一种调控马铃薯和番茄中甾体糖苷生物碱含量的转录因子BSB2及其应用

By identifying and validating the transcription factor BSB2, a transcriptional complex with GAME9 and others was formed, which synergistically regulates the synthesis of steroidal glycoside alkaloids in Solanaceae crops. This solves the problem of incomplete regulation in existing technologies and improves crop quality and safety.

CN121824715BActive Publication Date: 2026-07-17SANYA NATIONAL INSTITUTE OF SOUTHERN BREEDING CHINESE ACADEMY OF AGRICULTURAL SCIENCES
View PDF 1 Cites 0 Cited by

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
SANYA NATIONAL INSTITUTE OF SOUTHERN BREEDING CHINESE ACADEMY OF AGRICULTURAL SCIENCES
Filing Date
2026-03-06
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

Existing technologies are insufficient to fully understand and regulate the synthesis mechanism of steroidal glycoalkaloids (SGAs) in solanaceous crops, making it impossible to precisely improve their content and limiting the improvement of crop quality and food safety.

Method used

The function of transcription factor BSB2 was identified and verified. Through gene editing technology, the synthesis of steroidal glycoside alkaloids in potatoes and tomatoes was regulated to form a transcriptional complex with transcription factors such as GAME9, which synergistically regulates the synthesis pathway of SGAs.

Benefits of technology

It provides direct molecular targets for targeted improvement of steroidal glycoside alkaloid content in Solanaceae plants, thereby increasing breeding efficiency, ensuring food quality and safety, and expanding the applicability of the regulatory mechanism.

✦ Generated by Eureka AI based on patent content.

Smart Images

  • Figure CN121824715B_ABST
    Figure CN121824715B_ABST
Patent Text Reader

Abstract

本申请属于农业生物技术领域,具体涉及对马铃薯和番茄的甾体糖苷生物碱积累具有调控作用的转录因子BSB2及其应用。包括马铃薯来源的StBSB2和番茄来源的同源转录因子SlBSB2;其中,马铃薯中的StBSB2由马铃薯基因Soltu.DM.04G032190编码,该马铃薯基因Soltu.DM.04G032190的编码区核苷酸序列如SEQ ID NO.1所示;番茄中的SlBSB2由番茄基因Solyc04g077480编码,该番茄基因Solyc04g077480的编码区核苷酸序列如SEQ ID NO.2所示。本申请明确了BSB2可与GAME9、BSB形成转录复合体,在光信号刺激下激活下游SGAs合成相关基因的表达,从而正调控马铃薯和番茄中主要SGAs的合成。通过调控BSB2基因表达及其功能,可实现对茄科植物中甾体糖苷生物碱含量的定向改良。本申请为理解茄科植物中SGAs的转录调控机制提供了新见解,也为马铃薯采后品质保持及分子育种提供新靶标。
Need to check novelty before this filing date? Find Prior Art