用于宫颈胃型腺癌类器官的培养基及其应用
By constructing a culture medium for cervical gastric adenocarcinoma organoids containing specific additives, the problem of the lack of in vitro models for cervical gastric adenocarcinoma research has been solved. Stable culture and rapid expansion of cervical gastric adenocarcinoma organoids have been achieved, providing a research platform for personalized treatment and improving treatment efficacy and prognosis.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- BIOGENOUS BIOTECH INC
- Filing Date
- 2026-02-24
- Publication Date
- 2026-07-17
AI Technical Summary
Current technologies lack effective in vitro models for the study of cervical gastric adenocarcinoma, resulting in a lack of evidence-based medicine for treatment, poor treatment outcomes, high recurrence rates, and poor prognosis.
A culture medium for cervical gastric adenocarcinoma organoids is provided, containing Neuregulin 1 and other additives such as B27, Y-27632, estradiol, A83-01, EGF, Noggin, R-Spondin 1, hydrocortisone, Forskolin, and wnt3a, for constructing cervical gastric adenocarcinoma organoids, mimicking the in vivo microenvironment, maintaining tissue morphological characteristics, and promoting organoid expansion.
We successfully constructed and maintained organoids of cervical gastric adenocarcinoma, simulating a real tumor environment, providing a platform for personalized drug screening and treatment, improving treatment targeting, reducing recurrence rate, and improving prognosis.
Smart Images
Figure CN121699873B_ABST