Automatic filter paper punching instrument suitable for genetic disease molecular screening

Abstract

The invention provides an automatic filter paper punching instrument suitable for genetic disease molecular screening, which comprises a base, a test tube groove formed in the middle of the base, a test tube rack arranged in the test tube groove, a punching disc arranged on the base above the test tube rack, punching holes formed in the punching disc, an overturning head arranged on the base, and at least two punching columns arranged on the overturning head, a stamping hole is formed in the stamping disc; a first driving device and a second driving device are arranged on the overturning head; a disinfection alcohol lamp is arranged at the rear part of the base; the instruction output end of the controller is electrically connected with the first driving device, the second driving device and the alcohol lamp ignition device. And a control screen. A plurality of punching columns are arranged on the overturning head, a plurality of punching holes are formed in the punching disc, a plurality of test tube racks are arranged on the test tube grooves below the punching disc, a plurality of test tubes are mounted on the test tube racks, during use, a plurality of blood spots are placed on the punching disc, a plurality of blood spot samples can be punched at a time, and the working efficiency is greatly improved.

Description

Technical Field

[0001] This application relates to the field of medical testing instruments, specifically an automatic filter paper punching device suitable for molecular screening of genetic diseases. Background Technology

[0002] Newborn screening for inherited metabolic disorders is performed between 24 hours and 28 days after birth. This allows for the timely detection of inherited metabolic disorders such as phenylketonuria, congenital hypothyroidism, and abnormalities in glucose-6-phosphate dehydrogenase. Early diagnosis and treatment are crucial when affected newborns show no clinical symptoms or only mild symptoms, preventing irreversible damage to organs and tissues, and avoiding death or severe organ dysfunction.

[0003] During screening, nurses collect blood from newborns' heels and place it on filter paper, forming multiple uniform, circular blood spots—these are blood patches. Before screening, a special instrument is used to punch holes in the blood patches, pressing the blood spots and the paper underneath them through. Currently, the punching machine can only punch one blood spot at a time, resulting in low efficiency. During peak newborn screening periods, the punching workload is very large and slow, affecting the output of subsequent screening results. Therefore, there is an urgent need for a high-efficiency automatic filter paper punching device. Summary of the Invention

[0004] The purpose of this application is to propose an automatic filter paper puncher with high punching efficiency suitable for molecular screening of genetic diseases.

[0005] The purpose of this application is achieved as follows: an automatic filter paper punching device suitable for molecular screening of genetic diseases.

[0006] include:

[0007] Base

[0008] The base has a test tube slot in the middle.

[0009] The test tube holder is equipped with a test tube rack inside.

[0010] The base above the test tube rack is equipped with a stamping plate, which has stamping holes.

[0011] The base is equipped with a flip head, and the flip head has at least two perforated posts.

[0012] The stamping plate has stamping holes corresponding to the number of punching pins;

[0013] The flipping head is equipped with a first drive device for driving the punching column to rotate and a second drive device for driving the punching column to move vertically.

[0014] The base is equipped with a disinfecting alcohol lamp at the rear, and the disinfecting alcohol lamp has a lamp head corresponding to the number of punched posts;

[0015] The controller's command output terminal is electrically connected to the first drive device, the second drive device, and the alcohol lamp ignition device, respectively.

[0016] The control panel is electrically connected to the signal input terminal of the controller.

[0017] Furthermore, the disinfectant alcohol lamp is rectangular in shape, including a rectangular bottle containing alcohol, a lamp head at the top of the bottle, and a wick that communicates with the alcohol inside the bottle.

[0018] Furthermore, a bottle cap is located on the top left side of the bottle, and a liquid level observation window is located on the left side of the bottle.

[0019] Furthermore, the lamp holder is a ceramic lamp holder.

[0020] Furthermore, the first drive device is a geared motor.

[0021] Furthermore, the second drive device is an electric actuator.

[0022] Furthermore, it also includes test tubes for receiving sample pieces, which are installed inside a test tube rack.

[0023] Furthermore, the flipping head is equipped with 8 punching posts, the stamping plate is equipped with 8 stamping holes corresponding to the number of punching posts, and the disinfectant alcohol lamp is equipped with 8 lamp heads corresponding to the number of punching posts.

