.3 0.04 Prickly pear oil ceramide NP 0.15 / 0.15 0.15 Plantago seed extract 0.04 0.04 / 2.3 Note: " / " in the table indicates no addition.

[0032] The specific preparation methods for comparative compositions 5-6 are as follows: Replace the sea buckthorn fruit oil in composition 3 with caprylic / capric triglycerides or macadamia seed oil, and compound them according to the mass ratio of the raw materials in Table 3 to obtain comparative compositions 5-6.

[0033] Table 3 Comparative Composition 5-6 Raw Material Mass Ratio Caprylic / Capric Triglyceride 25 / Macadamia seed oil / 25 Terminalia chebula fruit extract 2.3 2.3 Prickly pear oil ceramide NP 0.15 0.15 Plantago seed extract 0.04 0.04 Note: " / " in the table indicates no addition.

[0034] The specific preparation methods for comparative compositions 7-8 are as follows: Replace the Terminalia chebula fruit extract and Plantago asiatica seed extract in composition 3 with Terminalia chebula fruit extract ① and Plantago asiatica seed extract ① respectively, and compound them according to the mass ratio of raw materials in Table 4 to obtain comparative compositions 7-8. The preparation method of Terminalia chebula fruit extract ① is the same as that of Terminalia chebula fruit extract in "I. In this invention", except that the Prickly pear fruit oil in the mixed entrainer in step 2 is replaced with soybean oil, and the rest remains the same. The preparation method of Plantago seed extract ① is the same as that in "I. Preparation method of Plantago seed extract in this invention", except that the Prickly pear oil in the mixed entrainer in step 2 is replaced with soybean oil, and the rest remains the same.

[0035] Table 4 Comparative Composition 7-8 Raw Material Mass Ratio Prickly pear oil 25 25 Terminalia chebula fruit extract / 2.3 Terminalia chebula fruit extract① 2.3 / Prickly pear oil ceramide NP 0.15 0.15 Plantago seed extract 0.04 / Plantago seed extract ① / 0.04 Note: " / " in the table indicates no addition.

[0036] III. Performance Testing

[0037] 1. Relief Test 1.1 Cell Culture RAW264.7 macrophages were used in DMEM high-glucose medium containing 10% fetal bovine serum, 100 U / mL penicillin, and 100 μg / mL streptomycin. Cells were cultured at 37°C in a 5% CO2 incubator. Cells were passaged when confluence reached 80%–90%, and at least once before the formal experiment.

[0038] 1.2 Cell viability assay Seeding density: Logarithmic growth phase cells were seeded at a density of 1.5 × 10⁻⁶. 4 / wells were inoculated into 96-well plates and incubated adherently for 24 hours.

[0039] Test samples: Compositions 1-4 and control compositions 1-8 were dissolved in DMSO to obtain corresponding high-concentration test stock solutions. Then, a certain amount of the high-concentration test stock solution was mixed with the culture medium to prepare test samples containing different mass fractions of the composition.

[0040] The test sample concentration gradient consisted of five different mass fractions: 0.0001%, 0.0005%, 0.001%, 0.005%, and 0.01%. These mass fractions represent the mass fractions of the compositions (compositions 1-4 and comparative compositions 1-8) in the system.

[0041] Grouping: Blank group (culture medium only), control group (cells + culture medium, no sample), sample group (cells + test samples of different concentrations).

[0042] Detection method: After culturing for 24 hours, discard the supernatant, add CCK-8 reagent and incubate for 1 hour. Measure the absorbance at 450 nm and calculate the cell viability.

[0043] Determination of safe concentration: The highest concentration with a cell viability of ≥90% was selected as the concentration for subsequent soothing tests, and was finally determined to be 0.001%.

[0044] 1.3 Lipopolysaccharide (LPS)-induced inflammation test Group setup: blank group (culture medium only), stimulation group (cells + 1 μg / mL LPS), positive control group (cells + 1 μg / mL LPS + 0.01% dexamethasone), and sample group (cells + 1 μg / mL LPS + 0.001% test sample). Each group was repeated 5 times.

[0045] Culture and detection: Mouse RAW264.7 macrophages in the logarithmic growth phase were cultured at 1.5 × 10⁻⁶ cells / cells. 4 / wells were seeded in 96-well plates and incubated in a 37°C, 5% CO2 incubator for 24 h. Then, the drugs were co-incubated according to the above grouping. After 24 h of incubation, the supernatant of each group was collected and the NO content was detected by ELISA kit. The inhibition rate was calculated (inhibition rate = (stimulation group content - sample group content) / (stimulation group content - blank group content) × 100%).

