一种稳定型犬瘙痒模型构建方法及多维度评价方法
The canine pruritus model construction method, which employs rigorous screening and multi-dimensional evaluation, addresses the issues of poor model stability and insufficient adaptability in existing technologies. It achieves a canine pruritus model with high stability and wide applicability, thereby improving the efficiency and resource utilization of biomedical research.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- BEIJING GRAND SPARK PHARM TECH CO LTD
- Filing Date
- 2026-03-16
- Publication Date
- 2026-07-17
AI Technical Summary
Existing technologies for constructing and evaluating canine pruritus models suffer from poor stability, limited evaluation dimensions, and lack of scenario adaptability. This results in large fluctuations in the sensitization effect of the models, poor behavioral repeatability, and an inability to meet the needs of long-term experiments, leading to a waste of resources.
We employ a rigorous screening of experimental dogs, standardized environmental adaptation, and construction methods covering multiple types of sensitizers. Combined with a multi-dimensional evaluation system, including evaluation algorithms for physiological and pathological, behavioral stability, and scenario adaptability, we ensure the stability and applicability of the model.
It significantly improved the stability and reliability of the model, achieved accurate evaluation across all dimensions, enhanced the model's scenario adaptability and resource utilization efficiency, and promoted the standardization and industrial application of the canine pruritus model.
Smart Images
Figure CN121867152B_ABST