[0024] Furthermore, an opening is provided on the rear side of the base, through which the disinfectant alcohol lamp is installed inside the base.

[0025] This application has the following beneficial effects:

[0026] This application features a rotating head with multiple punching posts, a stamping plate with multiple stamping holes, and a test tube rack on the test tube slot under the stamping plate. Multiple test tubes are installed on the test tube rack. In use, multiple blood smears are placed on the stamping plate, and multiple blood smear samples can be stamped at one time, greatly improving work efficiency. Attached Figure Description

[0027] The specific structure of this application is given by the following figures and embodiments:

[0028] Figure 1 This is a first-view three-dimensional structural diagram of Embodiment 1 of this application;

[0029] Figure 2 This is a second-view three-dimensional structural diagram of Embodiment 1 of this application;

[0030] Figure 3 This is a schematic diagram of the left view structure of Embodiment 1 of this application;

[0031] Figure 4 This is a three-dimensional structural diagram of the alcohol disinfection lamp in Embodiment 1 of this application.

[0032] Legend: 1. Base, 2. Test tube trough, 3. Test tube rack, 4. Stamping plate, 5. Stamping hole, 6. Flipping head, 7. Drilling column, 8. Disinfecting alcohol lamp, 9. Control panel, 10. Bottle body, 11. Lamp head, 12. Lamp wick, 13. Alcohol lamp ignition device, 14. Liquid level observation window. Detailed Implementation

[0033] This application is not limited to the following embodiments, and the specific implementation method can be determined according to the technical solution of this application and the actual situation.

[0034] Example: An automatic filter paper punching device suitable for molecular screening of genetic diseases, comprising: a base 1, a test tube slot in the middle of the base, a test tube rack 3 inside the test tube slot, a stamping plate 4 on the base above the test tube rack, stamping holes 5 on the stamping plate, a flipping head 6 on the base, at least two punching posts 7 on the flipping head, and punching holes on the stamping plate corresponding to the number of punching posts; the flipping head is provided with a first driving device for driving the punching posts to rotate and a second driving device for driving the punching posts to move vertically;

[0035] The base has a disinfecting alcohol lamp 8 at the rear, with lamp heads corresponding to the number of punching posts; a controller, whose command output is electrically connected to the first drive device, the second drive device, and the alcohol lamp ignition device; and a control panel 9, whose signal output is electrically connected to the signal input of the controller. This application features a flip head with multiple punching posts, a stamping plate with multiple stamping holes, and a test tube rack on the test tube groove under the stamping plate, with multiple test tubes mounted on the racks. In use, multiple blood smears are placed on the stamping plate, allowing for the stamping of multiple blood smear samples at once, greatly improving work efficiency. The alcohol lamp ignition device can be based on the working principle of a lighter.

[0036] Furthermore, the disinfectant alcohol lamp is rectangular in shape, including a rectangular bottle 10 containing alcohol, a lamp head 11 at the top of the bottle, and a wick 12 connected to the alcohol inside the bottle. The rectangular bottle shape is designed to fit the structure of the base, and its working principle is the same as that of a traditional alcohol lamp.

[0037] Furthermore, an alcohol lamp ignition device 13 is provided on the top left side of the bottle, and a liquid level observation window 14 is provided on the left side of the bottle. The alcohol lamp ignition device can ignite automatically, and the liquid level observation window allows for observation of the alcohol level inside the bottle at any time.

[0038] Furthermore, the lamp holder is a ceramic lamp holder.

[0039] Furthermore, the first driving device is a geared motor. The geared motor can drive the tilting head to rotate, realizing the action of tilting it to disinfect above the alcohol disinfection lamp and then returning.

[0040] Furthermore, the second drive device is an electric linear actuator. The electric linear actuator can realize the stamping action, with rapid action and precise control.

[0041] Furthermore, it also includes test tubes for receiving the sample pieces, which are installed inside a test tube rack. The bloodstain pieces that are punched off will fall into the test tubes.