[0046] 1.4 Test Results Table 5 Test Results ( (n=5) Blank group 4.26±0.45 / Stimulation group (LPS) 16.85±1.18 / Positive control group 5.34±0.64 91.45% Composition 1 10.22±1.23 52.71% Composition 2 8.76±0.68 64.26% Composition 3 5.98±0.63 86.33% Composition 4 6.96±0.65 78.60% Comparative composition 1 12.12±0.81 37.61% Comparative composition 2 12.81±1.32 32.12% Comparative composition 3 13.56±1.82 26.16% Comparative composition 4 9.43±0.78 58.95% Comparative composition 5 15.48±1.16 10.85% Comparative composition 6 12.72±1.19 32.78% Comparative composition 7 7.22±0.75 76.51% Comparative composition 8 7.68±0.90 72.83% 1.5 Results Analysis According to the test results in Table 5: Comparative compositions 1-3, which lacked Terminalia chebula fruit extract, Prickly pear fruit oil ceramide NP, and Plantago asiatica seed extract, respectively, had inflammation inhibition rates of only 37.61%, 32.12%, and 26.16%, respectively, which were far lower than those of composition 3 with the complete formula. After adjusting the protective mass ratio claimed in this invention, the inhibition rate of comparative composition 4 dropped to 58.95%, proving that the specific ratio of the four raw materials is the key to highly effective anti-inflammatory effects.

[0047] Compared with compositions 5-6, where sea buckthorn fruit oil was replaced with caprylic / capric triglycerides and macadamia seed oil, the inflammation inhibition rates were only 10.85% and 32.78%, respectively. This indicates that the lipid composition and active ingredients of sea buckthorn fruit oil are the core of its anti-inflammatory efficacy, and cannot be replaced by other oils.

[0048] Compared with compositions 7-8, which used soybean oil instead of sea buckthorn oil as an entrainer to prepare extracts, the inhibition rate decreased to 76.51% and 72.83%, respectively, which was lower than that of composition 3, which used sea buckthorn oil as an entrainer. This proves that the choice of entrainer in the extraction process directly affects the activity of the extract, and thus affects the overall efficacy of the composition.

[0049] 2. Stability Test 2.1 Preparation of the serum The above-mentioned composition 3 and comparative compositions 5 and 6 were prepared into an essence by the following preparation method, and the effects of composition 3, comparative composition 5 and comparative composition 6 on the stability of the essence were evaluated.

[0050] The specific preparation method for the serum is as follows: Weigh the raw materials precisely according to the percentage of mass in Table 6; Step 1. Heat squalane, polydimethylsiloxane and polyglycerol-10 distearate in a water bath to 70-80℃ and stir at 100 r / min until homogeneous to obtain mixture A; Step 2. Cool mixture A to 50-60℃, add composition 3 / comparative composition 5 / comparative composition 6, and stir at 100r / min to mix evenly to obtain mixture B; Step 3. Mix sodium hyaluronate, acrylate / C10-30 alkanol acrylate crosspolymer and deionized water at 100 r / min until homogeneous to obtain mixture C; Step 4. Add mixture B to mixture C and homogenize at 2000-3000 r / min for 20 min. Then add p-hydroxyacetophenone, which has been dissolved in butanediol and 1,2-hexanediol, and stir at 200 r / min until homogeneous. Finally, add arginine to adjust the pH to 6.5-7.0, filter, and bottle to obtain the essence.

[0051] Table 6. Percentage of raw materials in the serum (%) Butylene glycol 5 5 5 squalane 1 1 1 polydimethylsiloxane 2.1 2.1 2.1 1,2-Hexanediol 0.5 0.5 0.5 Polyglycerol-10 distearate 0.3 0.3 0.3 Acrylic (ester) crosspolymers / C10-30 alkanol acrylate crosspolymers 0.31 0.31 0.31 Sodium hyaluronate 0.05 0.05 0.05 Composition 3 0.2 / / Comparative composition 5 / 0.2 / Comparative composition 6 / / 0.2 p-Hydroxyacetophenone 0.5 0.5 0.5 Arginine 0.25 0.25 0.25 Deionized water Add to 100 Add to 100 Add to 100 2.2 Stability Test High-temperature test: The constant temperature incubator was adjusted to 45±1℃. The previously prepared essence solutions 1-3 were divided into three transparent glass bottles, each containing 20mL of the essence. The bottles were sealed and placed in the constant temperature incubator. After 3 months, the bottles were removed, allowed to return to room temperature, and the changes in appearance were observed. The test results are shown in Table 7. Figure 1 .

[0052] Room temperature test: The prepared essences 1-3 were divided into three transparent glass bottles, each containing 20 mL of the essence. After sealing, the bottles were left at room temperature for 3 months. The changes in the appearance of the samples were then observed. The test results are shown in Table 7 and 8. Figure 2 .

