一种光引发的合成氨基苯酚类化合物的方法及应用
The synthesis of aminophenol via a one-step visible light catalysis using 1-hydroxybenzotriazole and cyclohexenone compounds solves the problems of lengthy steps and the use of highly toxic reagents in existing methods, achieving a highly efficient and selective synthesis of aminophenol with potential for pharmaceutical and antibacterial applications.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- RES INST OF TEA YUNNAN ACAD OF AGRI SCI
- Filing Date
- 2026-03-18
- Publication Date
- 2026-07-17
AI Technical Summary
Existing methods for synthesizing aminophenol are lengthy, difficult to control regioselectivity, and require the use of transition metal catalysts and highly toxic reagents, which limits its application in drug development and industrial production.
Using 1-hydroxybenzotriazole and cyclohexenone compounds as raw materials, aminophenol compounds were synthesized in a single step under visible light catalysis. A base was used as a catalyst, and the efficient and highly selective construction was achieved through photocatalysis.
The efficient synthesis of aminophenol compounds was achieved under mild conditions, with high yield and chemoselectivity. The synthesized compounds showed good inhibitory effects against Colloidal anthrax, and have broad prospects for pharmaceutical and antibacterial applications.
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Figure CN121850877B_ABST