[0042] Furthermore, the flipping head has eight punching posts, the stamping plate has eight stamping holes corresponding to the number of punching posts, and the disinfectant alcohol lamp has eight lamp heads corresponding to the number of punching posts. This invention increases the number of punching posts, stamping holes, and lamp heads, significantly improving stamping efficiency.

[0043] Furthermore, an opening is provided on the rear side of the base, through which the alcohol disinfectant lamp is installed inside the base. This facilitates the placement and removal of the alcohol disinfectant lamp.

[0044] The method of use of this application is as follows: After the equipment is powered on, the controller controls the alcohol lamp ignition device to ignite all eight lamp heads and wicks of the alcohol lamp. Place the blood card to be stamped on the stamping plate, start the equipment, and the controller operates the first drive device. The first drive device drives the flipping head to rotate 90 degrees backward, so that the punching column is placed horizontally above the alcohol lamp for sterilization. After sterilization, the controller operates the flipping head to rotate 90 degrees forward to reset. Then the controller operates the second drive device, which drives the punching column to punch downward, pressing the blood spot on the blood card and letting it fall into the test tube below. This completes one stamping operation. Repeating the above steps can quickly and efficiently realize the stamping operation of blood cards, greatly improving work efficiency.

[0045] The above description is merely an example for clearly illustrating this application and is not intended to limit the implementation of this application. Any obvious variations or modifications derived from the technical solutions of this application are still within the protection scope of this application.

Claims

1. An automatic puncher for filter paper sheets suitable for molecular screening of genetic diseases, characterized in that, It comprises: a base, a test tube slot is arranged in the middle of the base, a test tube rack is arranged inside the test tube slot, a punching disc is arranged above the test tube rack of the base, and the punching disc is provided with punching holes, a turnover head is arranged on the base, and the turnover head is provided with at least two punching columns, the punching disc is provided with punching holes corresponding to the number of punching columns; the turnover head is provided with a first driving device for driving the punching columns to rotate and a second driving device for driving the punching columns to move vertically; a disinfectant alcohol lamp is arranged at the back of the base, and the disinfectant alcohol lamp is provided with lamp heads corresponding to the number of punching columns; a controller, the command output end of the controller is electrically connected with the first driving device, the second driving device and the alcohol lamp ignition device respectively; a control screen, the signal output end of the control screen is electrically connected with the signal input end of the controller.

2. The automatic puncher for filter paper sheets suitable for molecular screening of genetic diseases according to claim 1, characterized in that, The disinfectant alcohol lamp is in the shape of a cuboid, comprising a cuboid-shaped bottle body, the bottle body is internally provided with alcohol, the top of the bottle body is provided with a lamp head, and the lamp head is provided with a lamp wick in communication with the alcohol inside the bottle body.

3. The method of claim 2, wherein, A bottle cap is arranged at the top of the left side of the bottle body, and a liquid level observation window is arranged on the left side of the bottle body.

4. The automatic puncher for filter paper sheets suitable for molecular screening of genetic diseases according to claim 2, characterized in that, The lamp head is a ceramic lamp head.

5. The automatic puncher for filter paper sheets suitable for molecular screening of genetic diseases according to claim 1, characterized in that, The first driving device is a speed reducer.

6. The automatic puncher for filter paper sheets suitable for molecular screening of genetic diseases according to claim 1, characterized in that, The second driving device is an electric push rod.

7. The automatic puncher for filter paper sheets suitable for molecular screening of genetic diseases according to claim 1, characterized in that, It also includes a test tube for receiving a sample, and the test tube is installed in the test tube rack.

8. The automatic puncher for filter paper sheets suitable for molecular screening of genetic diseases according to claim 1, characterized in that, The turnover head is provided with eight punching columns, the punching disc is provided with eight punching holes corresponding to the number of punching columns, and the disinfectant alcohol lamp is provided with eight lamp heads corresponding to the number of punching columns.

9. The automatic puncher for filter paper sheets suitable for molecular screening of genetic diseases according to claim 1, characterized in that, An opening is arranged on the side surface of the back of the base, and the disinfectant alcohol lamp is installed in the base through the opening.

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