[0053] Light Illumination Test: A lighting device was installed 20-30cm above the experimental platform for the test. The lighting conditions were set to LED lights (color temperature 6000K) and illuminance (300lx) to meet the test requirements. The previously prepared essences 1-3 were divided into three transparent glass bottles, each containing 20mL, and sealed. The bottles were then placed under the light conditions. After 3 months, the bottles were removed, brought to room temperature, and the appearance changes were observed. The test results are shown in Table 7. Figure 3 .

[0054] Table 7 Stability Test Results Serum 1 constant constant constant Stablize Serum 2 The color darkened The color darkened The color darkened Unstable Serum 3 The color darkened The color darkened The color darkened Unstable Results analysis: According to the test results in Table 7, serum 1 remained stable under all three test conditions, while serums 2 and 3 showed a darkening of color. This indicates that the prickly pear oil is not only an effective ingredient, but also can inhibit the oxidation and discoloration of other ingredients in the product through its antioxidant properties, thus ensuring the stability of the product's appearance.

[0055] Finally, it should be noted that the above descriptions are merely preferred embodiments of the present invention and are not intended to limit the present invention. Although the present invention has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present invention should be included within the protection scope of the present invention.

Claims

1. A soothing composition containing sea buckthorn fruit oil and delaying discoloration, characterized in that, The soothing composition contains the following components in parts by weight: 10-30 parts of sea buckthorn fruit oil; Terminalia chebula fruit extract 1-3 parts; Ceramide NP in sea buckthorn fruit oil: 0.006–0.2 parts; Plantago seed extract 0.01–0.05 parts.

2. The soothing composition according to claim 1, characterized in that, The soothing composition contains the following components in parts by weight: 20-25 parts of sea buckthorn fruit oil; Terminalia chebula fruit extract, 2.2–2.3 parts; Ceramide NP in sea buckthorn fruit oil: 0.02–0.15 parts; Plantago seed extract 0.02–0.04 parts.

3. The soothing composition according to claim 2, characterized in that, The preparation method of the Terminalia chebula fruit extract includes the following steps: Step 1: Place the dried Terminalia chebula fruit in a high-speed grinder and grind it. Then pass it through a 60-mesh sieve to obtain Terminalia chebula fruit powder. Step 2: Place the Terminalia chebula fruit powder in a supercritical CO2 extraction vessel for extraction. Set the extraction pressure to 22 MPa, the extraction temperature to 40-50℃, the CO2 extraction flow rate to 22-25 L / min, and the extraction time to 2-3 h. The volume ratio of supercritical CO2 fluid to mixed entrainer is (5-6):

1. The mixed entrainer is composed of anhydrous ethanol and Prickly pear fruit oil. After extraction, remove the fluid and anhydrous ethanol under reduced pressure to obtain Terminalia chebula fruit extract.

4. The soothing composition according to claim 3, characterized in that, The mixed entrainer in step 2 is made by mixing anhydrous ethanol and sea buckthorn oil in a volume ratio of (1.8-2.1):

1.

5. The soothing composition according to claim 2, characterized in that, The preparation method of the Terminalia chebula fruit extract includes the following steps: Step 1: Place dried psyllium seeds in a high-speed grinder and grind them. Pass the powder through a 60-mesh sieve to obtain psyllium seed powder. Step 2: Place the psyllium seed powder in a supercritical CO2 extraction vessel for extraction. Set the extraction pressure to 28 MPa, the extraction temperature to 50℃, the CO2 extraction flow rate to 20 L / min, and the extraction time to 3 h. The volume ratio of supercritical CO2 fluid to mixed entrainer is (2-3):

1. The mixed entrainer is composed of anhydrous ethanol and prickly pear fruit oil. After extraction, remove the fluid and anhydrous ethanol under reduced pressure to obtain psyllium seed extract.

6. The soothing composition according to claim 5, characterized in that, The mixed entrainer in step 2 is made by mixing anhydrous ethanol and sea buckthorn oil in a volume ratio of (2.5-3):

1.

7. The use of the soothing composition containing sea buckthorn oil and delaying discoloration as described in any one of claims 1-6 in the preparation of skin care products with soothing, anti-inflammatory and antioxidant effects.

8. The application according to claim 7, characterized in that, The soothing composition is added to the skin care product at an amount of 0.1-1%.

9. A soothing serum, characterized in that, The serum contains the soothing composition according to any one of claims 1-6; The serum also includes cosmetic-acceptable excipients and solvents.

10. A method for preparing the essence according to claim 9, characterized in that, The preparation method includes the following steps: The soothing composition, excipients, and solvent are mixed evenly to obtain the serum.

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